DK1261694T3 - Pluripotente stamceller som er genereret ud fra stromaceller der er afledt af adipöst væv samt anvendelser deraf - Google Patents

Pluripotente stamceller som er genereret ud fra stromaceller der er afledt af adipöst væv samt anvendelser deraf

Info

Publication number
DK1261694T3
DK1261694T3 DK01911175T DK01911175T DK1261694T3 DK 1261694 T3 DK1261694 T3 DK 1261694T3 DK 01911175 T DK01911175 T DK 01911175T DK 01911175 T DK01911175 T DK 01911175T DK 1261694 T3 DK1261694 T3 DK 1261694T3
Authority
DK
Denmark
Prior art keywords
adipose tissue
applications
well
pluripotent stem
stem cells
Prior art date
Application number
DK01911175T
Other languages
Danish (da)
English (en)
Inventor
William O Wilkison
Jeffrey Gimble
Original Assignee
Artecel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Artecel Inc filed Critical Artecel Inc
Application granted granted Critical
Publication of DK1261694T3 publication Critical patent/DK1261694T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/44—Thiols, e.g. mercaptoethanol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK01911175T 2000-02-26 2001-02-26 Pluripotente stamceller som er genereret ud fra stromaceller der er afledt af adipöst væv samt anvendelser deraf DK1261694T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18533800P 2000-02-26 2000-02-26
PCT/US2001/006106 WO2001062901A2 (fr) 2000-02-26 2001-02-26 Cellules souches multipotentes, produites a partir de cellules de stroma derivees de tissus adipeux, et utilisations associees

Publications (1)

Publication Number Publication Date
DK1261694T3 true DK1261694T3 (da) 2008-05-26

Family

ID=22680577

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01911175T DK1261694T3 (da) 2000-02-26 2001-02-26 Pluripotente stamceller som er genereret ud fra stromaceller der er afledt af adipöst væv samt anvendelser deraf

Country Status (13)

Country Link
US (2) US7078230B2 (fr)
EP (1) EP1261694B1 (fr)
JP (1) JP2003523767A (fr)
AT (1) ATE384124T1 (fr)
AU (2) AU2001238695B2 (fr)
CA (1) CA2400485C (fr)
DE (1) DE60132429T2 (fr)
DK (1) DK1261694T3 (fr)
ES (1) ES2300320T3 (fr)
IL (1) IL151228A (fr)
PT (1) PT1261694E (fr)
SG (1) SG134168A1 (fr)
WO (1) WO2001062901A2 (fr)

Families Citing this family (152)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69841850D1 (de) 1997-12-02 2010-09-30 Artecel Sciences Inc Differenzierung in osteoblasten der fettgewebe-stromalen zellen und ihre verwendungen
US20050153442A1 (en) * 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
KR100979664B1 (ko) * 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
US20030082152A1 (en) * 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
US20050076396A1 (en) * 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
DK1226233T3 (da) * 1999-08-05 2011-10-03 Abt Holding Co Multipotente voksne stamceller og fremgangsmåder til isolering heraf
US8609412B2 (en) * 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
US8075881B2 (en) 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
ATE384124T1 (de) * 2000-02-26 2008-02-15 Artecel Inc Pluripotente stammzellen erzeugt aus stromalzellen aus dem fettgewebe und deren verwendungen
US7582292B2 (en) * 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
US6673606B1 (en) * 2000-04-12 2004-01-06 The Children's Hospital Of Philadelphia Therapeutic uses for mesenchymal stromal cells
US7473555B2 (en) 2000-04-27 2009-01-06 Geron Corporation Protocols for making hepatocytes from embryonic stem cells
US7282366B2 (en) 2000-04-27 2007-10-16 Geron Corporation Hepatocytes for therapy and drug screening made from embryonic stem cells
US7256042B2 (en) 2000-04-27 2007-08-14 Geron Corporation Process for making hepatocytes from pluripotent stem cells
US6458589B1 (en) * 2000-04-27 2002-10-01 Geron Corporation Hepatocyte lineage cells derived from pluripotent stem cells
FR2819265B1 (fr) * 2001-01-10 2004-01-02 Centre Nat Rech Scient Cellules du tissu adipeux extramedullaire et leurs applications dans la reconstitution des lignees hematopoietiques
JP2004529621A (ja) 2001-02-14 2004-09-30 ティー ファークト，レオ 多能性成体幹細胞、その起源、それを得る方法および維持する方法、それを分化させる方法、その使用法、ならびにそれ由来の細胞
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
CA2465950A1 (fr) * 2001-11-09 2003-05-15 Artecel Sciences, Inc. Differenciation pancreatique endocrine de cellules stromales derivees du tissu adipeux et utilisation desdites cellules
CN1596303A (zh) * 2001-11-09 2005-03-16 阿特塞尔科学公司 利用基质细胞支持胚胎干细胞和成体干细胞的方法和组合物
CN100516200C (zh) * 2001-11-09 2009-07-22 阿特塞尔科学公司 用于角膜和眶内缺损修复的脂肪组织来源的基质细胞及其应用
US8404229B2 (en) * 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
US20050095228A1 (en) * 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
AU2002357135C1 (en) 2001-12-07 2009-01-22 Macropore Biosurgery, Inc. Systems and methods for treating patients with processed lipoaspirate cells
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US7595043B2 (en) * 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
AU2003220424A1 (en) * 2002-03-19 2003-10-08 Advanced Research And Technology Transfer Adipose stromal stem cells for tissue and vascular modification
AU2003230792A1 (en) * 2002-04-03 2003-10-20 Artecel Sciences, Inc. Improvements of adipocytic differentiated adipose derived adult stem cells and uses thereof
US20060084170A1 (en) * 2002-05-24 2006-04-20 Pykett Mark J Cytokine-free growth and maintenance of progenitor cells
WO2004050859A2 (fr) 2002-11-27 2004-06-17 Regents Of The University Of Minnesota Recombinaison homologue dans des cellules souches adultes multipotentes
FR2850009B1 (fr) * 2003-01-20 2005-12-23 Spine Next Sa Ensemble de traitement de la degenerescence d'un disque intervertebral
US20040193274A1 (en) * 2003-03-28 2004-09-30 Trieu Hai H. Materials and methods for augmenting and/or repairing intervertebral discs
WO2005035738A1 (fr) 2003-10-07 2005-04-21 Biomaster Inc. Differentiation cellulaire de cellules precurseurs issus des tissus adipeux
NZ597965A (en) 2003-10-08 2013-09-27 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
WO2005042048A2 (fr) * 2003-10-22 2005-05-12 Encelle, Inc. Methodes et compositions destinees a regenerer le tissu conjonctif
CN1871343B (zh) * 2003-11-04 2013-06-26 株式会社宝玛斯特 从脂肪组织制备干细胞的方法和系统
EP2824174B1 (fr) 2004-03-22 2018-11-28 Mesoblast International Sàrl Cellules souches mésenchymateuses et utilisations associées
WO2005093083A1 (fr) * 2004-03-29 2005-10-06 Kazuhisa Maeda Procédé pour la prédiction de maladies et procédé utilisant celui-ci
JP2007252393A (ja) * 2004-04-28 2007-10-04 Nippon Medical School 脂肪組織由来幹細胞から骨髄を形成するための組成物およびその方法
WO2006014156A1 (fr) * 2004-07-02 2006-02-09 Macropore Biosurgery, Inc. Systemes et procedes pour isoler et utiliser des cellules regeneratives cliniquement sures derivees de tissus adipeux
ES2313805B1 (es) * 2004-10-04 2009-12-23 Cellerix, S.L. Identificacion y aislamiento de celulas multipotentes de tejido mesenquimal no osteocondral.
US20060051865A1 (en) * 2004-08-31 2006-03-09 Higgins Joel C Systems and methods for isolating stromal cells from adipose tissue and uses thereof
WO2006046583A1 (fr) * 2004-10-26 2006-05-04 Santen Pharmaceutical Co., Ltd. Matériau pour régénérer les cellules visuelles ou rétablir les fonctions de celles-ci
EP1844434A4 (fr) * 2005-01-10 2013-11-13 Cytori Therapeutics Inc Appareil et procede de suivi, gestion et entretien de dispositifs medicaux
KR20070100908A (ko) * 2005-01-31 2007-10-12 코그네이트 세러퓨틱 인크. 내피 세포의 특성을 나타내는 지방 유래 성인 스트로마세포
WO2006086639A1 (fr) * 2005-02-10 2006-08-17 Regents Of The University Of Minnesota Cellules endotheliales vasculaires/lymphatiques
AU2005331534B2 (en) * 2005-05-05 2011-12-08 Regents Of The University Of Minnesota Use of MAPC or progeny therefrom to populate lymphohematopoietic tissues
WO2006128029A2 (fr) * 2005-05-25 2006-11-30 University Of Virginia Patent Foundation Production d'osteoclastes a partir de tissus adipeux
WO2007117262A2 (fr) * 2005-07-29 2007-10-18 Athersys, Inc. Culture de cellules non embryonnaires à haute densité cellulaire
US7531355B2 (en) * 2005-07-29 2009-05-12 The Regents Of The University Of California Methods and compositions for smooth muscle reconstruction
WO2007030469A2 (fr) * 2005-09-06 2007-03-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Niche de croissance cellulaire transplantable, compositions et methodes associees
WO2007047509A2 (fr) 2005-10-14 2007-04-26 Regents Of The University Of Minnesota Differenciation de cellules souches non-embryonnaires avec des cellules possedant un phenotype pancreatique
WO2007055882A2 (fr) * 2005-11-07 2007-05-18 Hosheng Tu Systeme d’augmentation mammaire et de reconstruction
US20070104693A1 (en) * 2005-11-07 2007-05-10 Quijano Rodolfo C Breast augmentation system
US20070104692A1 (en) * 2005-11-07 2007-05-10 Quijano Rodolfo C Breast tissue regeneration
KR100679642B1 (ko) * 2005-11-16 2007-02-06 주식회사 알앤엘바이오 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제
FR2896511B1 (fr) * 2006-01-26 2012-10-26 Centre Nat Rech Scient Procede de culture de cellules issues du tissu adipeux et leurs applications.
JP2009525044A (ja) * 2006-01-30 2009-07-09 ユニバーシティ オブ バージニア パテント ファウンデーション 間葉系幹細胞集合体を調製および特性評価する方法ならびにそれらの使用
WO2007091790A1 (fr) * 2006-02-07 2007-08-16 Korea Institute Of Radiological & Medical Sciences Composition destinée au traitement d'une lésion du système nerveux central ou périphérique
EP2366775B1 (fr) 2006-03-23 2015-04-22 Pluristem Ltd. Procédés de développement cellulaire et utilisations thérapeutiques des cellules et des milieux conditionnés produits de cette maniere
RU2008146395A (ru) 2006-04-25 2010-05-27 Борд Ов Супервайзорс Ов Луизиана Стейт Юниверсити Энд Агрикалчарал Энд Микэникал Колледж (Us) Стволовые клетки жировой ткани взрослого человека в регенерации печени
EP3001902A1 (fr) * 2006-05-17 2016-04-06 Cognate Therapeutics, Inc. Isolation et purification de cellules souches hématopoïétiques à partir d'aspirats de liposuccion
FR2901136B1 (fr) * 2006-05-18 2010-10-01 Centre Nat Rech Scient Utilisation de cellules derivees du tissu adipeux pour la preparation d'un medicament anti-tumoral
US20090304644A1 (en) * 2006-05-30 2009-12-10 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue
US8148151B2 (en) 2006-06-02 2012-04-03 Geron Corporation Differentiation of primate pluripotent cells to hepatocyte-lineage cells
FR2902011B1 (fr) * 2006-06-12 2008-12-26 Inst Radioprot Et De Surete Nu Utilisation de fractions cellulaires du tissu adipeux pour la regeneration tissulaire post irradiation
JP2009539546A (ja) * 2006-06-15 2009-11-19 アールエヌエル バイオ カンパニー，リミティッド ヒト脂肪組織由来成体幹細胞、繊維芽細胞、及び脂肪又は脂肪細胞を含有する皮膚美容又は形成用の組成物
WO2008013863A2 (fr) * 2006-07-26 2008-01-31 Cytori Therapeutics, Inc. Génération d'un tissu adipeux et d'adipocytes
JP2010505849A (ja) * 2006-10-06 2010-02-25 ユニバーシティ オブ バージニア パテント ファウンデーション 糖尿病性創傷治癒に有用な方法および組成物
WO2008060788A2 (fr) * 2006-10-11 2008-05-22 The General Hospital Corporation Compositions, procédés, et dispositifs destinés à traiter les maladies hépatiques
US9005964B2 (en) 2006-11-24 2015-04-14 Regents Of The University Of Minnesota Endodermal progenitor cells
WO2008103807A2 (fr) * 2007-02-21 2008-08-28 Cedars-Sinai Medical Center Méthodes de production de préadipocytes et d'augmentation de la prolifération de cellules souches/progénitrices adipeuses adultes
WO2008132722A1 (fr) 2007-04-26 2008-11-06 Ramot At Tel-Aviv University Ltd. Cellules souches autologues pluripotentes de muqueuse buccale et procédé d'utilisation
BRPI0815946B8 (pt) 2007-09-19 2021-05-25 Pluristem Ltd artigo de fabricação
US8273091B2 (en) * 2007-10-04 2012-09-25 Ebi, Llc Alignment device for locking nail
WO2009069991A2 (fr) * 2007-11-30 2009-06-04 Rnl Bio Co., Ltd. Agent thérapeutique cellulaire pour incontinence urinaire comprenant des cellules souches provenant de la caduque ou de l'adipose
AU2009205886B2 (en) 2008-01-18 2015-08-27 Katholieke Universiteit Leuven Stem cell aggregates and methods for making and using
US9422522B2 (en) 2008-02-05 2016-08-23 Regenertech Pty Limited Method of producing adipocytes from fibroblast cells
US9393273B2 (en) 2008-05-27 2016-07-19 Pluristem Ltd. Methods of treating inflammatory colon diseases
WO2010021993A1 (fr) * 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Procédés d'utilisation de cellules issues du tissu adipeux dans le traitement du système lymphatique et d'une maladie maligne
CN105708862B (zh) 2008-09-02 2020-11-06 普拉里斯坦有限公司 来自胎盘组织的粘附细胞及其在治疗中的用途
WO2010049752A1 (fr) 2008-10-31 2010-05-06 Katholieke Universiteit Leuven Procédés optimisés pour la différenciation de cellules en cellules présentant des phénotypes d'hépatocytes et de cellules souches d'hépatocytes, cellules produites par ces procédés et procédés pour l'utilisation des cellules
KR101644534B1 (ko) 2009-05-01 2016-08-01 비미니 테크놀로지스 엘엘씨 조직 및 세포 부유화 이식편의 최적화 시스템, 방법 및 조성물
US20120282228A1 (en) * 2009-07-15 2012-11-08 Vishal Bhasin Method of producing progenitor cells from differentiated cells
JP6243119B2 (ja) * 2009-07-21 2017-12-06 エイビーティー ホールディング カンパニー 白血球溢出を低下させる幹細胞の使用
CA2768573C (fr) * 2009-07-21 2020-09-15 Abt Holding Company Une methode de construction d'une banque de cellules et une methode de decouverte de medicament
US20110027239A1 (en) * 2009-07-29 2011-02-03 Tissue Genesis, Inc. Adipose-derived stromal cells (asc) as delivery tool for treatment of cancer
EP2467149B1 (fr) * 2009-08-17 2018-04-04 Ashok K. Singh Fluide provenant de la peau et de l'épiploon pour une utilisation médicale
AU2010322808B9 (en) 2009-11-30 2014-08-07 Pluri Biotech Ltd Adherent cells from placenta and use of same in disease treatment
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (fr) * 2010-02-25 2011-09-01 Abt Holding Company Modulation de l'activation des microglies
US9447379B2 (en) 2010-02-27 2016-09-20 Reza Izadpanah Derivation of hematopoietic cells from adult mesenchymal stem cells
SG10201913920PA (en) 2010-05-12 2020-03-30 Abt Holding Co Modulation of splenocytes in cell therapy
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
WO2011158125A2 (fr) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Procédé de différenciation de cellules en cellules étoilées du foie et en cellules endothéliales sinusoïdales du foie, cellules produites par ces procédés, et procédés d'utilisation des cellules
US9296984B2 (en) 2010-07-09 2016-03-29 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue
EP3366327B1 (fr) 2010-07-09 2022-09-21 GID BIO, Inc. Appareil et procédés relatifs à la collecte et au traitement d'un matériel biologique humain contenant des cellules adipeuses
US9206387B2 (en) 2010-07-09 2015-12-08 The Gid Group, Inc. Method and apparatus for processing adipose tissue
WO2013106655A1 (fr) 2012-01-11 2013-07-18 The Gid Group, Inc. Procédé de traitement de tissu adipeux et appareil de traitement
SG177238A1 (en) * 2010-07-22 2012-03-29 Affiliated Hospital Of Ningxia Medical University A method of producing neurons from stem cells, the neurons and uses thereof
AU2011293440B2 (en) 2010-08-24 2016-05-05 Katholieke Universiteit Leuven Non-static suspension culture of cell aggregates
JP5804342B2 (ja) * 2010-09-11 2015-11-04 国立大学法人金沢大学 脂肪組織由来間質細胞群を含む肝炎治療剤
WO2012048298A2 (fr) 2010-10-08 2012-04-12 Caridianbct, Inc. Procédés et systèmes de culture et de récolte de cellules dans un système de bioréacteur à fibres creuses avec conditions de régulation
CA2823123A1 (fr) * 2010-12-27 2012-07-05 Intellicell Biosciences, Inc. Extraits vasculaires de stroma et de mesenchyme derives par cavitation ultrasonique et cellules derivees de ceux-ci obtenues a partir de tissu adipeux et utilisation de ceux-ci
KR101903339B1 (ko) 2011-03-22 2018-10-01 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법
WO2012140519A2 (fr) 2011-04-15 2012-10-18 Pluristem Ltd. Procédés et systèmes de récolte de cellules
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
CN102433299B (zh) * 2011-11-17 2013-01-23 安徽农业大学 小鼠脂肪干细胞的分离、培养及纯化方法
US9512405B2 (en) 2011-12-14 2016-12-06 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Non-enzymatic method for isolating human adipose-derived stromal stem cells
US8940317B2 (en) 2011-12-23 2015-01-27 Pioneer Surgical Technology Continuous matrix with osteoconductive particles dispersed therein, method of forming thereof, and method of regenerating bone therewith
KR101921787B1 (ko) 2012-09-04 2018-11-23 플루리스템 리미티드 자간전증의 예방 및 치료 방법
EP3075841B1 (fr) 2012-09-06 2021-03-10 GID BIO, Inc. Appareil de traitement de tissus et procédé de traitement de tissu adipeux
WO2014089554A1 (fr) * 2012-12-07 2014-06-12 Antria, Inc. Formulations contenant des cellules souches adipeuses, trousse pour utiliser de telles cellules et leur utilisation
US9650608B2 (en) 2013-02-22 2017-05-16 Medivet America, Llc Activating adipose-derived stem cells for transplantation
US9861660B2 (en) 2013-04-12 2018-01-09 Saverio LaFrancesca Organs for transplantation
JP2016519939A (ja) 2013-05-22 2016-07-11 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ 多能性ヒト脂肪成体幹細胞：単離、キャラクタリゼーションおよび臨床的意味
EP3027235A1 (fr) 2013-07-30 2016-06-08 Musculoskeletal Transplant Foundation Matrices dérivées de tissu mou acellulaire et leurs procédés de préparation
US20150037303A1 (en) * 2013-08-01 2015-02-05 Regen Biopharma, Inc Cells, compositions, and treatment methods for stimulation of hematopoiesis
WO2015035221A1 (fr) 2013-09-05 2015-03-12 The Gid Group, Inc. Appareil de traitement de tissu et procédé de traitement de tissu adipeux
EP3068867B1 (fr) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expansion de cellules dans un bioréacteur
WO2015148704A1 (fr) 2014-03-25 2015-10-01 Terumo Bct, Inc. Remplacement passif de milieu
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
US10258652B2 (en) 2014-12-18 2019-04-16 Pluristem Ltd. Methods and compositions for treating and preventing muscle wasting disorders
WO2016151476A1 (fr) 2015-03-23 2016-09-29 Pluristem Ltd. Utilisation de cellules stromales adhérentes pour améliorer l'hématopoïèse chez un sujet en attente d'un tel traitement
CA3177726A1 (fr) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Fibres osseuses corticales demineralisees modifiees
WO2017004592A1 (fr) 2015-07-02 2017-01-05 Terumo Bct, Inc. Croissance cellulaire à l'aide de stimuli mécaniques
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
EP3405566B1 (fr) 2016-01-21 2023-10-18 ABT Holding Company Cellules souches pour la cicatrisation des ulcères de la peau
IL261146B (en) 2016-02-18 2022-07-01 Pluristem Ltd Methods and compounds for the treatment of cancerous tumors and malignancies
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
BR112019003871A2 (pt) 2016-08-30 2019-07-16 Lifecell Corp sistemas e métodos para controle de dispositivo médico
USD851777S1 (en) 2017-01-30 2019-06-18 Lifecell Corporation Canister-type device for tissue processing
WO2018184028A2 (fr) 2017-03-31 2018-10-04 Terumo Bct, Inc. Expansion cellulaire
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
CN106834259A (zh) * 2017-04-14 2017-06-13 青岛青春派生物科技有限公司 一种人脂肪组织消化酶及其制备方法
WO2018198012A1 (fr) 2017-04-24 2018-11-01 Pluristem Ltd. Méthodes et compositions pour traiter des troubles neurologiques
EP3655518A4 (fr) 2017-07-18 2021-07-14 GID Bio, Inc. Système de digestion de tissu adipeux et procédé de traitement de tissu
JP2024511064A (ja) 2021-03-23 2024-03-12 テルモ ビーシーティー、インコーポレーテッド 細胞捕獲及び増殖

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902741A (en) 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US5863531A (en) 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5804178A (en) 1986-11-20 1998-09-08 Massachusetts Institute Of Technology Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue
US5041138A (en) 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US5736372A (en) 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
CA1340581C (fr) 1986-11-20 1999-06-08 Joseph P. Vacanti Neomorphogenese chimerique d'organes par implatation cellulaire controlee, utilisant des matrices artificielles
IL95429A (en) 1989-09-15 1997-09-30 Organogenesis Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production
NO171069C (no) 1990-05-29 1993-01-20 Protan Biopolymer As Kovalent tverrbundne, sterkt svellende alkalimetall- og ammonium-alginatgeler, samt fremgangsmaate for fremstilling derav
US5811094A (en) 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
AU4543193A (en) 1992-06-22 1994-01-24 Henry E. Young Scar inhibitory factor and use thereof
US5709854A (en) 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US6176874B1 (en) 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US5723331A (en) 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
US6103522A (en) 1994-07-20 2000-08-15 Fred Hutchinson Cancer Research Center Human marrow stromal cell lines which sustain hematopoiesis
US5516532A (en) 1994-08-05 1996-05-14 Children's Medical Center Corporation Injectable non-immunogenic cartilage and bone preparation
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US6653134B2 (en) 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US6123727A (en) 1995-05-01 2000-09-26 Massachusetts Institute Of Technology Tissue engineered tendons and ligaments
US5855610A (en) 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US5741685A (en) 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
EP0801676A2 (fr) 1995-10-20 1997-10-22 Michael Sittinger Nouveaux tissus artificiels, procede de fabrication correspondant et utilisation
ATE258810T1 (de) 1995-11-09 2004-02-15 Univ Massachusetts Wiederherstellung der gewebeoberfläche mit zusammensetzungen aus hydrogel-zellen
PT868505E (pt) 1995-11-16 2005-06-30 Univ Case Western Reserve Inducao condrogenica in vitro de celulas estaminais mesenquimais humanas
US6200606B1 (en) 1996-01-16 2001-03-13 Depuy Orthopaedics, Inc. Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration
EP0941027A4 (fr) 1996-11-15 2000-08-09 Osiris Therapeutics Inc Compositions mixtes de cellules MSC et de précurseurs de mégacaryocytes et procédé pour isoler les cellules MSC associées aux mégacaryocytes, en séparant les Mégacaryocytes
US5786207A (en) 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
DE69841850D1 (de) 1997-12-02 2010-09-30 Artecel Sciences Inc Differenzierung in osteoblasten der fettgewebe-stromalen zellen und ihre verwendungen
US6027744A (en) 1998-04-24 2000-02-22 University Of Massachusetts Medical Center Guided development and support of hydrogel-cell compositions
IL139601A0 (en) * 1998-05-26 2002-02-10 Genitrix Llc Compositions and methods of modulating an immune response to an antigen
AU4221399A (en) 1998-05-29 1999-12-13 Osiris Therapeutics, Inc. Human cd45+ and/or fibroblast + mesenchymal stem cells
AU4336599A (en) 1998-06-08 1999-12-30 Osiris Therapeutics, Inc. (in vitro) maintenance of hematopoietic stem cells
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
KR100979664B1 (ko) 1999-03-10 2010-09-02 유니버시티 오브 피츠버그 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 지방 유래 간세포 및 격자
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6555374B1 (en) * 1999-08-19 2003-04-29 Artecel Sciences, Inc. Multiple mesodermal lineage differentiation potentials for adipose tissue-derived stromal cells and uses thereof
WO2001021767A2 (fr) 1999-09-24 2001-03-29 Morphogen Pharmaceuticals, Inc. Cellules souches embryonnaires totipotentes
ATE384124T1 (de) * 2000-02-26 2008-02-15 Artecel Inc Pluripotente stammzellen erzeugt aus stromalzellen aus dem fettgewebe und deren verwendungen
EP1152058A1 (fr) * 2000-05-03 2001-11-07 Institut Curie Méthodes et compositions permettant d'effectuer la recombinaison homologue

Also Published As

Publication number Publication date
WO2001062901A3 (fr) 2002-02-21
EP1261694B1 (fr) 2008-01-16
ES2300320T3 (es) 2008-06-16
EP1261694A2 (fr) 2002-12-04
SG134168A1 (en) 2007-08-29
JP2003523767A (ja) 2003-08-12
US20010033834A1 (en) 2001-10-25
PT1261694E (pt) 2008-04-03
ATE384124T1 (de) 2008-02-15
US7078230B2 (en) 2006-07-18
CA2400485C (fr) 2014-04-29
US20060228341A1 (en) 2006-10-12
WO2001062901A2 (fr) 2001-08-30
DE60132429T2 (de) 2009-01-08
CA2400485A1 (fr) 2001-08-30
IL151228A (en) 2013-05-30
DE60132429D1 (de) 2008-03-06
AU2001238695B2 (en) 2005-11-24
AU3869501A (en) 2001-09-03

Similar Documents

Publication Publication Date Title
DK1261694T3 (da) Pluripotente stamceller som er genereret ud fra stromaceller der er afledt af adipöst væv samt anvendelser deraf
CY1116198T1 (el) Ταυτοποιηση και απομονωση πολυδυναμων κυτταρων απο μη-οστεοχονδρινο μεσεγχυματικο ιστο
CO2019002569A2 (es) Método para aislar células madre mesenquimales a partir de membrana amniótica de cordón umbilical utilizando un medio de cultivo celular
WO2005047524A3 (fr) Compositions et procedes pour induire la differenciation cellulaire
ATE408667T1 (de) Identifizierung pluripotenter prämesenchymaler, prähämotopoietischer vorläuferzellen
DK1230375T3 (da) Inhibering af genekspression med dsRNA
DK1379671T3 (da) Fremgangsmåder til dyrkning af circovirus
MXPA04009031A (es) Celulas madre hepaticas primitivas y proximales.
BR0109763A (pt) Conjuntos de fontes sìsmicas
DK0891420T3 (da) Fremgangsmåde til replikation af influenzavirus i cellekultur samt de ved fremgangsmåden opnåelige influenzavirus
DK1290444T3 (da) Toxicitetstypisering under anvendelse af lever-stamceller
IL150789A0 (en) Multipotent neural stem cells from peripheral tissues and uses thereof
ATE498011T1 (de) Modifizierte embryonale stammzellen und embryonales stammzellspezifisches gen
PE20130213A1 (es) Marcadores predictivos utiles en el tratamiento del sindrome fragil x (fxs)
BR0015264A (pt) Uso de genomas haplóides para diagnóstico, modificação e multiplicação genética
DK1292320T3 (da) Anvendelse af ekstrakter med immunmodulerende aktivitet fra spermatofytplanter
MX2021010739A (es) Celulas madre mesenquimales inmunomoduladoras.
ATE519839T1 (de) Verfahren zur differenzierung von stammzellen
AR022583A1 (es) Secuencias antitumorales anti-sentido dirigidas contra los componentes r1 y r2 de la reductasa de los ribonucleotidos
EP1814994A4 (fr) Appareil et système comprenant des compositions sèches d'extinction génique
NO331018B1 (no) In vitro fremgangsmate ved bestemmelse av pre-neoplastiske og/eller neoplastiske tilstander hos pattedyr ved purinergisk reseptorekspresjon, samt anvendelse og sett for slik pavisning
PH12020551584A1 (en) Stem/progenitor cells from duodenal brunner's glands and methods of isolating and using them
DE602005015868D1 (de) Modulation der anzahl von pflanzenzellen
TW200643169A (en) The preparation of multipotent stem cells and the use thereof
WO2003083057A3 (fr) Adipocytes et leurs utilisations