DK0922034T3 - Tetrahydroquinolinderivater som EAA-antagonister - Google Patents
Tetrahydroquinolinderivater som EAA-antagonisterInfo
- Publication number
- DK0922034T3 DK0922034T3 DK97943809T DK97943809T DK0922034T3 DK 0922034 T3 DK0922034 T3 DK 0922034T3 DK 97943809 T DK97943809 T DK 97943809T DK 97943809 T DK97943809 T DK 97943809T DK 0922034 T3 DK0922034 T3 DK 0922034T3
- Authority
- DK
- Denmark
- Prior art keywords
- tetrahydroquinoline derivatives
- eaa antagonists
- eaa
- antagonists
- tetrahydroquinoline
- Prior art date
Links
- 239000003194 amino acid receptor blocking agent Substances 0.000 title 1
- 125000000147 tetrahydroquinolinyl group Chemical class N1(CCCC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9617305.9A GB9617305D0 (en) | 1996-08-17 | 1996-08-17 | Heterocyclic compounds |
| PCT/EP1997/004440 WO1998007704A1 (en) | 1996-08-17 | 1997-08-14 | Tetrahydroquinoline derivatives as eaa antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0922034T3 true DK0922034T3 (da) | 2002-11-18 |
Family
ID=10798623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97943809T DK0922034T3 (da) | 1996-08-17 | 1997-08-14 | Tetrahydroquinolinderivater som EAA-antagonister |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6479488B1 (cs) |
| EP (1) | EP0922034B1 (cs) |
| JP (1) | JP4108129B2 (cs) |
| KR (1) | KR100552864B1 (cs) |
| CN (1) | CN1131214C (cs) |
| AP (1) | AP877A (cs) |
| AR (1) | AR008296A1 (cs) |
| AT (1) | ATE221052T1 (cs) |
| AU (1) | AU724473B2 (cs) |
| BR (1) | BR9711311B1 (cs) |
| CA (1) | CA2264118C (cs) |
| CO (1) | CO4900066A1 (cs) |
| CZ (1) | CZ296250B6 (cs) |
| DE (1) | DE69714265T2 (cs) |
| DK (1) | DK0922034T3 (cs) |
| EA (1) | EA001704B1 (cs) |
| ES (1) | ES2181030T3 (cs) |
| GB (1) | GB9617305D0 (cs) |
| HU (1) | HU225797B1 (cs) |
| ID (1) | ID18095A (cs) |
| IL (1) | IL128141A0 (cs) |
| IS (1) | IS4953A (cs) |
| MY (1) | MY116952A (cs) |
| NO (1) | NO312241B1 (cs) |
| NZ (1) | NZ333812A (cs) |
| PE (1) | PE107098A1 (cs) |
| PL (1) | PL194532B1 (cs) |
| PT (1) | PT922034E (cs) |
| SI (1) | SI0922034T1 (cs) |
| TR (1) | TR199900336T2 (cs) |
| TW (1) | TW449582B (cs) |
| WO (1) | WO1998007704A1 (cs) |
| YU (1) | YU6799A (cs) |
| ZA (1) | ZA977326B (cs) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706294D0 (en) * | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
| MY125037A (en) | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
| US6455734B1 (en) | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| GB9929037D0 (en) * | 1999-12-08 | 2000-02-02 | Glaxo Wellcome Spa | Heterocyclic derivatives |
| DE10132725A1 (de) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituierte γ-Lactonverbindungen |
| EP1461318B9 (en) * | 2001-12-28 | 2005-12-28 | Acadia Pharmaceuticals Inc. | Tetrahydroquinoline analogues as muscarinic agonists |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| AU2004206931A1 (en) * | 2003-01-23 | 2004-08-05 | Acadia Pharmaceuticals Inc. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20060233843A1 (en) * | 2003-02-19 | 2006-10-19 | Conn P J | Treatment of psychosis with a muscarinic m1 receptor ectopic activator |
| NZ547911A (en) * | 2003-12-22 | 2010-06-25 | Acadia Pharm Inc | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| CN1950346A (zh) * | 2004-04-01 | 2007-04-18 | 阿卡蒂亚药品公司 | N－去甲基氯氮平的晶形 |
| RU2451014C2 (ru) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Новое производное гетероциклиден ацетамида |
| KR101136183B1 (ko) | 2005-07-22 | 2012-04-17 | 모찌다 세이야쿠 가부시끼가이샤 | 신규 헤테로시클리덴 아세트아미드 유도체 |
| EP1966229B1 (en) | 2005-09-12 | 2015-10-21 | Abela Pharmaceuticals, Inc. | Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same |
| EP2324838A1 (en) * | 2005-09-12 | 2011-05-25 | Abela Pharmaceuticals, Inc. | Compositions Comprising Dimethyl Sulfoxide (DMSO) |
| US8480797B2 (en) | 2005-09-12 | 2013-07-09 | Abela Pharmaceuticals, Inc. | Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors |
| WO2007033180A1 (en) | 2005-09-12 | 2007-03-22 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (dmso) and related compounds |
| US20070105836A1 (en) * | 2005-10-31 | 2007-05-10 | Lars Pettersson | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| BRPI0921494A2 (pt) | 2008-11-03 | 2018-10-30 | Prad Reasearch And Development Ltd | método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração. |
| CA2779111C (en) | 2009-10-30 | 2019-08-13 | Abela Pharmaceuticals, Inc. | Dimethyl sulfoxide (dmso) and methylsulfonylmethane (msm) formulations to treat osteoarthritis |
| CA2850707C (en) | 2011-10-03 | 2023-03-21 | The University Of Utah Research Foundation | Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE147732T1 (de) * | 1989-03-08 | 1997-02-15 | Merck Sharp & Dohme | Tetrahydroquinolin-derivate, verwendbar bei neurodegenerativen krankheiten |
| JP4108123B2 (ja) * | 1995-09-29 | 2008-06-25 | グラクソスミスクライン・ソシエタ・ペル・アチオニ | Ｎｍｄａアンタゴニストとしてのテトラヒドロキノリン |
-
1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
-
1997
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 SI SI9730404T patent/SI0922034T1/xx unknown
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/en not_active Ceased
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active Expired - Fee Related
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 CA CA002264118A patent/CA2264118C/en not_active Expired - Fee Related
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 EP EP97943809A patent/EP0922034B1/en not_active Expired - Lifetime
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
-
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation
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