DK1632483T3 - Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin-D3-receptorligander - Google Patents

Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin-D3-receptorligander

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Publication number
DK1632483T3
DK1632483T3 DK05018120T DK05018120T DK1632483T3 DK 1632483 T3 DK1632483 T3 DK 1632483T3 DK 05018120 T DK05018120 T DK 05018120T DK 05018120 T DK05018120 T DK 05018120T DK 1632483 T3 DK1632483 T3 DK 1632483T3
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DK
Denmark
Prior art keywords
disorders
dopamine
compounds
substituted carbonyl
heterocyclic substituted
Prior art date
Application number
DK05018120T
Other languages
English (en)
Inventor
James A Hendrix
Horst Hemmerle
Matthias Urmann
Gregory M Shutske
Joseph T Strupczewski
Kenneth J Bordeau
John G Jurcak
Thaddeus Nieduzak
Sharon Anne Jackson
Paul Angell
James P Carey
George E Lee
David M Fink
Jean-Francois Sabuco
Yulin Chiang
Nicola Collar
Original Assignee
Aventis Pharma Inc
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Filing date
Publication date
Priority claimed from GBGB0117577.7A external-priority patent/GB0117577D0/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK1632483T3 publication Critical patent/DK1632483T3/da

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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DK05018120T 2001-02-16 2002-02-15 Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin-D3-receptorligander DK1632483T3 (da)

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US26967201P 2001-02-16 2001-02-16
GBGB0117577.7A GB0117577D0 (en) 2001-02-16 2001-07-19 Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
PCT/US2002/004713 WO2002066446A1 (en) 2001-02-16 2002-02-15 Heterocyclic substituted carbonyl derivatives and their use as dopamine d3 receptor ligands

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DK1362039T3 (da) 2006-05-08
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EP1935887A1 (en) 2008-06-25
DE60208157D1 (de) 2006-01-26
EP1632483B1 (en) 2008-10-29
ATE412638T1 (de) 2008-11-15
JP2009185054A (ja) 2009-08-20
AU2002250107B8 (en) 2008-06-12
PT1632483E (pt) 2009-01-12
ATE313534T1 (de) 2006-01-15
ES2317116T3 (es) 2009-04-16
AU2002250107B2 (en) 2008-05-29
EP1632483A1 (en) 2006-03-08
EP1362039A1 (en) 2003-11-19
IL157413A0 (en) 2004-03-28
CA2438264A1 (en) 2002-08-29
EP1935887B1 (en) 2010-01-13
WO2002066446A1 (en) 2002-08-29
JP2009185055A (ja) 2009-08-20
DE60208157T2 (de) 2006-08-10
ES2253526T3 (es) 2006-06-01
ATE455108T1 (de) 2010-01-15
MXPA03006943A (es) 2005-04-29

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