JP4822585B2 - ゾヌリンのペプチドアンタゴニストおよびその使用方法 - Google Patents
ゾヌリンのペプチドアンタゴニストおよびその使用方法 Download PDFInfo
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- JP4822585B2 JP4822585B2 JP2000563294A JP2000563294A JP4822585B2 JP 4822585 B2 JP4822585 B2 JP 4822585B2 JP 2000563294 A JP2000563294 A JP 2000563294A JP 2000563294 A JP2000563294 A JP 2000563294A JP 4822585 B2 JP4822585 B2 JP 4822585B2
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- zonulin
- zot
- seq
- purified
- human
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4716—Muscle proteins, e.g. myosin, actin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
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- Immunology (AREA)
- Pulmonology (AREA)
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- Pain & Pain Management (AREA)
- Oncology (AREA)
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| PCT/US1999/016683 WO2000007609A1 (en) | 1998-08-03 | 1999-07-28 | Peptide antagonists of zonulin and methods for use of the same |
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| US6458925B1 (en) * | 1998-08-03 | 2002-10-01 | University Of Maryland, Baltimore | Peptide antagonists of zonulin and methods for use of the same |
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| JP2005526772A (ja) * | 2002-03-15 | 2005-09-08 | リテック | 消化機能病理を処置するための組成物 |
| FR2844201A1 (fr) * | 2002-09-06 | 2004-03-12 | Rytek | Compositions pour le traitement de pathologies fonctionnelles digestives |
| JP2007534621A (ja) * | 2003-07-15 | 2007-11-29 | ユニバーシティ オブ メリーランド， ボルチモア | Ｚｏｔおよびゾニューリンに対するレセプターのアゴニストペプチド |
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| JP2002524531A (ja) * | 1998-09-14 | 2002-08-06 | ユニバーシティ・オブ・メリーランド， ボルティモア | 抗原特異的様式でリンパ球増殖を阻害するための、Ｚｏｔまたはゾヌリンを使用する方法 |
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| US5945510A (en) * | 1997-05-21 | 1999-08-31 | University Of Maryland, Baltimore | Substantially pure zonulin, a physiological modulator of mammalian tight junctions |
| US6506577B1 (en) * | 1998-03-19 | 2003-01-14 | The Regents Of The University Of California | Synthesis and crosslinking of catechol containing copolypeptides |
| US6458925B1 (en) | 1998-08-03 | 2002-10-01 | University Of Maryland, Baltimore | Peptide antagonists of zonulin and methods for use of the same |
| DE60139466D1 (de) * | 2000-05-19 | 2009-09-17 | Univ Maryland | Behandlung von diabetes |
| US8034776B2 (en) * | 2006-10-26 | 2011-10-11 | Alba Therapeutics Corporation | Materials and methods for the treatment of celiac disease |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2002524531A (ja) * | 1998-09-14 | 2002-08-06 | ユニバーシティ・オブ・メリーランド， ボルティモア | 抗原特異的様式でリンパ球増殖を阻害するための、Ｚｏｔまたはゾヌリンを使用する方法 |
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Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| EXPY | Cancellation because of completion of term |