DK0871619T3 - Phenylthiazolderivater med antiherpesvirusegenskaber - Google Patents
Phenylthiazolderivater med antiherpesvirusegenskaberInfo
- Publication number
- DK0871619T3 DK0871619T3 DK96945567T DK96945567T DK0871619T3 DK 0871619 T3 DK0871619 T3 DK 0871619T3 DK 96945567 T DK96945567 T DK 96945567T DK 96945567 T DK96945567 T DK 96945567T DK 0871619 T3 DK0871619 T3 DK 0871619T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenylthiazole derivatives
- virus properties
- antiherpes virus
- antiherpes
- properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US943395P | 1995-12-29 | 1995-12-29 | |
| US2320996P | 1996-08-02 | 1996-08-02 | |
| PCT/US1996/019131 WO1997024343A1 (en) | 1995-12-29 | 1996-12-04 | Phenyl thiazole derivatives with anti herpes virus properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0871619T3 true DK0871619T3 (da) | 2003-03-03 |
Family
ID=26679472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96945567T DK0871619T3 (da) | 1995-12-29 | 1996-12-04 | Phenylthiazolderivater med antiherpesvirusegenskaber |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US6057451A (de) |
| EP (1) | EP0871619B1 (de) |
| JP (1) | JP4327249B2 (de) |
| KR (1) | KR19990076964A (de) |
| AR (1) | AR037060A1 (de) |
| AT (1) | ATE227279T1 (de) |
| AU (1) | AU1682897A (de) |
| BG (1) | BG102583A (de) |
| BR (1) | BR9612435A (de) |
| CA (1) | CA2192433C (de) |
| CZ (1) | CZ207298A3 (de) |
| DE (1) | DE69624728T2 (de) |
| DK (1) | DK0871619T3 (de) |
| EA (1) | EA199800611A1 (de) |
| EE (1) | EE9800154A (de) |
| ES (1) | ES2186811T3 (de) |
| HU (1) | HUP9902341A2 (de) |
| IL (1) | IL124436A0 (de) |
| MX (1) | MX9805291A (de) |
| NO (1) | NO982950D0 (de) |
| NZ (1) | NZ331104A (de) |
| PL (1) | PL327582A1 (de) |
| PT (1) | PT871619E (de) |
| SK (1) | SK89398A3 (de) |
| TR (1) | TR199801244T2 (de) |
| WO (1) | WO1997024343A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6100282A (en) | 1998-01-02 | 2000-08-08 | Hoffman-La Roche Inc. | Thiazole derivatives |
| SI0928790T1 (en) * | 1998-01-02 | 2003-06-30 | F. Hoffmann-La Roche Ag | Thiazole derivatives |
| AU1707700A (en) | 1998-10-29 | 2000-05-22 | Bristol-Myers Squibb Company | Novel inhibitors of impdh enzyme |
| WO2000029399A1 (en) * | 1998-11-12 | 2000-05-25 | Boehringer Ingelheim (Canada) Ltd. | Antiherpes compounds |
| US6166028A (en) | 1998-12-09 | 2000-12-26 | American Home Products Corporation | Diaminopuridine-containing thiourea inhibitors of herpes viruses |
| CA2360740A1 (en) | 1999-03-02 | 2000-09-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as reversible inhibitors of cathepsin s |
| AU2914200A (en) * | 1999-03-08 | 2000-09-28 | Bayer Aktiengesellschaft | Thiazolyl urea derivatives and their utilization as antiviral agents |
| DE19927415A1 (de) * | 1999-06-16 | 2000-12-21 | Bayer Ag | Indolinylharnstoffderivate |
| CA2377771A1 (en) * | 1999-07-01 | 2001-01-11 | Ajinomoto Co., Inc. | Heterocyclic compounds and medical use thereof |
| US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
| DOP2000000109A (es) * | 1999-12-23 | 2002-08-30 | Gerald Kleymann | Derivados de tiazolilamida |
| US6867299B2 (en) | 2000-02-24 | 2005-03-15 | Hoffmann-La Roche Inc. | Oxamide IMPDH inhibitors |
| WO2001096874A1 (en) * | 2000-06-15 | 2001-12-20 | Bayer Aktiengesellschaft | Method for identifying compounds with anti-herpes activity |
| DE10038022A1 (de) * | 2000-08-04 | 2002-02-14 | Bayer Ag | Inverse Thiazolylamid-Derivate |
| ATE393141T1 (de) | 2000-08-21 | 2008-05-15 | Pacific Corp | Neue thiourea-derivate und pharmazeutische zusammensetzungen die diese enthalten |
| JP2004506714A (ja) * | 2000-08-21 | 2004-03-04 | パシフィック コーポレーション | 新規チオ尿素化合物及びこれを含有する薬学的組成物 |
| AU2001278821A1 (en) * | 2000-08-21 | 2002-03-04 | Pacific Corporation | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same |
| ES2247177T3 (es) * | 2000-11-10 | 2006-03-01 | Astellas Pharma Inc. | Derivados de amida. |
| DE10129714A1 (de) | 2001-06-22 | 2003-01-02 | Bayer Ag | Topische Anwendung von Thiazolylamiden |
| EP1487796A4 (de) * | 2002-03-28 | 2005-11-16 | Neurogen Corp | Substituierte biarylamide als modulatoren des c5a-rezeptors |
| US6858637B2 (en) | 2002-03-28 | 2005-02-22 | Neurogen Corporation | Substituted biaryl amides as C5a receptor modulators |
| WO2003095435A1 (fr) * | 2002-05-09 | 2003-11-20 | Yamanouchi Pharmaceutical Co., Ltd. | Derives d'amides |
| WO2004042351A2 (en) * | 2002-10-30 | 2004-05-21 | Merck & Co., Inc. | Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity |
| DE10254336A1 (de) * | 2002-11-21 | 2004-06-03 | Merck Patent Gmbh | Carbonsäureamide |
| WO2004067521A1 (en) * | 2003-01-27 | 2004-08-12 | Astellas Pharma Inc. | Thiazole derivatives and their use as vap-1 inhibitors |
| WO2004087138A1 (en) * | 2003-03-31 | 2004-10-14 | Sucampo Ag | Method for treating vascular hyperpermeable disease |
| TW200505894A (en) * | 2003-08-08 | 2005-02-16 | Yamanouchi Pharma Co Ltd | Tetrahydro-2H-thiopyran-4-carboxamide derivative |
| FR2860514A1 (fr) * | 2003-10-03 | 2005-04-08 | Sanofi Synthelabo | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique |
| KR20050039573A (ko) * | 2003-10-23 | 2005-04-29 | 주식회사 태평양 | 티오우레아계 유도체의 용해성과 생체이용률이 개선된약제학적 조성물 |
| WO2005051318A2 (en) * | 2003-11-24 | 2005-06-09 | Viropharma Incorporated | Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
| EP1730196B1 (de) | 2004-03-12 | 2010-12-22 | Vasgene Therapeutics, Inc. | Ephb4-bindende antikörper zur inhibierung von angiogenese und tumorwachstum |
| JP5011739B2 (ja) * | 2005-02-03 | 2012-08-29 | アステラス製薬株式会社 | テトラヒドロ−２ｈ−チオピラン−４−カルボキサミド誘導体を含有する医薬組成物 |
| DE102005014248A1 (de) | 2005-03-30 | 2006-10-05 | Aicuris Gmbh & Co. Kg | Pharmazeutische Zubereitung von N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamid |
| UA92746C2 (en) | 2005-05-09 | 2010-12-10 | Акилайон Фармасьютикалз, Инк. | Thiazole compounds and methods of use |
| WO2007002639A2 (en) * | 2005-06-24 | 2007-01-04 | Migenix Inc. | Non-nucleoside anti-hepacivirus agents and uses thereof |
| WO2007098826A2 (en) * | 2006-01-18 | 2007-09-07 | Siena Biotech S.P.A. | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof |
| KR101097533B1 (ko) * | 2006-08-30 | 2011-12-22 | 에프. 호프만-라 로슈 아게 | Ｇｌｙｔ-1 억제제 |
| TW200906826A (en) * | 2007-06-12 | 2009-02-16 | Genelabs Tech Inc | Anti-viral inhibitors and methods of use |
| JPWO2010047295A1 (ja) | 2008-10-20 | 2012-03-22 | アステラス製薬株式会社 | 帯状疱疹関連痛の予防又は治療薬 |
| US8629157B2 (en) | 2009-01-05 | 2014-01-14 | Boehringer Ingelheim International Gmbh | Pyrrolidine compounds which modulate the CB2 receptor |
| US8822515B2 (en) | 2009-10-16 | 2014-09-02 | University Of Maryland, Baltimore County | Heterocyclic benzoxazole compositions as inhibitors of hepatitis C virus |
| WO2012113920A1 (en) | 2011-02-24 | 2012-08-30 | Katholieke Universiteit Leuven | Arylsulfone derivatives with activity against human betaherpesviruses |
| KR101399484B1 (ko) * | 2011-07-14 | 2014-05-29 | 한국화학연구원 | 허피스바이러스 엑소뉴클리에이즈 활성 억제 물질을 유효성분으로 함유하는 항허피스바이러스용 약학적 조성물 |
| UY35772A (es) | 2013-10-14 | 2015-05-29 | Bayer Cropscience Ag | Nuevos compuestos plaguicidas |
| IL308138A (en) | 2014-11-10 | 2023-12-01 | Evrys Bio Llc | Preparations against human cytomegalovirus and methods of treating it |
| EP3256461B1 (de) * | 2015-02-13 | 2023-09-13 | Azienda Ospedaliera Universitaria Senese | Harnstoff- und sulfonamidderivate als humane helikase ddx3-hemmer zur behandlung von viruserkrankungen |
| WO2017174640A1 (en) | 2016-04-06 | 2017-10-12 | Innovatives Molecules Gmbh | Aminothiazole derivatives useful as antiviral agents |
| WO2018132372A1 (en) | 2017-01-10 | 2018-07-19 | Sanford Burnham Prebys Medical Discovery Institute | Small molecule activators of nicotinamide phosphoribosyltransferase (nampt) and uses thereof |
| AR113344A1 (es) | 2017-10-05 | 2020-04-22 | Innovative Molecules Gmbh | Enantiómeros de una serie de compuestos antivirales |
| US11918568B2 (en) | 2018-07-05 | 2024-03-05 | Sanford Burnham Prebys Medical Discovery Institute | Fused ring compound having urea structure |
| EP3849979A1 (de) | 2018-09-12 | 2021-07-21 | Novartis AG | Antivirale pyridopyrazindionverbindungen |
| US11377425B1 (en) * | 2018-12-19 | 2022-07-05 | Leo Pharma A/S | Small molecule modulators of IL-17 |
| AR120045A1 (es) | 2019-09-26 | 2022-01-26 | Novartis Ag | Compuestos antivirales de pirazolopiridinona |
| WO2024047508A1 (en) | 2022-08-29 | 2024-03-07 | Assembly Biosciences, Inc. | Pharmaceutical compositions for herpes virus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3629247A (en) * | 1969-06-06 | 1971-12-21 | Pfizer | Thiazoline and 5 6-dihydro-4h-1 3-thiazine antiviral agents |
| US4746669A (en) * | 1985-12-23 | 1988-05-24 | Merck & Co., Inc. | Substituted thiazoles as immunoregulants |
| JPH075579B2 (ja) * | 1986-09-01 | 1995-01-25 | 吉富製薬株式会社 | アミノチアゾ−ル化合物 |
| MX174210B (es) * | 1987-02-17 | 1994-04-28 | Pfizer | Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos |
| WO1990006303A1 (en) * | 1988-12-02 | 1990-06-14 | Pfizer Inc. | Arylpiperidine derivatives |
| FR2656610B1 (fr) * | 1989-12-29 | 1992-05-07 | Sanofi Sa | Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique. |
| US5077409A (en) * | 1990-05-04 | 1991-12-31 | American Cyanamid Company | Method of preparing bis-aryl amide and urea antagonists of platelet activating factor |
| US5128351A (en) * | 1990-05-04 | 1992-07-07 | American Cyanamid Company | Bis-aryl amide and urea antagonists of platelet activating factor |
| AU1347292A (en) * | 1991-01-18 | 1992-08-27 | Oncogene Science, Inc. | Methods of transcriptionally modulating gene expression of viral genes and other genes |
| GB9125970D0 (en) * | 1991-12-06 | 1992-02-05 | Fujisawa Pharmaceutical Co | New compounds |
| TW288010B (de) * | 1992-03-05 | 1996-10-11 | Pfizer | |
| US5342851A (en) * | 1992-10-07 | 1994-08-30 | Mcneil-Ppc, Inc. | Substituted thiazole derivatives useful as platelet aggregation inhibitors |
| GB2276164A (en) * | 1993-03-17 | 1994-09-21 | Glaxo Group Ltd | Aniline and benzanilide derivatives |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
| AU701776B2 (en) * | 1994-05-27 | 1999-02-04 | Merck & Co., Inc. | Compounds for inhibiting osteoclast-mediated bone resorption |
| WO1999042455A1 (en) * | 1998-02-19 | 1999-08-26 | Tularik Inc. | Antiviral agents |
-
1996
- 1996-12-04 DE DE69624728T patent/DE69624728T2/de not_active Expired - Lifetime
- 1996-12-04 BR BR9612435A patent/BR9612435A/pt unknown
- 1996-12-04 IL IL12443696A patent/IL124436A0/xx unknown
- 1996-12-04 EE EE9800154A patent/EE9800154A/xx unknown
- 1996-12-04 PL PL96327582A patent/PL327582A1/xx unknown
- 1996-12-04 US US08/759,201 patent/US6057451A/en not_active Expired - Lifetime
- 1996-12-04 JP JP52432597A patent/JP4327249B2/ja not_active Expired - Fee Related
- 1996-12-04 AU AU16828/97A patent/AU1682897A/en not_active Abandoned
- 1996-12-04 EA EA199800611A patent/EA199800611A1/ru unknown
- 1996-12-04 SK SK893-98A patent/SK89398A3/sk unknown
- 1996-12-04 NZ NZ331104A patent/NZ331104A/xx unknown
- 1996-12-04 PT PT96945567T patent/PT871619E/pt unknown
- 1996-12-04 ES ES96945567T patent/ES2186811T3/es not_active Expired - Lifetime
- 1996-12-04 KR KR1019980705092A patent/KR19990076964A/ko not_active Application Discontinuation
- 1996-12-04 WO PCT/US1996/019131 patent/WO1997024343A1/en active IP Right Grant
- 1996-12-04 AT AT96945567T patent/ATE227279T1/de active
- 1996-12-04 TR TR1998/01244T patent/TR199801244T2/xx unknown
- 1996-12-04 CZ CZ982072A patent/CZ207298A3/cs unknown
- 1996-12-04 DK DK96945567T patent/DK0871619T3/da active
- 1996-12-04 HU HU9902341A patent/HUP9902341A2/hu unknown
- 1996-12-04 EP EP96945567A patent/EP0871619B1/de not_active Expired - Lifetime
- 1996-12-09 CA CA002192433A patent/CA2192433C/en not_active Expired - Fee Related
- 1996-12-30 AR ARP960105968A patent/AR037060A1/es not_active Withdrawn
-
1998
- 1998-06-25 NO NO982950A patent/NO982950D0/no not_active Application Discontinuation
- 1998-06-26 BG BG102583A patent/BG102583A/xx active Pending
- 1998-06-29 MX MX9805291A patent/MX9805291A/es not_active IP Right Cessation
-
1999
- 1999-12-08 US US09/456,857 patent/US6348477B1/en not_active Expired - Lifetime
-
2000
- 2000-10-10 US US09/685,686 patent/US6458959B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BR9612435A (pt) | 1999-07-13 |
| DE69624728D1 (de) | 2002-12-12 |
| SK89398A3 (en) | 1998-11-04 |
| BG102583A (en) | 1999-06-30 |
| NO982950L (no) | 1998-06-25 |
| NZ331104A (en) | 2000-03-27 |
| US6458959B1 (en) | 2002-10-01 |
| CZ207298A3 (cs) | 1998-11-11 |
| EP0871619B1 (de) | 2002-11-06 |
| JP2000502702A (ja) | 2000-03-07 |
| CA2192433A1 (en) | 1997-06-30 |
| PL327582A1 (en) | 1998-12-21 |
| US6348477B1 (en) | 2002-02-19 |
| WO1997024343A1 (en) | 1997-07-10 |
| DE69624728T2 (de) | 2003-07-10 |
| KR19990076964A (ko) | 1999-10-25 |
| TR199801244T2 (xx) | 1998-12-21 |
| US6057451A (en) | 2000-05-02 |
| NO982950D0 (no) | 1998-06-25 |
| ES2186811T3 (es) | 2003-05-16 |
| AR037060A1 (es) | 2004-10-20 |
| JP4327249B2 (ja) | 2009-09-09 |
| MX9805291A (es) | 1998-10-31 |
| EE9800154A (et) | 1998-12-15 |
| IL124436A0 (en) | 1998-12-06 |
| ATE227279T1 (de) | 2002-11-15 |
| HUP9902341A2 (hu) | 1999-10-28 |
| CA2192433C (en) | 2008-01-08 |
| EP0871619A1 (de) | 1998-10-21 |
| PT871619E (pt) | 2003-03-31 |
| EA199800611A1 (ru) | 1999-04-29 |
| AU1682897A (en) | 1997-07-28 |
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