DK1221444T3 - Kondenserede imidazolforbindelser og lægemidler mod diabetes mellitus - Google Patents

Kondenserede imidazolforbindelser og lægemidler mod diabetes mellitus

Info

Publication number
DK1221444T3
DK1221444T3 DK00940909T DK00940909T DK1221444T3 DK 1221444 T3 DK1221444 T3 DK 1221444T3 DK 00940909 T DK00940909 T DK 00940909T DK 00940909 T DK00940909 T DK 00940909T DK 1221444 T3 DK1221444 T3 DK 1221444T3
Authority
DK
Denmark
Prior art keywords
group
diabetes mellitus
alkyl group
adenosine
condensed imidazole
Prior art date
Application number
DK00940909T
Other languages
English (en)
Inventor
Seiichi Kobayashi
Osamu Asano
Hitoshi Harada
Seiji Yoshikawa
Nobuhisa Watanabe
Takashi Inoue
Tatsuo Horizoe
Nobuyuki Yasuda
Kaya Ohashi
Hiroe Minami
Junsaku Nagaoka
Manabu Murakami
Isao Tanaka
Tsutomu Kawata
Naoyuki Shimomura
Hiroshi Akamatsu
Naoki Ozeki
Toshikazu Shimizu
Kenji Hayashi
Toyokazu Haga
Shigeto Negi
Toshihiko Naito
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DK1221444T3 publication Critical patent/DK1221444T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
DK00940909T 1999-07-02 2000-06-30 Kondenserede imidazolforbindelser og lægemidler mod diabetes mellitus DK1221444T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18848499 1999-07-02
JP2000143495 2000-05-16
JP2000182786 2000-06-19

Publications (1)

Publication Number Publication Date
DK1221444T3 true DK1221444T3 (da) 2005-11-14

Family

ID=27326046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00940909T DK1221444T3 (da) 1999-07-02 2000-06-30 Kondenserede imidazolforbindelser og lægemidler mod diabetes mellitus

Country Status (14)

Country Link
US (1) US6841549B1 (da)
EP (1) EP1221444B1 (da)
JP (1) JP4324338B2 (da)
KR (1) KR100694684B1 (da)
CN (1) CN1166666C (da)
AT (1) ATE303387T1 (da)
AU (1) AU778450B2 (da)
CA (1) CA2376835C (da)
DE (1) DE60022366T2 (da)
DK (1) DK1221444T3 (da)
ES (1) ES2246867T3 (da)
NZ (1) NZ516260A (da)
PT (1) PT1221444E (da)
WO (1) WO2001002400A1 (da)

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Also Published As

Publication number Publication date
AU5571700A (en) 2001-01-22
DE60022366D1 (de) 2005-10-06
EP1221444B1 (en) 2005-08-31
EP1221444A1 (en) 2002-07-10
WO2001002400A1 (fr) 2001-01-11
KR100694684B1 (ko) 2007-03-13
AU778450B2 (en) 2004-12-09
US6841549B1 (en) 2005-01-11
CA2376835A1 (en) 2001-01-11
EP1221444A4 (en) 2003-05-07
ATE303387T1 (de) 2005-09-15
CA2376835C (en) 2009-09-15
JP4324338B2 (ja) 2009-09-02
ES2246867T3 (es) 2006-03-01
PT1221444E (pt) 2005-11-30
NZ516260A (en) 2004-08-27
WO2001002400A8 (fr) 2001-04-05
CN1166666C (zh) 2004-09-15
KR20020015060A (ko) 2002-02-27
CN1365361A (zh) 2002-08-21
DE60022366T2 (de) 2006-06-14

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