ZA977326B - Tetrahydroquinoline derivatives - Google Patents
Tetrahydroquinoline derivativesInfo
- Publication number
- ZA977326B ZA977326B ZA977326A ZA977326A ZA977326B ZA 977326 B ZA977326 B ZA 977326B ZA 977326 A ZA977326 A ZA 977326A ZA 977326 A ZA977326 A ZA 977326A ZA 977326 B ZA977326 B ZA 977326B
- Authority
- ZA
- South Africa
- Prior art keywords
- tetrahydroquinoline derivatives
- tetrahydroquinoline
- derivatives
- Prior art date
Links
- 125000000147 tetrahydroquinolinyl group Chemical class N1(CCCC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9617305.9A GB9617305D0 (en) | 1996-08-17 | 1996-08-17 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA977326B true ZA977326B (en) | 1999-02-15 |
Family
ID=10798623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA977326A ZA977326B (en) | 1996-08-17 | 1997-08-14 | Tetrahydroquinoline derivatives |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6479488B1 (cs) |
| EP (1) | EP0922034B1 (cs) |
| JP (1) | JP4108129B2 (cs) |
| KR (1) | KR100552864B1 (cs) |
| CN (1) | CN1131214C (cs) |
| AP (1) | AP877A (cs) |
| AR (1) | AR008296A1 (cs) |
| AT (1) | ATE221052T1 (cs) |
| AU (1) | AU724473B2 (cs) |
| BR (1) | BR9711311B1 (cs) |
| CA (1) | CA2264118C (cs) |
| CO (1) | CO4900066A1 (cs) |
| CZ (1) | CZ296250B6 (cs) |
| DE (1) | DE69714265T2 (cs) |
| DK (1) | DK0922034T3 (cs) |
| EA (1) | EA001704B1 (cs) |
| ES (1) | ES2181030T3 (cs) |
| GB (1) | GB9617305D0 (cs) |
| HU (1) | HU225797B1 (cs) |
| ID (1) | ID18095A (cs) |
| IL (1) | IL128141A0 (cs) |
| IS (1) | IS4953A (cs) |
| MY (1) | MY116952A (cs) |
| NO (1) | NO312241B1 (cs) |
| NZ (1) | NZ333812A (cs) |
| PE (1) | PE107098A1 (cs) |
| PL (1) | PL194532B1 (cs) |
| PT (1) | PT922034E (cs) |
| SI (1) | SI0922034T1 (cs) |
| TR (1) | TR199900336T2 (cs) |
| TW (1) | TW449582B (cs) |
| WO (1) | WO1998007704A1 (cs) |
| YU (1) | YU6799A (cs) |
| ZA (1) | ZA977326B (cs) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9706294D0 (en) * | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
| MY125037A (en) * | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
| US6455734B1 (en) | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| GB9929037D0 (en) * | 1999-12-08 | 2000-02-02 | Glaxo Wellcome Spa | Heterocyclic derivatives |
| DE10132725A1 (de) | 2001-07-05 | 2006-08-03 | Grünenthal GmbH | Substituierte γ-Lactonverbindungen |
| IL162616A0 (en) * | 2001-12-28 | 2005-11-20 | Acadia Pharm Inc | Tetrahydroquinoline analogues as muscarinic agonists |
| US20050250767A1 (en) * | 2003-01-23 | 2005-11-10 | Weiner David M | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| AU2004206931A1 (en) * | 2003-01-23 | 2004-08-05 | Acadia Pharmaceuticals Inc. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20050085463A1 (en) * | 2003-01-23 | 2005-04-21 | Weiner David M. | Use of N-desmethylclozapine to treat human neuropsychiatric disease |
| US20060233843A1 (en) * | 2003-02-19 | 2006-10-19 | Conn P J | Treatment of psychosis with a muscarinic m1 receptor ectopic activator |
| JP2007534656A (ja) * | 2003-12-22 | 2007-11-29 | アカディア ファーマシューティカルズ,インコーポレーテッド | ムスカリンアゴニストとしてのアミノ置換ジアリール[a,d]シクロヘプテン類似体および精神神経疾患の治療方法 |
| KR20070007888A (ko) * | 2004-04-01 | 2007-01-16 | 아카디아 파마슈티칼스 인코포레이티드 | 결정질 n-데스메틸클로자핀 |
| US7910751B2 (en) | 2005-07-22 | 2011-03-22 | Mochida Pharmaceutical Co., Ltd. | Heterocyclidene acetamide derivative |
| RU2451014C2 (ru) * | 2005-07-22 | 2012-05-20 | Мотида Фармасьютикал Ко., Лтд. | Новое производное гетероциклиден ацетамида |
| WO2007033082A2 (en) * | 2005-09-12 | 2007-03-22 | Abela Pharmaceuticals, Inc. | Compositions comprising dimethyl sulfoxide (dmso) |
| US8480797B2 (en) | 2005-09-12 | 2013-07-09 | Abela Pharmaceuticals, Inc. | Activated carbon systems for facilitating use of dimethyl sulfoxide (DMSO) by removal of same, related compounds, or associated odors |
| US8435224B2 (en) | 2005-09-12 | 2013-05-07 | Abela Pharmaceuticals, Inc. | Materials for facilitating administration of dimethyl sulfoxide (DMSO) and related compounds |
| EP1966229B1 (en) | 2005-09-12 | 2015-10-21 | Abela Pharmaceuticals, Inc. | Systems for removing dimethyl sulfoxide (dmso) or related compounds, or odors associated with same |
| WO2007053618A1 (en) * | 2005-10-31 | 2007-05-10 | Acadia Pharmaceuticals Inc. | Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| BRPI0921494A2 (pt) | 2008-11-03 | 2018-10-30 | Prad Reasearch And Development Ltd | método de planejamento de uma operação de amostragem para uma formação subterrãnea, método de contolar uma operação de amostragem de formação subterrânea, método de controlar uma operação de perfuração para uma formação subterrãnea, e método de realizar uma amostragem durante a operação de perfuração. |
| WO2011053874A1 (en) | 2009-10-30 | 2011-05-05 | Tandem Abela Development Group Llc | Dimethyl sulfoxide (dmso) and methylsulfonylmethane (msm) formulations to treat osteoarthritis |
| EP3718547A1 (en) | 2011-10-03 | 2020-10-07 | The University of Utah Research Foundation | Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0386839B1 (en) * | 1989-03-08 | 1997-01-15 | Merck Sharp & Dohme Ltd. | Tetrahydroquinoline derivatives useful for neurodegenerative disorders |
| WO1997012870A1 (en) | 1995-09-29 | 1997-04-10 | Glaxo Wellcome S.P.A. | Tetrahydroquinolines as nmda antagonists |
-
1996
- 1996-08-17 GB GBGB9617305.9A patent/GB9617305D0/en active Pending
-
1997
- 1997-08-14 EA EA199900121A patent/EA001704B1/ru not_active IP Right Cessation
- 1997-08-14 MY MYPI97003742A patent/MY116952A/en unknown
- 1997-08-14 AP APAP/P/1999/001459A patent/AP877A/en active
- 1997-08-14 EP EP97943809A patent/EP0922034B1/en not_active Expired - Lifetime
- 1997-08-14 ID IDP972834A patent/ID18095A/id unknown
- 1997-08-14 NZ NZ333812A patent/NZ333812A/xx active Application Revival
- 1997-08-14 SI SI9730404T patent/SI0922034T1/xx unknown
- 1997-08-14 KR KR1019997001280A patent/KR100552864B1/ko not_active Expired - Fee Related
- 1997-08-14 DE DE69714265T patent/DE69714265T2/de not_active Expired - Lifetime
- 1997-08-14 ES ES97943809T patent/ES2181030T3/es not_active Expired - Lifetime
- 1997-08-14 CZ CZ0052999A patent/CZ296250B6/cs not_active IP Right Cessation
- 1997-08-14 AT AT97943809T patent/ATE221052T1/de not_active IP Right Cessation
- 1997-08-14 US US09/147,568 patent/US6479488B1/en not_active Expired - Fee Related
- 1997-08-14 YU YU6799A patent/YU6799A/sh unknown
- 1997-08-14 TR TR1999/00336T patent/TR199900336T2/xx unknown
- 1997-08-14 ZA ZA977326A patent/ZA977326B/xx unknown
- 1997-08-14 BR BRPI9711311-5A patent/BR9711311B1/pt not_active IP Right Cessation
- 1997-08-14 PL PL97331562A patent/PL194532B1/pl not_active IP Right Cessation
- 1997-08-14 PE PE1997000718A patent/PE107098A1/es not_active Application Discontinuation
- 1997-08-14 AU AU45518/97A patent/AU724473B2/en not_active Ceased
- 1997-08-14 JP JP51037298A patent/JP4108129B2/ja not_active Expired - Fee Related
- 1997-08-14 CN CN97197233A patent/CN1131214C/zh not_active Expired - Fee Related
- 1997-08-14 DK DK97943809T patent/DK0922034T3/da active
- 1997-08-14 HU HU9903108A patent/HU225797B1/hu not_active IP Right Cessation
- 1997-08-14 WO PCT/EP1997/004440 patent/WO1998007704A1/en active IP Right Grant
- 1997-08-14 CO CO97046782A patent/CO4900066A1/es unknown
- 1997-08-14 IL IL12814197A patent/IL128141A0/xx not_active IP Right Cessation
- 1997-08-14 CA CA002264118A patent/CA2264118C/en not_active Expired - Fee Related
- 1997-08-14 PT PT97943809T patent/PT922034E/pt unknown
- 1997-08-14 AR ARP970103703A patent/AR008296A1/es active IP Right Grant
- 1997-08-30 TW TW086112442A patent/TW449582B/zh not_active IP Right Cessation
-
1999
- 1999-01-22 IS IS4953A patent/IS4953A/is unknown
- 1999-02-16 NO NO19990723A patent/NO312241B1/no not_active IP Right Cessation
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