DK1455603T3 - Stimulering af in vivo produktion af proteiner med en formulering, der omfatter leucin - Google Patents
Stimulering af in vivo produktion af proteiner med en formulering, der omfatter leucinInfo
- Publication number
- DK1455603T3 DK1455603T3 DK03782981T DK03782981T DK1455603T3 DK 1455603 T3 DK1455603 T3 DK 1455603T3 DK 03782981 T DK03782981 T DK 03782981T DK 03782981 T DK03782981 T DK 03782981T DK 1455603 T3 DK1455603 T3 DK 1455603T3
- Authority
- DK
- Denmark
- Prior art keywords
- formulation
- leucine
- stimulation
- proteins
- vivo production
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 title abstract 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000001727 in vivo Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000000638 stimulation Effects 0.000 title 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 235000015872 dietary supplement Nutrition 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000008092 positive effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Fodder In General (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/325,711 US7288570B2 (en) | 2002-12-20 | 2002-12-20 | Stimulation of in vivo production of proteins |
| PCT/NL2003/000892 WO2004056208A1 (en) | 2002-12-20 | 2003-12-15 | Stimulation of in vivo production of proteins with formulation comprising leucine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1455603T3 true DK1455603T3 (da) | 2007-02-05 |
Family
ID=32593858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03782981T DK1455603T3 (da) | 2002-12-20 | 2003-12-15 | Stimulering af in vivo produktion af proteiner med en formulering, der omfatter leucin |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7288570B2 (https=) |
| EP (1) | EP1455603B1 (https=) |
| JP (1) | JP2006510711A (https=) |
| CN (1) | CN100353866C (https=) |
| AT (1) | ATE341226T1 (https=) |
| AU (1) | AU2003290447B2 (https=) |
| CA (1) | CA2510760C (https=) |
| DE (1) | DE60308810T2 (https=) |
| DK (1) | DK1455603T3 (https=) |
| ES (1) | ES2274299T3 (https=) |
| WO (1) | WO2004056208A1 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4970694B2 (ja) * | 2002-12-02 | 2012-07-11 | 株式会社明治 | 持続性筋肉疲労改善剤 |
| US7288570B2 (en) * | 2002-12-20 | 2007-10-30 | Nutricia N.V. | Stimulation of in vivo production of proteins |
| BRPI0606687A2 (pt) * | 2005-01-18 | 2009-07-14 | Dsm Ip Assets Bv | composições nutracêuticas |
| EP1774973A1 (en) * | 2005-10-12 | 2007-04-18 | Nutricia N.V. | Leucine rich composition |
| EP1945044B1 (en) * | 2005-10-26 | 2009-04-15 | Hill's Pet Nutrition Inc. | Compositions for increasing lean muscle mass and/or reducing fat gain |
| ES2302463B1 (es) * | 2006-12-29 | 2009-06-05 | Madaus, S.A. | "composicion a base de fibra de cacao". |
| US8597677B2 (en) | 2007-02-23 | 2013-12-03 | Hill's Pet Nutrition, Inc. | Compositions and methods for controlling the weight of animals |
| EP2098124A1 (en) * | 2008-03-03 | 2009-09-09 | Nestec S.A. | Carbohydrate gel |
| ES2371789T3 (es) * | 2008-03-03 | 2012-01-10 | Nestec S.A. | Producto alimenticio gelificado con una elevada eficacia en aporte de hidratos de carbono. |
| EP2098126A1 (en) * | 2008-03-03 | 2009-09-09 | Nestec S.A. | Carbohydrate Bar |
| WO2010002242A1 (en) * | 2008-07-02 | 2010-01-07 | N.V. Nutricia | Nutritional composition for improving muscle function and daily activity |
| EP2298090B1 (en) | 2009-08-26 | 2016-01-13 | Jeffrey M. Golini | Pharmaceutical or nutraceutical composition |
| EP2327316B1 (en) * | 2009-11-29 | 2016-11-16 | Premier Nutrition Corporation | Method of enhancing muscle protein synthesis |
| ES2441365T3 (es) * | 2009-11-29 | 2014-02-04 | Nestec S.A. | Protocolos de dosificación para incrementar la síntesis de proteínas en un individuo activo |
| WO2011078654A1 (en) * | 2009-12-24 | 2011-06-30 | N.V. Nutricia | Low-caloric high-protein nutritional composition for the stimulation of muscle protein synthesis |
| US20120296403A1 (en) | 2010-02-10 | 2012-11-22 | Novartis Ag | Methods and compounds for muscle growth |
| AU2011224427B2 (en) * | 2010-03-12 | 2014-07-31 | Société des Produits Nestlé S.A. | Compositions for masking the flavor of nutrients and methods for making same |
| WO2012005568A1 (en) * | 2010-07-07 | 2012-01-12 | N.V. Nutricia | Nutritional composition for the stimulation of muscle protein synthesis |
| RU2631597C2 (ru) | 2011-07-15 | 2017-09-25 | Нусерт Сайенсиз, Инк. | Композиции и способы модулирования метаболических путей |
| US9198454B2 (en) | 2012-03-08 | 2015-12-01 | Nusirt Sciences, Inc. | Compositions, methods, and kits for regulating energy metabolism |
| US9700071B2 (en) | 2012-03-26 | 2017-07-11 | Axcella Health Inc. | Nutritive fragments, proteins and methods |
| EP2831100A4 (en) | 2012-03-26 | 2016-02-10 | Pronutria Inc | NUTRIENT PROTEINS AND METHOD |
| EP2831098A4 (en) | 2012-03-26 | 2016-12-07 | Axcella Health Inc | LOADED NUTRIENT PROTEINS AND METHODS |
| RU2634407C2 (ru) | 2012-03-26 | 2017-10-26 | Эксселла Хелт Инк. | Фрагменты пищевых белков и способы их применения |
| SG10201709195TA (en) | 2012-11-13 | 2017-12-28 | Nusirt Sciences Inc | Compositions and methods for increasing energy metabolism |
| CN105228627B (zh) | 2013-03-15 | 2018-07-13 | 纽斯尔特科学公司 | 亮氨酸和烟酸降低脂质水平 |
| US9597367B2 (en) | 2013-04-19 | 2017-03-21 | Bioventures, Llc | Methods for improving muscle and heart function |
| CA2914811C (en) * | 2013-06-10 | 2020-10-27 | N.V. Nutricia | Muscle preservation in overweight or obese adult during weight loss program |
| RU2016110800A (ru) | 2013-09-25 | 2017-10-30 | Пронутриа Биосайенсис, Инк. | Составы и композиции для поддержания и увеличения мышечной массы, силы и результативности, и способы их производства и использования |
| KR20160119863A (ko) | 2014-02-27 | 2016-10-14 | 뉴서트 사이언시스, 인크. | 간 지방증의 감소 또는 예방을 위한 조성물 및 방법 |
| CN107148272A (zh) | 2014-08-29 | 2017-09-08 | 吡哆胺研究有限公司 | 通过组合吡哆胺化合物和硫胺化合物形成的药物组合物 |
| US10188135B2 (en) * | 2015-11-04 | 2019-01-29 | Stokley-Van Camp, Inc. | Method for inducing satiety |
| RU2601406C1 (ru) * | 2015-11-17 | 2016-11-10 | Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Медицинский Университет Имени В.И. Разумовского" Министерства Здравоохранения Российской Федерации | Средство, обладающее антикахексическим, противоопухолевым свойствами и снижающее уровень эндогенной интоксикации |
| JP6105111B1 (ja) * | 2016-03-02 | 2017-03-29 | 国立大学法人東北大学 | 自閉スペクトラム症改善用組成物 |
| JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
| MX2020001765A (es) | 2017-08-14 | 2020-07-29 | Axcella Health Inc | Composiciones de aminoacidos para el tratamiento de enfermedad hepatica. |
| CH714189A1 (de) * | 2017-09-25 | 2019-03-29 | Omanda Ag | Verfahren zur Herstellung von L-Leucin und Molkenprotein L-Leucin zur Nahrungsanreicherung und dessen Anwendung. |
| EP3703516A4 (en) | 2017-11-02 | 2021-08-18 | BioVentures, LLC | USE OF AMINO ACID SUPPLEMENTATION FOR IMPROVED MUSCLE PROTEIN SYNTHESIS |
| CN112839643A (zh) | 2018-06-20 | 2021-05-25 | 胺细拉健康公司 | 用于治疗肌肉中脂肪浸润的组合物及方法 |
| CH715997A1 (de) * | 2019-03-25 | 2020-09-30 | Omanda Ag | Proteingetränk und Darreichungseinheit zur Verabreichung von mit L-Leucin-angereicherten Molkenproteinkomponenten als Nahrungsanreicherung und dessen Herstellung. |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928445A (en) * | 1973-12-26 | 1975-12-23 | Allied Chem | Synthesis of 2-halo-5-cyano alkyl valerate |
| JPS6049764A (ja) * | 1983-08-29 | 1985-03-19 | Ajinomoto Co Inc | 食品組成物 |
| JPS60186261A (ja) * | 1984-03-06 | 1985-09-21 | Ajinomoto Co Inc | 固体状食品組成物 |
| US4687782A (en) | 1984-12-10 | 1987-08-18 | Nutri-Fuels Systems, Inc. | Nutritional composition for enhancing skeletal muscle adaptation to exercise training |
| US5639731A (en) * | 1987-05-22 | 1997-06-17 | Pripps Bryggerier Ab | Amino acids for the preparation of a beverage |
| CA1333471C (en) * | 1988-04-29 | 1994-12-13 | Gustavo Bounous | Whey protein concentrate as food supplement |
| US5242697A (en) | 1990-10-26 | 1993-09-07 | Maurizio Luca | Method of preparing nutrified food products |
| JP3622271B2 (ja) | 1995-07-11 | 2005-02-23 | 味の素株式会社 | 馬用栄養組成物 |
| US5817329A (en) * | 1997-02-28 | 1998-10-06 | Gardiner; Paul T. | Nutritional supplement for increased muscle size and strength for body builders |
| IT1291127B1 (it) | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
| DE29707308U1 (de) | 1997-04-23 | 1997-06-26 | Kunz, Armin, 66450 Bexbach | Präparat zur Muskelerhaltung bzw. zur Förderung des Muskelaufbaus |
| US6051236A (en) * | 1998-11-12 | 2000-04-18 | Pacifichealth Laboratories, Inc. | Composition for optimizing muscle performance during exercise |
| US6221418B1 (en) * | 1999-03-25 | 2001-04-24 | Focused Foods, Inc. | High protein edible composition and method of preparing the same |
| US6241996B1 (en) * | 1999-04-09 | 2001-06-05 | Novartis Nutrition Ag | Liquid soy nutritional products |
| EP1112693B1 (en) | 1999-12-30 | 2006-03-22 | Kerry Group Services Ltd | Composition comprising carbohydrate and peptide material and its use as an energy supplement after or during physical exercise or as a metabolic nutrient for oral consumption |
| US6521591B1 (en) * | 2000-02-10 | 2003-02-18 | N.V. Nutricia | Pharmaceutical composition for muscular anabolism |
| US6420342B1 (en) * | 2000-05-08 | 2002-07-16 | N.V. Nutricia | Nutritional preparation comprising ribose and medical use thereof |
| US6706295B2 (en) * | 2000-09-29 | 2004-03-16 | The Procter & Gamble Co. | Compositions comprising arabinogalactan and a defined protein component |
| GB0110288D0 (en) | 2001-04-26 | 2001-06-20 | Novartis Nutrition Ag | Composition and treatment method |
| US7288570B2 (en) * | 2002-12-20 | 2007-10-30 | Nutricia N.V. | Stimulation of in vivo production of proteins |
-
2002
- 2002-12-20 US US10/325,711 patent/US7288570B2/en not_active Expired - Lifetime
-
2003
- 2003-12-15 EP EP03782981A patent/EP1455603B1/en not_active Expired - Lifetime
- 2003-12-15 CA CA2510760A patent/CA2510760C/en not_active Expired - Fee Related
- 2003-12-15 WO PCT/NL2003/000892 patent/WO2004056208A1/en not_active Ceased
- 2003-12-15 AT AT03782981T patent/ATE341226T1/de active
- 2003-12-15 JP JP2004562109A patent/JP2006510711A/ja active Pending
- 2003-12-15 ES ES03782981T patent/ES2274299T3/es not_active Expired - Lifetime
- 2003-12-15 AU AU2003290447A patent/AU2003290447B2/en not_active Ceased
- 2003-12-15 DE DE60308810T patent/DE60308810T2/de not_active Expired - Lifetime
- 2003-12-15 CN CNB2003801098651A patent/CN100353866C/zh not_active Expired - Lifetime
- 2003-12-15 DK DK03782981T patent/DK1455603T3/da active
-
2007
- 2007-10-16 US US11/872,804 patent/US20080161398A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7288570B2 (en) | 2007-10-30 |
| CN100353866C (zh) | 2007-12-12 |
| HK1065447A1 (en) | 2005-02-25 |
| WO2004056208A1 (en) | 2004-07-08 |
| US20040122097A1 (en) | 2004-06-24 |
| US20080161398A1 (en) | 2008-07-03 |
| EP1455603A1 (en) | 2004-09-15 |
| DE60308810D1 (de) | 2006-11-16 |
| CA2510760C (en) | 2011-09-20 |
| AU2003290447A1 (en) | 2004-07-14 |
| AU2003290447A2 (en) | 2005-08-25 |
| ATE341226T1 (de) | 2006-10-15 |
| DE60308810T2 (de) | 2007-08-02 |
| CN1753625A (zh) | 2006-03-29 |
| EP1455603B1 (en) | 2006-10-04 |
| JP2006510711A (ja) | 2006-03-30 |
| CA2510760A1 (en) | 2004-07-08 |
| ES2274299T3 (es) | 2007-05-16 |
| AU2003290447B2 (en) | 2007-10-04 |
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