KR100361933B1
(ko)
|
1993-09-08 |
2003-02-14 |
라 졸라 파마슈티칼 컴파니 |
화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트
|
US5965566A
(en)
*
|
1993-10-20 |
1999-10-12 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
US6096336A
(en)
*
|
1996-01-30 |
2000-08-01 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
KR100561788B1
(ko)
*
|
1996-03-12 |
2006-09-20 |
피지-티엑스엘 컴파니,엘.피. |
수용성파클리탁셀전구약물을포함하는조성물및이러한조성물을포함하는이식가능한의료장치
|
US6214966B1
(en)
*
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US20050158273A1
(en)
*
|
1997-09-25 |
2005-07-21 |
Harris J. M. |
Soluble, degradable polyethylene glycol) derivatives for controllable release of bound molecules into solution
|
US6011042A
(en)
*
|
1997-10-10 |
2000-01-04 |
Enzon, Inc. |
Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
|
US6111107A
(en)
*
|
1997-11-20 |
2000-08-29 |
Enzon, Inc. |
High yield method for stereoselective acylation of tertiary alcohols
|
CA2312975C
(en)
|
1997-12-17 |
2012-08-21 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
US6180095B1
(en)
*
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
CA2316834C
(en)
*
|
1998-01-07 |
2006-01-03 |
Shearwater Polymers, Inc. |
Degradable heterobifunctional poly(ethylene glycol) acrylates and gels and conjugates derived therefrom
|
US6153655A
(en)
*
|
1998-04-17 |
2000-11-28 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
AU760381B2
(en)
*
|
1998-04-28 |
2003-05-15 |
Laboratoires Serono Sa |
PEG-LHRH analog conjugates
|
US7953788B2
(en)
*
|
2001-09-29 |
2011-05-31 |
Siebel Systems, Inc. |
System and method for queuing data for an application server
|
CN1762990A
(zh)
*
|
1999-06-08 |
2006-04-26 |
拉卓拉药物公司 |
包含氨基氧基的化合价平台分子
|
WO2001005819A1
(en)
*
|
1999-07-15 |
2001-01-25 |
Kuhnil Pharm. Co., Ltd. |
Novel water soluble-cyclosporine conjugated compounds
|
US6228855B1
(en)
*
|
1999-08-03 |
2001-05-08 |
The Stehlin Foundation For Cancer Research |
Aromatic esters of camptothecins and methods to treat cancers
|
US6352996B1
(en)
|
1999-08-03 |
2002-03-05 |
The Stehlin Foundation For Cancer Research |
Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
|
US6380405B1
(en)
*
|
1999-09-13 |
2002-04-30 |
Nobex Corporation |
Taxane prodrugs
|
US6541508B2
(en)
|
1999-09-13 |
2003-04-01 |
Nobex Corporation |
Taxane prodrugs
|
US6713454B1
(en)
|
1999-09-13 |
2004-03-30 |
Nobex Corporation |
Prodrugs of etoposide and etoposide analogs
|
US6376470B1
(en)
*
|
1999-09-23 |
2002-04-23 |
Enzon, Inc. |
Polymer conjugates of ara-C and ara-C derivatives
|
EP2289549A3
(en)
|
1999-10-01 |
2011-06-15 |
Immunogen, Inc. |
Immunoconjugates for treating cancer
|
DK1259562T3
(da)
*
|
1999-12-22 |
2006-04-18 |
Nektar Therapeutics Al Corp |
Sterisk hindrede derivater af vandoplöselige polymerer
|
AU2001257577A1
(en)
|
2000-02-28 |
2001-09-03 |
Shearwater Corporation |
Water-soluble polymer conjugates of artelinic acid
|
AU2001268228A1
(en)
|
2000-06-08 |
2001-12-17 |
La Jolla Pharmaceutical Company |
Multivalent platform molecules comprising high molecular weight polyethylene oxide
|
AU2001273387A1
(en)
*
|
2000-07-12 |
2002-01-21 |
Gryphon Therapeutics, Inc. |
Polymer-modified bioactive synthetic chemokines, and methods for their manufacture and use
|
US7118737B2
(en)
|
2000-09-08 |
2006-10-10 |
Amylin Pharmaceuticals, Inc. |
Polymer-modified synthetic proteins
|
CN1454097A
(zh)
*
|
2000-09-08 |
2003-11-05 |
格莱风治疗公司 |
聚合物修饰的合成的蛋白质类
|
US6436386B1
(en)
|
2000-11-14 |
2002-08-20 |
Shearwater Corporation |
Hydroxyapatite-targeting poly (ethylene glycol) and related polymers
|
US7829074B2
(en)
*
|
2001-10-18 |
2010-11-09 |
Nektar Therapeutics |
Hydroxypatite-targeting poly(ethylene glycol) and related polymers
|
AU2002251988A1
(en)
*
|
2001-02-20 |
2002-09-04 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
JP2004530736A
(ja)
*
|
2001-02-20 |
2004-10-07 |
エンゾン ファーマシューティカルズ,インコーポレーテッド |
末端分枝高分子リンカーおよびそれを含む高分子複合体
|
US20040077835A1
(en)
*
|
2001-07-12 |
2004-04-22 |
Robin Offord |
Chemokine receptor modulators, production and use
|
CA2465206C
(en)
*
|
2001-11-09 |
2010-01-26 |
Enzon, Inc. |
Polymeric thiol-linked prodrugs
|
GB0202906D0
(en)
|
2002-02-07 |
2002-03-27 |
Univ London |
Prevention of myocardial damage
|
DE10209821A1
(de)
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung von Proteinen an ein modifiziertes Polysaccharid
|
DE10209822A1
(de)
*
|
2002-03-06 |
2003-09-25 |
Biotechnologie Ges Mittelhesse |
Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
|
AU2003221291A1
(en)
*
|
2002-03-13 |
2003-09-22 |
Beijing Jiankai Technology Co., Ltd. |
Hydrophilic polymer derivate with y type branch and preparation method of it medical composite comprising above compound
|
EP1494757A2
(en)
*
|
2002-04-04 |
2005-01-12 |
Enzon, Inc. |
Polymeric acyl derivatives of indoles
|
CN100393724C
(zh)
*
|
2002-07-12 |
2008-06-11 |
中国医学科学院药物研究所 |
20-位酯化的喜树碱衍生物及其制法和其药物组合物与用途
|
US7569214B2
(en)
|
2002-09-09 |
2009-08-04 |
Nektar Therapeutics Al, Corporation |
Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid
|
JP4764630B2
(ja)
|
2002-09-09 |
2011-09-07 |
ネクター セラピューティックス |
水溶性ポリマーアルカナール
|
KR101045422B1
(ko)
*
|
2002-09-11 |
2011-06-30 |
프레제니우스 카비 도이치란트 게엠베하 |
하이드록시알킬 전분 유도체의 제조 방법
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US20040062748A1
(en)
*
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
ES2488841T3
(es)
|
2002-10-31 |
2014-08-29 |
Nippon Kayaku Kabushiki Kaisha |
Derivados de alto peso molecular de camptotecinas
|
WO2004061094A1
(en)
|
2002-12-30 |
2004-07-22 |
Gryphon Therapeutics, Inc. |
Water-soluble thioester and selenoester compounds and methods for making and using the same
|
WO2004082629A2
(en)
*
|
2003-03-17 |
2004-09-30 |
Albany Molecular Research, Inc. |
Novel cyclosporins
|
CA2510040C
(en)
*
|
2003-05-23 |
2012-01-03 |
Nektar Therapeutics Al, Corporation |
Polymeric reagents and polymer-biomolecule conjugates comprising carbamate linkages
|
US7947261B2
(en)
|
2003-05-23 |
2011-05-24 |
Nektar Therapeutics |
Conjugates formed from polymer derivatives having particular atom arrangements
|
US7342114B2
(en)
*
|
2003-07-01 |
2008-03-11 |
California Pacific Medical Center |
Podophyllotoxin derivatives
|
WO2005014655A2
(en)
*
|
2003-08-08 |
2005-02-17 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein
|
BRPI0413450A
(pt)
*
|
2003-08-08 |
2006-10-17 |
Fresenius Kabi De Gmbh |
conjugados de hidroxialquil amido e g-csf
|
US8394365B2
(en)
|
2003-09-17 |
2013-03-12 |
Nektar Therapeutics |
Multi-arm polymer prodrugs
|
KR101200729B1
(ko)
*
|
2003-09-17 |
2012-11-13 |
넥타르 테라퓨틱스 |
다분지형 고분자 전구약물
|
US20050153371A1
(en)
*
|
2004-01-07 |
2005-07-14 |
Ambit Biosciences Corporation |
Conjugated small molecules
|
CA2553528C
(en)
*
|
2004-01-21 |
2012-12-04 |
Nektar Therapeutics Al, Corporation |
Method of preparing propionic acid-terminated polymers
|
ES2390885T3
(es)
*
|
2004-03-11 |
2012-11-19 |
Fresenius Kabi Deutschland Gmbh |
Conjugados de hidroxialquilalmidón y una proteína
|
WO2005092928A1
(en)
|
2004-03-11 |
2005-10-06 |
Fresenius Kabi Deutschland Gmbh |
Conjugates of hydroxyalkyl starch and a protein, prepared by reductive amination
|
CN1964979B
(zh)
*
|
2004-04-09 |
2011-07-27 |
中外制药株式会社 |
新颖的水溶性前药
|
US8614228B2
(en)
|
2004-08-11 |
2013-12-24 |
Arqule, Inc. |
Quinone prodrug compositions and methods of use
|
EP1877097B1
(en)
*
|
2004-08-11 |
2012-06-20 |
Arqule, Inc. |
Aminoacid conjugates of beta-lapachone for tumor targeting
|
EP1792927B1
(en)
|
2004-09-22 |
2013-03-06 |
Nippon Kayaku Kabushiki Kaisha |
Novel block copolymer, micelle preparation, and anticancer agent containing the same as active ingredient
|
EP1809656A4
(en)
*
|
2004-09-29 |
2009-03-25 |
Amr Technology Inc |
CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS
|
EP1804823A4
(en)
*
|
2004-09-29 |
2010-06-09 |
Amr Technology Inc |
NEW CYCLOSPORIN ANALOGUE AND ITS PHARMACEUTICAL APPLICATIONS
|
WO2006041631A2
(en)
*
|
2004-10-06 |
2006-04-20 |
Amr Technology, Inc. |
Novel cyclosporin alkynes and their utility as pharmaceutical agents
|
CN101119743B
(zh)
|
2005-01-31 |
2012-09-26 |
株式会社Eci |
免疫增强剂
|
EP1861124A2
(en)
*
|
2005-03-11 |
2007-12-05 |
Fresenius Kabi Deutschland GmbH |
Production of bioactive glycoproteins from inactive starting materials by conjugation with hydroxyalkylstarch
|
JP2008533114A
(ja)
*
|
2005-03-18 |
2008-08-21 |
ユーシーエル ビジネス パブリック リミテッド カンパニー |
メカノ成長因子ペプチドおよびその使用
|
CA2602654A1
(en)
|
2005-04-05 |
2006-10-12 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Method for shielding functional sites or epitopes on proteins
|
TW200744603A
(en)
|
2005-08-22 |
2007-12-16 |
Chugai Pharmaceutical Co Ltd |
Novel anticancer concomitant drug
|
EP1762250A1
(en)
*
|
2005-09-12 |
2007-03-14 |
Fresenius Kabi Deutschland GmbH |
Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine
|
EP1968644B1
(en)
|
2005-12-16 |
2012-06-27 |
Nektar Therapeutics |
Polymer conjugates of glp-1
|
US7671067B2
(en)
*
|
2006-02-09 |
2010-03-02 |
Enzon Pharmaceuticals, Inc. |
Treatment of non-hodgkin's lymphomas with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamtothecin
|
US7462627B2
(en)
*
|
2006-02-09 |
2008-12-09 |
Enzon Pharmaceuticals, Inc. |
Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers
|
KR101513732B1
(ko)
*
|
2006-02-21 |
2015-04-21 |
넥타르 테라퓨틱스 |
분할된 분해가능한 폴리머 및 이로부터 제조된 컨주게이트
|
WO2007111211A1
(ja)
|
2006-03-28 |
2007-10-04 |
Nippon Kayaku Kabushiki Kaisha |
タキサン類の高分子結合体
|
US7696165B2
(en)
*
|
2006-03-28 |
2010-04-13 |
Albany Molecular Research, Inc. |
Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
|
US7696166B2
(en)
*
|
2006-03-28 |
2010-04-13 |
Albany Molecular Research, Inc. |
Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
JP5313129B2
(ja)
|
2006-05-02 |
2013-10-09 |
アロザイン, インコーポレイテッド |
非天然アミノ酸置換ポリペプチド
|
JP5181347B2
(ja)
|
2006-05-18 |
2013-04-10 |
日本化薬株式会社 |
ポドフィロトキシン類の高分子結合体
|
WO2008034019A2
(en)
|
2006-09-13 |
2008-03-20 |
Polymerix Corporation |
Active agents and their oligomers and polymers
|
KR20090057235A
(ko)
*
|
2006-09-15 |
2009-06-04 |
엔존 파마슈티컬즈, 인코포레이티드 |
리신계 폴리머 링커
|
KR20090083334A
(ko)
*
|
2006-09-15 |
2009-08-03 |
엔존 파마슈티컬즈, 인코포레이티드 |
방해된 에스테르 기재 생분해성 링커를 갖는 폴리알킬렌 옥시드
|
US8110559B2
(en)
*
|
2006-09-15 |
2012-02-07 |
Enzon Pharmaceuticals, Inc. |
Hindered ester-based biodegradable linkers for oligonucleotide delivery
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
JP5548364B2
(ja)
*
|
2006-10-03 |
2014-07-16 |
日本化薬株式会社 |
レゾルシノール誘導体の高分子結合体
|
US8334364B2
(en)
|
2006-11-06 |
2012-12-18 |
Nipon Kayaku Kabushiki Kaisha |
High-molecular weight derivative of nucleic acid antimetabolite
|
WO2008056654A1
(en)
|
2006-11-08 |
2008-05-15 |
Nippon Kayaku Kabushiki Kaisha |
Polymeric derivative of nucleic acid metabolic antagonist
|
WO2008066902A2
(en)
|
2006-11-30 |
2008-06-05 |
Nektar Therapeutics Al, Corporation |
Method for preparing a polymer conjugate
|
BRPI0807232A2
(pt)
*
|
2007-02-09 |
2014-04-29 |
Enzon Pharmaceuticals Inc |
Tratamento de cânceres resistentes ou refratários com conjugados poliméricos multi-braços de 7-etil-10-hidroxicamptotecina
|
ES2532656T3
(es)
*
|
2007-04-30 |
2015-03-30 |
Arqule, Inc. |
Compuestos de hidroxi sulfonato de quinona y sus usos
|
CA2707840A1
(en)
*
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
WO2009025669A1
(en)
*
|
2007-08-20 |
2009-02-26 |
Enzon Pharmaceuticals, Inc. |
Polymeric linkers containing pyridyl disulfide moieties
|
USRE46190E1
(en)
|
2007-09-28 |
2016-11-01 |
Nippon Kayaku Kabushiki Kaisha |
High-molecular weight conjugate of steroids
|
WO2009055014A2
(en)
*
|
2007-10-23 |
2009-04-30 |
Nektar Therapeutics Al, Corporation |
Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom
|
EP2070950A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Hydroxyalkyl starch derivatives and process for their preparation
|
EP2070951A1
(en)
*
|
2007-12-14 |
2009-06-17 |
Fresenius Kabi Deutschland GmbH |
Method for producing a hydroxyalkyl starch derivatives with two linkers
|
KR101589582B1
(ko)
|
2008-03-18 |
2016-01-28 |
니폰 가야꾸 가부시끼가이샤 |
생리활성물질의 고분자량 결합체
|
US9149540B2
(en)
|
2008-05-08 |
2015-10-06 |
Nippon Kayaku Kabushiki Kaisha |
Polymer conjugate of folic acid or folic acid derivative
|
MX2011001583A
(es)
|
2008-08-11 |
2011-04-04 |
Nektar Therapeutics |
Conjugados de alcanoato polimericos de multiples brazos.
|
TW201010732A
(en)
*
|
2008-08-29 |
2010-03-16 |
Enzon Pharmaceuticals Inc |
Method of treating RAS associated cancer
|
MX2011003117A
(es)
|
2008-09-19 |
2011-04-21 |
Nektar Therapeutics |
Conjugados polimericos de peptidos terapeuticos.
|
EP2340050A2
(en)
*
|
2008-09-19 |
2011-07-06 |
Nektar Therapeutics |
Polymer conjugates of aod-like peptides
|
US20110171166A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of osteocalcin peptides
|
US20110171161A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of protegrin peptides
|
US20110171164A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of glp-2-like peptides
|
EP2340047A1
(en)
*
|
2008-09-19 |
2011-07-06 |
Nektar Therapeutics |
Polymer conjugates of kiss1 peptides
|
WO2010033222A2
(en)
*
|
2008-09-19 |
2010-03-25 |
Netkar Therapeutics |
Polymer conjugates of ziconotide peptides
|
US20110206633A1
(en)
*
|
2008-09-19 |
2011-08-25 |
Nektar Therapectics |
Polymer conjugates of cd-np peptides
|
WO2010033227A1
(en)
*
|
2008-09-19 |
2010-03-25 |
Nektar Therapeutics |
Polymer conjugates of thymosin alpha 1 peptides
|
US20110171165A1
(en)
*
|
2008-09-19 |
2011-07-14 |
Nektar Therapeutics |
Polymer conjugates of opioid growth factor peptides
|
EP2334333A1
(en)
*
|
2008-09-19 |
2011-06-22 |
Nektar Therapeutics |
Polymer conjugates of v681-like peptides
|
US20110165112A1
(en)
*
|
2008-09-19 |
2011-07-07 |
Nektar Therapeutics |
Polymer conjugates of c-peptides
|
CA2736939C
(en)
|
2008-09-23 |
2021-09-14 |
Nektar Therapeutics |
Means of achieving sustained-therapeutic sn-38 concentrations in a subject
|
AU2009307922A1
(en)
*
|
2008-10-21 |
2010-04-29 |
Enzon Pharmaceuticals, Inc. |
Treatment of neuroblastoma with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
|
JP5544357B2
(ja)
|
2009-05-15 |
2014-07-09 |
日本化薬株式会社 |
水酸基を有する生理活性物質の高分子結合体
|
MX2012013375A
(es)
|
2010-05-17 |
2013-04-11 |
Cebix Inc |
Peptido c pegilado.
|
EP2590680A1
(en)
|
2010-07-09 |
2013-05-15 |
Fresenius Kabi Deutschland GmbH |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
WO2012004009A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
WO2012004008A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
WO2012004006A1
(en)
|
2010-07-09 |
2012-01-12 |
Fresenius Kabi Deutschland Gmbh |
Conjugates comprising hydroxyalkyl starch and a cytotoxic agent and process for their preparation
|
CN102339813A
(zh)
|
2010-07-14 |
2012-02-01 |
中国科学院微电子研究所 |
半导体结构及其制造方法
|
WO2012067138A1
(ja)
|
2010-11-17 |
2012-05-24 |
日本化薬株式会社 |
新規なシチジン系代謝拮抗剤の高分子誘導体
|
WO2012088445A1
(en)
|
2010-12-22 |
2012-06-28 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
|
WO2012088422A1
(en)
|
2010-12-22 |
2012-06-28 |
Nektar Therapeutics |
Multi-arm polymeric prodrug conjugates of taxane-based compounds
|
ES2834992T3
(es)
*
|
2011-06-06 |
2021-06-21 |
Starpharma Pty Ltd |
Macromoléculas
|
PL2717917T3
(pl)
|
2011-07-05 |
2016-12-30 |
|
Koniugaty p97 - przeciwciało
|
US9346923B2
(en)
|
2011-09-11 |
2016-05-24 |
Nippon Kayaku Kabushiki Kaisha |
Method for manufacturing block copolymer
|
CN103083680B
(zh)
|
2011-11-07 |
2014-12-24 |
北京键凯科技有限公司 |
聚乙二醇-氨基酸寡肽-依诺替康药物结合物及其药物组合物
|
EP2797597B1
(en)
|
2011-12-28 |
2020-02-26 |
Global Blood Therapeutics, Inc. |
Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
|
PE20221914A1
(es)
|
2011-12-28 |
2022-12-23 |
Global Blood Therapeutics Inc |
Compuestos de benzaldehido sustituidos y metodos para su uso en incrementar la oxigenacion del tejido
|
JP6433424B2
(ja)
|
2012-07-31 |
2018-12-05 |
バイオアシス テクノロジーズ インコーポレイテッド |
脱リン酸化されたリソソーム蓄積症タンパク質およびその使用方法
|
EP2916835A4
(en)
|
2012-11-12 |
2016-07-27 |
Redwood Bioscience Inc |
COMPOUNDS AND METHOD FOR PRODUCING A CONJUGATE
|
CA2890906A1
(en)
|
2012-11-16 |
2014-05-22 |
The Regents Of The University Of California |
Pictet-spengler ligation for protein chemical modification
|
US9310374B2
(en)
|
2012-11-16 |
2016-04-12 |
Redwood Bioscience, Inc. |
Hydrazinyl-indole compounds and methods for producing a conjugate
|
BR112015022416A2
(pt)
|
2013-03-13 |
2017-10-24 |
Bioasis Technologies Inc |
fragmentos de p97 e seus usos
|
US9604999B2
(en)
|
2013-03-15 |
2017-03-28 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US9422279B2
(en)
|
2013-03-15 |
2016-08-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US10266551B2
(en)
|
2013-03-15 |
2019-04-23 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US9458139B2
(en)
|
2013-03-15 |
2016-10-04 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US10100043B2
(en)
|
2013-03-15 |
2018-10-16 |
Global Blood Therapeutics, Inc. |
Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
|
US20140274961A1
(en)
|
2013-03-15 |
2014-09-18 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
KR101971385B1
(ko)
|
2013-03-15 |
2019-04-22 |
글로벌 블러드 테라퓨틱스, 인크. |
헤모글로빈 조정을 위한 화합물 및 이의 용도
|
CN112500338A
(zh)
|
2013-03-15 |
2021-03-16 |
全球血液疗法股份有限公司 |
化合物及其用于调节血红蛋白的用途
|
AU2014237330A1
(en)
|
2013-03-15 |
2015-09-17 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
US9802900B2
(en)
|
2013-03-15 |
2017-10-31 |
Global Blood Therapeutics, Inc. |
Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
|
US8952171B2
(en)
|
2013-03-15 |
2015-02-10 |
Global Blood Therapeutics, Inc. |
Compounds and uses thereof for the modulation of hemoglobin
|
WO2015031673A2
(en)
|
2013-08-28 |
2015-03-05 |
Bioasis Technologies Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
EA201992707A1
(ru)
|
2013-11-18 |
2020-06-30 |
Глобал Блад Терапьютикс, Инк. |
Соединения и их применения для модуляции гемоглобина
|
WO2015081282A1
(en)
|
2013-11-27 |
2015-06-04 |
Redwood Bioscience, Inc. |
Hydrazinyl-pyrrolo compounds and methods for producing a conjugate
|
AU2015214182B2
(en)
|
2014-02-07 |
2020-04-30 |
Global Blood Therapeutics, Inc. |
Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
|
MA41841A
(fr)
|
2015-03-30 |
2018-02-06 |
Global Blood Therapeutics Inc |
Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
|
EP3371192B1
(en)
|
2015-10-27 |
2020-06-03 |
California Pacific Medical Center |
Podophyllotoxin derivatives and their use
|
US10087194B2
(en)
|
2015-10-27 |
2018-10-02 |
California Pacific Medical Center |
Podophyllotoxin derivatives and their use
|
MA43373A
(fr)
|
2015-12-04 |
2018-10-10 |
Global Blood Therapeutics Inc |
Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde
|
TWI663160B
(zh)
|
2016-05-12 |
2019-06-21 |
全球血液治療公司 |
用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
|
TW202332423A
(zh)
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
KR102459469B1
(ko)
|
2016-11-14 |
2022-10-26 |
항저우 디에이씨 바이오테크 씨오, 엘티디 |
결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
|
US11492493B2
(en)
|
2017-12-26 |
2022-11-08 |
Becton, Dickinson And Company |
Deep ultraviolet-excitable water-solvated polymeric dyes
|
EP3775052B1
(en)
|
2018-03-30 |
2024-06-05 |
Becton, Dickinson and Company |
Water-soluble polymeric dyes having pendant chromophores
|
CA3106568A1
(en)
|
2018-07-19 |
2020-01-23 |
Starpharma Pty Ltd |
Therapeutic dendrimer
|
CA3107332A1
(en)
|
2018-07-22 |
2020-01-30 |
Bioasis Technologies Inc. |
Treatment of lymphatic metastases
|
AU2019325261A1
(en)
*
|
2018-08-22 |
2021-03-18 |
Bacainn Biotherapeutics, Ltd. |
Cyclosporine compositions and methods of use
|
CN110862400A
(zh)
*
|
2018-08-27 |
2020-03-06 |
遵义医学院 |
喜树碱-羟基乙酸中间体的制备工艺
|
WO2020072377A1
(en)
|
2018-10-01 |
2020-04-09 |
Global Blood Therapeutics, Inc. |
Modulators of hemoglobin for the treatment of sickle cell disease
|
US20210355468A1
(en)
|
2020-05-18 |
2021-11-18 |
Bioasis Technologies, Inc. |
Compositions and methods for treating lewy body dementia
|
US20210393787A1
(en)
|
2020-06-17 |
2021-12-23 |
Bioasis Technologies, Inc. |
Compositions and methods for treating frontotemporal dementia
|
CA3128035A1
(en)
|
2020-08-13 |
2022-02-13 |
Bioasis Technologies, Inc. |
Combination therapies for delivery across the blood brain barrier
|
EP4155349A1
(en)
|
2021-09-24 |
2023-03-29 |
Becton, Dickinson and Company |
Water-soluble yellow green absorbing dyes
|
WO2024007016A2
(en)
|
2022-07-01 |
2024-01-04 |
Beckman Coulter, Inc. |
Novel fluorescent dyes and polymers from dihydrophenanthrene derivatives
|
WO2024044327A1
(en)
|
2022-08-26 |
2024-02-29 |
Beckman Coulter, Inc. |
Dhnt monomers and polymer dyes with modified photophysical properties
|