DK1038522T3 - Antikonvulsive enantiomere aminosyrederivater - Google Patents

Antikonvulsive enantiomere aminosyrederivater

Info

Publication number
DK1038522T3
DK1038522T3 DK00109377T DK00109377T DK1038522T3 DK 1038522 T3 DK1038522 T3 DK 1038522T3 DK 00109377 T DK00109377 T DK 00109377T DK 00109377 T DK00109377 T DK 00109377T DK 1038522 T3 DK1038522 T3 DK 1038522T3
Authority
DK
Denmark
Prior art keywords
anticonvulsant
amino acid
acid derivatives
enantiomeric amino
animal
Prior art date
Application number
DK00109377T
Other languages
Danish (da)
English (en)
Inventor
Harold Kohn
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21760388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1038522(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Application granted granted Critical
Publication of DK1038522T3 publication Critical patent/DK1038522T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00109377T 1996-03-15 1997-03-17 Antikonvulsive enantiomere aminosyrederivater DK1038522T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1352296P 1996-03-15 1996-03-15

Publications (1)

Publication Number Publication Date
DK1038522T3 true DK1038522T3 (da) 2004-10-11

Family

ID=21760388

Family Applications (2)

Application Number Title Priority Date Filing Date
DK00109377T DK1038522T3 (da) 1996-03-15 1997-03-17 Antikonvulsive enantiomere aminosyrederivater
DK97916897T DK0888289T3 (da) 1996-03-15 1997-03-17 Antikonvulsive, enantiomore aminosyrederivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK97916897T DK0888289T3 (da) 1996-03-15 1997-03-17 Antikonvulsive, enantiomore aminosyrederivater

Country Status (12)

Country Link
EP (2) EP1038522B1 (fr)
JP (1) JP3145414B2 (fr)
AT (2) ATE268169T1 (fr)
AU (1) AU718577B2 (fr)
CA (1) CA2248317C (fr)
DE (3) DE69705210T2 (fr)
DK (2) DK1038522T3 (fr)
ES (2) ES2218024T3 (fr)
FR (1) FR09C0006I2 (fr)
NL (1) NL300376I1 (fr)
PT (2) PT1038522E (fr)
WO (1) WO1997033861A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048899A (en) * 1997-03-17 2000-04-11 Research Corporation Tech., Inc. Anticonvulsant enantiomeric amino acid derivatives
EP1642889A1 (fr) * 2004-10-02 2006-04-05 Schwarz Pharma Ag Route de synthèse améliorée pour lacosamide
EP1873527A1 (fr) 2006-06-30 2008-01-02 Schwarz Pharma Ag Procédé d'identification des modulateurs CRMP
US8093426B2 (en) * 2007-12-04 2012-01-10 Ranbaxy Laboratories Limited Intermediate compounds and their use in preparation of lacosamide
DE102008059155A1 (de) 2008-11-27 2010-06-02 Ratiopharm Gmbh Trockenverarbeitung und neue Formen von Lacosamid
EP2462107A1 (fr) 2009-08-06 2012-06-13 Medichem, S.A. Formes solides d'un dérivé de n-(phénylméthyl)propanamide et leurs procédés de préparation
WO2011039781A1 (fr) * 2009-09-25 2011-04-07 Cadila Healthcare Limited Procédés d'élaboration de lacosamide et intermédiaires correspondants
IT1398044B1 (it) * 2010-01-29 2013-02-07 Archimica Srl Processo per la preparazione della lacosamide
KR20120128667A (ko) 2010-02-08 2012-11-27 낫코 파마 리미티드 라코사미드의 제조방법
US8907132B2 (en) 2010-02-09 2014-12-09 Msn Laboratories Private Limited Process for preparing (R)-2-acetamido-N-benzyl-3-methoxy-propionamide
EP2399901A1 (fr) 2010-06-23 2011-12-28 Archimica GmbH Intermédiaire pour produire de la lacosamide et son procédé de préparation et conversion en lacosamide
WO2012041986A1 (fr) 2010-10-01 2012-04-05 Ucb Pharma Gmbh Procédé de synthèse de dérivés d'acides aminés
WO2012051551A1 (fr) * 2010-10-15 2012-04-19 Nektar Therapeutics Aryl-2-oligomère-3-alcoxypropionamides éventuellement substitués en n
HUE031138T2 (en) 2010-10-19 2017-06-28 Euticals Gmbh A method of producing lacosamide
EP2468261A1 (fr) 2010-12-02 2012-06-27 UCB Pharma GmbH Formulation de lacosamide
EP2645997B1 (fr) 2010-12-02 2022-08-10 UCB Pharma GmbH Formulation de lacosamide en prise quotidienne unique
CN104771356A (zh) * 2014-01-09 2015-07-15 山东方明药业集团股份有限公司 一种拉科酰胺注射液及其制备方法
US11278634B1 (en) 2021-02-12 2022-03-22 Extrovis Ag Stable parenteral composition of lacosamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
ATE62222T1 (de) * 1985-02-15 1991-04-15 Res Corp Technologies Inc Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.

Also Published As

Publication number Publication date
EP1038522A3 (fr) 2003-01-15
ATE202079T1 (de) 2001-06-15
DE69705210D1 (de) 2001-07-19
EP1038522B1 (fr) 2004-06-02
DK0888289T3 (da) 2001-09-03
NL300376I1 (nl) 2009-05-06
ES2218024T3 (es) 2004-11-16
EP1038522A2 (fr) 2000-09-27
DE69729392D1 (de) 2004-07-08
EP0888289A1 (fr) 1999-01-07
FR09C0006I2 (fr) 2009-12-18
JP2000505476A (ja) 2000-05-09
FR09C0006I1 (fr) 2009-04-17
ATE268169T1 (de) 2004-06-15
WO1997033861A1 (fr) 1997-09-18
CA2248317A1 (fr) 1997-09-18
ES2157567T3 (es) 2001-08-16
CA2248317C (fr) 2003-12-02
PT1038522E (pt) 2004-10-29
DE122009000010I2 (de) 2010-10-21
AU718577B2 (en) 2000-04-13
EP0888289B1 (fr) 2001-06-13
JP3145414B2 (ja) 2001-03-12
DE69705210T2 (de) 2001-09-20
PT888289E (pt) 2001-09-28
DE69729392T2 (de) 2005-06-02
DE122009000010I1 (de) 2009-05-20
AU2539497A (en) 1997-10-01

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