HUP9902341A2 - Herpeszvírus elleni hatású fenil-tiazol-származékok, előállításuk és alkalmazásuk, a vegyületeket tartalmazó gyógyszerkészítmények - Google Patents
Herpeszvírus elleni hatású fenil-tiazol-származékok, előállításuk és alkalmazásuk, a vegyületeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP9902341A2 HUP9902341A2 HU9902341A HUP9902341A HUP9902341A2 HU P9902341 A2 HUP9902341 A2 HU P9902341A2 HU 9902341 A HU9902341 A HU 9902341A HU P9902341 A HUP9902341 A HU P9902341A HU P9902341 A2 HUP9902341 A2 HU P9902341A2
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- preparation
- pharmaceutical compositions
- compositions containing
- herpes virus
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- WYKHSBAVLOPISI-UHFFFAOYSA-N 2-phenyl-1,3-thiazole Chemical class C1=CSC(C=2C=CC=CC=2)=N1 WYKHSBAVLOPISI-UHFFFAOYSA-N 0.000 title 1
- 230000003602 anti-herpes Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
A találmány szerinti vegyületek (G) általánős képletében Rhidrőgénatőm, alkil- vagy adőtt esetben szűbsztitűált aminőcsőpőrt; ésZ megfelelően szűbsztitűált (aminő-acil)-aminő-, űreidő-,karbamőil, karbamőil-alkőxi- vagy (acil-aminő)-etil-csőpőrt. (G) ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US943395P | 1995-12-29 | 1995-12-29 | |
US2320996P | 1996-08-02 | 1996-08-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP9902341A2 true HUP9902341A2 (hu) | 1999-10-28 |
Family
ID=26679472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9902341A HUP9902341A2 (hu) | 1995-12-29 | 1996-12-04 | Herpeszvírus elleni hatású fenil-tiazol-származékok, előállításuk és alkalmazásuk, a vegyületeket tartalmazó gyógyszerkészítmények |
Country Status (26)
Country | Link |
---|---|
US (3) | US6057451A (hu) |
EP (1) | EP0871619B1 (hu) |
JP (1) | JP4327249B2 (hu) |
KR (1) | KR19990076964A (hu) |
AR (1) | AR037060A1 (hu) |
AT (1) | ATE227279T1 (hu) |
AU (1) | AU1682897A (hu) |
BG (1) | BG102583A (hu) |
BR (1) | BR9612435A (hu) |
CA (1) | CA2192433C (hu) |
CZ (1) | CZ207298A3 (hu) |
DE (1) | DE69624728T2 (hu) |
DK (1) | DK0871619T3 (hu) |
EA (1) | EA199800611A1 (hu) |
EE (1) | EE9800154A (hu) |
ES (1) | ES2186811T3 (hu) |
HU (1) | HUP9902341A2 (hu) |
IL (1) | IL124436A0 (hu) |
MX (1) | MX9805291A (hu) |
NO (1) | NO982950D0 (hu) |
NZ (1) | NZ331104A (hu) |
PL (1) | PL327582A1 (hu) |
PT (1) | PT871619E (hu) |
SK (1) | SK89398A3 (hu) |
TR (1) | TR199801244T2 (hu) |
WO (1) | WO1997024343A1 (hu) |
Cited By (1)
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---|---|---|---|---|
US6555561B2 (en) | 1998-12-09 | 2003-04-29 | Wyeth | Diaminopyridine-containing thiourea inhibitors of herpes viruses |
Families Citing this family (53)
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US6100282A (en) * | 1998-01-02 | 2000-08-08 | Hoffman-La Roche Inc. | Thiazole derivatives |
EP0928790B1 (en) * | 1998-01-02 | 2003-03-05 | F. Hoffmann-La Roche Ag | Thiazole derivatives |
AU1707700A (en) | 1998-10-29 | 2000-05-22 | Bristol-Myers Squibb Company | Novel inhibitors of impdh enzyme |
WO2000029399A1 (en) * | 1998-11-12 | 2000-05-25 | Boehringer Ingelheim (Canada) Ltd. | Antiherpes compounds |
EP1159273A1 (en) | 1999-03-02 | 2001-12-05 | Boehringer Ingelheim Pharmaceuticals Inc. | Compounds useful as reversible inhibitors of cathepsin s |
JP2002539119A (ja) * | 1999-03-08 | 2002-11-19 | バイエル アクチェンゲゼルシャフト | チアゾリルウレア誘導体および抗ウイルス剤としてのそれらの使用 |
DE19927415A1 (de) * | 1999-06-16 | 2000-12-21 | Bayer Ag | Indolinylharnstoffderivate |
EP1193255A4 (en) * | 1999-07-01 | 2002-08-07 | Ajinomoto Kk | HETEROCYCLIC COMPOUNDS AND THEIR APPLICATIONS IN MEDICINE |
US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
DOP2000000109A (es) | 1999-12-23 | 2002-08-30 | Gerald Kleymann | Derivados de tiazolilamida |
US6867299B2 (en) * | 2000-02-24 | 2005-03-15 | Hoffmann-La Roche Inc. | Oxamide IMPDH inhibitors |
AU2000259734A1 (en) * | 2000-06-15 | 2001-12-24 | Gerald Kleymann | Method for identifying compounds with anti-herpes activity |
DE10038022A1 (de) * | 2000-08-04 | 2002-02-14 | Bayer Ag | Inverse Thiazolylamid-Derivate |
EP1311477A4 (en) * | 2000-08-21 | 2005-01-12 | Pacific Corp | NEW THIOCARBAMIDIC ACID DERIVATIVES AND MEDICAMENTS CONTAINING THEM |
EP1303483B1 (en) * | 2000-08-21 | 2008-04-23 | Pacific Corporation | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
US7067553B2 (en) * | 2000-08-21 | 2006-06-27 | Pacific Corporation | Thiourea compounds and the pharmaceutical compositions containing the same |
ES2247177T3 (es) * | 2000-11-10 | 2006-03-01 | Astellas Pharma Inc. | Derivados de amida. |
DE10129714A1 (de) | 2001-06-22 | 2003-01-02 | Bayer Ag | Topische Anwendung von Thiazolylamiden |
CA2479928A1 (en) * | 2002-03-28 | 2003-10-09 | Neurogen Corporation | Substituted biaryl amides as c5a receptor modulators |
US6858637B2 (en) | 2002-03-28 | 2005-02-22 | Neurogen Corporation | Substituted biaryl amides as C5a receptor modulators |
AU2003235889A1 (en) * | 2002-05-09 | 2003-11-11 | Rational Drug Design Laboratories | Amide derivatives |
EP1558253A4 (en) * | 2002-10-30 | 2007-07-25 | Merck & Co Inc | PIPERIDINYL ALPHA AMINOAMIDE MODULATORS DERCHEMOKIN RECEPTOR ACTIVITY |
DE10254336A1 (de) * | 2002-11-21 | 2004-06-03 | Merck Patent Gmbh | Carbonsäureamide |
KR101154163B1 (ko) * | 2003-01-27 | 2012-06-14 | 아스텔라스세이야쿠 가부시키가이샤 | 티아졸 유도체 및 vap-1 저해제로서의 용도 |
JP4758337B2 (ja) * | 2003-03-31 | 2011-08-24 | 株式会社アールテック・ウエノ | 血管透過性亢進疾患を治療する方法 |
TW200505894A (en) * | 2003-08-08 | 2005-02-16 | Yamanouchi Pharma Co Ltd | Tetrahydro-2H-thiopyran-4-carboxamide derivative |
FR2860514A1 (fr) * | 2003-10-03 | 2005-04-08 | Sanofi Synthelabo | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique |
KR20050039573A (ko) * | 2003-10-23 | 2005-04-29 | 주식회사 태평양 | 티오우레아계 유도체의 용해성과 생체이용률이 개선된약제학적 조성물 |
WO2005051318A2 (en) * | 2003-11-24 | 2005-06-09 | Viropharma Incorporated | Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
WO2005090406A2 (en) | 2004-03-12 | 2005-09-29 | Vasgene Therapeutics, Inc. | Antibodies binding to ephb4 for inhibiting angiogenesis and tumor growth |
JP5011739B2 (ja) * | 2005-02-03 | 2012-08-29 | アステラス製薬株式会社 | テトラヒドロ−2h−チオピラン−4−カルボキサミド誘導体を含有する医薬組成物 |
DE102005014248A1 (de) | 2005-03-30 | 2006-10-05 | Aicuris Gmbh & Co. Kg | Pharmazeutische Zubereitung von N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamid |
UA92746C2 (en) | 2005-05-09 | 2010-12-10 | Акилайон Фармасьютикалз, Инк. | Thiazole compounds and methods of use |
EP1910279A2 (en) * | 2005-06-24 | 2008-04-16 | Migenix Inc. | Non-nucleoside anti-hepacivirus agents and uses thereof |
JP2009523748A (ja) * | 2006-01-18 | 2009-06-25 | シエナ ビオテク ソシエタ ペル アチオニ | α7ニコチン性アセチルコリン受容体の調節物質およびそれらの治療への使用 |
ES2392105T3 (es) * | 2006-08-30 | 2012-12-04 | F. Hoffmann-La Roche Ag | Inhibidores de GlyT-1 |
TW200906826A (en) * | 2007-06-12 | 2009-02-16 | Genelabs Tech Inc | Anti-viral inhibitors and methods of use |
EP2351565A1 (en) | 2008-10-20 | 2011-08-03 | Astellas Pharma Inc. | Medicine for preventing or treating pain related to herpes zoster |
US8629157B2 (en) | 2009-01-05 | 2014-01-14 | Boehringer Ingelheim International Gmbh | Pyrrolidine compounds which modulate the CB2 receptor |
WO2011047390A2 (en) | 2009-10-16 | 2011-04-21 | University Of Maryland, Baltimore County | Heterocyclic benzoxazole compositions as inhibitors of hepatitis c virus |
WO2012113920A1 (en) | 2011-02-24 | 2012-08-30 | Katholieke Universiteit Leuven | Arylsulfone derivatives with activity against human betaherpesviruses |
KR101399484B1 (ko) * | 2011-07-14 | 2014-05-29 | 한국화학연구원 | 허피스바이러스 엑소뉴클리에이즈 활성 억제 물질을 유효성분으로 함유하는 항허피스바이러스용 약학적 조성물 |
UY35772A (es) | 2013-10-14 | 2015-05-29 | Bayer Cropscience Ag | Nuevos compuestos plaguicidas |
JP6698083B2 (ja) | 2014-11-10 | 2020-05-27 | エヴリース・バイオ, エルエルシーEvrys Bio, LLC | 抗hcmvの組成物及び方法 |
JP6749344B2 (ja) * | 2015-02-13 | 2020-09-02 | アジエンダ・オスペダリエラ・ウニベルシタリア・セネーゼ | 治療剤としてのヒトヘリカーゼddx3阻害剤 |
ES2834051T3 (es) | 2016-04-06 | 2021-06-16 | Innovative Molecules Gmbh | Derivados de aminotiazol útiles como agentes antivirales |
WO2018132372A1 (en) * | 2017-01-10 | 2018-07-19 | Sanford Burnham Prebys Medical Discovery Institute | Small molecule activators of nicotinamide phosphoribosyltransferase (nampt) and uses thereof |
AU2018344471B2 (en) | 2017-10-05 | 2022-09-29 | Innovative Molecules Gmbh | Enantiomers of substituted thiazoles as antiviral compounds |
CN112654608A (zh) | 2018-07-05 | 2021-04-13 | 桑福德伯纳姆普利斯医学发现研究所 | 具有脲结构的稠环化合物 |
CA3112326A1 (en) | 2018-09-12 | 2020-03-19 | Novartis Ag | Antiviral pyridopyrazinedione compounds |
TW202039473A (zh) | 2018-12-19 | 2020-11-01 | 丹麥商理奧藥品公司 | Il-17的小分子調節劑 |
TW202126649A (zh) | 2019-09-26 | 2021-07-16 | 瑞士商諾華公司 | 抗病毒吡唑并吡啶酮化合物 |
WO2024047508A1 (en) | 2022-08-29 | 2024-03-07 | Assembly Biosciences, Inc. | Pharmaceutical compositions for herpes virus |
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AU701776B2 (en) * | 1994-05-27 | 1999-02-04 | Merck & Co., Inc. | Compounds for inhibiting osteoclast-mediated bone resorption |
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-
1996
- 1996-12-04 JP JP52432597A patent/JP4327249B2/ja not_active Expired - Fee Related
- 1996-12-04 SK SK893-98A patent/SK89398A3/sk unknown
- 1996-12-04 ES ES96945567T patent/ES2186811T3/es not_active Expired - Lifetime
- 1996-12-04 IL IL12443696A patent/IL124436A0/xx unknown
- 1996-12-04 TR TR1998/01244T patent/TR199801244T2/xx unknown
- 1996-12-04 WO PCT/US1996/019131 patent/WO1997024343A1/en active IP Right Grant
- 1996-12-04 PT PT96945567T patent/PT871619E/pt unknown
- 1996-12-04 HU HU9902341A patent/HUP9902341A2/hu unknown
- 1996-12-04 EE EE9800154A patent/EE9800154A/xx unknown
- 1996-12-04 PL PL96327582A patent/PL327582A1/xx unknown
- 1996-12-04 DE DE69624728T patent/DE69624728T2/de not_active Expired - Lifetime
- 1996-12-04 US US08/759,201 patent/US6057451A/en not_active Expired - Lifetime
- 1996-12-04 AU AU16828/97A patent/AU1682897A/en not_active Abandoned
- 1996-12-04 EP EP96945567A patent/EP0871619B1/en not_active Expired - Lifetime
- 1996-12-04 NZ NZ331104A patent/NZ331104A/xx unknown
- 1996-12-04 AT AT96945567T patent/ATE227279T1/de active
- 1996-12-04 KR KR1019980705092A patent/KR19990076964A/ko not_active Application Discontinuation
- 1996-12-04 EA EA199800611A patent/EA199800611A1/ru unknown
- 1996-12-04 CZ CZ982072A patent/CZ207298A3/cs unknown
- 1996-12-04 DK DK96945567T patent/DK0871619T3/da active
- 1996-12-04 BR BR9612435A patent/BR9612435A/pt unknown
- 1996-12-09 CA CA002192433A patent/CA2192433C/en not_active Expired - Fee Related
- 1996-12-30 AR ARP960105968A patent/AR037060A1/es not_active Withdrawn
-
1998
- 1998-06-25 NO NO982950A patent/NO982950D0/no not_active Application Discontinuation
- 1998-06-26 BG BG102583A patent/BG102583A/xx active Pending
- 1998-06-29 MX MX9805291A patent/MX9805291A/es not_active IP Right Cessation
-
1999
- 1999-12-08 US US09/456,857 patent/US6348477B1/en not_active Expired - Lifetime
-
2000
- 2000-10-10 US US09/685,686 patent/US6458959B1/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6555561B2 (en) | 1998-12-09 | 2003-04-29 | Wyeth | Diaminopyridine-containing thiourea inhibitors of herpes viruses |
Also Published As
Publication number | Publication date |
---|---|
BR9612435A (pt) | 1999-07-13 |
MX9805291A (es) | 1998-10-31 |
JP2000502702A (ja) | 2000-03-07 |
DE69624728D1 (de) | 2002-12-12 |
EP0871619B1 (en) | 2002-11-06 |
ES2186811T3 (es) | 2003-05-16 |
DE69624728T2 (de) | 2003-07-10 |
PL327582A1 (en) | 1998-12-21 |
AU1682897A (en) | 1997-07-28 |
JP4327249B2 (ja) | 2009-09-09 |
NO982950L (no) | 1998-06-25 |
WO1997024343A1 (en) | 1997-07-10 |
PT871619E (pt) | 2003-03-31 |
DK0871619T3 (da) | 2003-03-03 |
NZ331104A (en) | 2000-03-27 |
KR19990076964A (ko) | 1999-10-25 |
CZ207298A3 (cs) | 1998-11-11 |
IL124436A0 (en) | 1998-12-06 |
BG102583A (en) | 1999-06-30 |
US6458959B1 (en) | 2002-10-01 |
EA199800611A1 (ru) | 1999-04-29 |
TR199801244T2 (xx) | 1998-12-21 |
AR037060A1 (es) | 2004-10-20 |
US6057451A (en) | 2000-05-02 |
SK89398A3 (en) | 1998-11-04 |
US6348477B1 (en) | 2002-02-19 |
ATE227279T1 (de) | 2002-11-15 |
NO982950D0 (no) | 1998-06-25 |
CA2192433A1 (en) | 1997-06-30 |
CA2192433C (en) | 2008-01-08 |
EP0871619A1 (en) | 1998-10-21 |
EE9800154A (et) | 1998-12-15 |
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