DK1096954T3 - Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A - Google Patents

Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A

Info

Publication number
DK1096954T3
DK1096954T3 DK99935566T DK99935566T DK1096954T3 DK 1096954 T3 DK1096954 T3 DK 1096954T3 DK 99935566 T DK99935566 T DK 99935566T DK 99935566 T DK99935566 T DK 99935566T DK 1096954 T3 DK1096954 T3 DK 1096954T3
Authority
DK
Denmark
Prior art keywords
adjuvant
vaccine compositions
monophosphoryl lipid
compositions containing
containing monophosphoryl
Prior art date
Application number
DK99935566T
Other languages
Danish (da)
English (en)
Inventor
Vincent James Laposta
John Hayward Eldridge
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1096954T3 publication Critical patent/DK1096954T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK99935566T 1998-07-14 1999-07-13 Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A DK1096954T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11539298A 1998-07-14 1998-07-14
EP99935566A EP1096954B1 (fr) 1998-07-14 1999-07-13 Compositions d'adjuvants et de vaccins contenant un lipide monophosphoryle a

Publications (1)

Publication Number Publication Date
DK1096954T3 true DK1096954T3 (da) 2005-01-31

Family

ID=22361090

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99935566T DK1096954T3 (da) 1998-07-14 1999-07-13 Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A

Country Status (14)

Country Link
EP (1) EP1096954B1 (fr)
JP (1) JP2002520373A (fr)
KR (1) KR100586804B1 (fr)
CN (1) CN1247262C (fr)
AT (1) ATE278420T1 (fr)
AU (1) AU763770B2 (fr)
BR (1) BR9912067A (fr)
CA (1) CA2333578C (fr)
DE (1) DE69920915T2 (fr)
DK (1) DK1096954T3 (fr)
ES (1) ES2229745T3 (fr)
IL (1) IL140890A0 (fr)
PT (1) PT1096954E (fr)
WO (1) WO2000003744A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ526879A (en) 1998-12-22 2004-12-24 Microscience Ltd Genes and proteins, and their use
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
MXPA02011486A (es) * 2000-05-19 2004-01-26 Corixa Corp Tratamiento profilactico y terapeutico de enfermedades infecciosas, autoinmunes y alergicas con compuestos a base de mono y disacarido.
FR2814956B1 (fr) * 2000-10-06 2003-01-24 Seppic Sa Nouvelle composition vaccinale, procede pour sa preparation, utilisation comme composition injectale en medecine humaine ou veterinaire et nouveau procede de conservation
PL1909830T3 (pl) * 2005-08-02 2012-02-29 Novartis Vaccines And Diagnostics S R L Ograniczenie oddziaływania pomiędzy olejem w adiuwancie a środkiem powierzchniowo czynnym w antygenie
WO2013006569A2 (fr) * 2011-07-01 2013-01-10 The Regents Of The University Of California Vaccin contre le virus de l'herpès et procédés d'utilisation
US9241988B2 (en) 2012-04-12 2016-01-26 Avanti Polar Lipids, Inc. Disaccharide synthetic lipid compounds and uses thereof
CN105517555A (zh) * 2013-09-05 2016-04-20 免疫设计股份有限公司 针对药物成瘾的疫苗组合物
CN116199727A (zh) * 2021-12-01 2023-06-02 上海安奕康生物科技有限公司 一种mpl三乙胺盐、其制备工艺及应用
WO2023212702A2 (fr) * 2022-04-28 2023-11-02 Kansas State University Research Foundation Enfermement de colloïdes peptidiques amphipathiques

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2672496B3 (fr) * 1990-07-18 1993-05-28 Vacsyn France Sa Compositions a base de substances hydrophobes, solubilisables dans un solvant aqueux, leur procede d'obtention, et leurs utilisations notamment dans le domaine pharmaceutique.
EP1175912A1 (fr) * 1993-03-23 2002-01-30 SmithKline Beecham Biologics SA Compositions vaccinales renfermant le lipide à monophosphorylique 3-O désacétylé
US5565204A (en) * 1994-08-24 1996-10-15 American Cyanamid Company Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US5762943A (en) * 1996-05-14 1998-06-09 Ribi Immunochem Research, Inc. Methods of treating type I hypersensitivity using monophosphoryl lipid A
GB9612137D0 (en) * 1996-06-10 1996-08-14 Quaker Oats Co Treatment of dried fruit
ATE298578T1 (de) * 1996-07-03 2005-07-15 Eisai Co Ltd Lipid a-analoge enthaltende injektionen und verfahren zu deren herstellung

Also Published As

Publication number Publication date
PT1096954E (pt) 2004-12-31
BR9912067A (pt) 2001-04-10
KR100586804B1 (ko) 2006-06-07
DE69920915D1 (de) 2004-11-11
ATE278420T1 (de) 2004-10-15
WO2000003744A3 (fr) 2000-04-27
IL140890A0 (en) 2002-02-10
CN1247262C (zh) 2006-03-29
CA2333578C (fr) 2010-11-16
JP2002520373A (ja) 2002-07-09
KR20010071637A (ko) 2001-07-28
CN1307483A (zh) 2001-08-08
AU5101899A (en) 2000-02-07
EP1096954A2 (fr) 2001-05-09
AU763770B2 (en) 2003-07-31
EP1096954B1 (fr) 2004-10-06
WO2000003744A2 (fr) 2000-01-27
DE69920915T2 (de) 2006-02-16
ES2229745T3 (es) 2005-04-16
CA2333578A1 (fr) 2000-01-27

Similar Documents

Publication Publication Date Title
WO2003039330A3 (fr) Appareils permettant de corriger et de traiter des deformations de la colonne vertebrale et techniques correspondants
ATE278420T1 (de) Monophosphoryllipid a enthaltende adjuvans- und impfstoffzusammensetzungen
NZ508110A (en) Attenuated mutants of salmonella which constitutively express the Vi antigen
WO1999040936A3 (fr) Vaccins pneumococciques ou meningococciques formules avec l'interleukine-12
NZ513202A (en) Antigen composition comprising Bordetella bronchiseptica, formalin and glutaraldehyde
EP1100522A4 (fr) Administration de substances actives par la voie pulmonaire
ATE238415T1 (de) Feste phytase-zusammensetzungen
NO20002741D0 (no) Vaksine-blandinger omfattende kitosan, for mukosal administrasjon
DE69524742D1 (de) Interleukin-11 präparat
JO2386B1 (en) Dispersing compounds containing lipase inhibitors
BR0011030A (pt) Composições de cicloporina substancialmente livre de óleo
BG103914A (en) Maintained separation of delayed gels
DE69634024D1 (de) Adjuvans für vitale Impfstoffe
CA2177667A1 (fr) Compositions de vaccin pour mammiferes comprenant un adjuvant constitue de squalene ou de squalane, lecithine et un ester polyoxyethylene sorbitan
DK1053017T3 (da) Vacciner omfattende interleukin-12 og herpes simplex virusantigen
MXPA01003501A (es) Metodo para moderar el estres o tension de las plantas.
WO2000033887A3 (fr) Procedes et formulations permettant de reduire des anticorps circulants
AU2001258373A1 (en) Method for identifying helicobacter antigens
AU6849198A (en) Neurotrypsin
CA2442698A1 (fr) Liposome thermolabile a temperature de liberation regulee
BG105372A (en) Immunogenic liposome compositions
AR016514A1 (es) Composicion para mejorar el malestar estomacal, metodo para preparar dicha composicion y metodo para utilizarla
MXPA05009447A (es) Vacunas bovinas con adyuvante.
WO2003006645A3 (fr) Methode et composition permettant d'inhiber l'activite de l'heparanase
DE69905915D1 (de) Triaryl phosphatesterzusammensetzung