DK1183253T3 - C7-ester-substituerede taxaner som antitumormidler - Google Patents

C7-ester-substituerede taxaner som antitumormidler

Info

Publication number
DK1183253T3
DK1183253T3 DK01905349T DK01905349T DK1183253T3 DK 1183253 T3 DK1183253 T3 DK 1183253T3 DK 01905349 T DK01905349 T DK 01905349T DK 01905349 T DK01905349 T DK 01905349T DK 1183253 T3 DK1183253 T3 DK 1183253T3
Authority
DK
Denmark
Prior art keywords
ester
antitumor agents
substituted taxanes
taxanes
substituted
Prior art date
Application number
DK01905349T
Other languages
Danish (da)
English (en)
Inventor
Robert A Holton
Original Assignee
Univ Florida State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State Res Found filed Critical Univ Florida State Res Found
Application granted granted Critical
Publication of DK1183253T3 publication Critical patent/DK1183253T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK01905349T 2000-02-02 2001-02-02 C7-ester-substituerede taxaner som antitumormidler DK1183253T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17979400P 2000-02-02 2000-02-02
PCT/US2001/003385 WO2001057027A1 (en) 2000-02-02 2001-02-02 C7 ester substituted taxanes as antitumor agents

Publications (1)

Publication Number Publication Date
DK1183253T3 true DK1183253T3 (da) 2008-09-22

Family

ID=22658029

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01905349T DK1183253T3 (da) 2000-02-02 2001-02-02 C7-ester-substituerede taxaner som antitumormidler

Country Status (35)

Country Link
US (3) US6610860B2 (hu)
EP (1) EP1183253B8 (hu)
JP (1) JP2003522167A (hu)
KR (1) KR100784161B1 (hu)
CN (1) CN1362955A (hu)
AR (1) AR030188A1 (hu)
AT (1) ATE396188T1 (hu)
AU (1) AU776051B2 (hu)
BG (1) BG65279B1 (hu)
BR (1) BR0104749A (hu)
CA (1) CA2368993C (hu)
CO (1) CO5280224A1 (hu)
CZ (1) CZ298484B6 (hu)
DE (1) DE60134094D1 (hu)
DK (1) DK1183253T3 (hu)
ES (1) ES2307588T3 (hu)
GE (1) GEP20043322B (hu)
HK (1) HK1047938A1 (hu)
HU (1) HUP0200917A3 (hu)
IL (1) IL145641A0 (hu)
MX (1) MXPA01009901A (hu)
MY (1) MY137637A (hu)
NO (1) NO327982B1 (hu)
NZ (1) NZ514409A (hu)
PL (1) PL202668B1 (hu)
PT (1) PT1183253E (hu)
RO (1) RO121777B1 (hu)
RU (1) RU2265017C2 (hu)
SA (1) SA01220045B1 (hu)
SK (1) SK13712001A3 (hu)
TR (1) TR200102856T1 (hu)
TW (1) TWI291873B (hu)
UA (1) UA75573C2 (hu)
WO (1) WO2001057027A1 (hu)
ZA (1) ZA200108060B (hu)

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CZ20013498A3 (cs) * 2000-02-02 2002-04-17 Florida State University Research Foundation, Inc. Taxanové formulace mající zlepąenou rozpustnost
CA2354486A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C7 ester substituted taxanes
KR100819578B1 (ko) * 2001-08-01 2008-04-04 플로리다 스테이트 유니버시티 리서치 파운데이션, 인크 C7 에스테르 치환된 탁산
SG125889A1 (en) * 2001-08-01 2006-10-30 Univ Florida State Res Found C7 ester subsituted taxanes
US20030082229A1 (en) * 2001-11-01 2003-05-01 Board Of Regents, The University Of Texas Systems Parenteral chlorambucil for treatment of malignant and autoimmune disease and methods of use
US8012950B2 (en) * 2003-08-29 2011-09-06 Wisconsin Alumni Research Foundation Method to diagnose and treat degenerative joint disease
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US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
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US8664201B2 (en) 2008-07-31 2014-03-04 Ziopharm Oncology, Inc. Synthesis and formulations of salts of isophosphoramide mustard and analogs thereof
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US20230057461A1 (en) 2020-01-27 2023-02-23 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Rab13 and net1 antisense oligonucleotides to treat metastatic cancer
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Also Published As

Publication number Publication date
CO5280224A1 (es) 2003-05-30
SA01220045B1 (ar) 2008-06-07
ZA200108060B (en) 2003-12-01
NZ514409A (en) 2004-03-26
NO20014759D0 (no) 2001-10-01
HK1047938A1 (zh) 2003-03-14
WO2001057027A1 (en) 2001-08-09
PT1183253E (pt) 2008-08-04
US7186849B2 (en) 2007-03-06
PL202668B1 (pl) 2009-07-31
NO20014759L (no) 2001-11-29
CZ298484B6 (cs) 2007-10-17
NO327982B1 (no) 2009-11-02
CA2368993A1 (en) 2001-08-09
US20070249708A1 (en) 2007-10-25
GEP20043322B (en) 2003-12-10
CZ20013503A3 (cs) 2002-03-13
AR030188A1 (es) 2003-08-13
PL350026A1 (en) 2002-10-21
MY137637A (en) 2009-02-27
MXPA01009901A (es) 2003-07-28
BG105967A (en) 2002-08-30
RO121777B1 (ro) 2008-04-30
AU776051B2 (en) 2004-08-26
JP2003522167A (ja) 2003-07-22
TR200102856T1 (tr) 2002-06-21
KR20010111583A (ko) 2001-12-19
HUP0200917A3 (en) 2004-07-28
CN1362955A (zh) 2002-08-07
US20040014979A1 (en) 2004-01-22
BR0104749A (pt) 2001-12-26
IL145641A0 (en) 2002-06-30
US20020013346A1 (en) 2002-01-31
SK13712001A3 (sk) 2002-05-09
EP1183253A1 (en) 2002-03-06
EP1183253B1 (en) 2008-05-21
BG65279B1 (bg) 2007-11-30
TWI291873B (en) 2008-01-01
AU3323901A (en) 2001-08-14
HUP0200917A2 (en) 2002-08-28
ES2307588T3 (es) 2008-12-01
ATE396188T1 (de) 2008-06-15
HU0200917D0 (en) 2002-04-29
UA75573C2 (en) 2006-05-15
CA2368993C (en) 2009-10-20
EP1183253B8 (en) 2009-01-07
KR100784161B1 (ko) 2007-12-12
US6610860B2 (en) 2003-08-26
RU2265017C2 (ru) 2005-11-27
DE60134094D1 (de) 2008-07-03

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