DK0948527T3 - Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse - Google Patents
Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disseInfo
- Publication number
- DK0948527T3 DK0948527T3 DK97952998T DK97952998T DK0948527T3 DK 0948527 T3 DK0948527 T3 DK 0948527T3 DK 97952998 T DK97952998 T DK 97952998T DK 97952998 T DK97952998 T DK 97952998T DK 0948527 T3 DK0948527 T3 DK 0948527T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- cylosporin
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9615956A FR2757522B1 (fr) | 1996-12-24 | 1996-12-24 | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
PCT/FR1997/002405 WO1998028329A1 (fr) | 1996-12-24 | 1997-12-23 | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0948527T3 true DK0948527T3 (da) | 2002-09-16 |
Family
ID=9499089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97952998T DK0948527T3 (da) | 1996-12-24 | 1997-12-23 | Cylosporinderivater, fremstilling af disse og farmaceutiske præparater indeholdende disse |
Country Status (14)
Country | Link |
---|---|
US (1) | US5965527A (ja) |
EP (1) | EP0948527B1 (ja) |
JP (1) | JP4172822B2 (ja) |
AT (1) | ATE218580T1 (ja) |
AU (1) | AU5669298A (ja) |
DE (1) | DE69713148D1 (ja) |
DK (1) | DK0948527T3 (ja) |
ES (1) | ES2178037T3 (ja) |
FR (1) | FR2757522B1 (ja) |
MA (1) | MA26459A1 (ja) |
PT (1) | PT948527E (ja) |
TN (1) | TNSN97211A1 (ja) |
WO (1) | WO1998028329A1 (ja) |
ZA (1) | ZA9711606B (ja) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE254630T1 (de) * | 1998-06-12 | 2003-12-15 | Chem Ag C | Cyclosporine |
JP4350898B2 (ja) | 1998-07-01 | 2009-10-21 | デビオファーム・ソシエテ・アノニム | 活性の特徴が改善された新規のシクロスポリン |
US6254860B1 (en) | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
KR100978836B1 (ko) * | 2001-10-19 | 2010-08-30 | 이소테크니카 인코포레이티드 | 신규한 시클로스포린 유사체 미세유화액 예비농축물 |
DK1714977T3 (da) | 2001-10-19 | 2009-07-06 | Isotechnika Inc | Syntese af cyclosporinanaloger |
US6987090B2 (en) * | 2002-05-09 | 2006-01-17 | Lg Household & Health Care Ltd. | Use of 3-position cyclosporin derivatives for hair growth |
KR20040039622A (ko) * | 2002-11-04 | 2004-05-12 | 주식회사 엘지생활건강 | 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제 |
GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
ES2357587T3 (es) | 2004-10-01 | 2011-04-27 | Debiopharm S.A. | Uso de (d-meala)3-(etval)4-ciclosporina para el tratamiento de infección por hepatitis c. |
RU2399628C2 (ru) * | 2004-10-01 | 2010-09-20 | Скайнексис, Инк. | Производные циклоспорина, замещенные 3-эфиром и 3-тиоэфиром, для лечения и профилактики инфекционного гепатита с |
US7196161B2 (en) * | 2004-10-01 | 2007-03-27 | Scynexis Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
EP1830871A1 (en) * | 2004-12-23 | 2007-09-12 | Novartis AG | Compositions for hcv treatment |
CN101084005A (zh) * | 2004-12-23 | 2007-12-05 | 诺瓦提斯公司 | 用于黄病毒科治疗的化合物 |
WO2007041631A1 (en) | 2005-09-30 | 2007-04-12 | Scynexis, Inc. | ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION |
EP1933859A2 (en) * | 2005-09-30 | 2008-06-25 | Scynexis, Inc. | Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection |
US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
CN101511357B (zh) | 2006-05-19 | 2011-11-02 | 西尼克斯公司 | 环孢菌素类化合物及其组合物在制备治疗和预防眼部疾病的药物中的应用 |
EP2027761A1 (fr) * | 2006-06-02 | 2009-02-25 | Claude Annie Perrichon | Gestion des electrons actifs |
CN101557819A (zh) * | 2006-10-12 | 2009-10-14 | 诺瓦提斯公司 | 修饰的环孢素的用途 |
WO2008069917A2 (en) | 2006-11-20 | 2008-06-12 | Scynexis, Inc. | Novel cyclic peptides |
US20080255038A1 (en) * | 2007-04-11 | 2008-10-16 | Samuel Earl Hopkins | Pharmaceutical compositions |
US8394763B2 (en) | 2007-09-26 | 2013-03-12 | Oregon Health & Science University | Cyclic undecapeptides and derivatives as multiple sclerosis therapies |
WO2010002428A2 (en) | 2008-06-06 | 2010-01-07 | Scynexis, Inc. | Novel macrocyclic peptides |
WO2009148615A1 (en) * | 2008-06-06 | 2009-12-10 | Scynexis, Inc. | Cyclosporin analogs and their use in the treatment of hcv infections |
KR20110031973A (ko) * | 2008-07-10 | 2011-03-29 | 알러간, 인코포레이티드 | 눈 및 피부의 질환 및 상태를 치료하기 위한 사이클로스포린 유도체 |
DE102008060549A1 (de) | 2008-12-04 | 2010-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung |
CN102307892A (zh) | 2008-12-31 | 2012-01-04 | 西尼克斯公司 | 环孢菌素a的衍生物 |
JP2012528163A (ja) | 2009-05-27 | 2012-11-12 | アラーガン、インコーポレイテッド | 炎症性疾患および状態を処置するためのシクロスポリン誘導体 |
GB0912584D0 (en) * | 2009-07-20 | 2009-08-26 | Ucl Business Plc | Cyclosporin conjugates |
US9217015B2 (en) * | 2010-07-16 | 2015-12-22 | S&T Global Inc. | Cyclosporin derivatives for the treatment and prevention of a viral infection |
CN103153330B (zh) * | 2010-08-12 | 2017-08-18 | 美国科技环球有限公司 | 新的环孢霉素衍生物在病毒感染的治疗和预防中的应用 |
JP5805773B2 (ja) | 2010-10-12 | 2015-11-10 | アラーガン、インコーポレイテッドAllergan,Incorporated | シクロスポリンアナログ |
EP2627664B1 (en) | 2010-10-12 | 2018-04-04 | Allergan, Inc. | Cyclosporin analogs |
US9890198B2 (en) | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
MX353720B (es) | 2010-12-15 | 2018-01-25 | Contravir Pharmaceuticals Inc | Moleculas analogas de ciclosporina modificadas en el aminoacido 1 y 3. |
EP2705856A1 (en) | 2012-09-07 | 2014-03-12 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. | Compounds for the treatment of neurodegenerative disorders |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0194972B1 (en) * | 1985-03-11 | 1992-07-29 | Sandoz Ag | Novel cyclosporins |
US4814323A (en) * | 1986-03-25 | 1989-03-21 | Andrieu J M | Process for the treatment and the prevention of AIDS and other disorders induced by the LAV/HTLV III virus |
EP0484281B2 (en) * | 1990-11-02 | 2000-11-22 | Novartis AG | Cyclosporins |
ATE209216T1 (de) * | 1995-07-17 | 2001-12-15 | Chem Ag C | Cyclosporin-derivate mit anti-hiv-wirkung |
-
1996
- 1996-12-24 FR FR9615956A patent/FR2757522B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-19 MA MA24908A patent/MA26459A1/fr unknown
- 1997-12-23 DE DE69713148T patent/DE69713148D1/de not_active Expired - Lifetime
- 1997-12-23 WO PCT/FR1997/002405 patent/WO1998028329A1/fr active IP Right Grant
- 1997-12-23 JP JP52848998A patent/JP4172822B2/ja not_active Expired - Fee Related
- 1997-12-23 EP EP97952998A patent/EP0948527B1/fr not_active Expired - Lifetime
- 1997-12-23 DK DK97952998T patent/DK0948527T3/da active
- 1997-12-23 US US08/996,699 patent/US5965527A/en not_active Expired - Fee Related
- 1997-12-23 ES ES97952998T patent/ES2178037T3/es not_active Expired - Lifetime
- 1997-12-23 AU AU56692/98A patent/AU5669298A/en not_active Abandoned
- 1997-12-23 ZA ZA9711606A patent/ZA9711606B/xx unknown
- 1997-12-23 PT PT97952998T patent/PT948527E/pt unknown
- 1997-12-23 TN TNTNSN97211A patent/TNSN97211A1/fr unknown
- 1997-12-23 AT AT97952998T patent/ATE218580T1/de active
Also Published As
Publication number | Publication date |
---|---|
EP0948527A1 (fr) | 1999-10-13 |
JP4172822B2 (ja) | 2008-10-29 |
AU5669298A (en) | 1998-07-17 |
DE69713148D1 (de) | 2002-07-11 |
FR2757522B1 (fr) | 1999-01-29 |
EP0948527B1 (fr) | 2002-06-05 |
ATE218580T1 (de) | 2002-06-15 |
ZA9711606B (en) | 1998-06-25 |
WO1998028329A1 (fr) | 1998-07-02 |
ES2178037T3 (es) | 2002-12-16 |
US5965527A (en) | 1999-10-12 |
TNSN97211A1 (fr) | 2005-03-15 |
MA26459A1 (fr) | 2004-12-20 |
PT948527E (pt) | 2002-11-29 |
JP2001507346A (ja) | 2001-06-05 |
FR2757522A1 (fr) | 1998-06-26 |
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