DK1032605T3 - Polyanhydrider med terapeutisk anvendelige nedbrydningsprodukter - Google Patents
Polyanhydrider med terapeutisk anvendelige nedbrydningsprodukterInfo
- Publication number
- DK1032605T3 DK1032605T3 DK98946004T DK98946004T DK1032605T3 DK 1032605 T3 DK1032605 T3 DK 1032605T3 DK 98946004 T DK98946004 T DK 98946004T DK 98946004 T DK98946004 T DK 98946004T DK 1032605 T3 DK1032605 T3 DK 1032605T3
- Authority
- DK
- Denmark
- Prior art keywords
- ortho
- aromatic
- substituted
- polyanhydrides
- dicarboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
- C08G67/04—Polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicinal Preparation (AREA)
- Polyethers (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5832897P | 1997-09-10 | 1997-09-10 | |
PCT/US1998/018816 WO1999012990A1 (en) | 1997-09-10 | 1998-09-10 | Polyanhydrides with therapeutically useful degradation products |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1032605T3 true DK1032605T3 (da) | 2008-03-17 |
Family
ID=22016145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98946004T DK1032605T3 (da) | 1997-09-10 | 1998-09-10 | Polyanhydrider med terapeutisk anvendelige nedbrydningsprodukter |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1032605B1 (ko) |
JP (2) | JP4130305B2 (ko) |
KR (1) | KR20010023852A (ko) |
CN (1) | CN1158325C (ko) |
AT (1) | ATE378364T1 (ko) |
AU (1) | AU750424C (ko) |
CA (1) | CA2302508C (ko) |
CY (1) | CY1107857T1 (ko) |
DE (1) | DE69838731T2 (ko) |
DK (1) | DK1032605T3 (ko) |
ES (1) | ES2296344T3 (ko) |
PT (1) | PT1032605E (ko) |
WO (1) | WO1999012990A1 (ko) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7985415B2 (en) | 1997-09-10 | 2011-07-26 | Rutgers, The State University Of New Jersey | Medical devices employing novel polymers |
US6486214B1 (en) * | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
US6468519B1 (en) * | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
US7122615B1 (en) | 1998-09-10 | 2006-10-17 | Rutgers, The State University Of New Jersey | Polyanhydrides with therapeutically useful degradation products |
US6685928B2 (en) * | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
DE60043075D1 (de) * | 1999-12-07 | 2009-11-12 | Univ Rutgers | Therapeutische zusammensetzungen und verfahren zur behandlung von periodontitis mit entzündunshemmenden mitteln |
US20040038948A1 (en) | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
US8109994B2 (en) | 2003-01-10 | 2012-02-07 | Abbott Cardiovascular Systems, Inc. | Biodegradable drug delivery material for stent |
CA2417389C (en) | 2000-07-27 | 2012-05-29 | Rutgers, The State University | Therapeutic polyesters and polyamides |
WO2002009769A2 (en) | 2000-07-27 | 2002-02-07 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
IL140017A (en) * | 2000-11-30 | 2009-09-22 | Abraham J Domb | Polyhedra |
DE60231555D1 (de) | 2001-11-23 | 2009-04-23 | Theodore James Anastasiou | Verbesserte synthese von polyanhydriden |
AU2003225882A1 (en) * | 2002-03-20 | 2003-10-08 | Advanced Cardiovascular Systems, Inc. | Biodegradable hydrophobic polymer for stents |
CA2503841A1 (en) * | 2002-10-28 | 2004-05-13 | Polymerix Corporation | Therapeutic compositions |
JP4987232B2 (ja) * | 2002-11-18 | 2012-07-25 | ラットガーズ,ザ・ステート・ユニバーシティ・オブ・ニュージャージー | 新規のポリマーを用いた医療用デバイス |
WO2005110485A1 (en) * | 2004-05-14 | 2005-11-24 | Interface Biologics Inc. | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
CA2467321A1 (en) | 2004-05-14 | 2005-11-14 | Paul J. Santerre | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
US8143368B2 (en) | 2004-12-23 | 2012-03-27 | Massachusetts Institute Of Technology | Disposable medical supplies from hydrolytically biodegradable plastics |
WO2006127667A1 (en) | 2005-05-23 | 2006-11-30 | Rutgers, The State University Of New Jersey | Fast degrading polymers |
EP1951260A4 (en) | 2005-10-21 | 2009-11-11 | Bezwada Biomedical Llc | FUNCTIONALIZED PHENOLIC COMPOUNDS AND POURABLE ARTICLES THEREOF |
US8007526B2 (en) | 2005-12-01 | 2011-08-30 | Bezwada Biomedical, Llc | Difunctionalized aromatic compounds and polymers therefrom |
AU2007256626A1 (en) * | 2006-06-06 | 2007-12-13 | Rutgers, The State University Of New Jersey | Iodinated polymers |
EP2102144A4 (en) | 2006-09-13 | 2011-03-23 | Univ Rutgers | ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS |
CN101240065B (zh) * | 2007-02-07 | 2010-05-19 | 天津大学 | 癸二酸酐与十八烷二元酸酐共聚物及其制备方法和应用 |
EP2146701B1 (en) | 2007-04-12 | 2013-10-16 | Rutgers, The State University of New Jersey | Biodegradable polyanhydrides with natural bioactive molecules |
US8217134B2 (en) | 2007-08-30 | 2012-07-10 | Bezwada Biomedical, Llc | Controlled release of biologically active compounds |
US8048980B2 (en) | 2007-09-17 | 2011-11-01 | Bezwada Biomedical, Llc | Hydrolysable linkers and cross-linkers for absorbable polymers |
CN101357244B (zh) * | 2008-09-18 | 2011-06-01 | 复旦大学附属肿瘤医院 | 纳米粒子增强的光固化聚酸酐载药聚合物支架的制备方法 |
EP2569015A1 (en) | 2010-05-14 | 2013-03-20 | Iberhospitex S.A. | Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers |
EP2694079B1 (en) * | 2011-04-06 | 2018-01-17 | Rutgers, The State University of New Jersey | Polymers and methods for the treatment of pain |
AU2013232300B2 (en) * | 2012-03-16 | 2015-12-17 | The Johns Hopkins University | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents |
JP5883539B2 (ja) * | 2012-03-16 | 2016-03-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | Hif−1阻害剤の送達のための放出制御製剤 |
US9144579B2 (en) | 2012-08-17 | 2015-09-29 | Rutgers, The State University Of New Jersey | Polyesters and methods of use thereof |
US20140120057A1 (en) | 2012-10-25 | 2014-05-01 | Rutgers, The State University Of New Jersey | Polymers and methods thereof for wound healing |
CN103910875B (zh) * | 2012-12-31 | 2017-06-13 | 张雅珍 | 蒽环类抗生素偶联非线性多嵌段共聚物及其制备方法和应用 |
US9387250B2 (en) | 2013-03-15 | 2016-07-12 | Rutgers, The State University Of New Jersey | Therapeutic compositions for bone repair |
US9862672B2 (en) | 2013-05-29 | 2018-01-09 | Rutgers, The State University Of New Jersey | Antioxidant-based poly(anhydride-esters) |
US10023521B2 (en) | 2014-06-13 | 2018-07-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
AU2015365566B2 (en) | 2014-12-18 | 2020-02-27 | Dexcel Pharma Technologies Ltd. | Alternating and semi-alternating poly(ester-anhydride) copolymers |
WO2016164898A1 (en) | 2015-04-10 | 2016-10-13 | Rutgers, The State University Of New Jersey | Kojic acid polymers |
EP3600438A4 (en) | 2017-03-29 | 2020-10-28 | Dexcel Pharma Technologies Ltd. | COMPOSITIONS CONTAINING BIODEGRADABLE COPOLYMERS |
US20210113457A1 (en) | 2018-02-02 | 2021-04-22 | Ripple Therapeutics Corporation | Glass formulations and uses thereof |
JP2022539168A (ja) * | 2019-07-05 | 2022-09-07 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 好中球損傷用ポリマー粒子 |
MX2022013665A (es) | 2020-05-01 | 2022-11-30 | Ripple Therapeutics Corp | Composiciones y metodos heterodimeros para el tratamiento de trastornos oculares. |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2607799A (en) * | 1949-09-22 | 1952-08-19 | Monsanto Chemicals | Process for the preparation of glycol esters of benzyl acid phthalate |
JPS51134729A (en) * | 1975-05-20 | 1976-11-22 | Asahi Chem Ind Co Ltd | Powdered coating composition |
JPS5382743A (en) * | 1976-12-27 | 1978-07-21 | Okura Ind Co Ltd | Preparation of glycol trimellitic acid anhydrides |
JPS567716A (en) * | 1979-07-03 | 1981-01-27 | Chugai Pharmaceut Co Ltd | Preventive and remedy for cerebral angiospasm |
US4757128A (en) * | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
US4891225A (en) * | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
US4886870A (en) * | 1984-05-21 | 1989-12-12 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
JPS6119649A (ja) * | 1984-07-06 | 1986-01-28 | Adeka Argus Chem Co Ltd | ポリ塩化ビニル系樹脂組成物 |
CH671402A5 (ko) * | 1985-10-02 | 1989-08-31 | Sandoz Ag | |
DE246341T1 (de) * | 1986-05-20 | 1989-03-30 | Massachusetts Institute Of Technology, Cambridge, Mass., Us | Bioerodierbare erzeugnisse zur verwendung als implantate oder prothese mit einem voraussehbaren resorbierungsgrad. |
US4997904A (en) * | 1989-08-25 | 1991-03-05 | Nova Pharmaceutical Corporation | Aromatic polyanhydride compositions |
DD288387A5 (de) * | 1989-10-16 | 1991-03-28 | Friedrich-Schiller-Universitaet Jena,De | Verfahren zur herstellung von poly(esteranhydriden) |
DD288311A5 (de) * | 1989-10-16 | 1991-03-28 | Friedrich-Schiller-Universitaet Jena,De | Verfahren zur gesteuerten freisetzung von biologisch aktiven verbindungen |
WO1991009831A1 (en) * | 1989-12-26 | 1991-07-11 | Nova Pharmaceutical Corporation | Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use |
US5175235A (en) * | 1990-06-04 | 1992-12-29 | Nova Pharmaceutical Corporation | Branched polyanhydrides |
US5264540A (en) * | 1992-07-20 | 1993-11-23 | Ethicon, Inc. | Aromatic polyanhydrides |
JPH06172426A (ja) * | 1992-12-08 | 1994-06-21 | Shin Etsu Chem Co Ltd | 側鎖にアセチルサリチル酸基を有する重合体 |
US5364725A (en) * | 1993-03-15 | 1994-11-15 | Eastman Kodak Company | Toner and developer containing acyloxy-t-alkylated benzoic acids as charge-control agent |
JP3255197B2 (ja) * | 1993-05-26 | 2002-02-12 | 株式会社リコー | 感熱記録材料 |
JP3091366B2 (ja) * | 1993-06-25 | 2000-09-25 | 信越化学工業株式会社 | アセチルサリチル酸ビニル−ビニルアルコール系共重合体 |
JP3122977B2 (ja) * | 1993-12-01 | 2001-01-09 | 富士写真フイルム株式会社 | 感熱記録材料 |
US5637113A (en) * | 1994-12-13 | 1997-06-10 | Advanced Cardiovascular Systems, Inc. | Polymer film for wrapping a stent structure |
US6060212A (en) * | 1998-06-11 | 2000-05-09 | Clariant Finance (Bvi) Limited | 193 nm positive-working photoresist composition |
DE60043075D1 (de) * | 1999-12-07 | 2009-11-12 | Univ Rutgers | Therapeutische zusammensetzungen und verfahren zur behandlung von periodontitis mit entzündunshemmenden mitteln |
US6685928B2 (en) * | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
NZ528994A (en) * | 2001-04-26 | 2006-02-24 | Control Delivery Sys Inc | Sustained release drug delivery system containing codrugs |
DE60231555D1 (de) * | 2001-11-23 | 2009-04-23 | Theodore James Anastasiou | Verbesserte synthese von polyanhydriden |
-
1998
- 1998-09-10 CN CNB988089629A patent/CN1158325C/zh not_active Expired - Fee Related
- 1998-09-10 WO PCT/US1998/018816 patent/WO1999012990A1/en active IP Right Grant
- 1998-09-10 AU AU93117/98A patent/AU750424C/en not_active Ceased
- 1998-09-10 ES ES98946004T patent/ES2296344T3/es not_active Expired - Lifetime
- 1998-09-10 CA CA2302508A patent/CA2302508C/en not_active Expired - Fee Related
- 1998-09-10 JP JP2000510791A patent/JP4130305B2/ja not_active Expired - Fee Related
- 1998-09-10 AT AT98946004T patent/ATE378364T1/de active
- 1998-09-10 DE DE69838731T patent/DE69838731T2/de not_active Expired - Lifetime
- 1998-09-10 DK DK98946004T patent/DK1032605T3/da active
- 1998-09-10 EP EP98946004A patent/EP1032605B1/en not_active Expired - Lifetime
- 1998-09-10 KR KR1020007002529A patent/KR20010023852A/ko not_active Application Discontinuation
- 1998-09-10 PT PT98946004T patent/PT1032605E/pt unknown
-
2007
- 2007-11-29 JP JP2007308503A patent/JP2008150367A/ja active Pending
-
2008
- 2008-01-14 CY CY20081100048T patent/CY1107857T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2296344T3 (es) | 2008-04-16 |
WO1999012990A1 (en) | 1999-03-18 |
AU750424B2 (en) | 2002-07-18 |
AU750424C (en) | 2003-05-15 |
EP1032605A4 (en) | 2002-03-13 |
KR20010023852A (ko) | 2001-03-26 |
PT1032605E (pt) | 2007-12-12 |
CA2302508C (en) | 2011-03-15 |
ATE378364T1 (de) | 2007-11-15 |
EP1032605B1 (en) | 2007-11-14 |
EP1032605A1 (en) | 2000-09-06 |
CY1107857T1 (el) | 2013-06-19 |
DE69838731T2 (de) | 2008-04-10 |
JP2001515934A (ja) | 2001-09-25 |
JP4130305B2 (ja) | 2008-08-06 |
JP2008150367A (ja) | 2008-07-03 |
AU9311798A (en) | 1999-03-29 |
CA2302508A1 (en) | 1999-03-18 |
DE69838731D1 (de) | 2007-12-27 |
CN1269811A (zh) | 2000-10-11 |
CN1158325C (zh) | 2004-07-21 |
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