DK1307237T3 - Perfluoralkylholdige komplekser med polære grupper, fremgangsmåde til fremstilling og anvendelse heraf - Google Patents
Perfluoralkylholdige komplekser med polære grupper, fremgangsmåde til fremstilling og anvendelse herafInfo
- Publication number
- DK1307237T3 DK1307237T3 DK01958005T DK01958005T DK1307237T3 DK 1307237 T3 DK1307237 T3 DK 1307237T3 DK 01958005 T DK01958005 T DK 01958005T DK 01958005 T DK01958005 T DK 01958005T DK 1307237 T3 DK1307237 T3 DK 1307237T3
- Authority
- DK
- Denmark
- Prior art keywords
- perfluoroalkyl
- preparation
- polar groups
- containing complexes
- complexes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10040858A DE10040858C2 (de) | 2000-08-11 | 2000-08-11 | Perfluoralkylhaltige Komplexe mit polaren Resten, Verfahren zu deren Herstellung und ihre Verwendung |
| PCT/EP2001/008500 WO2002013875A2 (de) | 2000-08-11 | 2001-07-23 | Perfluoralkylhaltige komplexe mit polaren resten, verfahren zu deren herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1307237T3 true DK1307237T3 (da) | 2007-07-02 |
Family
ID=7653176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01958005T DK1307237T3 (da) | 2000-08-11 | 2001-07-23 | Perfluoralkylholdige komplekser med polære grupper, fremgangsmåde til fremstilling og anvendelse heraf |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1307237B9 (ru) |
| JP (1) | JP2004506026A (ru) |
| KR (2) | KR20030022381A (ru) |
| CN (1) | CN1468113A (ru) |
| AR (1) | AR035342A1 (ru) |
| AT (1) | ATE359093T1 (ru) |
| AU (2) | AU2001279777B2 (ru) |
| BG (1) | BG107541A (ru) |
| BR (1) | BR0113187A (ru) |
| CA (1) | CA2419259A1 (ru) |
| CZ (1) | CZ2003341A3 (ru) |
| DE (2) | DE10040858C2 (ru) |
| DK (1) | DK1307237T3 (ru) |
| EE (1) | EE200300060A (ru) |
| ES (1) | ES2284671T3 (ru) |
| HR (1) | HRP20030171A2 (ru) |
| HU (1) | HUP0300769A3 (ru) |
| IL (1) | IL154329A0 (ru) |
| MX (1) | MXPA03001286A (ru) |
| NO (1) | NO20030649L (ru) |
| NZ (1) | NZ524080A (ru) |
| PL (1) | PL365367A1 (ru) |
| PT (1) | PT1307237E (ru) |
| RU (1) | RU2289579C2 (ru) |
| SK (1) | SK286239B6 (ru) |
| UA (1) | UA74004C2 (ru) |
| UY (1) | UY26873A1 (ru) |
| WO (1) | WO2002013875A2 (ru) |
| YU (1) | YU10503A (ru) |
| ZA (1) | ZA200301947B (ru) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344704B2 (en) | 2002-07-10 | 2008-03-18 | Schering Ag | Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi |
| DE10231799B4 (de) * | 2002-07-10 | 2006-10-05 | Schering Ag | Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben |
| JP2009509915A (ja) * | 2005-07-15 | 2009-03-12 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | ペルフルオロアルキル含有錯体、ならびにｎｍｒ、ｘ線および放射線診断、さらに放射線治療のための造影剤としてのその使用法 |
| DE102005033902B3 (de) * | 2005-07-15 | 2007-04-05 | Schering Ag | Perfluoralkylhaltige Komplexe, Verfahren zu deren Herstellung, sowie deren Verwendung und diese enthaltende pharmazeutische Mittel |
| DE102005033903B4 (de) * | 2005-07-15 | 2007-08-09 | Bayer Schering Pharma Ag | Perfluoralkylhaltige Komplexe, Verfahren zu deren Herstellung, sowie deren Verwendung und diese enthaltende pharmazeutische Mittel |
| DE102006049821A1 (de) * | 2006-10-18 | 2008-04-24 | Bayer Schering Pharma Aktiengesellschaft | Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung |
| DE102007015598A1 (de) * | 2007-03-29 | 2008-10-02 | Heinrich-Heine-Universität Düsseldorf | Verwendung von fluorhaltigen Verbindungen zu Diagnosezwecken mit Hilfe bildgebender Verfahren |
| EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
| WO2018096082A1 (en) | 2016-11-28 | 2018-05-31 | Bayer Pharma Aktiengesellschaft | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging |
| RU2681319C1 (ru) * | 2017-10-27 | 2019-03-06 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский экономический университет имени Г.В. Плеханова" (ФГБОУ ВО "РЭУ им. Г.В. Плеханова") | Ультраволокнистый биополимерный материал с бактерицидным эффектом |
| CA3120665A1 (en) | 2018-11-23 | 2020-05-28 | Bayer Aktiengesellschaft | Formulation of contrast media and process of preparation thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317588C2 (de) * | 1993-05-24 | 1998-04-16 | Schering Ag | Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung |
| DE19603033A1 (de) * | 1996-01-19 | 1997-07-24 | Schering Ag | Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
| DE19608278A1 (de) * | 1996-02-23 | 1997-08-28 | Schering Ag | Pharmazeutische Mittel enthaltend perfluoralkylhaltige Metallkomplexe, und ihre Verwendung in der Tumortherapie und interventioniellen Radiologie |
| DE19729013A1 (de) * | 1997-07-03 | 1999-02-04 | Schering Ag | Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
| DE19744004C1 (de) * | 1997-09-26 | 1999-07-22 | Schering Ag | Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging |
-
2000
- 2000-08-11 DE DE10040858A patent/DE10040858C2/de not_active Expired - Fee Related
-
2001
- 2001-07-23 YU YU10503A patent/YU10503A/sh unknown
- 2001-07-23 BR BR0113187-7A patent/BR0113187A/pt not_active IP Right Cessation
- 2001-07-23 RU RU2003105813/04A patent/RU2289579C2/ru not_active IP Right Cessation
- 2001-07-23 PL PL01365367A patent/PL365367A1/xx unknown
- 2001-07-23 WO PCT/EP2001/008500 patent/WO2002013875A2/de active IP Right Grant
- 2001-07-23 AT AT01958005T patent/ATE359093T1/de not_active IP Right Cessation
- 2001-07-23 DE DE50112336T patent/DE50112336D1/de not_active Expired - Fee Related
- 2001-07-23 JP JP2002519013A patent/JP2004506026A/ja not_active Withdrawn
- 2001-07-23 HU HU0300769A patent/HUP0300769A3/hu unknown
- 2001-07-23 PT PT01958005T patent/PT1307237E/pt unknown
- 2001-07-23 AU AU2001279777A patent/AU2001279777B2/en not_active Ceased
- 2001-07-23 CA CA002419259A patent/CA2419259A1/en not_active Abandoned
- 2001-07-23 ES ES01958005T patent/ES2284671T3/es not_active Expired - Lifetime
- 2001-07-23 IL IL15432901A patent/IL154329A0/xx not_active IP Right Cessation
- 2001-07-23 KR KR10-2003-7001937A patent/KR20030022381A/ko not_active Application Discontinuation
- 2001-07-23 KR KR1020087003857A patent/KR20080027397A/ko not_active Application Discontinuation
- 2001-07-23 AU AU7977701A patent/AU7977701A/xx active Pending
- 2001-07-23 NZ NZ524080A patent/NZ524080A/en unknown
- 2001-07-23 DK DK01958005T patent/DK1307237T3/da active
- 2001-07-23 UA UA2003032068A patent/UA74004C2/uk unknown
- 2001-07-23 MX MXPA03001286A patent/MXPA03001286A/es not_active Application Discontinuation
- 2001-07-23 EE EEP200300060A patent/EE200300060A/xx unknown
- 2001-07-23 CZ CZ2003341A patent/CZ2003341A3/cs unknown
- 2001-07-23 EP EP01958005A patent/EP1307237B9/de not_active Expired - Lifetime
- 2001-07-23 CN CNA018170765A patent/CN1468113A/zh active Pending
- 2001-07-23 SK SK155-2003A patent/SK286239B6/sk unknown
- 2001-08-07 UY UY26873A patent/UY26873A1/es not_active Application Discontinuation
- 2001-08-10 AR ARP010103832A patent/AR035342A1/es unknown
-
2003
- 2003-02-07 BG BG107541A patent/BG107541A/bg unknown
- 2003-02-10 NO NO20030649A patent/NO20030649L/no not_active Application Discontinuation
- 2003-03-10 HR HR20030171A patent/HRP20030171A2/hr not_active Application Discontinuation
- 2003-03-10 ZA ZA200301947A patent/ZA200301947B/en unknown
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