HK1015030A1 - A method of determining the degree of aggregation of the a4 peptide - Google Patents

A method of determining the degree of aggregation of the a4 peptide

Info

Publication number
HK1015030A1
HK1015030A1 HK99100195A HK99100195A HK1015030A1 HK 1015030 A1 HK1015030 A1 HK 1015030A1 HK 99100195 A HK99100195 A HK 99100195A HK 99100195 A HK99100195 A HK 99100195A HK 1015030 A1 HK1015030 A1 HK 1015030A1
Authority
HK
Hong Kong
Prior art keywords
aggregation
peptide
determining
degree
Prior art date
Application number
HK99100195A
Other languages
English (en)
Inventor
Shefali Goyal
Joseph West Paul
Norbert G Riedel
Sudhir R Sahasrabudhe
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of HK1015030A1 publication Critical patent/HK1015030A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
HK99100195A 1995-08-16 1999-01-14 A method of determining the degree of aggregation of the a4 peptide HK1015030A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51560695A 1995-08-16 1995-08-16
PCT/US1996/012034 WO1997007403A1 (en) 1995-08-16 1996-07-23 A METHOD OF DETERMINING THE DEGREE OF AGGREGATION OF THE βA4 PEPTIDE

Publications (1)

Publication Number Publication Date
HK1015030A1 true HK1015030A1 (en) 1999-10-08

Family

ID=24052039

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99100195A HK1015030A1 (en) 1995-08-16 1999-01-14 A method of determining the degree of aggregation of the a4 peptide

Country Status (19)

Country Link
EP (1) EP0846269B1 (de)
JP (1) JP3042895B2 (de)
KR (1) KR19990036439A (de)
CN (1) CN1107230C (de)
AR (1) AR003251A1 (de)
AT (1) ATE250766T1 (de)
AU (1) AU697842B2 (de)
CA (1) CA2229187C (de)
DE (1) DE69630131T2 (de)
DK (1) DK0846269T3 (de)
ES (1) ES2206586T3 (de)
HK (1) HK1015030A1 (de)
IL (1) IL122759A (de)
NO (1) NO980623D0 (de)
NZ (1) NZ313070A (de)
PT (1) PT846269E (de)
TW (1) TW574503B (de)
WO (1) WO1997007403A1 (de)
ZA (1) ZA966808B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003270643A1 (en) * 2002-09-12 2004-04-30 The Regents Of The University Of California Immunogens and corresponding antibodies specific for high molecular weight aggregation intermediates common to amyloids formed from proteins of differing sequence
AU2015262399B9 (en) * 2014-05-22 2021-07-22 National Center For Geriatrics And Gerontology Surrogate biomarker for evaluating intracerebral amyloid beta peptide accumulation and method for analysis thereof
CN104729946A (zh) * 2014-12-18 2015-06-24 江苏大学 一种检测淀粉样多肽聚集及其聚集抑制剂评估的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816416A (en) * 1986-08-27 1989-03-28 Paul Averback Microspheric bodies for use in screening therapies for Azheimer's disease and related conditions
WO1995005604A2 (en) * 1993-08-13 1995-02-23 Molecular Geriatrics Corporation Methods for the diagnosis of alzheimer's disease
US5744368A (en) * 1993-11-04 1998-04-28 Research Foundation Of State University Of New York Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)

Also Published As

Publication number Publication date
IL122759A0 (en) 1998-08-16
ZA966808B (en) 1997-02-19
IL122759A (en) 2003-05-29
AU697842B2 (en) 1998-10-15
KR19990036439A (ko) 1999-05-25
CA2229187A1 (en) 1997-02-27
NZ313070A (en) 1999-01-28
ATE250766T1 (de) 2003-10-15
DK0846269T3 (da) 2003-12-01
EP0846269A1 (de) 1998-06-10
CN1193385A (zh) 1998-09-16
MX9801255A (es) 1998-05-31
NO980623L (no) 1998-02-13
NO980623D0 (no) 1998-02-13
JPH11501398A (ja) 1999-02-02
ES2206586T3 (es) 2004-05-16
TW574503B (en) 2004-02-01
WO1997007403A1 (en) 1997-02-27
DE69630131T2 (de) 2004-07-08
JP3042895B2 (ja) 2000-05-22
CN1107230C (zh) 2003-04-30
CA2229187C (en) 2003-03-18
AU6505296A (en) 1997-03-12
AR003251A1 (es) 1998-07-08
DE69630131D1 (de) 2003-10-30
PT846269E (pt) 2004-01-30
EP0846269B1 (de) 2003-09-24

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070723