DE60100528D1 - Verfahren zur Herstellung von (alle-rac)-alfa-Tocopherol - Google Patents

Verfahren zur Herstellung von (alle-rac)-alfa-Tocopherol

Info

Publication number
DE60100528D1
DE60100528D1 DE60100528T DE60100528T DE60100528D1 DE 60100528 D1 DE60100528 D1 DE 60100528D1 DE 60100528 T DE60100528 T DE 60100528T DE 60100528 T DE60100528 T DE 60100528T DE 60100528 D1 DE60100528 D1 DE 60100528D1
Authority
DE
Germany
Prior art keywords
rac
tocopherol
acid
alle
alfa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60100528T
Other languages
English (en)
Other versions
DE60100528T2 (de
Inventor
Werner Bonrath
Alois Haas
Eike Hoppmann
Horst Pauling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
Roche Vitamins AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Vitamins AG filed Critical Roche Vitamins AG
Publication of DE60100528D1 publication Critical patent/DE60100528D1/de
Application granted granted Critical
Publication of DE60100528T2 publication Critical patent/DE60100528T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Catalysts (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60100528T 2000-08-18 2001-08-10 Verfahren zur Herstellung von (alle-rac)-alfa-Tocopherol Expired - Lifetime DE60100528T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00117761 2000-08-18
EP00117761 2000-08-18

Publications (2)

Publication Number Publication Date
DE60100528D1 true DE60100528D1 (de) 2003-09-04
DE60100528T2 DE60100528T2 (de) 2004-04-15

Family

ID=8169565

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60100528T Expired - Lifetime DE60100528T2 (de) 2000-08-18 2001-08-10 Verfahren zur Herstellung von (alle-rac)-alfa-Tocopherol

Country Status (11)

Country Link
US (1) US6482961B2 (de)
EP (1) EP1180517B1 (de)
JP (1) JP2002128775A (de)
KR (1) KR20020014769A (de)
CN (1) CN1182131C (de)
AT (1) ATE246181T1 (de)
BR (1) BR0103412A (de)
CA (1) CA2354997A1 (de)
DE (1) DE60100528T2 (de)
DK (1) DK1180517T3 (de)
ES (1) ES2204792T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4508642B2 (ja) * 2001-12-14 2010-07-21 ディーエスエム アイピー アセッツ ビー．ブイ． トリメチルヒドロキノンジアシレートの製造
AU2003210291A1 (en) * 2002-02-25 2003-09-09 Dsm Ip Assets B.V. MANUFACTURE OF (ALL-RAC)-Alpha-TOCOPHEROL
DE10393642B4 (de) * 2002-11-21 2017-03-30 Dsm Ip Assets B.V. Herstellung von α-Tocopherol
DE102004038800A1 (de) 2003-08-13 2005-03-31 Dsm Ip Assets B.V. Herstellung von Tocol, Tocolderivaten und Tocopherolen
JP4493393B2 (ja) * 2004-04-23 2010-06-30 東京応化工業株式会社 リソグラフィー用リンス液
US9958363B2 (en) * 2014-06-23 2018-05-01 Agilent Technologies, Inc. Fluorous affinity extraction for ionic liquid-based sample preparation
CN109529902B (zh) * 2018-11-30 2021-08-17 西安凯立新材料股份有限公司 一种高稳定的钯镍炭催化剂催化合成维生素e中间体的方法
CN111646968B (zh) * 2020-05-28 2022-04-22 万华化学集团股份有限公司 一种制备维生素e的方法
CN113083339B (zh) * 2021-04-15 2022-11-08 万华化学(四川)有限公司 一种用于制备维生素e的催化剂及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273840A (en) 1990-08-01 1993-12-28 Covalent Associates Incorporated Methide salts, formulations, electrolytes and batteries formed therefrom
JP3848380B2 (ja) 1993-12-14 2006-11-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 α−トコフェロール誘導体の製造法
US5554664A (en) 1995-03-06 1996-09-10 Minnesota Mining And Manufacturing Company Energy-activatable salts with fluorocarbon anions
US5908939A (en) * 1996-11-11 1999-06-01 Roche Vitamins Inc. Method of making D,L-A-tocopherol
DE69931421T2 (de) 1998-04-06 2006-11-09 Dsm Ip Assets B.V. Verfahren zur Herstellung von d,l-alpha-Tocopherol in einem Carbonat-Lösungsmittel und in Anwesenheit eines sauren schwefelhaltigen Katalysators
EP1000940A1 (de) * 1998-11-11 2000-05-17 F. Hoffmann-La Roche Ag Verfahren zur Herstellung von d,l-alpha-Tocopherol

Also Published As

Publication number Publication date
US20020072619A1 (en) 2002-06-13
KR20020014769A (ko) 2002-02-25
EP1180517B1 (de) 2003-07-30
CN1339437A (zh) 2002-03-13
EP1180517A1 (de) 2002-02-20
CA2354997A1 (en) 2002-02-18
JP2002128775A (ja) 2002-05-09
DK1180517T3 (da) 2003-11-17
CN1182131C (zh) 2004-12-29
BR0103412A (pt) 2002-03-26
US6482961B2 (en) 2002-11-19
DE60100528T2 (de) 2004-04-15
ATE246181T1 (de) 2003-08-15
ES2204792T3 (es) 2004-05-01

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: DSM IP ASSETS B.V., HEERLEN, NL

8364 No opposition during term of opposition