DK1025114T3 - 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet - Google Patents

3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet

Info

Publication number
DK1025114T3
DK1025114T3 DK98946087T DK98946087T DK1025114T3 DK 1025114 T3 DK1025114 T3 DK 1025114T3 DK 98946087 T DK98946087 T DK 98946087T DK 98946087 T DK98946087 T DK 98946087T DK 1025114 T3 DK1025114 T3 DK 1025114T3
Authority
DK
Denmark
Prior art keywords
modified
antibacterial activity
substituted erythromycin
ketolide derivatives
erythromycin ketolide
Prior art date
Application number
DK98946087T
Other languages
Danish (da)
English (en)
Inventor
Yat Sun Or
Zhenkun Ma
Daniel T Chu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1025114T3 publication Critical patent/DK1025114T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
DK98946087T 1997-09-30 1998-09-16 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet DK1025114T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94087197A 1997-09-30 1997-09-30
US13312198A 1998-08-12 1998-08-12
PCT/US1998/019311 WO1999016779A1 (en) 1997-09-30 1998-09-16 3'-n-modified 6-o-substituted erythromycin ketolide derivatives having antibacterial activity

Publications (1)

Publication Number Publication Date
DK1025114T3 true DK1025114T3 (da) 2004-07-05

Family

ID=26831064

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98946087T DK1025114T3 (da) 1997-09-30 1998-09-16 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet

Country Status (22)

Country Link
EP (1) EP1025114B1 (tr)
JP (1) JP2001518476A (tr)
KR (1) KR20010030807A (tr)
CN (1) CN1271363A (tr)
AR (1) AR015727A1 (tr)
AT (1) ATE260293T1 (tr)
AU (1) AU737310B2 (tr)
BG (1) BG104340A (tr)
BR (1) BR9812577A (tr)
CA (1) CA2303930A1 (tr)
CO (1) CO4990958A1 (tr)
DE (1) DE69821964T2 (tr)
DK (1) DK1025114T3 (tr)
ES (1) ES2217579T3 (tr)
HU (1) HUP0004579A3 (tr)
IL (1) IL134608A0 (tr)
NO (1) NO20001439L (tr)
PL (1) PL339575A1 (tr)
PT (1) PT1025114E (tr)
SK (1) SK4562000A3 (tr)
TR (1) TR200000805T2 (tr)
WO (1) WO1999016779A1 (tr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
KR20020007374A (ko) * 1999-04-16 2002-01-26 추후제출 매크롤라이드 항감염제
US6355620B1 (en) * 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
CN1197870C (zh) * 2000-08-14 2005-04-20 大正制药株式会社 一种红霉素衍生物的制备方法及其中间体
US20020111317A1 (en) * 2000-09-25 2002-08-15 Leonard Katz Sixteen-membered macrolide compounds
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
CN1950388A (zh) * 2004-02-27 2007-04-18 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
EP1794171A2 (en) * 2004-07-28 2007-06-13 Ranbaxy Laboratories, Ltd. Ketolide derivatives as antibacterial agents
EP1807439A2 (en) * 2004-10-25 2007-07-18 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
WO2006129257A2 (en) * 2005-05-30 2006-12-07 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EP1934237A2 (en) 2005-08-24 2008-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
EP1928893A2 (en) 2005-08-24 2008-06-11 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
WO2007060518A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
RU2455308C2 (ru) * 2006-05-01 2012-07-10 Тайсо Фармасьютикал Ко., Лтд. Макролидные производные
WO2008099368A1 (en) * 2007-02-15 2008-08-21 Ranbaxy Laboratories Limited Macrolide derivatives as antibacterial agents
WO2008111020A2 (en) * 2007-03-14 2008-09-18 Ranbaxy Laboratories Limited Macrolide derivatives as antibacterial agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
IL123551A0 (en) * 1995-11-08 1998-10-30 Abbott Lab Tricyclic erythromycin derivatives

Also Published As

Publication number Publication date
DE69821964D1 (de) 2004-04-01
CA2303930A1 (en) 1999-04-08
BR9812577A (pt) 2000-10-17
EP1025114A1 (en) 2000-08-09
AU9317698A (en) 1999-04-23
CO4990958A1 (es) 2000-12-26
PT1025114E (pt) 2004-07-30
BG104340A (en) 2001-01-31
KR20010030807A (ko) 2001-04-16
ATE260293T1 (de) 2004-03-15
DE69821964T2 (de) 2004-12-30
CN1271363A (zh) 2000-10-25
SK4562000A3 (en) 2000-09-12
JP2001518476A (ja) 2001-10-16
EP1025114B1 (en) 2004-02-25
HUP0004579A3 (en) 2001-11-28
AU737310B2 (en) 2001-08-16
ES2217579T3 (es) 2004-11-01
IL134608A0 (en) 2001-04-30
AR015727A1 (es) 2001-05-16
NO20001439L (no) 2000-05-29
TR200000805T2 (tr) 2000-10-23
WO1999016779A1 (en) 1999-04-08
HUP0004579A2 (hu) 2001-05-28
NO20001439D0 (no) 2000-03-20
PL339575A1 (en) 2000-12-18

Similar Documents

Publication Publication Date Title
DK1025114T3 (da) 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet
IS5251A (is) 9-oxím erýþrómýsín afleiður
NO993876D0 (no) 3'-N-oksid, 3'-N-dimetylamin, 9-oksim erytromycin A derivater
ZA977474B (en) 6-O-substituted ketolides having antibacterial activity.
ATE310742T1 (de) C-4ß-SUBSTITUTIERTE MACROLID-DERIVATE
LV11547A (lv) Makrolidi ar imunodepresantu aktivitati
DK0941998T3 (da) 3,6-ketalmakrolidantibiotika
ATE377018T1 (de) Erythromycinderivate
NO20005015L (no) 15-ring-laktamketolider med antibakteriell aktivitet
ATE257484T1 (de) 6,9-verbrückte erythromycin-derivate
DK1027362T3 (da) 2-halogen-6-O-substituerede ketolidderivater
ATE239750T1 (de) 6,11-verbrückte erythromycinderivate
DK0797579T3 (da) Erythromycin A-9-O-oxim-derivater udstyret med antibiotisk aktivitet
ZA988808B (en) 3'-N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
SI1025114T1 (en) 3'-n-modified 6-o-substituted erythromycin ketolide derivatives having antibacterial activity
PT984975E (pt) Derivados de eritromicina multiciclicos
BR1100639B1 (pt) cetolÍdeos 6-o-substituÍdos possuindo atividade antibacteriana.
SI1161438T1 (en) 6-o-substituted macrolides having antibacterial activity
SI1100806T1 (en) Erythromycin derivative with antibiotic activity
BR1100453A (pt) derivados de eritromicina
ITMI981775A0 (it) Derivato di eritromicina ad attivita' antibiotica
SI0966477T1 (en) 3'-n-oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives