DK1189929T3 - Faktor VIIa-inhibitorer - Google Patents

Faktor VIIa-inhibitorer

Info

Publication number
DK1189929T3
DK1189929T3 DK00938691T DK00938691T DK1189929T3 DK 1189929 T3 DK1189929 T3 DK 1189929T3 DK 00938691 T DK00938691 T DK 00938691T DK 00938691 T DK00938691 T DK 00938691T DK 1189929 T3 DK1189929 T3 DK 1189929T3
Authority
DK
Denmark
Prior art keywords
factor viia
viia inhibitors
inhibitors
factor
viia
Prior art date
Application number
DK00938691T
Other languages
Danish (da)
English (en)
Inventor
Otmar Klingler
Manfred Schudok
Gerhard Zoller
Uwe Heinelt
Elisabeth Defossa
Hans Matter
Pavel Safar
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK1189929T3 publication Critical patent/DK1189929T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK00938691T 1999-06-08 2000-05-27 Faktor VIIa-inhibitorer DK1189929T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99111109A EP1059302A1 (fr) 1999-06-08 1999-06-08 Inhibiteurs de factor VIIa
PCT/EP2000/004846 WO2000075172A2 (fr) 1999-06-08 2000-05-27 INHIBITEURS DU FACTEUR VIIa

Publications (1)

Publication Number Publication Date
DK1189929T3 true DK1189929T3 (da) 2003-11-24

Family

ID=8238315

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00938691T DK1189929T3 (da) 1999-06-08 2000-05-27 Faktor VIIa-inhibitorer

Country Status (32)

Country Link
US (1) US6500803B1 (fr)
EP (2) EP1059302A1 (fr)
JP (1) JP4546683B2 (fr)
KR (1) KR100979069B1 (fr)
CN (1) CN1359390B (fr)
AR (1) AR024292A1 (fr)
AT (1) ATE246707T1 (fr)
AU (1) AU774037B2 (fr)
BR (1) BR0011461A (fr)
CA (1) CA2376064C (fr)
CZ (1) CZ300365B6 (fr)
DE (1) DE60004363T2 (fr)
DK (1) DK1189929T3 (fr)
EE (1) EE04855B1 (fr)
ES (1) ES2202137T3 (fr)
HK (1) HK1047289B (fr)
HR (1) HRP20010912B1 (fr)
HU (1) HUP0201451A3 (fr)
IL (2) IL146731A0 (fr)
ME (1) MEP57708A (fr)
MX (1) MXPA01012568A (fr)
NO (1) NO328249B1 (fr)
NZ (1) NZ515966A (fr)
PL (1) PL202879B1 (fr)
PT (1) PT1189929E (fr)
RS (1) RS50415B (fr)
RU (1) RU2248359C2 (fr)
SI (1) SI1189929T1 (fr)
SK (1) SK286902B6 (fr)
TR (1) TR200103550T2 (fr)
WO (1) WO2000075172A2 (fr)
ZA (1) ZA200110053B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1059302A1 (fr) * 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Inhibiteurs de factor VIIa
DE10005631A1 (de) * 2000-02-09 2001-08-23 Max Planck Gesellschaft Arginin-Mimetika als Faktor X¶a¶-Inhibitoren
GB0014134D0 (en) * 2000-06-10 2000-08-02 Astrazeneca Ab Combination therapy
EP1364960A4 (fr) * 2001-02-02 2005-05-18 Chugai Pharmaceutical Co Ltd Derives de peptide
GB0127615D0 (en) * 2001-07-09 2002-01-09 Aventis Pharm Prod Inc Substituted amides, sulfonamides and ureas useful for inhibiting kinase activity
WO2005016900A1 (fr) 2003-08-18 2005-02-24 H. Lundbeck A/S Sel de succinate et de malonate de trans-4-((1r,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine et son utilisation en tant que medicament
TWI376373B (en) 2005-02-16 2012-11-11 Lundbeck & Co As H Crystalline base of a pharmaceutical compound
TWI453198B (zh) 2005-02-16 2014-09-21 Lundbeck & Co As H 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s）-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法
ATE455103T1 (de) * 2005-06-24 2010-01-15 Bristol Myers Squibb Co Als antikoagulationsmittel geeignete phenylglycinamid- und pyridylglycinamidderivate
WO2007131996A1 (fr) * 2006-05-12 2007-11-22 Genmedica Therapeutics Sl Sels de vanadate de méta-xylylène diamine
SI3464336T1 (sl) 2016-06-01 2022-06-30 Athira Pharma, Inc. Spojine
US20220380478A1 (en) 2019-07-01 2022-12-01 Tonix Pharma Holdings Limited Anti-cd154 antibodies and uses thereof
MX2023008055A (es) 2021-01-06 2023-08-22 Tonix Pharma Ltd Métodos para inducir tolerancia inmune con anticuerpos anti-cd154 modificados.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
US5506134A (en) 1990-10-22 1996-04-09 Corvas International, Inc. Hypridoma and monoclonal antibody which inhibits blood coagulation tissue factor/factor VIIa complex
US5833982A (en) 1991-02-28 1998-11-10 Zymogenetics, Inc. Modified factor VII
US5788965A (en) 1991-02-28 1998-08-04 Novo Nordisk A/S Modified factor VII
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
ZA953361B (en) * 1994-04-26 1996-01-12 Selectide Corp Factor Xa inhibitors
AU2056197A (en) * 1996-02-22 1997-09-10 Du Pont Merck Pharmaceutical Company, The M-amidino phenyl analogs as factor xa inhibitors
AR013084A1 (es) * 1997-06-19 2000-12-13 Astrazeneca Ab Derivados de amidino utiles como inhibidores de la trombina, composicion farmaceutica, utilizacion de dichos compuestos para la preparacion demedicamentos y proceso para la preparacion de los compuestos mencionados
EP0987274A1 (fr) * 1998-09-15 2000-03-22 Hoechst Marion Roussel Deutschland GmbH Inhibiteurs du facteur VIIa
EP1059302A1 (fr) * 1999-06-08 2000-12-13 Aventis Pharma Deutschland GmbH Inhibiteurs de factor VIIa

Also Published As

Publication number Publication date
CZ300365B6 (cs) 2009-04-29
CZ20014357A3 (cs) 2002-03-13
JP4546683B2 (ja) 2010-09-15
TR200103550T2 (tr) 2002-05-21
PL202879B1 (pl) 2009-07-31
HK1047289A1 (en) 2003-02-14
CA2376064C (fr) 2011-04-26
MEP57708A (en) 2011-05-10
WO2000075172A3 (fr) 2001-05-31
HRP20010912B1 (en) 2010-10-31
KR20020020728A (ko) 2002-03-15
SK17592001A3 (sk) 2002-05-09
CA2376064A1 (fr) 2000-12-14
EE200100662A (et) 2003-04-15
US6500803B1 (en) 2002-12-31
EP1189929A2 (fr) 2002-03-27
HK1047289B (zh) 2010-10-22
ES2202137T3 (es) 2004-04-01
SI1189929T1 (en) 2004-02-29
JP2003502294A (ja) 2003-01-21
YU86101A (sh) 2004-07-15
RS50415B (sr) 2009-12-31
NZ515966A (en) 2003-09-26
EE04855B1 (et) 2007-06-15
DE60004363D1 (de) 2003-09-11
HRP20010912A2 (en) 2003-04-30
ATE246707T1 (de) 2003-08-15
EP1059302A1 (fr) 2000-12-13
AR024292A1 (es) 2002-09-25
BR0011461A (pt) 2002-03-19
HUP0201451A3 (en) 2003-08-28
MXPA01012568A (es) 2002-04-10
IL146731A (en) 2007-07-24
PL352200A1 (en) 2003-08-11
NO20016005D0 (no) 2001-12-07
AU774037B2 (en) 2004-06-17
IL146731A0 (en) 2002-07-25
EP1189929B1 (fr) 2003-08-06
SK286902B6 (sk) 2009-07-06
AU5397600A (en) 2000-12-28
KR100979069B1 (ko) 2010-08-31
DE60004363T2 (de) 2004-06-24
CN1359390A (zh) 2002-07-17
HUP0201451A2 (en) 2002-08-28
NO328249B1 (no) 2010-01-18
ZA200110053B (en) 2002-07-03
WO2000075172A2 (fr) 2000-12-14
CN1359390B (zh) 2010-05-26
PT1189929E (pt) 2003-12-31
RU2248359C2 (ru) 2005-03-20
NO20016005L (no) 2002-02-06

Similar Documents

Publication Publication Date Title
NO20011293D0 (no) Faktor VIIa-inhibitorer
NO20021230L (no) Faktor Xa inhibitorer
PT1181017E (pt) Inibidores de metaloproteases
DE60014610D1 (de) Glukokinase aktivatoren
NO20022863L (no) Trans-olefiniske glycokinase aktivatorer
NO20001687D0 (no) Benzamidinderivater som faktor Xa-inhibitorer
PT1224195E (pt) C-aril-glicosidos inibidores de tgls2
NO20013072L (no) Nitrogenholdige heterocykler som faktor Xa-inhibitorer
NO20003808L (no) Substituerte oksoazaheterosyklylfaktor Xa inhibitorer
DE60017180D1 (de) Fab i inhibitoren
PT1194404E (pt) Inibidores de aspartil-protease
ATE246707T1 (de) Faktor viia inhibitore
DE60003212D1 (de) Druckkopf
ATE252547T1 (de) Matrixmetalloproteinaseinhibitoren
DE60206376D1 (de) Faktor xa inhibitor
DE60037785D1 (de) Wellenformentzerrer
DE60008319D1 (de) IL-12 Produktionsinhibitor
SE9900233D0 (sv) Navigationsinstrument
SE9902851D0 (sv) Dammsugarmunstycke
SE9901990D0 (sv) Dammsugarmunstycke
FI990517A0 (fi) Suutin
DK199901689A (da) Coating
SE9903473D0 (sv) Quercetin m m