DE60206376D1 - Faktor xa inhibitor - Google Patents

Faktor xa inhibitor

Info

Publication number
DE60206376D1
DE60206376D1 DE60206376T DE60206376T DE60206376D1 DE 60206376 D1 DE60206376 D1 DE 60206376D1 DE 60206376 T DE60206376 T DE 60206376T DE 60206376 T DE60206376 T DE 60206376T DE 60206376 D1 DE60206376 D1 DE 60206376D1
Authority
DE
Germany
Prior art keywords
inhibitor
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60206376T
Other languages
English (en)
Other versions
DE60206376T2 (de
Inventor
Lowell Engel
Alan Diseroad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2001/002553 external-priority patent/WO2001096323A1/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE60206376D1 publication Critical patent/DE60206376D1/de
Application granted granted Critical
Publication of DE60206376T2 publication Critical patent/DE60206376T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60206376T 2001-06-12 2002-06-06 Faktor xa inhibitor Expired - Fee Related DE60206376T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/GB2001/002553 WO2001096323A1 (en) 2000-06-13 2001-06-12 Serine protease inhibitors
WOPCT/GB01/02553 2001-06-12
US33929501P 2001-12-12 2001-12-12
US339295P 2001-12-12
PCT/US2002/016569 WO2002100847A2 (en) 2001-06-12 2002-06-06 Factor xa inhibitor

Publications (2)

Publication Number Publication Date
DE60206376D1 true DE60206376D1 (de) 2006-02-09
DE60206376T2 DE60206376T2 (de) 2006-06-22

Family

ID=41210812

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60206376T Expired - Fee Related DE60206376T2 (de) 2001-06-12 2002-06-06 Faktor xa inhibitor

Country Status (13)

Country Link
US (1) US20040162295A1 (de)
EP (1) EP1397348B1 (de)
JP (1) JP2004534062A (de)
AR (1) AR036048A1 (de)
AT (1) ATE305452T1 (de)
AU (1) AU2002348501A1 (de)
DE (1) DE60206376T2 (de)
ES (1) ES2248618T3 (de)
MY (1) MY137876A (de)
PE (1) PE20030198A1 (de)
SV (1) SV2003001085A (de)
TW (1) TWI257389B (de)
WO (1) WO2002100847A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE384713T1 (de) 2001-07-26 2008-02-15 Lilly Co Eli 1-glycinyl-4-(1-methylpiperidin-4-yl)piperazine und -piperidine als faktor-xa-antagonisten
CN1288135C (zh) 2002-04-01 2006-12-06 伊莱利利公司 某些作为丝氨酸蛋白酶xa因子抑制剂的1－(d－环丙基甘氨酰基)－4－(哌啶－4－基)哌嗪化合物
BRPI0512245A (pt) * 2004-06-30 2008-02-19 Lilly Co Eli composto, composição farmacêutica, e, uso do composto
KR100849242B1 (ko) * 2004-06-30 2008-07-29 일라이 릴리 앤드 캄파니 1(인돌-6-카르보닐-ｄ-페닐글리시닐)-4-(1-메틸피페리딘-4-일) 피페라진 ｄ-타르트레이트
DE102007028407A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028406A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
EP2875020B1 (de) * 2012-07-19 2017-09-06 Boehringer Ingelheim International GmbH Verfahren zur herstellung von einem fumarsäuresalz von 9- [4- (3-chlor-2-fluor-phenylamino)-7-methoxy-chinazolin-6-yloxy]-1,4-diaza-spiro[5.5]undecan-5-on

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1192132B1 (de) * 1999-06-14 2005-09-07 Eli Lilly And Company Inhibitoren von serin proteasen
GB0030304D0 (en) * 2000-12-13 2001-01-24 Lilly Co Eli Compounds

Also Published As

Publication number Publication date
PE20030198A1 (es) 2003-03-12
JP2004534062A (ja) 2004-11-11
ES2248618T3 (es) 2006-03-16
EP1397348A2 (de) 2004-03-17
MY137876A (en) 2009-03-31
SV2003001085A (es) 2003-03-18
DE60206376T2 (de) 2006-06-22
US20040162295A1 (en) 2004-08-19
EP1397348B1 (de) 2005-09-28
AR036048A1 (es) 2004-08-04
AU2002348501A1 (en) 2002-12-23
WO2002100847A2 (en) 2002-12-19
ATE305452T1 (de) 2005-10-15
TWI257389B (en) 2006-07-01
WO2002100847A3 (en) 2003-08-21

Similar Documents

Publication Publication Date Title
NO20042592L (no) Indol-2-karboksamider som faktor XA inhibitorer
NO20021230L (no) Faktor Xa inhibitorer
AU2002350217A8 (en) Glycinamides as factor xa inhibitors
CY2015028I2 (el) Ενας αναστολεας ν-ακυλοσφιγγοσινο γλυκοζυλοτρανσφερασης
NO20041163L (no) Laktam-inneholdende forbindelser og derivater derav som faktor XA-inhibitorer
DE60234125D1 (de) E inhibitoren
IS7016A (is) Ný 4-anilínókínólín-3-karboxamíð
IL169323A0 (en) Pyrazole-derivatives as factor xa inhibitors
AU2002365896A8 (en) Substituted amino methyl factor xa inhibitors
DE60217588D1 (de) Verdichterbeschichtung
NO20042990L (no) Pyrrolidin-2-oner som faktor XA inhibitorer
DK1395553T3 (da) Pyrrolidinderivater som faktor Xa-inhibitorer
DK1189929T3 (da) Faktor VIIa-inhibitorer
ATE305452T1 (de) Faktor xa inhibitor
ATA8182001A (de) Fluorometer
NO20013535L (no) Nöytrofil-funksjons-inhibitorer
NO20015983D0 (no) Sangmikrofon
DE60223839D1 (de) Gipskartonplatte
DE60203837D1 (de) Verdichterbeschichtung
DE60206558D1 (de) Beschichtung
NO20015984D0 (no) Sangmikrofon
DE50214718D1 (de) Montagewinkel
SE0102987D0 (sv) Länsa
DK1357966T3 (da) Dispenser
FI20010089A (fi) Veneen pohja

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee