HUP0000188A2 - Immortalizált sejtvonalak vírusszaporításra - Google Patents

Immortalizált sejtvonalak vírusszaporításra

Info

Publication number
HUP0000188A2
HUP0000188A2 HU0000188A HUP0000188A HUP0000188A2 HU P0000188 A2 HUP0000188 A2 HU P0000188A2 HU 0000188 A HU0000188 A HU 0000188A HU P0000188 A HUP0000188 A HU P0000188A HU P0000188 A2 HUP0000188 A2 HU P0000188A2
Authority
HU
Hungary
Prior art keywords
immortalized cell
cell lines
virus growth
subject
cell line
Prior art date
Application number
HU0000188A
Other languages
English (en)
Inventor
Douglas N. Foster
Linda K. Foster
Original Assignee
Regents Of The University Of Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regents Of The University Of Minnesota filed Critical Regents Of The University Of Minnesota
Publication of HUP0000188A2 publication Critical patent/HUP0000188A2/hu
Publication of HUP0000188A3 publication Critical patent/HUP0000188A3/hu
Publication of HU226658B1 publication Critical patent/HU226658B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/867—Retroviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16651—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12051—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A találmány tárgyát spőntán módőn immőrtalizált sejtvőnal képezi,amely elsődleges csirkeembrió-fibrőblasztból származik, és amelysejtvőnal tenyészetben mintegy 0.6-tól mintegy 1.2pőpűlációdűplázódás/ nap sebességgel képes növekedni. A találmánytárgyát képezi tővábbá eljárás immőrtalizált sejtvőnal előállításáracsirkeembrió-fibrőblasztból. A találmány szerinti megőldás avírűsszapőrítás területén alkalmazható. ŕ
HU0000188A 1996-08-13 1997-08-13 Immortalized cell lines for virus growth HU226658B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/696,200 US5672485A (en) 1996-08-13 1996-08-13 Immortalized cell lines for virus growth
PCT/US1997/014384 WO1998006824A1 (en) 1996-08-13 1997-08-13 Immortalized cell lines for virus growth

Publications (3)

Publication Number Publication Date
HUP0000188A2 true HUP0000188A2 (hu) 2000-06-28
HUP0000188A3 HUP0000188A3 (en) 2005-11-28
HU226658B1 HU226658B1 (en) 2009-06-29

Family

ID=24796108

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000188A HU226658B1 (en) 1996-08-13 1997-08-13 Immortalized cell lines for virus growth

Country Status (29)

Country Link
US (4) US5672485A (hu)
EP (1) EP0920491B1 (hu)
JP (3) JP3754088B2 (hu)
KR (1) KR100375871B1 (hu)
CN (1) CN1228119B (hu)
AR (1) AR008294A1 (hu)
AT (1) ATE362524T1 (hu)
AU (1) AU726820B2 (hu)
BR (1) BR9711067A (hu)
CA (1) CA2263725C (hu)
CO (1) CO4700552A1 (hu)
DE (1) DE69737735T2 (hu)
DK (1) DK0920491T3 (hu)
DZ (1) DZ2291A1 (hu)
ES (1) ES2285738T3 (hu)
GT (1) GT199700091A (hu)
HK (1) HK1022496A1 (hu)
HN (1) HN1997000124A (hu)
HU (1) HU226658B1 (hu)
IL (4) IL158302A0 (hu)
MA (1) MA24303A1 (hu)
MY (1) MY125594A (hu)
NZ (1) NZ334147A (hu)
PE (1) PE108198A1 (hu)
PT (1) PT920491E (hu)
SV (1) SV1997000071A (hu)
UY (1) UY24668A1 (hu)
WO (1) WO1998006824A1 (hu)
ZA (1) ZA977216B (hu)

Families Citing this family (60)

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US5672485A (en) * 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
US6821741B1 (en) * 2001-04-27 2004-11-23 University Hospitals Of Cleveland Cells for detection of enteroviruses
US6552172B2 (en) 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
US20040023358A1 (en) * 2001-12-21 2004-02-05 Wyeth Avian embryo particulate biomass for the production of virus antigens
FR2836924B1 (fr) 2002-03-08 2005-01-14 Vivalis Lignees de cellules aviaires utiles pour la production de substances d'interet
US20090217404A1 (en) * 2002-09-27 2009-08-27 Lowe Scott W Cell-based RNA interference and related methods and compositions
US7410557B2 (en) * 2002-09-30 2008-08-12 Honda Motor Co., Ltd. Hydrogen activating apparatus
CN1726276A (zh) * 2002-12-13 2006-01-25 艾文蒂斯·帕斯图尔公司 Alvac在禽胚胎干细胞上的生产
US20090186839A1 (en) * 2003-02-17 2009-07-23 Cold Spring Harbor Laboratory Model for studying the role of genes in chemoresistance
WO2004074445A2 (en) * 2003-02-17 2004-09-02 Cold Spring Harbor Laboratory Model for studying the role of genes in tumor resistance to chemotherapy
US20050273873A1 (en) * 2003-03-07 2005-12-08 Avigenics, Inc. Genomic modification
US20050034186A1 (en) * 2003-03-07 2005-02-10 Harvey Alex J. Site specific nucleic acid integration
US20050198700A1 (en) * 2003-03-07 2005-09-08 Avigenics, Inc. Genomic modification
EP1608219A4 (en) * 2003-03-07 2007-03-14 Avigenics Inc AVIAN TRANSGENESIS MEDIATED BY INTEGRASE
US20040255345A1 (en) * 2003-03-07 2004-12-16 Rapp Jeffrey C. Production of transgenic avians
DK1646715T3 (da) 2003-07-22 2010-08-16 Vivalis Fremstilling af poxvirum med adhærente eller ikke-adhærente fuglecellelinjer
US20070275010A1 (en) * 2003-09-18 2007-11-29 Mark Feinberg Mva Vaccines
EP1528101A1 (en) 2003-11-03 2005-05-04 ProBioGen AG Immortalized avian cell lines for virus production
US20060123504A1 (en) * 2004-12-07 2006-06-08 Avigenics, Inc. Methods of producing polyclonal antibodies
US20060174364A1 (en) * 2004-03-01 2006-08-03 Avigenics, Inc. Artificial chromosomes and transchromosomic avians
WO2006042214A1 (en) * 2004-10-08 2006-04-20 Avigenics, Inc. Modified integrase and methods of use
US8137907B2 (en) * 2005-01-03 2012-03-20 Cold Spring Harbor Laboratory Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof
FR2884255B1 (fr) 2005-04-11 2010-11-05 Vivalis Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe
US20070044164A1 (en) * 2005-05-31 2007-02-22 Cold Spring Harbor Laboratory Methods for producing microRNAs
TR201909425T4 (tr) 2005-10-05 2019-07-22 Alexion Pharma Inc Yüksek ti̇treli̇ vi̇rüsün hizli üreti̇mi̇
JP5456464B2 (ja) 2006-06-20 2014-03-26 トランジェーヌ、ソシエテ、アノニム ポックスウイルスおよびポックスウイルス組成物の製造方法
CN100443588C (zh) * 2006-12-11 2008-12-17 中国农业科学院北京畜牧兽医研究所 静宁鸡胚成纤维细胞系及其培养方法
US8213704B2 (en) * 2007-05-09 2012-07-03 Kla-Tencor Corp. Methods and systems for detecting defects in a reticle design pattern
EP2014279A1 (en) * 2007-06-22 2009-01-14 Pevion Biotech AG Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof
KR101528379B1 (ko) * 2007-07-03 2015-06-16 트랜스진 에스.에이. 불멸화된 조류 세포주들
US8357531B2 (en) * 2007-07-03 2013-01-22 Transgene S.A. Immortalized avian cell lines
US8901288B2 (en) * 2007-10-26 2014-12-02 Cold Spring Harbor Laboratory High throughput methods for functionally determining RNA interference efficiency
BRPI0907539A2 (pt) 2008-02-25 2015-07-28 Baxter Int Método para produzir linhagens de células contínuas, e, linhagens de células
US8609392B2 (en) * 2009-05-12 2013-12-17 Transgene S.A. Method for orthopoxvirus production and purification
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AU2011281982B2 (en) 2010-07-20 2015-12-17 Bavarian Nordic A/S Method for harvesting expression products
FR3008992A1 (fr) 2013-07-25 2015-01-30 Agronomique Inst Nat Rech Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires
RU2704485C2 (ru) 2014-12-01 2019-10-29 Трансген Са Стабильные жидкие препараты вируса осповакцины
JP6546659B2 (ja) 2014-12-04 2019-07-17 インターベット インターナショナル ベー． フェー． 不死化ニワトリ胚線維芽細胞
KR101768581B1 (ko) * 2015-08-13 2017-08-17 전북대학교 산학협력단 자발적 불멸화된 체세포의 단일 세포로부터 리프로그래밍 세포주의 제조방법
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WO2018069316A2 (en) 2016-10-10 2018-04-19 Transgene Sa Immunotherapeutic product and mdsc modulator combination therapy
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JP7406377B2 (ja) 2017-05-15 2023-12-27 ヤンセン ファッシンズ アンド プリベンション ベーフェー 安定なウイルス含有組成物
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CN109234239B (zh) * 2018-07-13 2021-09-14 广东永顺生物制药股份有限公司 一种鸭瘟病毒的培养方法
CA3111273C (en) 2018-09-06 2024-03-26 Bavarian Nordic A/S Storage improved poxvirus compositions
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CN115243717A (zh) 2020-03-12 2022-10-25 巴法里安诺迪克有限公司 改善痘病毒稳定性的组合物
CA3189238A1 (en) 2020-07-13 2022-01-20 Transgene Treatment of immune depression
WO2022049276A1 (en) 2020-09-07 2022-03-10 Intervet International B.V. Ha stem vaccine for ha antibody-positive targets
JP2024501943A (ja) 2020-12-24 2024-01-17 インターベット インターナショナル ベー． フェー． 多価ｈｖｔベクターワクチン
EP4370150A1 (en) 2021-07-13 2024-05-22 Intervet International B.V. Overcoming antibody-interference in avians
WO2023213763A1 (en) 2022-05-02 2023-11-09 Transgene Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
WO2023213764A1 (en) 2022-05-02 2023-11-09 Transgene Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
WO2023213946A1 (en) 2022-05-05 2023-11-09 Intervet International B.V. New multivalent hvt vector vaccine

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JP3058438B2 (ja) * 1990-10-19 2000-07-04 財団法人化学及血清療法研究所 ヒト肝臓組織特異的ウイルスの感染可能な霊長類の不死化肝細胞およびその調製方法
US5672485A (en) * 1996-08-13 1997-09-30 Regents Of The University Of Minnesota Immortalized cell lines for virus growth

Also Published As

Publication number Publication date
IL128511A0 (en) 2000-01-31
IL158303A0 (en) 2004-05-12
CO4700552A1 (es) 1998-12-29
MY125594A (en) 2006-08-30
NZ334147A (en) 2000-08-25
MA24303A1 (fr) 1998-04-01
IL158302A0 (en) 2004-05-12
HU226658B1 (en) 2009-06-29
UY24668A1 (es) 1998-02-02
JP2006320328A (ja) 2006-11-30
US5672485A (en) 1997-09-30
US5985642A (en) 1999-11-16
KR20000029968A (ko) 2000-05-25
BR9711067A (pt) 1999-08-17
JP3754088B2 (ja) 2006-03-08
HK1022496A1 (en) 2000-08-11
PE108198A1 (es) 1999-01-21
CN1228119B (zh) 2012-04-04
HUP0000188A3 (en) 2005-11-28
US6207415B1 (en) 2001-03-27
IL128511A (en) 2004-06-01
JP2005118053A (ja) 2005-05-12
WO1998006824A1 (en) 1998-02-19
JP2000516095A (ja) 2000-12-05
ATE362524T1 (de) 2007-06-15
DZ2291A1 (fr) 2002-12-25
PT920491E (pt) 2007-07-27
AR008294A1 (es) 1999-12-29
HN1997000124A (es) 1999-03-19
CA2263725C (en) 2002-10-15
EP0920491A1 (en) 1999-06-09
DK0920491T3 (da) 2007-09-17
ZA977216B (en) 1998-02-19
AU4069197A (en) 1998-03-06
CA2263725A1 (en) 1998-02-19
SV1997000071A (es) 2000-07-06
DE69737735D1 (de) 2007-06-28
GT199700091A (es) 1997-08-12
KR100375871B1 (ko) 2003-03-10
AU726820B2 (en) 2000-11-23
ES2285738T3 (es) 2007-11-16
EP0920491B1 (en) 2007-05-16
US5879924A (en) 1999-03-09
IL158301A0 (en) 2004-05-12
CN1228119A (zh) 1999-09-08
DE69737735T2 (de) 2008-01-31

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