DK1367063T3 - Fremgangsmåde til syntese af perindopril og farmaceutisk acceptable salte heraf - Google Patents
Fremgangsmåde til syntese af perindopril og farmaceutisk acceptable salte herafInfo
- Publication number
- DK1367063T3 DK1367063T3 DK03291931T DK03291931T DK1367063T3 DK 1367063 T3 DK1367063 T3 DK 1367063T3 DK 03291931 T DK03291931 T DK 03291931T DK 03291931 T DK03291931 T DK 03291931T DK 1367063 T3 DK1367063 T3 DK 1367063T3
- Authority
- DK
- Denmark
- Prior art keywords
- perindopril
- synthesis
- pharmaceutically acceptable
- acceptable salts
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03291931A EP1367063B1 (fr) | 2003-07-31 | 2003-07-31 | Nouveau procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1367063T3 true DK1367063T3 (da) | 2006-12-27 |
Family
ID=29414890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03291931T DK1367063T3 (da) | 2003-07-31 | 2003-07-31 | Fremgangsmåde til syntese af perindopril og farmaceutisk acceptable salte heraf |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7358372B2 (ru) |
| EP (1) | EP1367063B1 (ru) |
| JP (1) | JP4263743B2 (ru) |
| KR (1) | KR100798560B1 (ru) |
| CN (1) | CN100404548C (ru) |
| AR (1) | AR045151A1 (ru) |
| AT (1) | ATE337332T1 (ru) |
| AU (1) | AU2004261439B2 (ru) |
| BR (1) | BRPI0413169A (ru) |
| CA (1) | CA2533005C (ru) |
| CY (1) | CY1105791T1 (ru) |
| DE (1) | DE60307721T2 (ru) |
| DK (1) | DK1367063T3 (ru) |
| EA (1) | EA008685B1 (ru) |
| ES (1) | ES2271498T3 (ru) |
| GE (1) | GEP20094740B (ru) |
| HK (1) | HK1096406A1 (ru) |
| MA (1) | MA27911A1 (ru) |
| MX (1) | MXPA06001243A (ru) |
| MY (1) | MY139443A (ru) |
| NO (1) | NO333957B1 (ru) |
| NZ (1) | NZ544879A (ru) |
| PL (1) | PL211892B1 (ru) |
| PT (1) | PT1367063E (ru) |
| SI (1) | SI1367063T1 (ru) |
| UA (1) | UA80905C2 (ru) |
| WO (1) | WO2005012333A2 (ru) |
| ZA (1) | ZA200600479B (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
| WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
| FR3050380B1 (fr) | 2016-04-20 | 2020-07-10 | Les Laboratoires Servier | Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8604144A1 (es) * | 1984-11-21 | 1986-01-16 | Farmhispania | Procedimiento para la obtencion del acido (2s, 3as, 7as)-1-((s)-1-etoxicarbonil-3-fenilpropil) alanil) exahidro-2-indolincarboxilico |
| FR2807431B1 (fr) * | 2000-04-06 | 2002-07-19 | Adir | Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables |
| FR2827860B1 (fr) * | 2001-07-24 | 2004-12-10 | Servier Lab | Nouveau procede de synthese de derives de l'acide (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxyline et application a la synthese du perindopril |
-
2003
- 2003-07-31 SI SI200330430T patent/SI1367063T1/sl unknown
- 2003-07-31 PT PT03291931T patent/PT1367063E/pt unknown
- 2003-07-31 ES ES03291931T patent/ES2271498T3/es not_active Expired - Lifetime
- 2003-07-31 AT AT03291931T patent/ATE337332T1/de active
- 2003-07-31 EP EP03291931A patent/EP1367063B1/fr not_active Expired - Lifetime
- 2003-07-31 DK DK03291931T patent/DK1367063T3/da active
- 2003-07-31 DE DE60307721T patent/DE60307721T2/de not_active Expired - Lifetime
-
2004
- 2004-07-29 WO PCT/FR2004/002035 patent/WO2005012333A2/fr active Application Filing
- 2004-07-29 MX MXPA06001243A patent/MXPA06001243A/es active IP Right Grant
- 2004-07-29 CA CA2533005A patent/CA2533005C/fr not_active Expired - Fee Related
- 2004-07-29 BR BRPI0413169-0A patent/BRPI0413169A/pt active Search and Examination
- 2004-07-29 ZA ZA200600479A patent/ZA200600479B/en unknown
- 2004-07-29 UA UAA200602130A patent/UA80905C2/xx unknown
- 2004-07-29 US US10/566,562 patent/US7358372B2/en not_active Expired - Fee Related
- 2004-07-29 JP JP2006521621A patent/JP4263743B2/ja not_active Expired - Fee Related
- 2004-07-29 MY MYPI20043053A patent/MY139443A/en unknown
- 2004-07-29 EA EA200600250A patent/EA008685B1/ru not_active IP Right Cessation
- 2004-07-29 AU AU2004261439A patent/AU2004261439B2/en not_active Ceased
- 2004-07-29 KR KR1020067001920A patent/KR100798560B1/ko not_active IP Right Cessation
- 2004-07-29 PL PL379631A patent/PL211892B1/pl unknown
- 2004-07-29 AR ARP040102693A patent/AR045151A1/es not_active Application Discontinuation
- 2004-07-29 GE GEAP20049261A patent/GEP20094740B/en unknown
- 2004-07-29 CN CNB2004800212090A patent/CN100404548C/zh not_active Expired - Fee Related
- 2004-07-29 NZ NZ544879A patent/NZ544879A/en not_active IP Right Cessation
-
2006
- 2006-01-17 MA MA28731A patent/MA27911A1/fr unknown
- 2006-02-24 NO NO20060922A patent/NO333957B1/no not_active IP Right Cessation
- 2006-11-16 CY CY20061101673T patent/CY1105791T1/el unknown
-
2007
- 2007-02-01 HK HK07101182A patent/HK1096406A1/xx not_active IP Right Cessation
Also Published As
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