DK0970077T3 - Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner - Google Patents

Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Info

Publication number
DK0970077T3
DK0970077T3 DK98916974T DK98916974T DK0970077T3 DK 0970077 T3 DK0970077 T3 DK 0970077T3 DK 98916974 T DK98916974 T DK 98916974T DK 98916974 T DK98916974 T DK 98916974T DK 0970077 T3 DK0970077 T3 DK 0970077T3
Authority
DK
Denmark
Prior art keywords
thiazolidinediones
novel
preparation
improved process
improved
Prior art date
Application number
DK98916974T
Other languages
English (en)
Inventor
Hans-Peter Wolff
Ernst-Christian Witte
Hans-Frieder Kuehnle
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Application granted granted Critical
Publication of DK0970077T3 publication Critical patent/DK0970077T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK98916974T 1997-03-20 1998-03-17 Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner DK0970077T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19711616A DE19711616A1 (de) 1997-03-20 1997-03-20 Verbessertes Verfahren zur Herstellung von Thiazolidindionen
PCT/EP1998/001535 WO1998042704A1 (de) 1997-03-20 1998-03-17 Verbessertes verfahren zur herstellung von thiazolidindionen und neue thiazolidindione

Publications (1)

Publication Number Publication Date
DK0970077T3 true DK0970077T3 (da) 2003-09-01

Family

ID=7824011

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98916974T DK0970077T3 (da) 1997-03-20 1998-03-17 Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner

Country Status (26)

Country Link
US (2) US6258832B1 (da)
EP (1) EP0970077B1 (da)
JP (2) JP3484200B2 (da)
KR (1) KR100340353B1 (da)
CN (1) CN1105718C (da)
AR (1) AR012124A1 (da)
AT (1) ATE240324T1 (da)
AU (1) AU726048B2 (da)
BR (1) BR9808029A (da)
CA (1) CA2285208C (da)
DE (2) DE19711616A1 (da)
DK (1) DK0970077T3 (da)
ES (1) ES2198053T3 (da)
HK (1) HK1025965A1 (da)
HU (1) HUP0001551A3 (da)
IL (1) IL131772A (da)
NO (1) NO313292B1 (da)
NZ (1) NZ337608A (da)
PL (1) PL192201B1 (da)
PT (1) PT970077E (da)
RS (1) RS49771B (da)
RU (1) RU2181724C2 (da)
TR (1) TR199902197T2 (da)
TW (1) TW487707B (da)
WO (1) WO1998042704A1 (da)
ZA (1) ZA982326B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE319702T1 (de) 1999-08-02 2006-03-15 Verfahren zur herstellung von benzothiophen- derivaten
US6531609B2 (en) * 2000-04-14 2003-03-11 Hoffmann-La Roche Inc. Process for the preparation of thiazolidinedione derivatives
FR2820741A1 (fr) * 2001-02-14 2002-08-16 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
FR2820742B1 (fr) 2001-02-14 2005-03-11 Ppg Sipsy Procede de preparation de composes derives de thiazolidinedione, d'oxazolidinedione ou d'hydantoine
JP2004525168A (ja) * 2001-04-06 2004-08-19 エフ.ホフマン−ラ ロシュ アーゲー 腫瘍の成長を抑制もしくは減少するための単独または他の治療薬との組合わせでのチアゾリジンジオン
IL158589A0 (en) * 2001-05-15 2004-05-12 Hoffmann La Roche Carboxylic acid substituted oxazole derivatives for use as ppar-alpha and -gamma activators in the treatment of diabetes
WO2004005266A1 (en) * 2002-07-03 2004-01-15 F. Hoffmann-La Roche Ag Oxazole derivatives and their use as insulin sensitizers
PT1537091E (pt) * 2002-08-30 2010-11-11 Hoffmann La Roche Novos compostos de 2-ariltiazole como agonistas de ppar-alfa e de ppar-gama
CN100577660C (zh) * 2002-09-12 2010-01-06 霍夫曼-拉罗奇有限公司 作为ppar激动剂用于治疗糖尿病的n-取代-1h-吲哚-5-丙酸化合物
WO2004048371A1 (en) * 2002-11-25 2004-06-10 F.Hoffmann-La Roche Ag Indolyl derivatives
WO2005000844A1 (en) * 2003-06-26 2005-01-06 F. Hoffmann-La Roche Ag Process for the preparation of insulin sensitizer and intermediate compound thereof
US11566796B2 (en) 2019-12-10 2023-01-31 Lg Electronics Inc. Air management apparatus and method thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
HU210339B (en) 1985-05-21 1995-03-28 Pfizer Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
GB8713861D0 (en) 1987-06-13 1987-07-15 Beecham Group Plc Compounds
EP0306228B1 (en) * 1987-09-04 1999-11-17 Beecham Group Plc Substituted thiazolidinedione derivatives
US5330998A (en) 1988-03-08 1994-07-19 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
MX15171A (es) 1988-03-08 1993-05-01 Pfizer Derivados de tiazolidinodiona hipoglicemicos
WO1989008650A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione hypoglycemic agents
WO1989008652A1 (en) 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
ATE205206T1 (de) * 1990-04-27 2001-09-15 Sankyo Co Benzylidenthiazolidinderivate, ihre herstellung und ihre anwendung als lipidperoxid-inhibitoren
US5334604A (en) 1990-08-23 1994-08-02 Pfizer Inc. Hypoglycemic hydroxyurea derivatives
CA2122712C (en) * 1991-12-20 1999-09-21 Joel Edward Huber A reduction method for substituted 5-methylene-thiazolidinediones
FR2688220A1 (fr) 1992-03-06 1993-09-10 Adir Nouveaux derives de thiazolidine-2,4-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
ATE179709T1 (de) 1993-12-27 1999-05-15 Japan Tobacco Inc Isoxazolidindionderivate und deren verwendung

Also Published As

Publication number Publication date
RU2181724C2 (ru) 2002-04-27
NZ337608A (en) 2001-05-25
AU726048B2 (en) 2000-10-26
KR20000076344A (ko) 2000-12-26
NO313292B1 (no) 2002-09-09
JP2000512312A (ja) 2000-09-19
DE19711616A1 (de) 1998-09-24
HK1025965A1 (en) 2000-12-01
TW487707B (en) 2002-05-21
NO994505D0 (no) 1999-09-17
US20010008902A1 (en) 2001-07-19
EP0970077B1 (de) 2003-05-14
CN1105718C (zh) 2003-04-16
PL335903A1 (en) 2000-05-22
WO1998042704A1 (de) 1998-10-01
AR012124A1 (es) 2000-09-27
BR9808029A (pt) 2000-03-08
ES2198053T3 (es) 2004-01-16
CA2285208A1 (en) 1998-10-01
JP2004067697A (ja) 2004-03-04
CA2285208C (en) 2003-07-08
HUP0001551A2 (hu) 2000-11-28
NO994505L (no) 1999-11-17
DE59808365D1 (de) 2003-06-18
PL192201B1 (pl) 2006-09-29
TR199902197T2 (xx) 1999-12-21
CN1250448A (zh) 2000-04-12
US6441185B2 (en) 2002-08-27
ZA982326B (en) 1999-09-20
KR100340353B1 (ko) 2002-06-12
IL131772A (en) 2002-09-12
AU7036198A (en) 1998-10-20
RS49771B (sr) 2008-06-05
YU46699A (sh) 2002-06-19
US6258832B1 (en) 2001-07-10
ATE240324T1 (de) 2003-05-15
PT970077E (pt) 2003-08-29
JP3484200B2 (ja) 2004-01-06
HUP0001551A3 (en) 2000-12-28
IL131772A0 (en) 2001-03-19
EP0970077A1 (de) 2000-01-12

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