DK0920491T3 - Immortaliserede cellelinier til virusvækst - Google Patents

Immortaliserede cellelinier til virusvækst

Info

Publication number
DK0920491T3
DK0920491T3 DK97938334T DK97938334T DK0920491T3 DK 0920491 T3 DK0920491 T3 DK 0920491T3 DK 97938334 T DK97938334 T DK 97938334T DK 97938334 T DK97938334 T DK 97938334T DK 0920491 T3 DK0920491 T3 DK 0920491T3
Authority
DK
Denmark
Prior art keywords
cell lines
immortalized cell
virus growth
virus
growth
Prior art date
Application number
DK97938334T
Other languages
English (en)
Inventor
Douglas N Foster
Linda K Foster
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Application granted granted Critical
Publication of DK0920491T3 publication Critical patent/DK0920491T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • C12N15/867Retroviral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16651Methods of production or purification of viral material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK97938334T 1996-08-13 1997-08-13 Immortaliserede cellelinier til virusvækst DK0920491T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/696,200 US5672485A (en) 1996-08-13 1996-08-13 Immortalized cell lines for virus growth
PCT/US1997/014384 WO1998006824A1 (en) 1996-08-13 1997-08-13 Immortalized cell lines for virus growth

Publications (1)

Publication Number Publication Date
DK0920491T3 true DK0920491T3 (da) 2007-09-17

Family

ID=24796108

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97938334T DK0920491T3 (da) 1996-08-13 1997-08-13 Immortaliserede cellelinier til virusvækst

Country Status (29)

Country Link
US (4) US5672485A (da)
EP (1) EP0920491B1 (da)
JP (3) JP3754088B2 (da)
KR (1) KR100375871B1 (da)
CN (1) CN1228119B (da)
AR (1) AR008294A1 (da)
AT (1) ATE362524T1 (da)
AU (1) AU726820B2 (da)
BR (1) BR9711067A (da)
CA (1) CA2263725C (da)
CO (1) CO4700552A1 (da)
DE (1) DE69737735T2 (da)
DK (1) DK0920491T3 (da)
DZ (1) DZ2291A1 (da)
ES (1) ES2285738T3 (da)
GT (1) GT199700091A (da)
HK (1) HK1022496A1 (da)
HN (1) HN1997000124A (da)
HU (1) HU226658B1 (da)
IL (4) IL128511A (da)
MA (1) MA24303A1 (da)
MY (1) MY125594A (da)
NZ (1) NZ334147A (da)
PE (1) PE108198A1 (da)
PT (1) PT920491E (da)
SV (1) SV1997000071A (da)
UY (1) UY24668A1 (da)
WO (1) WO1998006824A1 (da)
ZA (1) ZA977216B (da)

Families Citing this family (60)

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US5672485A (en) * 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
US6821741B1 (en) * 2001-04-27 2004-11-23 University Hospitals Of Cleveland Cells for detection of enteroviruses
US6552172B2 (en) 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
US20040023358A1 (en) * 2001-12-21 2004-02-05 Wyeth Avian embryo particulate biomass for the production of virus antigens
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
US20090217404A1 (en) * 2002-09-27 2009-08-27 Lowe Scott W Cell-based RNA interference and related methods and compositions
WO2004031450A1 (ja) * 2002-09-30 2004-04-15 Honda Giken Kogyo Kabushiki Kaisha 水素活性化装置
US20040170646A1 (en) * 2002-12-13 2004-09-02 Aventis Pasteur, Inc. Production of ALVAC on avian embryonic stem cells
US20090186839A1 (en) * 2003-02-17 2009-07-23 Cold Spring Harbor Laboratory Model for studying the role of genes in chemoresistance
WO2004074445A2 (en) * 2003-02-17 2004-09-02 Cold Spring Harbor Laboratory Model for studying the role of genes in tumor resistance to chemotherapy
US20050273873A1 (en) * 2003-03-07 2005-12-08 Avigenics, Inc. Genomic modification
US20040255345A1 (en) * 2003-03-07 2004-12-16 Rapp Jeffrey C. Production of transgenic avians
EP1608219A4 (en) * 2003-03-07 2007-03-14 Avigenics Inc AVIAN TRANSGENESIS MEDIATED BY INTEGRASE
US20050198700A1 (en) * 2003-03-07 2005-09-08 Avigenics, Inc. Genomic modification
US20050034186A1 (en) * 2003-03-07 2005-02-10 Harvey Alex J. Site specific nucleic acid integration
ATE467678T1 (de) 2003-07-22 2010-05-15 Vivalis Produktion von poxviren mit adhärenten oder nicht adhärenten vogelzellinien
WO2005028634A2 (en) * 2003-09-18 2005-03-31 Emory University Improved mva vaccines
EP1528101A1 (en) 2003-11-03 2005-05-04 ProBioGen AG Immortalized avian cell lines for virus production
US20060123504A1 (en) * 2004-12-07 2006-06-08 Avigenics, Inc. Methods of producing polyclonal antibodies
US20060174364A1 (en) * 2004-03-01 2006-08-03 Avigenics, Inc. Artificial chromosomes and transchromosomic avians
WO2006042214A1 (en) * 2004-10-08 2006-04-20 Avigenics, Inc. Modified integrase and methods of use
US8137907B2 (en) * 2005-01-03 2012-03-20 Cold Spring Harbor Laboratory Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
EP1896587A2 (en) 2005-05-31 2008-03-12 Cold Spring Harbor Laboratory METHODS FOR PRODUCING MICRORNAs
US7524626B2 (en) * 2005-10-05 2009-04-28 Synageva Biopharma Corp. Rapid production of high titer virus
RU2489486C2 (ru) 2006-06-20 2013-08-10 Трансжене С.А. Процесс получения поксвирусов и композиции поксвирусов
CN100443588C (zh) * 2006-12-11 2008-12-17 中国农业科学院北京畜牧兽医研究所 静宁鸡胚成纤维细胞系及其培养方法
US8213704B2 (en) * 2007-05-09 2012-07-03 Kla-Tencor Corp. Methods and systems for detecting defects in a reticle design pattern
EP2014279A1 (en) * 2007-06-22 2009-01-14 Pevion Biotech AG Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof
ES2618490T3 (es) 2007-07-03 2017-06-21 Transgene Sa Estirpes celulares aviares inmortalizadas
US8357531B2 (en) 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
US8901288B2 (en) * 2007-10-26 2014-12-02 Cold Spring Harbor Laboratory High throughput methods for functionally determining RNA interference efficiency
EP2257622B1 (en) 2008-02-25 2017-03-22 Nanotherapeutics, Inc. Method for producing continuous cell lines
RU2560976C2 (ru) 2009-05-12 2015-08-20 Трансген Са Способ продуцирования и очистки ортопоксвируса
WO2010144797A2 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Influenza vaccines with enhanced immunogenicity and uses thereof
AU2011281982B2 (en) 2010-07-20 2015-12-17 Bavarian Nordic A/S Method for harvesting expression products
FR3008992A1 (fr) * 2013-07-25 2015-01-30 Agronomique Inst Nat Rech Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires
MX2017007178A (es) 2014-12-01 2017-08-28 Transgene Sa Formulaciones liquidas estables de virus de vacuna.
BR112017011582A2 (pt) 2014-12-04 2018-02-27 Intervet Int Bv fibroblasto de embrião de galinha imortalizado, cultura de célula, métodos para preparação de um cef importalizado, para a replicação de um vetor viral aviário e para a preparação de uma vacina, e, vacina.
KR101768581B1 (ko) * 2015-08-13 2017-08-17 전북대학교 산학협력단 자발적 불멸화된 체세포의 단일 세포로부터 리프로그래밍 세포주의 제조방법
EP3387113A1 (en) * 2015-12-11 2018-10-17 Intervet International B.V. Immortalised chicken embryonic epithelial kidney cells
EP3452081A1 (en) 2016-05-04 2019-03-13 Transgene SA Combination therapy with cpg tlr9 ligand
EP3522920A2 (en) 2016-10-10 2019-08-14 Transgene SA Immunotherapeutic product and mdsc modulator combination therapy
WO2018093903A1 (en) 2016-11-17 2018-05-24 Regents Of The University Of Minnesota Immortalized cell lines and methods of use
CA3061678A1 (en) 2017-05-15 2018-11-22 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
CA3062549A1 (en) 2017-05-15 2018-11-22 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
JP7334124B2 (ja) 2017-06-21 2023-08-28 トランジェーヌ 個別化ワクチン
CN107858323B (zh) * 2017-11-08 2020-10-09 广东省生物资源应用研究所 一种红耳龟胚胎成纤维细胞系及其构建方法
CN109234239B (zh) * 2018-07-13 2021-09-14 广东永顺生物制药股份有限公司 一种鸭瘟病毒的培养方法
WO2020049151A1 (en) 2018-09-06 2020-03-12 Bavarian Nordic A/S Storage improved poxvirus compositions
BR112022010825A2 (pt) 2019-12-20 2022-08-23 Intervet Int Bv Vacina de vetor hvt multivalente
BR112022017438A2 (pt) 2020-03-12 2022-10-18 Bavarian Nordic As Composições que melhoram a estabilidade do poxvírus
AU2021309007A1 (en) 2020-07-13 2023-02-16 Transgene Treatment of immune depression
US20240024456A1 (en) 2020-09-07 2024-01-25 Intervet Inc. Ha stem vaccine for ha antibody-positive targets
CN116648259A (zh) 2020-12-24 2023-08-25 英特维特国际股份有限公司 多价hvt载体疫苗
EP4370150A1 (en) 2021-07-13 2024-05-22 Intervet International B.V. Overcoming antibody-interference in avians
WO2023213764A1 (en) 2022-05-02 2023-11-09 Transgene Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
WO2023213763A1 (en) 2022-05-02 2023-11-09 Transgene Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
WO2023213946A1 (en) 2022-05-05 2023-11-09 Intervet International B.V. New multivalent hvt vector vaccine

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JP3058438B2 (ja) * 1990-10-19 2000-07-04 財団法人化学及血清療法研究所 ヒト肝臓組織特異的ウイルスの感染可能な霊長類の不死化肝細胞およびその調製方法
US5672485A (en) * 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth

Also Published As

Publication number Publication date
IL158303A0 (en) 2004-05-12
JP2005118053A (ja) 2005-05-12
SV1997000071A (es) 2000-07-06
HUP0000188A3 (en) 2005-11-28
AU4069197A (en) 1998-03-06
KR20000029968A (ko) 2000-05-25
GT199700091A (es) 1997-08-12
IL128511A (en) 2004-06-01
EP0920491A1 (en) 1999-06-09
IL158302A0 (en) 2004-05-12
WO1998006824A1 (en) 1998-02-19
AR008294A1 (es) 1999-12-29
CN1228119A (zh) 1999-09-08
HU226658B1 (en) 2009-06-29
CA2263725A1 (en) 1998-02-19
PE108198A1 (es) 1999-01-21
HN1997000124A (es) 1999-03-19
EP0920491B1 (en) 2007-05-16
JP3754088B2 (ja) 2006-03-08
ES2285738T3 (es) 2007-11-16
US5879924A (en) 1999-03-09
CA2263725C (en) 2002-10-15
NZ334147A (en) 2000-08-25
KR100375871B1 (ko) 2003-03-10
MY125594A (en) 2006-08-30
IL158301A0 (en) 2004-05-12
UY24668A1 (es) 1998-02-02
CO4700552A1 (es) 1998-12-29
HK1022496A1 (en) 2000-08-11
HUP0000188A2 (hu) 2000-06-28
AU726820B2 (en) 2000-11-23
US5985642A (en) 1999-11-16
JP2000516095A (ja) 2000-12-05
IL128511A0 (en) 2000-01-31
CN1228119B (zh) 2012-04-04
BR9711067A (pt) 1999-08-17
ATE362524T1 (de) 2007-06-15
DE69737735D1 (de) 2007-06-28
US5672485A (en) 1997-09-30
JP2006320328A (ja) 2006-11-30
PT920491E (pt) 2007-07-27
MA24303A1 (fr) 1998-04-01
ZA977216B (en) 1998-02-19
DE69737735T2 (de) 2008-01-31
US6207415B1 (en) 2001-03-27
DZ2291A1 (fr) 2002-12-25

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