DK142200B - Analogifremgangsmåde til fremstilling af 14-substituerede vincanderivater eller syreadditionssalte eller kvaternære salte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 14-substituerede vincanderivater eller syreadditionssalte eller kvaternære salte deraf. Download PDF

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Publication number
DK142200B
DK142200B DK393076AA DK393076A DK142200B DK 142200 B DK142200 B DK 142200B DK 393076A A DK393076A A DK 393076AA DK 393076 A DK393076 A DK 393076A DK 142200 B DK142200 B DK 142200B
Authority
DK
Denmark
Prior art keywords
acid
vincane
solution
group
reaction
Prior art date
Application number
DK393076AA
Other languages
Danish (da)
English (en)
Other versions
DK142200C (de
DK393076A (de
Inventor
Laszlo Szporny
Egon Karpati
Jozsef Koekoesi
Otto Clauder
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK393076A publication Critical patent/DK393076A/da
Publication of DK142200B publication Critical patent/DK142200B/da
Application granted granted Critical
Publication of DK142200C publication Critical patent/DK142200C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK393076AA 1975-09-01 1976-08-31 Analogifremgangsmåde til fremstilling af 14-substituerede vincanderivater eller syreadditionssalte eller kvaternære salte deraf. DK142200B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HURI000577 1975-09-01
HU75RI00000577A HU171663B (hu) 1975-09-01 1975-09-01 Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana

Publications (3)

Publication Number Publication Date
DK393076A DK393076A (de) 1977-03-02
DK142200B true DK142200B (da) 1980-09-22
DK142200C DK142200C (de) 1981-02-23

Family

ID=11000986

Family Applications (1)

Application Number Title Priority Date Filing Date
DK393076AA DK142200B (da) 1975-09-01 1976-08-31 Analogifremgangsmåde til fremstilling af 14-substituerede vincanderivater eller syreadditionssalte eller kvaternære salte deraf.

Country Status (14)

Country Link
US (1) US4120858A (de)
JP (1) JPS5236699A (de)
AT (1) AT352298B (de)
BE (1) BE845700A (de)
CH (2) CH628896A5 (de)
DD (1) DD125944A5 (de)
DE (1) DE2639139A1 (de)
DK (1) DK142200B (de)
FR (1) FR2321885A1 (de)
GB (1) GB1563396A (de)
HU (1) HU171663B (de)
NL (1) NL7609662A (de)
PL (1) PL115848B1 (de)
SE (1) SE427182B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5732281A (en) * 1980-08-06 1982-02-20 Sumitomo Chem Co Ltd Nitrogen-containing polycyclic compound and its preparation
FR2514357A1 (fr) * 1981-10-08 1983-04-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine eventuellement substitues sur le cycle e, procede de preparation et application comme medicaments
JPS6019650A (ja) * 1983-07-13 1985-01-31 Koyo Jidoki テ−プ状ラベルの送り装置
HU198207B (en) * 1985-04-19 1989-08-28 Richter Gedeon Vegyeszet Process for production of derivatives of eburnamenin and medical compositions containing them
HU207074B (en) * 1990-12-07 1993-03-01 Richter Gedeon Vegyeszet Process for producing optically active cis and trans 14-(n-substituted-aminomethyl)-eburnane derivatives and pharmaceutical compositions comprising same
HU209678B (en) * 1992-06-09 1994-10-28 Richter Gedeon Vegyeszet Process for producing biologically active eburnamenin-14-carbonyl-amino derivatives and pharmaceutical compositions containing them

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455936A (en) * 1967-04-18 1969-07-15 Smithkline Corp Substituted indolo(2,3-a)quinolizinium salts
FR2035784A1 (en) * 1969-03-27 1970-12-24 Olivier Louisette Vincamine derivs with therapeutic propert- - ies
FR2121360B1 (de) * 1971-01-06 1974-03-22 Roussel Uclaf
FR2190433A1 (en) * 1972-06-30 1974-02-01 Synthelabo O-alkylvincamols and salts - with vasodilator, hypotensive, antifibrill-atory and spasmolytic activity
FR2259612B1 (de) * 1974-01-31 1977-09-09 Synthelabo
FR2275211A2 (fr) * 1974-06-19 1976-01-16 Synthelabo Nouveaux amides de l'acide dihydroapovincaminique, leurs sels, leur preparation et les medicaments qui en contiennent
FI751840A (de) * 1974-09-24 1976-03-25 Synthelabo

Also Published As

Publication number Publication date
JPS5439400B2 (de) 1979-11-27
DE2639139A1 (de) 1977-03-03
SE427182B (sv) 1983-03-14
GB1563396A (en) 1980-03-26
DK142200C (de) 1981-02-23
FR2321885B1 (de) 1980-07-04
DK393076A (de) 1977-03-02
CH634573A5 (de) 1983-02-15
NL7609662A (nl) 1977-03-03
HU171663B (hu) 1978-02-28
AT352298B (de) 1979-09-10
DD125944A5 (de) 1977-06-01
PL115848B1 (en) 1981-05-30
JPS5236699A (en) 1977-03-22
FR2321885A1 (fr) 1977-03-25
US4120858A (en) 1978-10-17
CH628896A5 (de) 1982-03-31
BE845700A (fr) 1976-12-16
SE7609424L (sv) 1977-03-02
ATA629576A (de) 1979-02-15

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