DK0846269T3 - Fremgangsmåde til bestemmelse af aggregationsgraden af beta A4-peptidet - Google Patents

Fremgangsmåde til bestemmelse af aggregationsgraden af beta A4-peptidet

Info

Publication number
DK0846269T3
DK0846269T3 DK96924657T DK96924657T DK0846269T3 DK 0846269 T3 DK0846269 T3 DK 0846269T3 DK 96924657 T DK96924657 T DK 96924657T DK 96924657 T DK96924657 T DK 96924657T DK 0846269 T3 DK0846269 T3 DK 0846269T3
Authority
DK
Denmark
Prior art keywords
aggregation
peptide
beta
determining
degree
Prior art date
Application number
DK96924657T
Other languages
Danish (da)
English (en)
Inventor
Shefali Goyal
Joseph West Paul
Norbert G Riedel
Sudhir R Sahasrabudhe
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK0846269T3 publication Critical patent/DK0846269T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
DK96924657T 1995-08-16 1996-07-23 Fremgangsmåde til bestemmelse af aggregationsgraden af beta A4-peptidet DK0846269T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51560695A 1995-08-16 1995-08-16
PCT/US1996/012034 WO1997007403A1 (en) 1995-08-16 1996-07-23 A METHOD OF DETERMINING THE DEGREE OF AGGREGATION OF THE βA4 PEPTIDE

Publications (1)

Publication Number Publication Date
DK0846269T3 true DK0846269T3 (da) 2003-12-01

Family

ID=24052039

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96924657T DK0846269T3 (da) 1995-08-16 1996-07-23 Fremgangsmåde til bestemmelse af aggregationsgraden af beta A4-peptidet

Country Status (19)

Country Link
EP (1) EP0846269B1 (de)
JP (1) JP3042895B2 (de)
KR (1) KR19990036439A (de)
CN (1) CN1107230C (de)
AR (1) AR003251A1 (de)
AT (1) ATE250766T1 (de)
AU (1) AU697842B2 (de)
CA (1) CA2229187C (de)
DE (1) DE69630131T2 (de)
DK (1) DK0846269T3 (de)
ES (1) ES2206586T3 (de)
HK (1) HK1015030A1 (de)
IL (1) IL122759A (de)
NO (1) NO980623L (de)
NZ (1) NZ313070A (de)
PT (1) PT846269E (de)
TW (1) TW574503B (de)
WO (1) WO1997007403A1 (de)
ZA (1) ZA966808B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516535A (ja) * 2002-09-12 2006-07-06 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニア 異なる配列のタンパク質から形成されたアミロイドに共通する高分子量凝集中間体に対して特異的な免疫原および対応する抗体
WO2015178398A1 (ja) * 2014-05-22 2015-11-26 株式会社 島津製作所 脳内のアミロイドβペプチド蓄積状態を評価するサロゲート・バイオマーカー及びその分析方法
CN104729946A (zh) * 2014-12-18 2015-06-24 江苏大学 一种检测淀粉样多肽聚集及其聚集抑制剂评估的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816416A (en) * 1986-08-27 1989-03-28 Paul Averback Microspheric bodies for use in screening therapies for Azheimer's disease and related conditions
AU7556994A (en) * 1993-08-13 1995-03-14 Molecular Geriatrics Corporation Methods for the diagnosis of alzheimer's disease
US5744368A (en) * 1993-11-04 1998-04-28 Research Foundation Of State University Of New York Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)

Also Published As

Publication number Publication date
HK1015030A1 (en) 1999-10-08
CA2229187A1 (en) 1997-02-27
AR003251A1 (es) 1998-07-08
EP0846269B1 (de) 2003-09-24
DE69630131D1 (de) 2003-10-30
DE69630131T2 (de) 2004-07-08
KR19990036439A (ko) 1999-05-25
AU6505296A (en) 1997-03-12
IL122759A (en) 2003-05-29
NO980623D0 (no) 1998-02-13
CA2229187C (en) 2003-03-18
NZ313070A (en) 1999-01-28
TW574503B (en) 2004-02-01
JPH11501398A (ja) 1999-02-02
IL122759A0 (en) 1998-08-16
MX9801255A (es) 1998-05-31
NO980623L (no) 1998-02-13
JP3042895B2 (ja) 2000-05-22
AU697842B2 (en) 1998-10-15
CN1107230C (zh) 2003-04-30
PT846269E (pt) 2004-01-30
ATE250766T1 (de) 2003-10-15
CN1193385A (zh) 1998-09-16
ZA966808B (en) 1997-02-19
ES2206586T3 (es) 2004-05-16
EP0846269A1 (de) 1998-06-10
WO1997007403A1 (en) 1997-02-27

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