DK1102596T3 - Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf - Google Patents

Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf

Info

Publication number
DK1102596T3
DK1102596T3 DK99940809T DK99940809T DK1102596T3 DK 1102596 T3 DK1102596 T3 DK 1102596T3 DK 99940809 T DK99940809 T DK 99940809T DK 99940809 T DK99940809 T DK 99940809T DK 1102596 T3 DK1102596 T3 DK 1102596T3
Authority
DK
Denmark
Prior art keywords
peptide antagonists
methods
zonulin
zonulin peptide
opening
Prior art date
Application number
DK99940809T
Other languages
Danish (da)
English (en)
Inventor
Alessio Fasano
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland filed Critical Univ Maryland
Application granted granted Critical
Publication of DK1102596T3 publication Critical patent/DK1102596T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK99940809T 1998-08-03 1999-07-28 Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf DK1102596T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/127,815 US6458925B1 (en) 1998-08-03 1998-08-03 Peptide antagonists of zonulin and methods for use of the same

Publications (1)

Publication Number Publication Date
DK1102596T3 true DK1102596T3 (da) 2006-10-09

Family

ID=22432094

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99940809T DK1102596T3 (da) 1998-08-03 1999-07-28 Peptidantagonister af zonulin og fremgangsmåder til anvendelse heraf

Country Status (18)

Country Link
US (10) US6458925B1 (enExample)
EP (2) EP1698345B1 (enExample)
JP (1) JP4822585B2 (enExample)
KR (1) KR100610389B1 (enExample)
CN (2) CN100348266C (enExample)
AT (2) ATE329606T1 (enExample)
AU (1) AU745507B2 (enExample)
CA (1) CA2338005C (enExample)
DE (2) DE69942753D1 (enExample)
DK (1) DK1102596T3 (enExample)
ES (1) ES2267282T3 (enExample)
HU (1) HU228079B1 (enExample)
IL (2) IL141082A0 (enExample)
NO (1) NO326552B1 (enExample)
NZ (1) NZ509579A (enExample)
RU (1) RU2214267C2 (enExample)
WO (1) WO2000007609A1 (enExample)
ZA (1) ZA200100829B (enExample)

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US6458925B1 (en) * 1998-08-03 2002-10-01 University Of Maryland, Baltimore Peptide antagonists of zonulin and methods for use of the same
CA2409771C (en) * 2000-05-19 2008-12-02 University Of Maryland, Baltimore Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes
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EP1485074A2 (fr) * 2002-03-15 2004-12-15 Rytek Compositions pour le traitement de pathologies fonctionnelles digestives
KR20080056318A (ko) * 2003-07-15 2008-06-20 유니버시티 오브 메릴랜드, 볼티모어 Ｚｏｔ 및 조눌린에 대한 수용체의 작용제 폴리펩티드
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Also Published As

Publication number Publication date
CN1217697C (zh) 2005-09-07
US7531504B2 (en) 2009-05-12
DE69942753D1 (de) 2010-10-21
EP1102596A4 (en) 2002-08-14
US20050209161A1 (en) 2005-09-22
US20110183923A1 (en) 2011-07-28
US6670448B2 (en) 2003-12-30
US7189696B2 (en) 2007-03-13
IL141082A (en) 2012-09-24
HK1082210A1 (zh) 2006-06-02
EP1698345A2 (en) 2006-09-06
ES2267282T3 (es) 2007-03-01
HUP0103321A3 (en) 2006-01-30
AU5459099A (en) 2000-02-28
CA2338005C (en) 2012-05-29
CN100348266C (zh) 2007-11-14
EP1102596B1 (en) 2006-06-14
JP4822585B2 (ja) 2011-11-24
IL141082A0 (en) 2002-02-10
RU2214267C2 (ru) 2003-10-20
WO2000007609A1 (en) 2000-02-17
KR100610389B1 (ko) 2006-08-09
KR20010072245A (ko) 2001-07-31
AU745507B2 (en) 2002-03-21
US20040082512A1 (en) 2004-04-29
EP1102596A1 (en) 2001-05-30
HUP0103321A2 (hu) 2001-12-28
US6936689B2 (en) 2005-08-30
US20140128328A1 (en) 2014-05-08
ATE329606T1 (de) 2006-07-15
CN1679915A (zh) 2005-10-12
US20060276399A1 (en) 2006-12-07
US20130190247A1 (en) 2013-07-25
US20020115825A1 (en) 2002-08-22
NO20010567L (no) 2001-04-02
NO20010567D0 (no) 2001-02-02
EP1698345A3 (en) 2006-09-13
US20090082279A1 (en) 2009-03-26
JP2002524393A (ja) 2002-08-06
US6458925B1 (en) 2002-10-01
ATE480252T1 (de) 2010-09-15
HU228079B1 (en) 2012-10-29
EP1698345B1 (en) 2010-09-08
CN1313772A (zh) 2001-09-19
NO326552B1 (no) 2009-01-05
DE69931929T2 (de) 2007-02-08
US7582603B2 (en) 2009-09-01
US20080051349A1 (en) 2008-02-28
CA2338005A1 (en) 2000-02-17
ZA200100829B (en) 2002-06-26
NZ509579A (en) 2003-07-25
DE69931929D1 (de) 2006-07-27

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