DK0917463T3 - Tramadol-flerenhedsformuleringer - Google Patents

Tramadol-flerenhedsformuleringer

Info

Publication number
DK0917463T3
DK0917463T3 DK97935532T DK97935532T DK0917463T3 DK 0917463 T3 DK0917463 T3 DK 0917463T3 DK 97935532 T DK97935532 T DK 97935532T DK 97935532 T DK97935532 T DK 97935532T DK 0917463 T3 DK0917463 T3 DK 0917463T3
Authority
DK
Denmark
Prior art keywords
multiple unit
unit formulations
tramadol
tramadol multiple
formulations
Prior art date
Application number
DK97935532T
Other languages
Danish (da)
English (en)
Inventor
Helmut Momberger
Marc Raber
Dieter Kuhn
Wolfgang Schmid
Original Assignee
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh filed Critical Viatris Gmbh
Application granted granted Critical
Publication of DK0917463T3 publication Critical patent/DK0917463T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
DK97935532T 1996-07-25 1997-07-19 Tramadol-flerenhedsformuleringer DK0917463T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19630035A DE19630035A1 (de) 1996-07-25 1996-07-25 Tramadol Multiple Unit Formulierungen
PCT/EP1997/003934 WO1998004249A2 (de) 1996-07-25 1997-07-19 Tramadol multiple unit formulierungen

Publications (1)

Publication Number Publication Date
DK0917463T3 true DK0917463T3 (da) 2002-06-10

Family

ID=7800815

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97935532T DK0917463T3 (da) 1996-07-25 1997-07-19 Tramadol-flerenhedsformuleringer

Country Status (28)

Country Link
US (2) US5955104A (cs)
EP (1) EP0917463B1 (cs)
JP (1) JP3631762B2 (cs)
KR (1) KR100474793B1 (cs)
CN (1) CN1111402C (cs)
AR (1) AR008002A1 (cs)
AT (1) ATE213408T1 (cs)
AU (1) AU737121B2 (cs)
BG (1) BG63708B1 (cs)
BR (1) BR9710761A (cs)
CA (1) CA2211284C (cs)
CZ (1) CZ296964B6 (cs)
DE (2) DE19630035A1 (cs)
DK (1) DK0917463T3 (cs)
EE (1) EE03742B1 (cs)
ES (1) ES2171268T3 (cs)
HU (1) HU227971B1 (cs)
IL (1) IL127915A (cs)
NO (1) NO324207B1 (cs)
NZ (1) NZ333822A (cs)
PL (1) PL188834B1 (cs)
PT (1) PT917463E (cs)
RU (1) RU2201223C2 (cs)
SK (1) SK285300B6 (cs)
TW (1) TW495363B (cs)
UA (1) UA52679C2 (cs)
WO (1) WO1998004249A2 (cs)
ZA (1) ZA975408B (cs)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen
US6197347B1 (en) * 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
DE19901686A1 (de) * 1999-01-18 2000-07-20 Gruenenthal Gmbh Retardierte Tramadolzubereitungen mit einem lagerstabilen Freisetzungsprofil und Verfahren zu deren Herstellung
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
AU781058B2 (en) 1999-08-31 2005-05-05 Grunenthal Gmbh Delayed-action form of administration containing tramadol saccharinate
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP1623703B1 (en) * 1999-10-29 2011-10-05 Euro-Celtique S.A. Controlled release hydrocodone formulations
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6620431B1 (en) 2000-04-17 2003-09-16 Charles Signorino Shellac film coatings providing release at selected pH and method
US20030157247A1 (en) * 2000-06-14 2003-08-21 Yoshiro Chikami Method for producing coated bioactive granule
WO2002003914A2 (en) * 2000-07-06 2002-01-17 Delsys Pharmaceutical Corporation Improved thyroid hormone formulations
MXPA03003895A (es) 2000-10-30 2003-07-28 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada.
RU2174836C1 (ru) * 2000-12-15 2001-10-20 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая анальгезирующим действием
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
AU2002355266A1 (en) * 2001-07-23 2003-02-17 Brigham And Women's Hospital, Inc. Analgesic methods using endothelin receptor ligands
PE20030527A1 (es) 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
WO2003072089A1 (en) * 2002-02-21 2003-09-04 Biovail Laboratories Inc. Controlled release dosage forms
JP4790415B2 (ja) * 2002-08-15 2011-10-12 ユーロ−セルティーク エス．エイ． 医薬組成物
DE50207738D1 (de) * 2002-11-27 2006-09-14 Oramon Arzneimittel Gmbh & Co Verfahren zur Herstellung von Pellets, enthaltend ein tri- oder tetracyclisches Antidepressivum sowie diese Pellets enthaltende pharmazeutische Zubereitungen
JP2006516969A (ja) * 2003-01-23 2006-07-13 アモレパシフィック コーポレーション 徐放性製剤及びその製造方法
RU2223757C1 (ru) * 2003-03-04 2004-02-20 Закрытое акционерное общество "Брынцалов-А" Препарат, обладающий анальгезирующим действием
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
DE10341414A1 (de) * 2003-09-05 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral zu applizierende Darreichungsform für schwerlösliche saure und amphotere Wirkstoffe
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
CA2874604A1 (en) * 2003-10-03 2005-04-21 Elite Laboratories Inc. Extended release formulations of opioids and method of use thereof
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
EP1771159A4 (en) * 2004-07-22 2009-04-29 Amorepacific Corp SLOW RELEASE PREPARATIONS CONTAINING TOPIRAMATE AND PROCESS FOR PRODUCING THE SAME
BRPI0515600A (pt) 2004-09-01 2008-07-29 Euro Celtique Sa formas farmacêuticas opióides tendo cmédia e auc em estado estável proporcionais à dose e cmax de dose única inferior ao proporcional à dose
MX2007007836A (es) 2004-12-27 2007-08-20 Eisai R&D Man Co Ltd Metodo para estabilizar un farmaco anti-demencia.
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
DK1915137T3 (da) * 2005-08-10 2013-11-04 Add Advanced Drug Delivery Technologies Ltd Oralt præparat med kontrolleret frisætning
MX2008006037A (es) * 2005-11-10 2009-03-03 Circ Pharma Res And Dev Ltd Drogas para el sistema nervioso central para administracion una-vez-al-dia.
US20070185145A1 (en) * 2006-02-03 2007-08-09 Royds Robert B Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
DE602008002073D1 (de) * 2007-03-02 2010-09-16 Farnam Co Inc Wachsähnliches material enthaltende tabletten mit verzögerter freisetzung
MX336789B (es) * 2007-08-13 2016-02-02 Inspirion Delivery Technologies Llc Farmacos resistentes al abuso, metodo de uso y metodo de fabricacion.
CN101095666B (zh) * 2007-08-14 2010-10-06 石药集团欧意药业有限公司 一种盐酸曲马多缓释片剂及其制备方法
CZ300468B6 (cs) * 2007-09-20 2009-05-27 Zentiva, A. S Léková forma obsahující tramadol s kontrolovaným uvolnováním po dobu 24 hodin a zpusob její prípravy
WO2009087690A2 (en) * 2008-01-11 2009-07-16 Jubilant Organosys Limited Multiparticulate extended release pharmaceutical composition of carbamazepine and process for manufacturing the same
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
WO2010028290A1 (en) * 2008-09-04 2010-03-11 Farnam Companies, Inc. Chewable sustained release formulations
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
ES2602604T3 (es) 2008-11-18 2017-02-21 Ucb Biopharma Sprl Formulaciones de liberación prolongada que comprenden un derivado de 2-oxo-1-pirrolidina
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
WO2012003968A1 (en) 2010-07-06 2012-01-12 Grünenthal GmbH Novel gastro- retentive dosage forms comprising a gaba analog and an opioid
ES2698611T3 (es) 2012-07-12 2019-02-05 SpecGx LLC Composiciones farmacéuticas disuasorias del abuso y de liberación prolongada
US10420726B2 (en) 2013-03-15 2019-09-24 Inspirion Delivery Sciences, Llc Abuse deterrent compositions and methods of use
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
IT201800011125A1 (it) * 2018-12-14 2020-06-14 Dpl Pharma S P A Composizioni farmaceutiche orali solide comprendenti matrici monolitiche complesse per la somministrazione cronotropica di medicamenti nel tratto gastroenterico

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5344657A (en) * 1988-04-27 1994-09-06 Elf Sanofi Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
JP3381190B2 (ja) * 1991-09-06 2003-02-24 マクニーラブ・インコーポレーテツド トラマドール物質およびアセトアミノフェンを含んでなる組成物並びにそれの使用
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5411745A (en) * 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
DE4428444A1 (de) * 1994-08-11 1996-02-15 Dresden Arzneimittel Verwendung von Selegilin zur Behandlung von epileptischen Erkrankungen
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen

Also Published As

Publication number Publication date
SK285300B6 (sk) 2006-10-05
BG103158A (en) 1999-08-31
KR100474793B1 (ko) 2005-03-08
EP0917463B1 (de) 2002-02-20
KR20000029530A (ko) 2000-05-25
CN1226824A (zh) 1999-08-25
AU3849197A (en) 1998-02-20
WO1998004249A3 (de) 1998-04-30
BR9710761A (pt) 1999-08-17
HK1020876A1 (en) 2000-05-26
CZ18599A3 (cs) 1999-04-14
CZ296964B6 (cs) 2006-08-16
PT917463E (pt) 2002-07-31
BG63708B1 (bg) 2002-10-31
US5955104A (en) 1999-09-21
ZA975408B (en) 1998-01-05
UA52679C2 (uk) 2003-01-15
IL127915A (en) 2001-08-08
NZ333822A (en) 1999-11-29
CN1111402C (zh) 2003-06-18
RU2201223C2 (ru) 2003-03-27
NO990261D0 (no) 1999-01-21
IL127915A0 (en) 1999-11-30
PL331387A1 (en) 1999-07-05
EE03742B1 (et) 2002-06-17
DE19630035A1 (de) 1998-01-29
ES2171268T3 (es) 2002-09-01
NO990261L (no) 1999-01-21
HUP9903053A2 (hu) 2000-01-28
CA2211284A1 (en) 1998-01-25
ATE213408T1 (de) 2002-03-15
JP3631762B2 (ja) 2005-03-23
EP0917463A2 (de) 1999-05-26
TW495363B (en) 2002-07-21
JP2000515871A (ja) 2000-11-28
PL188834B1 (pl) 2005-04-29
US6436438B1 (en) 2002-08-20
AR008002A1 (es) 1999-11-24
CA2211284C (en) 2001-10-23
NO324207B1 (no) 2007-09-10
HU227971B1 (en) 2012-07-30
HUP9903053A3 (en) 2000-02-28
AU737121B2 (en) 2001-08-09
EE9900031A (et) 1999-08-16
DE59706441D1 (de) 2002-03-28
WO1998004249A2 (de) 1998-02-05
SK9899A3 (en) 1999-09-10

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