DK1944362T3
(da)
*
|
1997-09-05 |
2016-01-25 |
Genzyme Corp |
Fremgangsmåder til fremstilling af hjælpevirusfri præparater med høj titer af rekombinante AAV-vektorer
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
US6995006B2
(en)
|
1997-09-05 |
2006-02-07 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
EP1930418B1
(en)
|
1998-09-04 |
2015-04-08 |
Genzyme Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
ATE332364T1
(de)
*
|
1999-02-22 |
2006-07-15 |
Transgene Sa |
Verfahren zur gewinnung von purifizierter virenzuammensetzung
|
US6464976B1
(en)
|
1999-09-07 |
2002-10-15 |
Canji, Inc. |
Methods and compositions for reducing immune response
|
US6436402B1
(en)
*
|
1999-10-15 |
2002-08-20 |
Merck & Co., Inc. |
Process for making human papillomavirus virus-like particles with improved properties
|
EP1681299B1
(en)
|
2000-03-27 |
2009-11-11 |
Genetics Institute, LLC |
Methods for purifying highly anionic proteins
|
EP1404428B1
(en)
*
|
2001-06-05 |
2006-07-19 |
Genetics Institute, LLC |
Methods for purifying highly anionic proteins
|
US6833238B2
(en)
|
2002-01-04 |
2004-12-21 |
Applera Corporation |
Petal-array support for use with microplates
|
US20040016702A1
(en)
*
|
2002-07-26 |
2004-01-29 |
Applera Corporation |
Device and method for purification of nucleic acids
|
CA2529053A1
(en)
*
|
2003-06-18 |
2004-12-29 |
Onyx Pharmaceuticals, Inc. |
Method for purifying virus
|
WO2004113518A1
(en)
*
|
2003-06-20 |
2004-12-29 |
Microbix Biosystems Inc. |
Improvements in virus production
|
US7479222B2
(en)
*
|
2004-02-05 |
2009-01-20 |
Millipore Corporation |
Porous adsorptive or chromatographic media
|
US20050181378A1
(en)
*
|
2004-02-18 |
2005-08-18 |
Applera Corporation |
Polyelectrolyte-coated size-exclusion ion-exchange particles
|
US20060160122A1
(en)
*
|
2004-02-18 |
2006-07-20 |
Applera Corporation |
Polyelectrolyte-coated size-exclusion ion-exchange particles
|
US20050196856A1
(en)
*
|
2004-02-18 |
2005-09-08 |
Applera Corporation |
Polyelectrolyte-coated size-exclusion ion-exchange particles
|
EP1718738A2
(en)
*
|
2004-02-23 |
2006-11-08 |
Crucell Holland B.V. |
Virus purification methods
|
NZ551448A
(en)
*
|
2004-05-20 |
2011-02-25 |
Novartis Vaccines & Diagnostic |
Analysis of liquid chromotography eluates
|
JP4896021B2
(ja)
|
2004-05-21 |
2012-03-14 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド |
呼吸器系病原体ワクチンのためのアルファウイルスベクター
|
CN101155915B
(zh)
*
|
2005-04-11 |
2013-12-04 |
克鲁塞尔荷兰公司 |
利用超滤进行病毒纯化
|
US20070111309A1
(en)
*
|
2005-10-04 |
2007-05-17 |
Daelli Marcelo G |
Vero cell line adapted to grow in suspension
|
CN101426905B
(zh)
|
2006-04-20 |
2013-03-27 |
惠氏公司 |
从细胞培养物分离纯化的水泡性口炎病毒的纯化方法
|
EP1878791A1
(en)
*
|
2006-07-11 |
2008-01-16 |
Bia Separations D.O.O. |
Method for influenza virus purification
|
WO2008091283A2
(en)
|
2006-07-13 |
2008-07-31 |
Institute For Advanced Study |
Viral inhibitory nucleotide sequences and vaccines
|
US8481298B2
(en)
|
2006-09-29 |
2013-07-09 |
Ge Healthcare Bio-Sciences Ab |
Separation matrix for viral purification
|
EP2679237A1
(en)
|
2006-11-29 |
2014-01-01 |
Nationwide Children's Hospital |
Myostatin inhibition for enhancing muscle and/or improving muscle function
|
US9433922B2
(en)
*
|
2007-08-14 |
2016-09-06 |
Emd Millipore Corporation |
Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
|
US20090130738A1
(en)
*
|
2007-11-19 |
2009-05-21 |
Mikhail Kozlov |
Media for membrane ion exchange chromatography
|
US11219696B2
(en)
|
2008-12-19 |
2022-01-11 |
Nationwide Children's Hospital |
Delivery of polynucleotides using recombinant AAV9
|
US9415121B2
(en)
|
2008-12-19 |
2016-08-16 |
Nationwide Children's Hospital |
Delivery of MECP2 polynucleotide using recombinant AAV9
|
US20110293660A1
(en)
|
2009-02-06 |
2011-12-01 |
Bruno Rene Andre |
Novel method
|
FR2944292B1
(fr)
|
2009-04-08 |
2013-08-23 |
Sanofi Pasteur |
Procede de purification du virus rabique
|
HUE038451T2
(hu)
|
2009-08-06 |
2018-10-29 |
Hoffmann La Roche |
Eljárás vírus eltávolításának javítására fehérjetisztítás során
|
JP2013506672A
(ja)
|
2009-10-02 |
2013-02-28 |
トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク |
魚類レオウイルス免疫原性組成物
|
US8557253B2
(en)
|
2009-10-07 |
2013-10-15 |
Sanofi Pasteur Sa |
Stabilizing excipient for inactivated whole virus vaccine
|
SG184833A1
(en)
|
2010-04-14 |
2012-11-29 |
Emd Millipore Corp |
Methods of producing high titer, high purity virus stocks and methods of use thereof
|
KR20150023923A
(ko)
|
2010-07-30 |
2015-03-05 |
이엠디 밀리포어 코포레이션 |
크로마토그래피 매질 및 방법
|
DE102010046817A1
(de)
|
2010-09-28 |
2012-03-29 |
Sartorius Stedim Biotech Gmbh |
Verfahren zur Abtrennung von Viren aus einem Kontaminanten enthaltenden flüssigen Medium
|
EP2643045A4
(en)
|
2010-11-23 |
2016-01-13 |
Presage Biosciences Inc |
THERAPEUTIC PROCESSES AND COMPOSITIONS FOR SOLID FORM DELIVERY
|
EP3495472B1
(en)
|
2011-04-21 |
2023-11-15 |
Nationwide Children's Hospital, Inc. |
Recombinant virus products and methods for inhibition of expression of myotilin
|
US10196636B2
(en)
|
2011-04-21 |
2019-02-05 |
Nationwide Children's Hospital, Inc. |
Recombinant virus products and methods for inhibition of expression of myotilin
|
US20130039888A1
(en)
|
2011-06-08 |
2013-02-14 |
Nationwide Children's Hospital Inc. |
Products and methods for delivery of polynucleotides by adeno-associated virus for lysosomal storage disorders
|
CA3106285A1
(en)
|
2011-07-25 |
2013-01-31 |
Nationwide Children's Hospital, Inc. |
Recombinant virus products and methods for inhibition of expression of dux4
|
WO2013078316A1
(en)
|
2011-11-23 |
2013-05-30 |
Nationwide Children's Hospital, Inc. |
Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides
|
EP3415167B1
(en)
|
2012-08-01 |
2024-05-29 |
Nationwide Children's Hospital |
Intrathecal delivery of recombinant adeno-associated virus 9
|
CA2885216A1
(en)
|
2012-09-17 |
2014-03-20 |
The Research Institute At Nationwide Children's Hospital |
Compositions and methods for treating amyotrophic lateral sclerosis
|
CN104968403A
(zh)
|
2012-09-17 |
2015-10-07 |
格雷斯公司 |
色谱介质和装置
|
WO2014129964A2
(en)
*
|
2013-02-22 |
2014-08-28 |
Agency For Science, Technology And Research |
Chromatographic purification of virus preparations with negatively charged particles
|
CA2909807C
(en)
|
2013-04-20 |
2023-08-08 |
Research Institute At Nationwide Children's Hospital |
Recombinant adeno-associated virus delivery of exon 2-targeted u7snrna polynucleotide constructs
|
EP4219727A3
(en)
|
2013-08-27 |
2023-09-06 |
Research Institute at Nationwide Children's Hospital |
Products and methods for treatment of amyotrophic lateral sclerosis
|
WO2015069647A1
(en)
|
2013-11-05 |
2015-05-14 |
The Research Institute At Nationwide Children's Hospital |
COMPOSITIONS AND METHODS FOR INHIBITING NF- kB AND SOD-1 TO TREAT AMYOTROPHIC LATERAL SCLEROSIS
|
IL230970A0
(en)
|
2014-02-13 |
2014-09-30 |
Univ Ramot |
Tilapia virus vaccines
|
US10047130B2
(en)
|
2014-03-18 |
2018-08-14 |
Washington University |
Methods and compositions for red-shifted chromophore substitution for optogenetic applications
|
JP6986444B2
(ja)
|
2014-08-09 |
2021-12-22 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
Dmd遺伝子のエクソン5内の内部リボソーム進入部位を活性化するための方法及び材料
|
CN106794389A
(zh)
|
2014-09-02 |
2017-05-31 |
Emd密理博公司 |
具有纳米原纤化表面特征的高表面积纤维介质
|
WO2016057975A2
(en)
|
2014-10-10 |
2016-04-14 |
Research Institute At Nationwide Children's Hospital |
Guided injections for aav gene transfer to muscle
|
WO2016073739A1
(en)
|
2014-11-05 |
2016-05-12 |
Research Institute At Nationwide Children's Hospital |
Methods and materials for producing recombinant viruses in eukaryotic microalgae
|
SG11201703399QA
(en)
|
2014-12-08 |
2017-05-30 |
Emd Millipore Corp |
Mixed bed ion exchange adsorber
|
SG11201704887SA
(en)
|
2014-12-15 |
2017-07-28 |
Univ Columbia |
Novel tilapia virus and uses thereof
|
MA41451A
(fr)
|
2015-02-04 |
2017-12-12 |
Univ Washington |
Constructions anti-tau
|
BR112017017812A2
(pt)
|
2015-02-23 |
2018-04-10 |
Crispr Therapeutics Ag |
materiais e métodos para tratamento de hemoglobinopatias
|
US10017832B2
(en)
|
2015-08-25 |
2018-07-10 |
Washington University |
Compositions and methods for site specific recombination at asymmetric sites
|
BR112018005177A2
(pt)
|
2015-09-17 |
2018-10-09 |
Res Inst Nationwide Childrens Hospital |
métodos e materiais para terapia com gene galgt2
|
US20190048340A1
(en)
|
2015-09-24 |
2019-02-14 |
Crispr Therapeutics Ag |
Novel family of rna-programmable endonucleases and their uses in genome editing and other applications
|
JP2019507579A
(ja)
|
2015-10-28 |
2019-03-22 |
クリスパー セラピューティクス アーゲー |
デュシェンヌ型筋ジストロフィーの処置のための材料および方法
|
WO2017077386A1
(en)
|
2015-11-06 |
2017-05-11 |
Crispr Therapeutics Ag |
Materials and methods for treatment of glycogen storage disease type 1a
|
SG11201804166YA
(en)
|
2015-11-16 |
2018-06-28 |
Res Inst Nationwide Childrens Hospital |
Materials and methods for treatment of titin-based myopathies and other titinopaties
|
EP3967758A1
(en)
|
2015-12-01 |
2022-03-16 |
CRISPR Therapeutics AG |
Materials and methods for treatment of alpha-1 antitrypsin deficiency
|
EP3394260B1
(en)
|
2015-12-23 |
2021-02-17 |
CRISPR Therapeutics AG |
Materials and methods for treatment of amyotrophic lateral sclerosis and/or frontal temporal lobular degeneration
|
US11938193B2
(en)
|
2016-01-08 |
2024-03-26 |
Washington University |
Compositions comprising chemerin and methods of use thereof
|
EP3411078A1
(en)
|
2016-02-02 |
2018-12-12 |
Crispr Therapeutics AG |
Materials and methods for treatment of severe combined immunodeficiency (scid) or omenn syndrome
|
US20190112353A1
(en)
|
2016-02-18 |
2019-04-18 |
Crispr Therapeutics Ag |
Materials and methods for treatment of severe combined immunodeficiency (scid) or omenn syndrome
|
WO2017147509A1
(en)
|
2016-02-25 |
2017-08-31 |
Marco Colonna |
Compositions comprising trem2 and methods of use thereof
|
AU2017222653B2
(en)
|
2016-02-26 |
2023-06-01 |
Research Institute At Nationwide Children's Hospital |
Recombinant virus products and methods for inducing DUX4 exon skipping
|
WO2017158422A1
(en)
|
2016-03-16 |
2017-09-21 |
Crispr Therapeutics Ag |
Materials and methods for treatment of hereditary haemochromatosis
|
JP7253379B2
(ja)
|
2016-04-02 |
2023-04-06 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
組織特異的発現のための改変u6プロモーターシステム
|
CN109121395B
(zh)
|
2016-04-15 |
2022-08-09 |
全国儿童医院研究所 |
腺相关病毒载体递送β-肌聚糖和微RNA-29以及肌营养不良症的治疗
|
MA45477A
(fr)
|
2016-04-15 |
2019-02-20 |
Res Inst Nationwide Childrens Hospital |
Administration à vecteurs de virus adéno-associé de microarn-29 et micro-dystrophine pour traiter la dystrophie musculaire
|
EP3445388B1
(en)
|
2016-04-18 |
2024-04-17 |
Vertex Pharmaceuticals Incorporated |
Materials and methods for treatment of hemoglobinopathies
|
WO2017191503A1
(en)
|
2016-05-05 |
2017-11-09 |
Crispr Therapeutics Ag |
Materials and methods for treatment of hemoglobinopathies
|
US11427838B2
(en)
|
2016-06-29 |
2022-08-30 |
Vertex Pharmaceuticals Incorporated |
Materials and methods for treatment of myotonic dystrophy type 1 (DM1) and other related disorders
|
WO2018002783A1
(en)
|
2016-06-29 |
2018-01-04 |
Crispr Therapeutics Ag |
Materials and methods for treatment of friedreich ataxia and other related disorders
|
US11174469B2
(en)
|
2016-06-29 |
2021-11-16 |
Crispr Therapeutics Ag |
Materials and methods for treatment of Amyotrophic Lateral Sclerosis (ALS) and other related disorders
|
WO2018007976A1
(en)
|
2016-07-06 |
2018-01-11 |
Crispr Therapeutics Ag |
Materials and methods for treatment of pain related disorders
|
CN109843914B
(zh)
|
2016-07-06 |
2024-03-15 |
沃泰克斯药物股份有限公司 |
用于治疗疼痛相关病症的材料和方法
|
WO2018007871A1
(en)
|
2016-07-08 |
2018-01-11 |
Crispr Therapeutics Ag |
Materials and methods for treatment of transthyretin amyloidosis
|
WO2018020323A2
(en)
|
2016-07-25 |
2018-02-01 |
Crispr Therapeutics Ag |
Materials and methods for treatment of fatty acid disorders
|
US20190194628A1
(en)
*
|
2016-09-01 |
2019-06-27 |
Takeda Vaccines, Inc. |
Methods for producing virus for vaccine production
|
US11583564B2
(en)
|
2016-11-17 |
2023-02-21 |
Nationwide Children's Hospital, Inc. |
Intrathecal delivery of recombinant adeno-associated virus encoding Methyl-CpG binding protein 2
|
CN110191955B
(zh)
|
2016-12-13 |
2024-05-31 |
西雅图儿童医院(Dba西雅图儿童研究所) |
在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法
|
EP3585900B1
(en)
|
2017-02-22 |
2022-12-21 |
CRISPR Therapeutics AG |
Materials and methods for treatment of spinocerebellar ataxia type 2 (sca2) and other spinocerebellar ataxia type 2 protein (atxn2) gene related conditions or disorders
|
US20200040061A1
(en)
|
2017-02-22 |
2020-02-06 |
Crispr Therapeutics Ag |
Materials and methods for treatment of early onset parkinson's disease (park1) and other synuclein, alpha (snca) gene related conditions or disorders
|
JP2020508056A
(ja)
|
2017-02-22 |
2020-03-19 |
クリスパー・セラピューティクス・アクチェンゲゼルシャフトCRISPR Therapeutics AG |
遺伝子編集のための組成物および方法
|
EP3585898A1
(en)
|
2017-02-22 |
2020-01-01 |
CRISPR Therapeutics AG |
Materials and methods for treatment of spinocerebellar ataxia type 1 (sca1) and other spinocerebellar ataxia type 1 protein (atxn1) gene related conditions or disorders
|
EP3585899A1
(en)
|
2017-02-22 |
2020-01-01 |
CRISPR Therapeutics AG |
Materials and methods for treatment of primary hyperoxaluria type 1 (ph1) and other alanine-glyoxylate aminotransferase (agxt) gene related conditions or disorders
|
EP3420076B1
(en)
|
2017-03-06 |
2024-02-21 |
Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. |
Methods of producing and characterizing virus vaccine and virus vaccine composition
|
CN108524929B
(zh)
*
|
2017-03-06 |
2019-05-07 |
广州瑞贝斯药业有限公司 |
一种狂犬病疫苗的生产方法
|
EP4382183A2
(en)
|
2017-03-06 |
2024-06-12 |
Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. |
Methods of producing and characterizing virus vaccine and virus vaccine composition
|
WO2019012336A2
(en)
|
2017-03-17 |
2019-01-17 |
Newcastle University |
ADENO-ASSOCIATED VIRAL VECTOR DELIVERY OF A MICRO-DYSTROPHIN FRAGMENT FOR TREATING MUSCLE DYSTROPHY
|
RS64299B1
(sr)
|
2017-03-17 |
2023-07-31 |
Res Inst Nationwide Childrens Hospital |
Isporuka adeno asociranog virusnog vektora mikrodistrofina specifičnog za mišiće za lečenje mišićne distrofije
|
US20180325955A1
(en)
|
2017-05-12 |
2018-11-15 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
EP3652324A1
(en)
|
2017-07-08 |
2020-05-20 |
Genethon |
Treatment of spinal muscular atrophy
|
BR112020007502A2
(pt)
|
2017-10-17 |
2020-10-06 |
Crispr Therapeutics Ag |
composições e métodos para edição gênica para hemofilia a
|
EP3697915A4
(en)
|
2017-10-18 |
2021-12-08 |
Research Institute at Nationwide Children's Hospital |
ADENO-ASSOCIATED VIRUS VECTOR ADMINISTRATION OF MUSCLE SPECIFIC MICRODYSTROPHIN FOR THE TREATMENT OF MUSCLE DYSTROPHY
|
EP3697916A4
(en)
|
2017-10-20 |
2021-08-11 |
Research Institute at Nationwide Children's Hospital |
METHODS AND MATERIALS FOR NT-3 GENE THERAPY
|
EP3701029A1
(en)
|
2017-10-26 |
2020-09-02 |
Vertex Pharmaceuticals Incorporated |
Materials and methods for treatment of hemoglobinopathies
|
WO2019094253A1
(en)
|
2017-11-08 |
2019-05-16 |
Avexis Inc. |
Means and method for preparing viral vectors and uses of same
|
EP3707256A1
(en)
|
2017-11-09 |
2020-09-16 |
CRISPR Therapeutics AG |
Self-inactivating (sin) crispr/cas or crispr/cpf1 systems and uses thereof
|
EP3714055A1
(en)
|
2017-11-21 |
2020-09-30 |
CRISPR Therapeutics AG |
Materials and methods for treatment of autosomal dominant retinitis pigmentosa
|
JP2021506251A
(ja)
|
2017-12-14 |
2021-02-22 |
クリスパー セラピューティクス アーゲー |
新規rnaプログラム可能エンドヌクレアーゼ系、ならびにゲノム編集および他の適用におけるその使用
|
WO2019123430A1
(en)
|
2017-12-21 |
2019-06-27 |
Casebia Therapeutics Llp |
Materials and methods for treatment of usher syndrome type 2a and/or non-syndromic autosomal recessive retinitis pigmentosa (arrp)
|
EP3728594A1
(en)
|
2017-12-21 |
2020-10-28 |
CRISPR Therapeutics AG |
Materials and methods for treatment of usher syndrome type 2a
|
MA51637A
(fr)
|
2018-01-12 |
2020-11-18 |
Bayer Healthcare Llc |
Compositions et méthodes pour l'édition génique par ciblage de la transferrine
|
MA51788A
(fr)
|
2018-02-05 |
2020-12-16 |
Vertex Pharma |
Substances et méthodes pour traiter des hémoglobinopathies
|
WO2019150196A1
(en)
|
2018-02-05 |
2019-08-08 |
Crispr Therapeutics Ag |
Materials and methods for treatment of hemoglobinopathies
|
EP3752616A1
(en)
|
2018-02-16 |
2020-12-23 |
CRISPR Therapeutics AG |
Compositions and methods for gene editing by targeting fibrinogen-alpha
|
WO2019183150A1
(en)
|
2018-03-19 |
2019-09-26 |
Casebia Therapeutics Limited Liability Partnership |
Novel rna-programmable endonuclease systems and uses thereof
|
WO2019204668A1
(en)
|
2018-04-18 |
2019-10-24 |
Casebia Therapeutics Limited Liability Partnership |
Compositions and methods for knockdown of apo(a) by gene editing for treatment of cardiovascular disease
|
AU2019260687B2
(en)
|
2018-04-27 |
2022-09-22 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Rapamycin resistant cells
|
KR20210018919A
(ko)
|
2018-06-08 |
2021-02-18 |
노파르티스 아게 |
약물 산물 효능을 측정하기 위한 세포-기반 분석
|
GB201809588D0
(en)
|
2018-06-12 |
2018-07-25 |
Univ Bristol |
Materials and methods for modulating intraocular and intracranial pressure
|
AU2019288291A1
(en)
|
2018-06-18 |
2021-01-21 |
Research Institute At Nationwide Children's Hospital |
Recombinant adeno-associated virus products and methods for treating dystroglycanopathies and laminin-deficient muscular dystrophies
|
BR112020025995A2
(pt)
|
2018-06-18 |
2021-03-23 |
Research Institute At Nationwide Children's Hospital |
administração de microdistrofina músculo-específica por vetor de vírus adeno-associado para tratar a distrofia muscular
|
US20210277362A1
(en)
|
2018-06-29 |
2021-09-09 |
Research Institute At Nationwide Children's Hospital |
Recombinant adeno-associated virus products and methods for treating limb girdle muscular dystrophy 2a
|
JP2021534794A
(ja)
|
2018-08-29 |
2021-12-16 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
変異型garsタンパク質の発現を阻害するための生成物および方法
|
WO2020081843A1
(en)
|
2018-10-17 |
2020-04-23 |
Casebia Therapeutics Limited Liability Partnership |
Compositions and methods for delivering transgenes
|
JP2022511776A
(ja)
|
2018-11-30 |
2022-02-01 |
ノバルティス アーゲー |
Aavウイルスベクター及びその使用
|
JP2022516010A
(ja)
|
2018-12-21 |
2022-02-24 |
ジェネトン |
遺伝子療法ベクターのための発現カセット
|
WO2020142479A1
(en)
|
2018-12-31 |
2020-07-09 |
Research Institute At Nationwide Children's Hospital |
Dux4 rna silencing using rna targeting crispr-cas13b
|
TW202043466A
(zh)
|
2019-01-25 |
2020-12-01 |
德商百靈佳殷格翰國際股份有限公司 |
編碼ccl21之重組棒狀病毒
|
JP2022519597A
(ja)
|
2019-02-04 |
2022-03-24 |
リサーチ・インスティチュート・アット・ネーションワイド・チルドレンズ・ホスピタル |
Cln6ポリヌクレオチドのアデノ随伴ウイルス送達
|
BR112021015285A2
(pt)
|
2019-02-04 |
2021-10-05 |
Research Institute At Nationwide Children's Hospital |
Entrega de vírus adenoassociado de polinucleotídeo cln3
|
SG11202108357PA
(en)
|
2019-02-15 |
2021-08-30 |
Crispr Therapeutics Ag |
Gene editing for hemophilia a with improved factor viii expression
|
EP3930765A1
(en)
|
2019-02-26 |
2022-01-05 |
Research Institute at Nationwide Children's Hospital |
Adeno-associated virus vector delivery of b-sarcoglycan and the treatment of muscular dystrophy
|
AU2020239225A1
(en)
|
2019-03-12 |
2021-09-30 |
Bayer Healthcare Llc |
Novel high fidelity RNA-programmable endonuclease systems and uses thereof
|
CA3137080A1
(en)
|
2019-04-15 |
2020-10-22 |
Sanford Research |
Gene therapy for treating or preventing visual effects in batten disease
|
EP3966327A1
(en)
|
2019-05-08 |
2022-03-16 |
Vertex Pharmaceuticals Incorporated |
Crispr/cas all-in-two vector systems for treatment of dmd
|
WO2020236351A1
(en)
|
2019-05-17 |
2020-11-26 |
Research Institute At Nationwide Children's Hospital |
Improved delivery of gene therapy vectors to retinal cells using a glycoside hydrolase enzyme
|
US20200407729A1
(en)
|
2019-06-28 |
2020-12-31 |
Crispr Therapeutics Ag |
Materials and methods for controlling gene editing
|
JP2022541070A
(ja)
|
2019-07-25 |
2022-09-21 |
ノバルティス アーゲー |
調節可能な発現系
|
KR20220092489A
(ko)
|
2019-08-21 |
2022-07-01 |
더 리서치 인스티튜트 앳 네이션와이드 칠드런스 하스피탈 |
알파-사코글리칸의 아데노 관련 바이러스 벡터 전달 및 근위축증 치료
|
CA3158286A1
(en)
|
2019-10-18 |
2021-04-22 |
Research Institute At Nationwide Children's Hospital |
Gene therapy targeting cochlear cells
|
JP2022552014A
(ja)
|
2019-10-18 |
2022-12-14 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
Irf2bpl遺伝子の変異に関連する障害の治療のための材料および方法
|
AU2020385387A1
(en)
|
2019-11-22 |
2022-06-02 |
Fondazione Irccs Ca' Granda Ospedale Maggiore Foliclinico |
Materials and methods for treatment of disorders associated with the IGHMBP2 gene
|
AU2020408225A1
(en)
|
2019-12-20 |
2022-07-14 |
Research Institute At Nationwide Children's Hospital |
Optimized gene therapy for targeting muscle in muscle diseases
|
AU2021224186A1
(en)
|
2020-02-18 |
2022-09-08 |
Research Institute At Nationwide Children's Hospital |
AAV-mediated targeting of mirna in the treatment of X-linked disorders
|
US20230151390A1
(en)
|
2020-04-14 |
2023-05-18 |
Genethon |
Vectors for the treatment of acid ceramidase deficiency
|
BR112022025586A2
(pt)
|
2020-06-15 |
2023-03-07 |
Res Inst Nationwide Childrens Hospital |
Liberação de vetor de vírus adenoassociado para distrofias musculares
|
WO2022018638A1
(en)
|
2020-07-21 |
2022-01-27 |
Crispr Therapeutics Ag |
Genome-editing compositions and methods to modulate faah for treatment of neurological disorders
|
TW202227634A
(zh)
|
2020-09-08 |
2022-07-16 |
美商薩羅塔治療公司 |
表現γ—肌聚醣之腺相關病毒載體之全身性遞送及肌肉失養症之治療
|
AU2021345112A1
(en)
|
2020-09-15 |
2023-04-27 |
Research Institute At Nationwide Children's Hospital |
Aav-mediated homology-independent targeted integration gene editing for correction of diverse dmd mutations in patients with muscular dystrophy
|
CN116590346B
(zh)
*
|
2020-09-15 |
2024-05-14 |
上海药明巨诺生物医药研发有限公司 |
一种慢病毒载体纯化方法
|
JP2023543029A
(ja)
|
2020-09-28 |
2023-10-12 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
筋ジストロフィーの治療のための製品及び方法
|
US20220290136A1
(en)
|
2020-09-30 |
2022-09-15 |
Crispr Therapeutics Ag |
Materials and methods for treatment of amyotrophic lateral sclerosis
|
RU2748475C1
(ru)
*
|
2020-11-02 |
2021-05-26 |
Федеральное государственное бюджетное учреждение "Федеральный центр охраны здоровья животных" (ФГБУ "ВНИИЗЖ") |
Способ спектрометрического определения концентрации рибонуклеопротеина вируса бешенства по оценке количества молекул вирусной РНК в сырье для антирабических вакцин
|
IL303230A
(en)
|
2020-11-30 |
2023-07-01 |
Res Inst Nationwide Childrens Hospital |
Preparations and methods for the treatment of facial-shoulder-arm muscle atrophy
|
EP4263829A1
(en)
|
2020-12-17 |
2023-10-25 |
Vertex Pharmaceuticals Incorporated |
Compositions and methods for editing beta-globin for treatment of hemaglobinopathies
|
WO2022164860A1
(en)
|
2021-01-27 |
2022-08-04 |
Research Institute At Nationwide Children's Hospital |
Materials and methods for the treatment of lysosomal acid lipase deficiency (lal-d)
|
AU2022216260A1
(en)
|
2021-02-03 |
2023-08-17 |
Research Institute At Nationwide Children's Hospital |
Compositions and methods for treating disease associated with dux4 overexpression
|
WO2022170038A1
(en)
|
2021-02-05 |
2022-08-11 |
Amicus Therapeutics, Inc. |
Adeno-associated virus delivery of cln3 polynucleotide
|
AU2022229489A1
(en)
|
2021-03-04 |
2023-08-31 |
Research Institute At Nationwide Children's Hospital |
Products and methods for treatment of dystrophin-based myopathies using crispr-cas9 to correct dmd exon duplications
|
WO2022188797A1
(en)
|
2021-03-09 |
2022-09-15 |
Huigene Therapeutics Co., Ltd. |
Engineered crispr/cas13 system and uses thereof
|
US20240189452A1
(en)
|
2021-04-13 |
2024-06-13 |
Research Institute At Nationwide Children's Hospital |
Recombinant Adeno-Associated Virus Encoding Methyl-CPG Binding Protein 2 for Treating PITT Hopkins Syndrome VIA Intrathecal Delivery
|
US20240200066A1
(en)
|
2021-04-23 |
2024-06-20 |
Research Institute At Nationwide Children's Hospital |
Products and methods for treating muscular dystrophy
|
EP4341413A1
(en)
|
2021-05-17 |
2024-03-27 |
Sarepta Therapeutics, Inc. |
Production of recombinant aav vectors for treating muscular dystrophy
|
EP4108263A3
(en)
|
2021-06-02 |
2023-03-22 |
Research Institute at Nationwide Children's Hospital |
Recombinant adeno-associated virus products and methods for treating limb girdle muscular dystrophy 2a
|
KR20240021218A
(ko)
|
2021-06-11 |
2024-02-16 |
바이엘 악티엔게젤샤프트 |
신규 유형 v rna 프로그래밍가능 엔도뉴클레아제 시스템
|
EP4101928A1
(en)
|
2021-06-11 |
2022-12-14 |
Bayer AG |
Type v rna programmable endonuclease systems
|
WO2023283962A1
(en)
|
2021-07-16 |
2023-01-19 |
Huigene Therapeutics Co., Ltd. |
Modified aav capsid for gene therapy and methods thereof
|
CA3228365A1
(en)
|
2021-08-11 |
2023-02-16 |
Solid Biosciences Inc. |
Treatment of muscular dystrophy
|
EP4144841A1
(en)
|
2021-09-07 |
2023-03-08 |
Bayer AG |
Novel small rna programmable endonuclease systems with impoved pam specificity and uses thereof
|
WO2023042104A1
(en)
|
2021-09-16 |
2023-03-23 |
Novartis Ag |
Novel transcription factors
|
AU2022360382A1
(en)
|
2021-10-07 |
2024-05-09 |
Research Institute At Nationwide Children's Hospital |
Products and methods for myelin protein zero silencing and treating cmt1b disease
|
WO2023060233A1
(en)
|
2021-10-08 |
2023-04-13 |
Amicus Therapeutics, Inc. |
Biomarkers for lysosomal storage diseases
|
EP4219726A1
(en)
|
2021-10-15 |
2023-08-02 |
Research Institute at Nationwide Children's Hospital |
Self-complementary adeno-associated virus vector and its use in treatment of muscular dystrophy
|
JP2023081369A
(ja)
|
2021-11-30 |
2023-06-09 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
自己相補的アデノ随伴ウイルスベクター及び筋ジストロフィーの治療におけるその使用
|
EP4198047A1
(en)
|
2021-12-16 |
2023-06-21 |
Genethon |
Fukutin related protein gene transfer increase using modified itr sequences
|
EP4198134A1
(en)
|
2021-12-16 |
2023-06-21 |
Genethon |
Gamma-sarcoglycan gene transfer increase using modified itr sequences
|
EP4198046A1
(en)
|
2021-12-16 |
2023-06-21 |
Genethon |
Alpha-sarcoglycan gene transfer increase using modified itr sequences
|
EP4198048A1
(en)
|
2021-12-16 |
2023-06-21 |
Genethon |
Calpain-3 gene transfer increase using modified itr sequences
|
WO2023122669A1
(en)
|
2021-12-21 |
2023-06-29 |
Research Institute At Nationwide Children's Hospital |
Materials and methods for the treatment of limb girdle muscular dystrophy
|
WO2023118068A1
(en)
|
2021-12-23 |
2023-06-29 |
Bayer Aktiengesellschaft |
Novel small type v rna programmable endonuclease systems
|
WO2023168400A2
(en)
|
2022-03-03 |
2023-09-07 |
Research Institute At Nationwide Children's Hospital |
Materials and methods for the treatment of eif2b5 mutations and diseases resulting therefrom
|
WO2023196818A1
(en)
|
2022-04-04 |
2023-10-12 |
The Regents Of The University Of California |
Genetic complementation compositions and methods
|
WO2023214346A1
(en)
|
2022-05-06 |
2023-11-09 |
Novartis Ag |
Novel recombinant aav vp2 fusion polypeptides
|
WO2023240177A1
(en)
|
2022-06-08 |
2023-12-14 |
Research Instiitute At Nationwide Children's Hospital |
Products and methods for treating diseases or conditions associated with mutant or pathogenic kcnq3 expression
|
WO2023237587A1
(en)
|
2022-06-10 |
2023-12-14 |
Bayer Aktiengesellschaft |
Novel small type v rna programmable endonuclease systems
|
WO2024011115A1
(en)
|
2022-07-06 |
2024-01-11 |
Research Institute At Nationwide Children's Hospital |
Adeno-associated virus delivery of cln1 polynucleotide
|
WO2024035782A1
(en)
|
2022-08-10 |
2024-02-15 |
Aav Gene Therapeutics, Inc. |
Aav-mediated intramuscular delivery of insulin
|
WO2024081706A1
(en)
|
2022-10-11 |
2024-04-18 |
Research Institute At Nationwide Children's Hospital |
Adeno-associated virus delivery to treat spinal muscular atrophy with respiratory distress type 1 (smard1) and charcot-marie-tooth type 2s (cmt2s)
|
WO2024092126A1
(en)
|
2022-10-27 |
2024-05-02 |
Cargo Therapeutics, Inc. |
Compositions and methods for improved immunotherapies
|
WO2024129743A2
(en)
|
2022-12-13 |
2024-06-20 |
Bluerock Therapeutics Lp |
Engineered type v rna programmable endonucleases and their uses
|