DK1183253T3 - C7-ester-substituerede taxaner som antitumormidler - Google Patents
C7-ester-substituerede taxaner som antitumormidlerInfo
- Publication number
- DK1183253T3 DK1183253T3 DK01905349T DK01905349T DK1183253T3 DK 1183253 T3 DK1183253 T3 DK 1183253T3 DK 01905349 T DK01905349 T DK 01905349T DK 01905349 T DK01905349 T DK 01905349T DK 1183253 T3 DK1183253 T3 DK 1183253T3
- Authority
- DK
- Denmark
- Prior art keywords
- ester
- antitumor agents
- substituted taxanes
- taxanes
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17979400P | 2000-02-02 | 2000-02-02 | |
PCT/US2001/003385 WO2001057027A1 (en) | 2000-02-02 | 2001-02-02 | C7 ester substituted taxanes as antitumor agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1183253T3 true DK1183253T3 (da) | 2008-09-22 |
Family
ID=22658029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01905349T DK1183253T3 (da) | 2000-02-02 | 2001-02-02 | C7-ester-substituerede taxaner som antitumormidler |
Country Status (35)
Country | Link |
---|---|
US (3) | US6610860B2 (ru) |
EP (1) | EP1183253B8 (ru) |
JP (1) | JP2003522167A (ru) |
KR (1) | KR100784161B1 (ru) |
CN (1) | CN1362955A (ru) |
AR (1) | AR030188A1 (ru) |
AT (1) | ATE396188T1 (ru) |
AU (1) | AU776051B2 (ru) |
BG (1) | BG65279B1 (ru) |
BR (1) | BR0104749A (ru) |
CA (1) | CA2368993C (ru) |
CO (1) | CO5280224A1 (ru) |
CZ (1) | CZ298484B6 (ru) |
DE (1) | DE60134094D1 (ru) |
DK (1) | DK1183253T3 (ru) |
ES (1) | ES2307588T3 (ru) |
GE (1) | GEP20043322B (ru) |
HK (1) | HK1047938A1 (ru) |
HU (1) | HUP0200917A3 (ru) |
IL (1) | IL145641A0 (ru) |
MX (1) | MXPA01009901A (ru) |
MY (1) | MY137637A (ru) |
NO (1) | NO327982B1 (ru) |
NZ (1) | NZ514409A (ru) |
PL (1) | PL202668B1 (ru) |
PT (1) | PT1183253E (ru) |
RO (1) | RO121777B1 (ru) |
RU (1) | RU2265017C2 (ru) |
SA (1) | SA01220045B1 (ru) |
SK (1) | SK13712001A3 (ru) |
TR (1) | TR200102856T1 (ru) |
TW (1) | TWI291873B (ru) |
UA (1) | UA75573C2 (ru) |
WO (1) | WO2001057027A1 (ru) |
ZA (1) | ZA200108060B (ru) |
Families Citing this family (37)
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AR030188A1 (es) | 2000-02-02 | 2003-08-13 | Univ Florida State Res Found | Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos |
MXPA01009900A (es) * | 2000-02-02 | 2003-08-20 | Univ Florida State Res Found | Formulaciones de taxano que tienen solubilidad mejorada. |
CA2354486A1 (en) * | 2001-07-31 | 2003-01-31 | Florida State University Research Foundation, Inc. | C7 ester substituted taxanes |
KR100819578B1 (ko) * | 2001-08-01 | 2008-04-04 | 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 | C7 에스테르 치환된 탁산 |
SG125889A1 (en) * | 2001-08-01 | 2006-10-30 | Univ Florida State Res Found | C7 ester subsituted taxanes |
US20030082229A1 (en) * | 2001-11-01 | 2003-05-01 | Board Of Regents, The University Of Texas Systems | Parenteral chlorambucil for treatment of malignant and autoimmune disease and methods of use |
US8012950B2 (en) * | 2003-08-29 | 2011-09-06 | Wisconsin Alumni Research Foundation | Method to diagnose and treat degenerative joint disease |
CN1886400A (zh) | 2003-09-25 | 2006-12-27 | 泰普斯特医药公司 | 9,10-α,α-OH紫杉烷类似物及其制备方法 |
EP1894921A3 (en) * | 2003-09-25 | 2008-03-12 | Tapestry Pharmaceuticals, Inc. | 9, 10-Alpha, Alpha-Oh-Taxane analogs and methods for production thereof |
JP2007527432A (ja) | 2004-03-05 | 2007-09-27 | フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド | C7ラクチルオキシ置換タキサン |
TW200533339A (en) | 2004-03-16 | 2005-10-16 | Bristol Myers Squibb Co | Therapeutic synergy of anti-cancer compounds |
US20090004118A1 (en) * | 2004-10-07 | 2009-01-01 | Shuming Nie | Multifunctional Nanoparticle Conjugates And Their Use |
EP2336139A3 (en) | 2004-10-25 | 2012-01-04 | Dekk-Tec, Inc. | Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents |
US20060216767A1 (en) * | 2005-03-22 | 2006-09-28 | Saladax Biomedical Inc. | Docetaxel immunoassay |
PL217731B1 (pl) | 2006-06-01 | 2014-08-29 | Tomasz Byrski | Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi |
US11786504B2 (en) | 2006-09-28 | 2023-10-17 | Tapestry Pharmaceuticals, Inc. | Taxane analogs for the treatment of brain cancer |
WO2008106621A1 (en) | 2007-02-28 | 2008-09-04 | Tapestry Pharmaceuticals, Inc | Taxane analogs for the treatment of brain cancer |
US11873308B2 (en) | 2006-11-06 | 2024-01-16 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
WO2008121476A1 (en) | 2007-03-28 | 2008-10-09 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
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BRPI0916739A2 (pt) | 2008-07-31 | 2015-11-03 | Ziopharm Oncology Inc | síntese e formulações de sais de mostarda de isofosforamida e análogos dos mesmos |
EP2401285B1 (en) | 2009-02-24 | 2012-10-10 | Dekk-Tec, Inc. | Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents |
WO2010138686A1 (en) | 2009-05-29 | 2010-12-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mdri-inverse agents |
AU2011224241B2 (en) | 2010-03-10 | 2014-05-08 | Sri International | The use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas |
WO2012033601A1 (en) | 2010-08-20 | 2012-03-15 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Thiosemicarbazones with mdr1 - inverse activity |
CN107929733A (zh) | 2011-07-11 | 2018-04-20 | 美国政府(由卫生和人类服务部的部长所代表) | 光敏抗体‑荧光团缀合物 |
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AU2014331667B2 (en) | 2013-10-11 | 2019-08-22 | Biomed Valley Discoveries, Inc. | TEM8 antibodies and their use |
CN106470705B (zh) | 2014-08-08 | 2020-03-31 | 美国政府(由卫生和人类服务部的部长所代表) | 在体内和在体外的靶标的光控移除 |
WO2019099615A1 (en) | 2017-11-17 | 2019-05-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of copeptin to modulate the immune response and hematopoiesis, and stimulate bone growth |
AU2019253681A1 (en) | 2018-04-10 | 2020-10-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combination of near infrared photoimmunotherapy targeting cancer cells and host-immune activation |
EP3994173A1 (en) | 2019-07-02 | 2022-05-11 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Monoclonal antibodies that bind egfrviii and their use |
WO2021154705A1 (en) | 2020-01-27 | 2021-08-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Rab13 and net1 antisense oligonucleotides to treat metastatic cancer |
EP4284439A1 (en) | 2021-01-29 | 2023-12-06 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Near infrared photoimmunotherapy (nir-pit) combination therapy to treat cancer |
MX2023012608A (es) | 2021-04-30 | 2023-11-03 | Kalivir Immunotherapeutics Inc | Virus oncoliticos para la expresion modificada del mhc. |
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Family Cites Families (58)
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FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5321128A (en) * | 1988-09-06 | 1994-06-14 | Kabi Pharmacia Ab | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
US4960790A (en) | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
SE463189B (sv) | 1989-03-13 | 1990-10-22 | Eston Joensson | Preparat avsett att tillfoeras amalgamfyllningar i taender foer att daerigenom hindra eller minska avgaang av kvicksilver eller kvicksilveraanga |
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FR2679230B1 (fr) | 1991-07-16 | 1993-11-19 | Rhone Poulenc Rorer Sa | Nouveaux derives d'analogues du taxol, leur preparation et les compositions qui les contiennent. |
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JP2003502401A (ja) | 1999-06-21 | 2003-01-21 | ナプロ バイオセラピューティクス,インコーポレイテッド | C−2ヒドロキシル保護−n−アシル(2r,3s)−3−フェニルイソセリン活性化エステルおよびそれらの製造方法 |
WO2001025223A1 (en) | 1999-10-06 | 2001-04-12 | The Research Foundation Of State University Of New York | Stabilization of taxane-containing dispersed systems |
MXPA01009900A (es) * | 2000-02-02 | 2003-08-20 | Univ Florida State Res Found | Formulaciones de taxano que tienen solubilidad mejorada. |
HUP0200995A3 (en) | 2000-02-02 | 2005-02-28 | Univ Florida State Res Found | Taxane formulations having improved solubility |
AR030188A1 (es) * | 2000-02-02 | 2003-08-13 | Univ Florida State Res Found | Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos |
IT1319168B1 (it) | 2000-03-17 | 2003-09-26 | Indena Spa | Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono. |
-
2001
- 2001-01-31 AR ARP010100463A patent/AR030188A1/es not_active Application Discontinuation
- 2001-01-31 CO CO01007075A patent/CO5280224A1/es not_active Application Discontinuation
- 2001-02-02 DK DK01905349T patent/DK1183253T3/da active
- 2001-02-02 TR TR2001/02856T patent/TR200102856T1/xx unknown
- 2001-02-02 GE GE4514A patent/GEP20043322B/en unknown
- 2001-02-02 SK SK1371-2001A patent/SK13712001A3/sk unknown
- 2001-02-02 IL IL14564101A patent/IL145641A0/xx unknown
- 2001-02-02 UA UA2001106734A patent/UA75573C2/uk unknown
- 2001-02-02 CA CA002368993A patent/CA2368993C/en not_active Expired - Fee Related
- 2001-02-02 US US09/775,851 patent/US6610860B2/en not_active Expired - Fee Related
- 2001-02-02 PL PL350026A patent/PL202668B1/pl not_active IP Right Cessation
- 2001-02-02 DE DE60134094T patent/DE60134094D1/de not_active Expired - Fee Related
- 2001-02-02 NZ NZ514409A patent/NZ514409A/xx unknown
- 2001-02-02 AT AT01905349T patent/ATE396188T1/de not_active IP Right Cessation
- 2001-02-02 HU HU0200917A patent/HUP0200917A3/hu unknown
- 2001-02-02 WO PCT/US2001/003385 patent/WO2001057027A1/en active IP Right Grant
- 2001-02-02 PT PT01905349T patent/PT1183253E/pt unknown
- 2001-02-02 MY MYPI20010481A patent/MY137637A/en unknown
- 2001-02-02 AU AU33239/01A patent/AU776051B2/en not_active Ceased
- 2001-02-02 JP JP2001557859A patent/JP2003522167A/ja active Pending
- 2001-02-02 CN CN01800306A patent/CN1362955A/zh active Pending
- 2001-02-02 RO ROA200101085A patent/RO121777B1/ro unknown
- 2001-02-02 KR KR1020017012600A patent/KR100784161B1/ko not_active IP Right Cessation
- 2001-02-02 BR BR0104749-3A patent/BR0104749A/pt not_active IP Right Cessation
- 2001-02-02 ES ES01905349T patent/ES2307588T3/es not_active Expired - Lifetime
- 2001-02-02 CZ CZ20013503A patent/CZ298484B6/cs not_active IP Right Cessation
- 2001-02-02 RU RU2001129507/04A patent/RU2265017C2/ru not_active IP Right Cessation
- 2001-02-02 MX MXPA01009901A patent/MXPA01009901A/es active IP Right Grant
- 2001-02-02 EP EP01905349A patent/EP1183253B8/en not_active Expired - Lifetime
- 2001-03-06 TW TW090102237A patent/TWI291873B/zh active
- 2001-04-11 SA SA1220045A patent/SA01220045B1/ar unknown
- 2001-10-01 NO NO20014759A patent/NO327982B1/no not_active IP Right Cessation
- 2001-10-01 ZA ZA200108060A patent/ZA200108060B/en unknown
- 2001-10-01 BG BG105967A patent/BG65279B1/bg unknown
-
2003
- 2003-01-07 HK HK03100173.6A patent/HK1047938A1/zh unknown
- 2003-06-25 US US10/606,027 patent/US7186849B2/en not_active Expired - Fee Related
-
2007
- 2007-01-09 US US11/621,321 patent/US20070249708A1/en not_active Abandoned
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