DK1362039T3 - Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin D3-receptorligander - Google Patents

Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin D3-receptorligander

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Publication number
DK1362039T3
DK1362039T3 DK02718999T DK02718999T DK1362039T3 DK 1362039 T3 DK1362039 T3 DK 1362039T3 DK 02718999 T DK02718999 T DK 02718999T DK 02718999 T DK02718999 T DK 02718999T DK 1362039 T3 DK1362039 T3 DK 1362039T3
Authority
DK
Denmark
Prior art keywords
disorders
dopamine
compounds
substituted carbonyl
heterocyclic substituted
Prior art date
Application number
DK02718999T
Other languages
Danish (da)
English (en)
Inventor
James P Carey
George E Lee
James A Hendrix
Paul Angell
Nicola Collar
Horst Hemmerle
Kenneth J Bordeau
Matthias Urmann
Gregory Shutske
Joseph T Strupczewski
John G Jurcak
Thaddeus Nieduzak
Sharon Anne Jackson
David M Fink
Jean-Francois Sabuco
Yulin Chiang
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0117577.7A external-priority patent/GB0117577D0/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK1362039T3 publication Critical patent/DK1362039T3/da

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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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DK02718999T 2001-02-16 2002-02-15 Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin D3-receptorligander DK1362039T3 (da)

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WO2002066446A1 (en) 2002-08-29
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AU2002250107B2 (en) 2008-05-29
EP1632483A1 (en) 2006-03-08
ATE455108T1 (de) 2010-01-15
ATE313534T1 (de) 2006-01-15
DE60208157T2 (de) 2006-08-10
MXPA03006943A (es) 2005-04-29
DE60208157D1 (de) 2006-01-26
EP1362039B1 (en) 2005-12-21
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JP2009185055A (ja) 2009-08-20
ATE412638T1 (de) 2008-11-15
EP1935887A1 (en) 2008-06-25
AU2002250107B8 (en) 2008-06-12
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