DK0970077T3 - Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner - Google Patents
Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindionerInfo
- Publication number
- DK0970077T3 DK0970077T3 DK98916974T DK98916974T DK0970077T3 DK 0970077 T3 DK0970077 T3 DK 0970077T3 DK 98916974 T DK98916974 T DK 98916974T DK 98916974 T DK98916974 T DK 98916974T DK 0970077 T3 DK0970077 T3 DK 0970077T3
- Authority
- DK
- Denmark
- Prior art keywords
- thiazolidinediones
- novel
- preparation
- improved process
- improved
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19711616A DE19711616A1 (de) | 1997-03-20 | 1997-03-20 | Verbessertes Verfahren zur Herstellung von Thiazolidindionen |
PCT/EP1998/001535 WO1998042704A1 (de) | 1997-03-20 | 1998-03-17 | Verbessertes verfahren zur herstellung von thiazolidindionen und neue thiazolidindione |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0970077T3 true DK0970077T3 (da) | 2003-09-01 |
Family
ID=7824011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98916974T DK0970077T3 (da) | 1997-03-20 | 1998-03-17 | Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner |
Country Status (26)
Country | Link |
---|---|
US (2) | US6258832B1 (zh) |
EP (1) | EP0970077B1 (zh) |
JP (2) | JP3484200B2 (zh) |
KR (1) | KR100340353B1 (zh) |
CN (1) | CN1105718C (zh) |
AR (1) | AR012124A1 (zh) |
AT (1) | ATE240324T1 (zh) |
AU (1) | AU726048B2 (zh) |
BR (1) | BR9808029A (zh) |
CA (1) | CA2285208C (zh) |
DE (2) | DE19711616A1 (zh) |
DK (1) | DK0970077T3 (zh) |
ES (1) | ES2198053T3 (zh) |
HK (1) | HK1025965A1 (zh) |
HU (1) | HUP0001551A3 (zh) |
IL (1) | IL131772A (zh) |
NO (1) | NO313292B1 (zh) |
NZ (1) | NZ337608A (zh) |
PL (1) | PL192201B1 (zh) |
PT (1) | PT970077E (zh) |
RS (1) | RS49771B (zh) |
RU (1) | RU2181724C2 (zh) |
TR (1) | TR199902197T2 (zh) |
TW (1) | TW487707B (zh) |
WO (1) | WO1998042704A1 (zh) |
ZA (1) | ZA982326B (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE319702T1 (de) | 1999-08-02 | 2006-03-15 | Verfahren zur herstellung von benzothiophen- derivaten | |
US6531609B2 (en) | 2000-04-14 | 2003-03-11 | Hoffmann-La Roche Inc. | Process for the preparation of thiazolidinedione derivatives |
FR2820742B1 (fr) | 2001-02-14 | 2005-03-11 | Ppg Sipsy | Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine |
FR2820741A1 (fr) * | 2001-02-14 | 2002-08-16 | Ppg Sipsy | Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine |
US7323481B2 (en) * | 2001-04-06 | 2008-01-29 | Hoffmann-La Roche Inc. | Thiazolidinediones alone or in combination with other therapeutic agents for inhibiting or reducing tumour growth |
IL158589A0 (en) * | 2001-05-15 | 2004-05-12 | Hoffmann La Roche | Carboxylic acid substituted oxazole derivatives for use as ppar-alpha and -gamma activators in the treatment of diabetes |
MXPA04012840A (es) * | 2002-07-03 | 2005-02-24 | Hoffmann La Roche | Derivados de oxazol y su uso como sensibilizadores a la insulina. |
RU2296754C2 (ru) * | 2002-08-30 | 2007-04-10 | Ф.Хоффманн-Ля Рош Аг | НОВЫЕ СОЕДИНЕНИЯ 2-АРИЛТИАЗОЛА В КАЧЕСТВЕ АГОНИСТОВ PPAR α И PPAR γ |
EP1539746B1 (en) * | 2002-09-12 | 2006-11-15 | F. Hoffmann-La Roche Ag | N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes |
EP1567523B1 (en) * | 2002-11-25 | 2008-08-20 | F.Hoffmann-La Roche Ag | Indolyl derivatives |
CN1809562A (zh) * | 2003-06-26 | 2006-07-26 | 霍夫曼-拉罗奇有限公司 | 制备胰岛素敏化剂及其中间体化合物的方法 |
US20210172618A1 (en) | 2019-12-10 | 2021-06-10 | Lg Electonics Inc. | Air management apparatus or device |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
US4703052A (en) | 1985-05-21 | 1987-10-27 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
GB8713861D0 (en) | 1987-06-13 | 1987-07-15 | Beecham Group Plc | Compounds |
ES2137915T3 (es) * | 1987-09-04 | 2000-01-01 | Beecham Group Plc | Derivados de tiazolidindiona sustituida. |
US5330998A (en) | 1988-03-08 | 1994-07-19 | Pfizer Inc. | Thiazolidinedione derivatives as hypoglycemic agents |
US5061717A (en) * | 1988-03-08 | 1991-10-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
HU217432B (hu) | 1988-03-08 | 2000-01-28 | Pfizer Inc. | Eljárás tiazolidin-dion-származékok és az ezeket tartalmazó gyógyszerkészítmények előállítására, a vegyületek és a készítmények |
MX15171A (es) | 1988-03-08 | 1993-05-01 | Pfizer | Derivados de tiazolidinodiona hipoglicemicos |
ATE205206T1 (de) * | 1990-04-27 | 2001-09-15 | Sankyo Co | Benzylidenthiazolidinderivate, ihre herstellung und ihre anwendung als lipidperoxid-inhibitoren |
KR930701420A (ko) | 1990-08-23 | 1993-06-11 | 알렌 제이. 스피겔 | 혈당저하제로서의 하이드록시우레아 유도체 |
CA2122712C (en) * | 1991-12-20 | 1999-09-21 | Joel Edward Huber | A reduction method for substituted 5-methylene-thiazolidinediones |
FR2688220A1 (fr) | 1992-03-06 | 1993-09-10 | Adir | Nouveaux derives de thiazolidine-2,4-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
DE4317320A1 (de) * | 1993-05-25 | 1994-12-01 | Boehringer Mannheim Gmbh | Neue Thiazolidindione und diese enthaltende Arzneimittel |
EP0684242B1 (en) | 1993-12-27 | 1999-05-06 | Japan Tobacco Inc. | Isoxazolidinedione derivative and use thereof |
-
1997
- 1997-03-20 DE DE19711616A patent/DE19711616A1/de not_active Withdrawn
-
1998
- 1998-03-17 DK DK98916974T patent/DK0970077T3/da active
- 1998-03-17 RS YUP-466/99A patent/RS49771B/sr unknown
- 1998-03-17 EP EP98916974A patent/EP0970077B1/de not_active Expired - Lifetime
- 1998-03-17 RU RU99122023/04A patent/RU2181724C2/ru not_active IP Right Cessation
- 1998-03-17 DE DE59808365T patent/DE59808365D1/de not_active Expired - Fee Related
- 1998-03-17 PT PT98916974T patent/PT970077E/pt unknown
- 1998-03-17 AT AT98916974T patent/ATE240324T1/de not_active IP Right Cessation
- 1998-03-17 AU AU70361/98A patent/AU726048B2/en not_active Ceased
- 1998-03-17 KR KR1019997008445A patent/KR100340353B1/ko not_active IP Right Cessation
- 1998-03-17 NZ NZ337608A patent/NZ337608A/en unknown
- 1998-03-17 HU HU0001551A patent/HUP0001551A3/hu unknown
- 1998-03-17 TR TR1999/02197T patent/TR199902197T2/xx unknown
- 1998-03-17 ES ES98916974T patent/ES2198053T3/es not_active Expired - Lifetime
- 1998-03-17 WO PCT/EP1998/001535 patent/WO1998042704A1/de active IP Right Grant
- 1998-03-17 TW TW087103935A patent/TW487707B/zh not_active IP Right Cessation
- 1998-03-17 BR BR9808029-6A patent/BR9808029A/pt not_active Application Discontinuation
- 1998-03-17 CA CA002285208A patent/CA2285208C/en not_active Expired - Fee Related
- 1998-03-17 CN CN98803388A patent/CN1105718C/zh not_active Expired - Fee Related
- 1998-03-17 JP JP54484098A patent/JP3484200B2/ja not_active Expired - Fee Related
- 1998-03-17 US US09/381,247 patent/US6258832B1/en not_active Expired - Fee Related
- 1998-03-17 IL IL13177298A patent/IL131772A/en not_active IP Right Cessation
- 1998-03-17 PL PL335903A patent/PL192201B1/pl not_active IP Right Cessation
- 1998-03-19 ZA ZA9802326A patent/ZA982326B/xx unknown
- 1998-03-20 AR ARP980101266A patent/AR012124A1/es active IP Right Grant
-
1999
- 1999-09-17 NO NO19994505A patent/NO313292B1/no unknown
-
2000
- 2000-08-18 HK HK00105205A patent/HK1025965A1/xx not_active IP Right Cessation
-
2001
- 2001-02-14 US US09/783,494 patent/US6441185B2/en not_active Expired - Fee Related
-
2003
- 2003-08-21 JP JP2003297751A patent/JP2004067697A/ja active Pending
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