DK1180517T3 - Fremgangsmåde til fremstilling af (all-rac)-alfa-tocopherol - Google Patents

Fremgangsmåde til fremstilling af (all-rac)-alfa-tocopherol

Info

Publication number
DK1180517T3
DK1180517T3 DK01119322T DK01119322T DK1180517T3 DK 1180517 T3 DK1180517 T3 DK 1180517T3 DK 01119322 T DK01119322 T DK 01119322T DK 01119322 T DK01119322 T DK 01119322T DK 1180517 T3 DK1180517 T3 DK 1180517T3
Authority
DK
Denmark
Prior art keywords
rac
tocopherol
alpha
acid
preparation
Prior art date
Application number
DK01119322T
Other languages
English (en)
Inventor
Werner Bonrath
Alois Haas
Eike Hoppmann
Horst Pauling
Original Assignee
Roche Vitamins Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Vitamins Ag filed Critical Roche Vitamins Ag
Application granted granted Critical
Publication of DK1180517T3 publication Critical patent/DK1180517T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK01119322T 2000-08-18 2001-08-10 Fremgangsmåde til fremstilling af (all-rac)-alfa-tocopherol DK1180517T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00117761 2000-08-18

Publications (1)

Publication Number Publication Date
DK1180517T3 true DK1180517T3 (da) 2003-11-17

Family

ID=8169565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01119322T DK1180517T3 (da) 2000-08-18 2001-08-10 Fremgangsmåde til fremstilling af (all-rac)-alfa-tocopherol

Country Status (11)

Country Link
US (1) US6482961B2 (da)
EP (1) EP1180517B1 (da)
JP (1) JP2002128775A (da)
KR (1) KR20020014769A (da)
CN (1) CN1182131C (da)
AT (1) ATE246181T1 (da)
BR (1) BR0103412A (da)
CA (1) CA2354997A1 (da)
DE (1) DE60100528T2 (da)
DK (1) DK1180517T3 (da)
ES (1) ES2204792T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE532764T1 (de) 2001-12-14 2011-11-15 Dsm Ip Assets Bv Herstellung von trimethylhydrochinondiacylaten
AU2003210291A1 (en) * 2002-02-25 2003-09-09 Dsm Ip Assets B.V. MANUFACTURE OF (ALL-RAC)-Alpha-TOCOPHEROL
AU2003270295A1 (en) * 2002-11-21 2004-06-15 Dsm Ip Assets B.V. MANUFACTURE OF Alpha-TOCOPHEROL
DE102004038800A1 (de) 2003-08-13 2005-03-31 Dsm Ip Assets B.V. Herstellung von Tocol, Tocolderivaten und Tocopherolen
JP4493393B2 (ja) * 2004-04-23 2010-06-30 東京応化工業株式会社 リソグラフィー用リンス液
US9958363B2 (en) * 2014-06-23 2018-05-01 Agilent Technologies, Inc. Fluorous affinity extraction for ionic liquid-based sample preparation
CN109529902B (zh) * 2018-11-30 2021-08-17 西安凯立新材料股份有限公司 一种高稳定的钯镍炭催化剂催化合成维生素e中间体的方法
CN111646968B (zh) * 2020-05-28 2022-04-22 万华化学集团股份有限公司 一种制备维生素e的方法
CN113083339B (zh) * 2021-04-15 2022-11-08 万华化学(四川)有限公司 一种用于制备维生素e的催化剂及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273840A (en) 1990-08-01 1993-12-28 Covalent Associates Incorporated Methide salts, formulations, electrolytes and batteries formed therefrom
JP3848380B2 (ja) 1993-12-14 2006-11-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 α−トコフェロール誘導体の製造法
US5554664A (en) 1995-03-06 1996-09-10 Minnesota Mining And Manufacturing Company Energy-activatable salts with fluorocarbon anions
US5908939A (en) * 1996-11-11 1999-06-01 Roche Vitamins Inc. Method of making D,L-A-tocopherol
ES2264230T3 (es) 1998-04-06 2006-12-16 Dsm Ip Assets B.V. Procedimiento par ala obtencion de d,1-alfa-tocoferol, en un disolvente de carbonato y en presencia de un catalizador de acido conteniendo azufre.
EP1000940A1 (en) * 1998-11-11 2000-05-17 F. Hoffmann-La Roche Ag Process for manufacturing d,l-alpha-tocopherol

Also Published As

Publication number Publication date
EP1180517A1 (en) 2002-02-20
JP2002128775A (ja) 2002-05-09
ATE246181T1 (de) 2003-08-15
EP1180517B1 (en) 2003-07-30
ES2204792T3 (es) 2004-05-01
US6482961B2 (en) 2002-11-19
KR20020014769A (ko) 2002-02-25
CA2354997A1 (en) 2002-02-18
US20020072619A1 (en) 2002-06-13
DE60100528D1 (de) 2003-09-04
CN1182131C (zh) 2004-12-29
DE60100528T2 (de) 2004-04-15
BR0103412A (pt) 2002-03-26
CN1339437A (zh) 2002-03-13

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