AU7977701A - Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof - Google Patents

Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof

Info

Publication number
AU7977701A
AU7977701A AU7977701A AU7977701A AU7977701A AU 7977701 A AU7977701 A AU 7977701A AU 7977701 A AU7977701 A AU 7977701A AU 7977701 A AU7977701 A AU 7977701A AU 7977701 A AU7977701 A AU 7977701A
Authority
AU
Australia
Prior art keywords
production
complexes containing
containing perfluoroalkyl
polar radicals
radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU7977701A
Inventor
Johannes Dr Platzek
Peter Mareski
Ulrich Niedballa
Bernd Dr Raduchel
Hanns-Joachim Weinmann
Bernd Misselwitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU7977701A publication Critical patent/AU7977701A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU7977701A 2000-08-11 2001-07-23 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof Pending AU7977701A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10040858A DE10040858C2 (en) 2000-08-11 2000-08-11 Perfluoroalkyl-containing complexes with polar residues, process for their preparation and their use
PCT/EP2001/008500 WO2002013875A2 (en) 2000-08-11 2001-07-23 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof

Publications (1)

Publication Number Publication Date
AU7977701A true AU7977701A (en) 2002-02-25

Family

ID=7653176

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001279777A Ceased AU2001279777B2 (en) 2000-08-11 2001-07-23 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof
AU7977701A Pending AU7977701A (en) 2000-08-11 2001-07-23 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU2001279777A Ceased AU2001279777B2 (en) 2000-08-11 2001-07-23 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof

Country Status (30)

Country Link
EP (1) EP1307237B9 (en)
JP (1) JP2004506026A (en)
KR (2) KR20030022381A (en)
CN (1) CN1468113A (en)
AR (1) AR035342A1 (en)
AT (1) ATE359093T1 (en)
AU (2) AU2001279777B2 (en)
BG (1) BG107541A (en)
BR (1) BR0113187A (en)
CA (1) CA2419259A1 (en)
CZ (1) CZ2003341A3 (en)
DE (2) DE10040858C2 (en)
DK (1) DK1307237T3 (en)
EE (1) EE200300060A (en)
ES (1) ES2284671T3 (en)
HR (1) HRP20030171A2 (en)
HU (1) HUP0300769A3 (en)
IL (1) IL154329A0 (en)
MX (1) MXPA03001286A (en)
NO (1) NO20030649L (en)
NZ (1) NZ524080A (en)
PL (1) PL365367A1 (en)
PT (1) PT1307237E (en)
RU (1) RU2289579C2 (en)
SK (1) SK286239B6 (en)
UA (1) UA74004C2 (en)
UY (1) UY26873A1 (en)
WO (1) WO2002013875A2 (en)
YU (1) YU10503A (en)
ZA (1) ZA200301947B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344704B2 (en) 2002-07-10 2008-03-18 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
DE10231799B4 (en) * 2002-07-10 2006-10-05 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast agents in MR imaging for the presentation of intravascular thrombi
DE102005033903B4 (en) * 2005-07-15 2007-08-09 Bayer Schering Pharma Ag Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them
EP1904462A2 (en) * 2005-07-15 2008-04-02 Bayer Schering Pharma Aktiengesellschaft Complexes containing perfluoroalkyl, method for the production and use thereof
DE102005033902B3 (en) * 2005-07-15 2007-04-05 Schering Ag Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them
DE102006049821A1 (en) 2006-10-18 2008-04-24 Bayer Schering Pharma Aktiengesellschaft New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues
DE102007015598A1 (en) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Use of fluorochemical compounds for diagnostic purposes using imaging techniques
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
CN110035996B (en) 2016-11-28 2022-08-09 拜耳医药股份公司 Novel highly relaxant gadolinium chelates for magnetic resonance imaging
RU2681319C1 (en) * 2017-10-27 2019-03-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский экономический университет имени Г.В. Плеханова" (ФГБОУ ВО "РЭУ им. Г.В. Плеханова") Ultra-fibrous biopolymer material with bactericidal effect
KR20210095168A (en) 2018-11-23 2021-07-30 바이엘 악티엔게젤샤프트 Formulation of Contrast Media and Method for Preparing Same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317588C2 (en) * 1993-05-24 1998-04-16 Schering Ag Macrocyclic metal complexes containing fluorine, process for their preparation and their use
DE19603033A1 (en) * 1996-01-19 1997-07-24 Schering Ag Perfluoroalkyl-containing metal complexes, processes for their preparation and their use in NMR diagnostics
DE19608278A1 (en) * 1996-02-23 1997-08-28 Schering Ag Pharmaceutical compositions containing perfluoroalkyl-containing metal complexes, and their use in tumor therapy and interventional radiology
DE19729013A1 (en) * 1997-07-03 1999-02-04 Schering Ag Oligomeric, perfluoroalkyl-containing compounds, processes for their preparation and their use in NMR diagnostics
DE19744004C1 (en) * 1997-09-26 1999-07-22 Schering Ag Lipophilic metal complexes for necrosis and infarct imaging

Also Published As

Publication number Publication date
CA2419259A1 (en) 2002-02-21
AU2001279777B2 (en) 2006-08-31
CN1468113A (en) 2004-01-14
HUP0300769A2 (en) 2003-09-29
SK1552003A3 (en) 2003-09-11
HRP20030171A2 (en) 2004-06-30
NO20030649L (en) 2003-04-11
PL365367A1 (en) 2004-12-27
KR20080027397A (en) 2008-03-26
EP1307237A2 (en) 2003-05-07
DE10040858C2 (en) 2003-12-18
YU10503A (en) 2006-08-17
DE10040858A1 (en) 2002-03-28
RU2289579C2 (en) 2006-12-20
CZ2003341A3 (en) 2003-05-14
BR0113187A (en) 2003-07-01
AR035342A1 (en) 2004-05-12
ATE359093T1 (en) 2007-05-15
KR20030022381A (en) 2003-03-15
DE50112336D1 (en) 2007-05-24
ES2284671T3 (en) 2007-11-16
UY26873A1 (en) 2002-03-22
UA74004C2 (en) 2005-10-17
JP2004506026A (en) 2004-02-26
EP1307237B9 (en) 2008-01-09
SK286239B6 (en) 2008-06-06
NO20030649D0 (en) 2003-02-10
IL154329A0 (en) 2003-09-17
WO2002013875A3 (en) 2002-08-22
ZA200301947B (en) 2004-06-25
HUP0300769A3 (en) 2009-03-02
EP1307237B1 (en) 2007-04-11
BG107541A (en) 2004-01-30
EE200300060A (en) 2004-12-15
NZ524080A (en) 2005-10-28
PT1307237E (en) 2007-07-02
WO2002013875A2 (en) 2002-02-21
MXPA03001286A (en) 2004-04-20
DK1307237T3 (en) 2007-07-02

Similar Documents

Publication Publication Date Title
TWI315741B (en) A-isomaltosyltransferase, process for producing the same and use thereof
AU2002310741A1 (en) Superabsorber, method for the production and use thereof
HK1094433A1 (en) Flocculating agent, method for the production and use thereof
HUP0401293A3 (en) Novel dihydropteridinones, method for producing the same and the use thereof as medicaments
HK1068379A1 (en) Polytetrafluoroethylene fiber and method for manufacturing the same
AU2001276295A1 (en) Electric component, method for the production thereof, and its use
IL161893A0 (en) 5-Phenylpyrimidines, agents comprising the same, method for production and use thereof
IL162316A0 (en) Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use thereof as medicaments, in addition t
EG23201A (en) Water filters and processes for using the same.
HUP0300769A3 (en) Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof
AU2001279777A1 (en) Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof
PL366168A1 (en) Impregnate, method for the production and use thereof
IL174975A0 (en) 2-phenyl-benzofuran derivatives, method for the production thereof and their use
GB2370808B (en) Laminates and methods for manufacturing the same
PL371193A1 (en) Multilayered films, method for the production and use thereof
AU2796602A (en) Coniosetin and derivatives thereof, method for producing the same and use thereof
HUP0300306A3 (en) Cyclipostins, a method for their production and the use of the same
EP1273657A4 (en) Novel protein, process for producing the same and use thereof
AU2002348998A1 (en) N-methyl-homocystines, use thereof and method for the production thereof
EP1489087A4 (en) Bisphosphine, process for producing the same, and use thereof
HK1061655A1 (en) Caloporoside derivatives, methods for the production thereof and their use
MXPA03004632A (en) Klainetin and derivatives thereof, method for their production and the use of the same.
AU2002256705A1 (en) Corrosion-stable laminate, method for the production thereof, and its use
AU6730001A (en) Component, method for production and use thereof
EP1295940A4 (en) Polypeptides, use thereof and process for producing the same