DK1394272T3 - Fremgangsmåde til påvisning af ki-ras-mutationer - Google Patents

Fremgangsmåde til påvisning af ki-ras-mutationer

Info

Publication number
DK1394272T3
DK1394272T3 DK03020560T DK03020560T DK1394272T3 DK 1394272 T3 DK1394272 T3 DK 1394272T3 DK 03020560 T DK03020560 T DK 03020560T DK 03020560 T DK03020560 T DK 03020560T DK 1394272 T3 DK1394272 T3 DK 1394272T3
Authority
DK
Denmark
Prior art keywords
detecting
ras mutations
pcr
tissue
allele specific
Prior art date
Application number
DK03020560T
Other languages
Danish (da)
English (en)
Inventor
Arve Ulrik
Jan Jacob Koornstra
Dagfinn Ogreid
Original Assignee
Nordiag As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordiag As filed Critical Nordiag As
Application granted granted Critical
Publication of DK1394272T3 publication Critical patent/DK1394272T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Holo Graphy (AREA)
  • Saccharide Compounds (AREA)
DK03020560T 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af ki-ras-mutationer DK1394272T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO954667A NO954667D0 (no) 1995-11-17 1995-11-17 Fremgangsmåte til deteksjon av Ki-ras mutasjoner
EP96939373A EP0868529B1 (en) 1995-11-17 1996-11-15 Method for detection of ki-ras mutations and kit to perform it

Publications (1)

Publication Number Publication Date
DK1394272T3 true DK1394272T3 (da) 2006-07-03

Family

ID=19898772

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96939373T DK0868529T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af Ki-ras-mutationer og et kit til udførelse deraf
DK03020560T DK1394272T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af ki-ras-mutationer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK96939373T DK0868529T3 (da) 1995-11-17 1996-11-15 Fremgangsmåde til påvisning af Ki-ras-mutationer og et kit til udførelse deraf

Country Status (12)

Country Link
US (1) US6440661B1 (OSRAM)
EP (2) EP0868529B1 (OSRAM)
JP (1) JP2000500346A (OSRAM)
AT (2) ATE318934T1 (OSRAM)
AU (1) AU723980C (OSRAM)
DE (2) DE69630234T2 (OSRAM)
DK (2) DK0868529T3 (OSRAM)
ES (2) ES2208766T3 (OSRAM)
NO (2) NO954667D0 (OSRAM)
NZ (1) NZ322619A (OSRAM)
PT (2) PT1394272E (OSRAM)
WO (1) WO1997019191A1 (OSRAM)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9715034D0 (en) * 1997-07-18 1997-09-24 Zeneca Ltd Assay
JP4794052B2 (ja) * 1999-04-09 2011-10-12 ジェンザイム・コーポレーション 癌の指標である核酸を検出するための方法
US6531302B1 (en) * 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
ATE458831T1 (de) 1999-12-07 2010-03-15 Exact Sciences Corp Verfahren zum nachweis von lungenneoplasmen in fäkalen proben
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
EP2351853A1 (en) * 2000-06-06 2011-08-03 Life Technologies Corporation Method and devices for multiplexing amplification reactions
US6605451B1 (en) * 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
EP3000899A1 (en) 2002-12-04 2016-03-30 Applied Biosystems, LLC Multiplex amplification of polynucleotides
WO2005113769A1 (en) * 2004-05-14 2005-12-01 Exact Sciences Corporation Method for stabilizing biological samples for nucleic acid analysis
US20070134709A1 (en) * 2005-12-14 2007-06-14 Xiping Xu Usages of MTHFR gene polymorphisms in predicting homocysteine level, disease risk, and treatment effects and related methods and kit
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
US8768629B2 (en) 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
BRPI0711011A2 (pt) 2006-05-18 2011-08-23 Molecular Profiling Inst Inc método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
BRPI0921043A2 (pt) 2008-11-12 2018-08-07 Caris Life Sciences Luxembourg Holdings métodos e sistemas para usar exossomas para determinar fenótipos
EP2519644A4 (en) * 2009-12-31 2013-11-06 Van Andel Res Inst METHOD FOR THE DIAGNOSIS OF THE MALIGNANT POTENTIAL OF CYSTIC PANCREASLESIONS
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
KR20130043104A (ko) 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 질병용 순환 생물학적 지표들
WO2012040387A1 (en) 2010-09-24 2012-03-29 The Board Of Trustees Of The Leland Stanford Junior University Direct capture, amplification and sequencing of target dna using immobilized primers
GB201107466D0 (en) 2011-05-05 2011-06-15 Loktionov Alexandre Device and method for non-invasive collection of colorectal mucocellular layer and disease detection
CN102796811B (zh) * 2011-05-26 2013-12-18 上海赛安生物医药科技有限公司 检测kras突变的试剂及方法
BR112013032629A2 (pt) 2011-06-19 2017-08-01 Abogen Inc dispositivos, soluções e métodos para coletamento de amostra
AU2012339835B2 (en) * 2011-11-17 2016-01-28 The Johns Hopkins University Differential identification of pancreatic cysts
JP2016507723A (ja) * 2012-11-30 2016-03-10 アプライド・プロテオミクス，インコーポレイテッド 結腸腫瘍の存在またはリスクの評価方法
DK3114225T3 (da) 2014-03-07 2021-07-26 Dna Genotek Inc Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver
US9689874B2 (en) 2015-04-10 2017-06-27 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US10753936B2 (en) 2016-07-22 2020-08-25 Van Andel Research Institute Method of detecting the level of a glycan
MX2020014243A (es) 2018-06-19 2021-05-12 Biontech Us Inc Neoantigenos y usos de los mismos.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4871838A (en) * 1985-07-23 1989-10-03 The Board Of Rijks Universiteit Leiden Probes and methods for detecting activated ras oncogenes
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
JP3633932B2 (ja) 1992-04-01 2005-03-30 ザ ジョーンズ ホプキンズ ユニバーシティー スクール オブ メディシン 糞便試料から単離した哺乳類の核酸を検出する方法、およびその検出用試薬
EP0655090B1 (en) * 1992-04-27 2000-12-27 The Trustees Of Dartmouth College Detection of gene sequences in biological fluids
JPH06167492A (ja) * 1992-11-30 1994-06-14 Otsuka Pharmaceut Co Ltd 変異癌遺伝子の検出測定方法
DE19512369A1 (de) * 1995-04-01 1996-10-02 Boehringer Mannheim Gmbh Vorrichtung zur Isolierung von Nukleinsäuren

Also Published As

Publication number Publication date
NO324963B1 (no) 2008-01-14
NO982246D0 (no) 1998-05-15
ATE318934T1 (de) 2006-03-15
EP0868529A1 (en) 1998-10-07
NO982246L (no) 1998-07-07
DE69635848D1 (de) 2006-04-27
ES2208766T3 (es) 2004-06-16
EP1394272B1 (en) 2006-03-01
NO954667D0 (no) 1995-11-17
AU7656996A (en) 1997-06-11
DE69635848T2 (de) 2006-11-30
ES2262930T3 (es) 2006-12-01
JP2000500346A (ja) 2000-01-18
DE69630234D1 (de) 2003-11-06
EP1394272A1 (en) 2004-03-03
ATE251222T1 (de) 2003-10-15
WO1997019191A1 (en) 1997-05-29
EP0868529B1 (en) 2003-10-01
DK0868529T3 (da) 2004-02-02
AU723980C (en) 2002-10-24
PT1394272E (pt) 2006-07-31
AU723980B2 (en) 2000-09-07
DE69630234T2 (de) 2004-08-19
US6440661B1 (en) 2002-08-27
NZ322619A (en) 1999-04-29
PT868529E (pt) 2004-02-27

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