DK1442006T3 - Fremstilling af amfetaminer fra phenylpropanolaminer - Google Patents

Fremstilling af amfetaminer fra phenylpropanolaminer

Info

Publication number
DK1442006T3
DK1442006T3 DK02802245T DK02802245T DK1442006T3 DK 1442006 T3 DK1442006 T3 DK 1442006T3 DK 02802245 T DK02802245 T DK 02802245T DK 02802245 T DK02802245 T DK 02802245T DK 1442006 T3 DK1442006 T3 DK 1442006T3
Authority
DK
Denmark
Prior art keywords
formula
alkyl group
group
lower alkyl
phenylpropanolamine salt
Prior art date
Application number
DK02802245T
Other languages
English (en)
Inventor
Robert F Boswell
Young S Lo
Original Assignee
Boehringer Ingelheim Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Chemicals filed Critical Boehringer Ingelheim Chemicals
Application granted granted Critical
Publication of DK1442006T3 publication Critical patent/DK1442006T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK02802245T 2001-10-29 2002-10-28 Fremstilling af amfetaminer fra phenylpropanolaminer DK1442006T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/020,488 US6399828B1 (en) 2001-10-29 2001-10-29 Preparation of amphetamines from phenylpropanolamines

Publications (1)

Publication Number Publication Date
DK1442006T3 true DK1442006T3 (da) 2005-12-12

Family

ID=21798883

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02802245T DK1442006T3 (da) 2001-10-29 2002-10-28 Fremstilling af amfetaminer fra phenylpropanolaminer

Country Status (11)

Country Link
US (1) US6399828B1 (da)
EP (1) EP1442006B1 (da)
JP (1) JP2005507936A (da)
AT (1) ATE302747T1 (da)
AU (1) AU2002356860A1 (da)
CA (1) CA2462916A1 (da)
DE (1) DE60205769T2 (da)
DK (1) DK1442006T3 (da)
ES (1) ES2248640T3 (da)
PT (1) PT1442006E (da)
WO (1) WO2003037843A2 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004251647B2 (en) * 2003-05-29 2010-01-14 Takeda Pharmaceutical Company Limited Abuse resistant amphetamine compounds
ATE407112T1 (de) * 2004-12-22 2008-09-15 Emmellen Biotech Pharmaceutica Verfahren zur herstellung von r-(-)-n, alpha- dimethylphenethylamin (levmetamphetamin) oder s- (+)-n, alpha-dimethylphenethylamin (metamphetamin) aus d-ephedrin bzw. l-ephedrin
WO2006073547A1 (en) * 2005-01-06 2006-07-13 Mallinckrodt Inc. Process for preparing benzylated amines
TWI401237B (zh) * 2006-07-24 2013-07-11 ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備
US7705184B2 (en) * 2008-05-20 2010-04-27 Cambrex Charles City, Inc. Method of making amphetamine
US20100125146A1 (en) * 2008-11-19 2010-05-20 Johnson Matthey Public Limited Company Method for making pharmaceutical compounds
WO2010148305A1 (en) * 2009-06-19 2010-12-23 Cambrex Charles City, Inc. Methods and compositions for preparation of amphetamine conjugates and salts thereof
JP5094832B2 (ja) * 2009-12-25 2012-12-12 日東電工株式会社 粘着剤組成物および粘着シート
JP5657913B2 (ja) * 2010-05-10 2015-01-21 中部電力株式会社 ナノコンポジット半導体光触媒材料とメタノール水溶液を用いた水素製造手法
US8779191B2 (en) 2010-12-20 2014-07-15 Cambrex Charles City, Inc. Methods and compositions for preparing lisdexamfetamine and salts thereof
US9321794B2 (en) 2013-12-31 2016-04-26 Chemapotheca, Llc Synthesis of racemic amphetamine derivatives by cuprate addition reaction with aziridine phosphoramidate compounds
US11123310B2 (en) 2017-02-24 2021-09-21 Pharmapotheca, Llc Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms
US9278904B2 (en) 2013-12-31 2016-03-08 Chemapotheca, Llc Synthesis of chiral amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds
US10544434B2 (en) 2015-06-29 2020-01-28 Noramco, Inc. Process for the preparation of lisdexamfetamine and related derivatives
CA3015500A1 (en) 2016-02-24 2017-08-31 Chemapotheca, Llc Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
DE112020001032T5 (de) 2019-03-02 2021-12-09 Chemapotheca, Llc Verfahren zur Herstellung von Levoamphetamin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2802828A (en) * 1957-08-13 New derivatives of hydroxylated
DE2817494A1 (de) * 1977-05-03 1978-11-09 Continental Pharma Aminoalkohol-derivat
DE19859684A1 (de) * 1998-12-23 2000-06-29 Bayer Ag Verfahren zur Herstellung von Fluor enthaltenden Phenethylaminen sowie neue, Fluor enthalende beta-Iminovinyl- und beta-Iminoethylbenzole

Also Published As

Publication number Publication date
CA2462916A1 (en) 2003-05-08
ATE302747T1 (de) 2005-09-15
DE60205769D1 (de) 2005-09-29
EP1442006A2 (en) 2004-08-04
DE60205769T2 (de) 2006-06-08
WO2003037843A2 (en) 2003-05-08
PT1442006E (pt) 2005-11-30
EP1442006B1 (en) 2005-08-24
US6399828B1 (en) 2002-06-04
AU2002356860A1 (en) 2003-05-12
WO2003037843A3 (en) 2003-10-30
ES2248640T3 (es) 2006-03-16
JP2005507936A (ja) 2005-03-24

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