AU2003290447B2 - Stimulation of in vivo production of proteins with formulation comprising leucine - Google Patents

Stimulation of in vivo production of proteins with formulation comprising leucine Download PDF

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Publication number
AU2003290447B2
AU2003290447B2 AU2003290447A AU2003290447A AU2003290447B2 AU 2003290447 B2 AU2003290447 B2 AU 2003290447B2 AU 2003290447 A AU2003290447 A AU 2003290447A AU 2003290447 A AU2003290447 A AU 2003290447A AU 2003290447 B2 AU2003290447 B2 AU 2003290447B2
Authority
AU
Australia
Prior art keywords
formulation according
leucine
formulation
grams
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003290447A
Other languages
English (en)
Other versions
AU2003290447A1 (en
AU2003290447A2 (en
Inventor
Rudolf Leonardus Lodewijk Smeets
George Verlaan
Robert Reese Wolfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nutricia NV
Original Assignee
Nutricia NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutricia NV filed Critical Nutricia NV
Publication of AU2003290447A1 publication Critical patent/AU2003290447A1/en
Publication of AU2003290447A2 publication Critical patent/AU2003290447A2/en
Application granted granted Critical
Publication of AU2003290447B2 publication Critical patent/AU2003290447B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2003290447A 2002-12-20 2003-12-15 Stimulation of in vivo production of proteins with formulation comprising leucine Ceased AU2003290447B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/325,711 2002-12-20
US10/325,711 US7288570B2 (en) 2002-12-20 2002-12-20 Stimulation of in vivo production of proteins
PCT/NL2003/000892 WO2004056208A1 (en) 2002-12-20 2003-12-15 Stimulation of in vivo production of proteins with formulation comprising leucine

Publications (3)

Publication Number Publication Date
AU2003290447A1 AU2003290447A1 (en) 2004-07-14
AU2003290447A2 AU2003290447A2 (en) 2005-08-25
AU2003290447B2 true AU2003290447B2 (en) 2007-10-04

Family

ID=32593858

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003290447A Ceased AU2003290447B2 (en) 2002-12-20 2003-12-15 Stimulation of in vivo production of proteins with formulation comprising leucine

Country Status (11)

Country Link
US (2) US7288570B2 (https=)
EP (1) EP1455603B1 (https=)
JP (1) JP2006510711A (https=)
CN (1) CN100353866C (https=)
AT (1) ATE341226T1 (https=)
AU (1) AU2003290447B2 (https=)
CA (1) CA2510760C (https=)
DE (1) DE60308810T2 (https=)
DK (1) DK1455603T3 (https=)
ES (1) ES2274299T3 (https=)
WO (1) WO2004056208A1 (https=)

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JP4970694B2 (ja) * 2002-12-02 2012-07-11 株式会社明治 持続性筋肉疲労改善剤
US7288570B2 (en) * 2002-12-20 2007-10-30 Nutricia N.V. Stimulation of in vivo production of proteins
BRPI0606687A2 (pt) * 2005-01-18 2009-07-14 Dsm Ip Assets Bv composições nutracêuticas
EP1774973A1 (en) * 2005-10-12 2007-04-18 Nutricia N.V. Leucine rich composition
EP1945044B1 (en) * 2005-10-26 2009-04-15 Hill's Pet Nutrition Inc. Compositions for increasing lean muscle mass and/or reducing fat gain
ES2302463B1 (es) * 2006-12-29 2009-06-05 Madaus, S.A. "composicion a base de fibra de cacao".
US8597677B2 (en) 2007-02-23 2013-12-03 Hill's Pet Nutrition, Inc. Compositions and methods for controlling the weight of animals
EP2098124A1 (en) * 2008-03-03 2009-09-09 Nestec S.A. Carbohydrate gel
ES2371789T3 (es) * 2008-03-03 2012-01-10 Nestec S.A. Producto alimenticio gelificado con una elevada eficacia en aporte de hidratos de carbono.
EP2098126A1 (en) * 2008-03-03 2009-09-09 Nestec S.A. Carbohydrate Bar
WO2010002242A1 (en) * 2008-07-02 2010-01-07 N.V. Nutricia Nutritional composition for improving muscle function and daily activity
EP2298090B1 (en) 2009-08-26 2016-01-13 Jeffrey M. Golini Pharmaceutical or nutraceutical composition
EP2327316B1 (en) * 2009-11-29 2016-11-16 Premier Nutrition Corporation Method of enhancing muscle protein synthesis
ES2441365T3 (es) * 2009-11-29 2014-02-04 Nestec S.A. Protocolos de dosificación para incrementar la síntesis de proteínas en un individuo activo
WO2011078654A1 (en) * 2009-12-24 2011-06-30 N.V. Nutricia Low-caloric high-protein nutritional composition for the stimulation of muscle protein synthesis
US20120296403A1 (en) 2010-02-10 2012-11-22 Novartis Ag Methods and compounds for muscle growth
AU2011224427B2 (en) * 2010-03-12 2014-07-31 Société des Produits Nestlé S.A. Compositions for masking the flavor of nutrients and methods for making same
WO2012005568A1 (en) * 2010-07-07 2012-01-12 N.V. Nutricia Nutritional composition for the stimulation of muscle protein synthesis
RU2631597C2 (ru) 2011-07-15 2017-09-25 Нусерт Сайенсиз, Инк. Композиции и способы модулирования метаболических путей
US9198454B2 (en) 2012-03-08 2015-12-01 Nusirt Sciences, Inc. Compositions, methods, and kits for regulating energy metabolism
US9700071B2 (en) 2012-03-26 2017-07-11 Axcella Health Inc. Nutritive fragments, proteins and methods
EP2831100A4 (en) 2012-03-26 2016-02-10 Pronutria Inc NUTRIENT PROTEINS AND METHOD
EP2831098A4 (en) 2012-03-26 2016-12-07 Axcella Health Inc LOADED NUTRIENT PROTEINS AND METHODS
RU2634407C2 (ru) 2012-03-26 2017-10-26 Эксселла Хелт Инк. Фрагменты пищевых белков и способы их применения
SG10201709195TA (en) 2012-11-13 2017-12-28 Nusirt Sciences Inc Compositions and methods for increasing energy metabolism
CN105228627B (zh) 2013-03-15 2018-07-13 纽斯尔特科学公司 亮氨酸和烟酸降低脂质水平
US9597367B2 (en) 2013-04-19 2017-03-21 Bioventures, Llc Methods for improving muscle and heart function
CA2914811C (en) * 2013-06-10 2020-10-27 N.V. Nutricia Muscle preservation in overweight or obese adult during weight loss program
RU2016110800A (ru) 2013-09-25 2017-10-30 Пронутриа Биосайенсис, Инк. Составы и композиции для поддержания и увеличения мышечной массы, силы и результативности, и способы их производства и использования
KR20160119863A (ko) 2014-02-27 2016-10-14 뉴서트 사이언시스, 인크. 간 지방증의 감소 또는 예방을 위한 조성물 및 방법
CN107148272A (zh) 2014-08-29 2017-09-08 吡哆胺研究有限公司 通过组合吡哆胺化合物和硫胺化合物形成的药物组合物
US10188135B2 (en) * 2015-11-04 2019-01-29 Stokley-Van Camp, Inc. Method for inducing satiety
RU2601406C1 (ru) * 2015-11-17 2016-11-10 Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Медицинский Университет Имени В.И. Разумовского" Министерства Здравоохранения Российской Федерации Средство, обладающее антикахексическим, противоопухолевым свойствами и снижающее уровень эндогенной интоксикации
JP6105111B1 (ja) * 2016-03-02 2017-03-29 国立大学法人東北大学 自閉スペクトラム症改善用組成物
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
MX2020001765A (es) 2017-08-14 2020-07-29 Axcella Health Inc Composiciones de aminoacidos para el tratamiento de enfermedad hepatica.
CH714189A1 (de) * 2017-09-25 2019-03-29 Omanda Ag Verfahren zur Herstellung von L-Leucin und Molkenprotein L-Leucin zur Nahrungsanreicherung und dessen Anwendung.
EP3703516A4 (en) 2017-11-02 2021-08-18 BioVentures, LLC USE OF AMINO ACID SUPPLEMENTATION FOR IMPROVED MUSCLE PROTEIN SYNTHESIS
CN112839643A (zh) 2018-06-20 2021-05-25 胺细拉健康公司 用于治疗肌肉中脂肪浸润的组合物及方法
CH715997A1 (de) * 2019-03-25 2020-09-30 Omanda Ag Proteingetränk und Darreichungseinheit zur Verabreichung von mit L-Leucin-angereicherten Molkenproteinkomponenten als Nahrungsanreicherung und dessen Herstellung.

Citations (1)

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Publication number Priority date Publication date Assignee Title
EP1455603A1 (en) * 2002-12-20 2004-09-15 Nutricia N.V. Stimulation of in vivo production of proteins with formulation comprising leucine

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Also Published As

Publication number Publication date
US7288570B2 (en) 2007-10-30
CN100353866C (zh) 2007-12-12
DK1455603T3 (da) 2007-02-05
HK1065447A1 (en) 2005-02-25
WO2004056208A1 (en) 2004-07-08
US20040122097A1 (en) 2004-06-24
US20080161398A1 (en) 2008-07-03
EP1455603A1 (en) 2004-09-15
DE60308810D1 (de) 2006-11-16
CA2510760C (en) 2011-09-20
AU2003290447A1 (en) 2004-07-14
AU2003290447A2 (en) 2005-08-25
ATE341226T1 (de) 2006-10-15
DE60308810T2 (de) 2007-08-02
CN1753625A (zh) 2006-03-29
EP1455603B1 (en) 2006-10-04
JP2006510711A (ja) 2006-03-30
CA2510760A1 (en) 2004-07-08
ES2274299T3 (es) 2007-05-16

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 07 JUL 2005

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired