DK1487863T3 - Fremgangsmåde til oprensning af glycopeptidphosponatderivater - Google Patents

Fremgangsmåde til oprensning af glycopeptidphosponatderivater

Info

Publication number
DK1487863T3
DK1487863T3 DK02761476T DK02761476T DK1487863T3 DK 1487863 T3 DK1487863 T3 DK 1487863T3 DK 02761476 T DK02761476 T DK 02761476T DK 02761476 T DK02761476 T DK 02761476T DK 1487863 T3 DK1487863 T3 DK 1487863T3
Authority
DK
Denmark
Prior art keywords
glycopeptide
purification
phosphate derivatives
resin
methods
Prior art date
Application number
DK02761476T
Other languages
Danish (da)
English (en)
Inventor
Donald Schmidt Jr
Jeanmarie Donovan Sganga
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of DK1487863T3 publication Critical patent/DK1487863T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02761476T 2001-08-24 2002-08-23 Fremgangsmåde til oprensning af glycopeptidphosponatderivater DK1487863T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31471201P 2001-08-24 2001-08-24
PCT/US2002/026854 WO2003018608A2 (fr) 2001-08-24 2002-08-23 Procede de purification de derives phosphonates de glycopeptides

Publications (1)

Publication Number Publication Date
DK1487863T3 true DK1487863T3 (da) 2009-07-13

Family

ID=23221118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02761476T DK1487863T3 (da) 2001-08-24 2002-08-23 Fremgangsmåde til oprensning af glycopeptidphosponatderivater

Country Status (14)

Country Link
US (5) US7015307B2 (fr)
EP (1) EP1487863B1 (fr)
JP (1) JP4116547B2 (fr)
KR (1) KR100905009B1 (fr)
CN (1) CN100418980C (fr)
AT (1) ATE430159T1 (fr)
AU (1) AU2002326740A1 (fr)
CA (1) CA2457218C (fr)
DE (1) DE60232197D1 (fr)
DK (1) DK1487863T3 (fr)
ES (1) ES2324771T3 (fr)
NO (1) NO330734B1 (fr)
TW (1) TWI233932B (fr)
WO (1) WO2003018608A2 (fr)

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UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
TWI342312B (en) * 2003-10-22 2011-05-21 Theravance Inc Hydrochloride salts of a glycopeptide phosphonate derivative
BRPI0516657A (pt) 2004-11-29 2008-09-16 Univ Nagoya Nat Univ Corp derivados de monÈmero antibiótico de glicopeptìdeo
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
US20090069219A1 (en) * 2007-09-09 2009-03-12 Protia, Llc Deuterium-enriched telavancin
CA2710602A1 (fr) * 2007-12-26 2009-07-09 Lead Therapeutics, Inc. Nouveaux glycopeptides semi-synthetiques comme agents antibacteriens
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN103105327A (zh) * 2011-11-11 2013-05-15 中国科学院大连化学物理研究所 采用金属氧化物富集糖肽的通用方法
US9753436B2 (en) 2013-06-11 2017-09-05 Apple Inc. Rotary input mechanism for an electronic device
KR102231031B1 (ko) 2013-08-09 2021-03-23 애플 인크. 전자 디바이스용 촉각 스위치
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
US10048802B2 (en) 2014-02-12 2018-08-14 Apple Inc. Rejection of false turns of rotary inputs for electronic devices
US10190891B1 (en) 2014-07-16 2019-01-29 Apple Inc. Optical encoder for detecting rotational and axial movement
US10599101B2 (en) 2014-09-02 2020-03-24 Apple Inc. Wearable electronic device
CA2976384A1 (fr) 2015-02-23 2016-09-01 Theravance Biopharma Antibiotics Ip, Llc Doses et procedes d'administration de telavancine
CN105985412A (zh) * 2015-02-28 2016-10-05 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
JP6515185B2 (ja) 2015-03-05 2019-05-15 アップル インコーポレイテッドＡｐｐｌｅ Ｉｎｃ． 方向依存光学特性を有する光学エンコーダを有する時計、手首装着型電子デバイス及びウェラブル電子デバイス
EP3251139B1 (fr) 2015-03-08 2021-04-28 Apple Inc. Joint d'étanchéité compressible pour mécanismes d'entrée à rotation et translation
US10018966B2 (en) 2015-04-24 2018-07-10 Apple Inc. Cover member for an input mechanism of an electronic device
US9891651B2 (en) 2016-02-27 2018-02-13 Apple Inc. Rotatable input mechanism having adjustable output
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
US10551798B1 (en) 2016-05-17 2020-02-04 Apple Inc. Rotatable crown for an electronic device
US10061399B2 (en) 2016-07-15 2018-08-28 Apple Inc. Capacitive gap sensor ring for an input device
US10019097B2 (en) 2016-07-25 2018-07-10 Apple Inc. Force-detecting input structure
US10664074B2 (en) 2017-06-19 2020-05-26 Apple Inc. Contact-sensitive crown for an electronic watch
US10962935B1 (en) 2017-07-18 2021-03-30 Apple Inc. Tri-axis force sensor
US11360440B2 (en) 2018-06-25 2022-06-14 Apple Inc. Crown for an electronic watch
US11561515B2 (en) 2018-08-02 2023-01-24 Apple Inc. Crown for an electronic watch
CN211293787U (zh) 2018-08-24 2020-08-18 苹果公司 电子表
US11181863B2 (en) 2018-08-24 2021-11-23 Apple Inc. Conductive cap for watch crown
CN209625187U (zh) 2018-08-30 2019-11-12 苹果公司 电子手表和电子设备
US11194298B2 (en) 2018-08-30 2021-12-07 Apple Inc. Crown assembly for an electronic watch
US11194299B1 (en) 2019-02-12 2021-12-07 Apple Inc. Variable frictional feedback device for a digital crown of an electronic watch
US11550268B2 (en) 2020-06-02 2023-01-10 Apple Inc. Switch module for electronic crown assembly
US11983035B2 (en) 2020-06-11 2024-05-14 Apple Inc. Electronic device
US12092996B2 (en) 2021-07-16 2024-09-17 Apple Inc. Laser-based rotation sensor for a crown of an electronic watch

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US4440753A (en) 1982-03-15 1984-04-03 Eli Lilly And Company Purification of glycopeptide antibiotics using non-functional resins
US4667024A (en) 1983-07-13 1987-05-19 Smithkline Beckman Corporation Process for the preparation of purified vancomycin class antibiotics
GB8608798D0 (en) 1986-04-11 1986-05-14 Lepetit Spa Recovery of glycopeptide antibiotics from aqueous solutions
US4845104A (en) * 1986-11-20 1989-07-04 Merck & Co., Inc. Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
US4845194A (en) * 1987-02-27 1989-07-04 Eli Lilly And Company Glycopeptide recovery process
US4874843A (en) 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
US4996148A (en) * 1987-07-13 1991-02-26 Eli Lilly And Company A80407 antibiotics
JP2577133B2 (ja) 1989-11-27 1997-01-29 スティフティング フォール ド テフニスヘ ウェッテンスハッペン 船舶のプロペラ
US5149784A (en) 1990-07-10 1992-09-22 Abbott Laboratories Process for making vancomycin
US5258495A (en) 1990-07-10 1993-11-02 Abbott Laboratories Process for making vancomycin HC1
DE4039451A1 (de) * 1990-12-11 1992-06-17 Hoechst Ag Metallocene mit bicyclischen cyclopentadienderivaten als liganden, verfahren zu ihrer herstellung und ihre verwendung als katalysatoren
JP3421338B2 (ja) 1992-04-20 2003-06-30 アボツト・ラボラトリーズ バンコマイシンの製造方法
TW457248B (en) * 1994-01-28 2001-10-01 Lilly Co Eli Glycopeptide antibiotic derivatives
SI9500039B (sl) 1995-02-07 2002-02-28 Lek, Nov kombiniran postopek čiščenja Vankomicin hidroklorida
WO1998026085A1 (fr) 1996-12-11 1998-06-18 Nippon Kayaku Kabushiki Kaisha Procedes de fabrication de vancomycine
UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives

Also Published As

Publication number Publication date
JP2005505542A (ja) 2005-02-24
US20080103290A1 (en) 2008-05-01
WO2003018608A2 (fr) 2003-03-06
US7468420B2 (en) 2008-12-23
NO330734B1 (no) 2011-06-27
CN100418980C (zh) 2008-09-17
EP1487863B1 (fr) 2009-04-29
CN1671732A (zh) 2005-09-21
NO20040768L (no) 2004-04-29
US20090215673A1 (en) 2009-08-27
CA2457218A1 (fr) 2003-03-06
US20110257364A1 (en) 2011-10-20
US7015307B2 (en) 2006-03-21
ATE430159T1 (de) 2009-05-15
US20060100415A1 (en) 2006-05-11
EP1487863A2 (fr) 2004-12-22
ES2324771T3 (es) 2009-08-14
EP1487863A4 (fr) 2007-08-29
US7858583B2 (en) 2010-12-28
WO2003018608A8 (fr) 2003-04-24
US7375181B2 (en) 2008-05-20
CA2457218C (fr) 2011-08-02
WO2003018608A3 (fr) 2004-10-07
TWI233932B (en) 2005-06-11
AU2002326740A1 (en) 2003-03-10
US20030119722A1 (en) 2003-06-26
DE60232197D1 (de) 2009-06-10
KR100905009B1 (ko) 2009-06-29
JP4116547B2 (ja) 2008-07-09
KR20040028998A (ko) 2004-04-03

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