ATE250766T1 - Verfahren zur bestimmung des aggregationsgrades des beta a4-peptids - Google Patents

Verfahren zur bestimmung des aggregationsgrades des beta a4-peptids

Info

Publication number
ATE250766T1
ATE250766T1 AT96924657T AT96924657T ATE250766T1 AT E250766 T1 ATE250766 T1 AT E250766T1 AT 96924657 T AT96924657 T AT 96924657T AT 96924657 T AT96924657 T AT 96924657T AT E250766 T1 ATE250766 T1 AT E250766T1
Authority
AT
Austria
Prior art keywords
aggregation
peptide
beta
determining
degree
Prior art date
Application number
AT96924657T
Other languages
English (en)
Inventor
Shefali Goyal
Joseph West Paul
Norbert G Riedel
Sudhir R Sahasrabudhe
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of ATE250766T1 publication Critical patent/ATE250766T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
AT96924657T 1995-08-16 1996-07-23 Verfahren zur bestimmung des aggregationsgrades des beta a4-peptids ATE250766T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51560695A 1995-08-16 1995-08-16
PCT/US1996/012034 WO1997007403A1 (en) 1995-08-16 1996-07-23 A METHOD OF DETERMINING THE DEGREE OF AGGREGATION OF THE βA4 PEPTIDE

Publications (1)

Publication Number Publication Date
ATE250766T1 true ATE250766T1 (de) 2003-10-15

Family

ID=24052039

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96924657T ATE250766T1 (de) 1995-08-16 1996-07-23 Verfahren zur bestimmung des aggregationsgrades des beta a4-peptids

Country Status (19)

Country Link
EP (1) EP0846269B1 (de)
JP (1) JP3042895B2 (de)
KR (1) KR19990036439A (de)
CN (1) CN1107230C (de)
AR (1) AR003251A1 (de)
AT (1) ATE250766T1 (de)
AU (1) AU697842B2 (de)
CA (1) CA2229187C (de)
DE (1) DE69630131T2 (de)
DK (1) DK0846269T3 (de)
ES (1) ES2206586T3 (de)
HK (1) HK1015030A1 (de)
IL (1) IL122759A (de)
NO (1) NO980623D0 (de)
NZ (1) NZ313070A (de)
PT (1) PT846269E (de)
TW (1) TW574503B (de)
WO (1) WO1997007403A1 (de)
ZA (1) ZA966808B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60336848D1 (de) * 2002-09-12 2011-06-01 Univ California Immunogene und entsprechende antikörper, die spezifisch sind für häufige hochmolekulare aggregations-zwischenprodukte von amyloiden aus proteinen unterschiedlicher sequenz
EP3540441A1 (de) * 2014-05-22 2019-09-18 Shimadzu Corporation Surrogatbiomarker zur beurteilung der intrazerebralen amyloid-ss-peptid-akkumulation und verfahren zur analyse davon
CN104729946A (zh) * 2014-12-18 2015-06-24 江苏大学 一种检测淀粉样多肽聚集及其聚集抑制剂评估的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816416A (en) * 1986-08-27 1989-03-28 Paul Averback Microspheric bodies for use in screening therapies for Azheimer's disease and related conditions
WO1995005604A2 (en) * 1993-08-13 1995-02-23 Molecular Geriatrics Corporation Methods for the diagnosis of alzheimer's disease
US5744368A (en) * 1993-11-04 1998-04-28 Research Foundation Of State University Of New York Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)

Also Published As

Publication number Publication date
CN1107230C (zh) 2003-04-30
IL122759A (en) 2003-05-29
DK0846269T3 (da) 2003-12-01
JPH11501398A (ja) 1999-02-02
AU697842B2 (en) 1998-10-15
MX9801255A (es) 1998-05-31
NO980623L (no) 1998-02-13
EP0846269A1 (de) 1998-06-10
AU6505296A (en) 1997-03-12
ZA966808B (en) 1997-02-19
CN1193385A (zh) 1998-09-16
JP3042895B2 (ja) 2000-05-22
CA2229187C (en) 2003-03-18
NO980623D0 (no) 1998-02-13
IL122759A0 (en) 1998-08-16
KR19990036439A (ko) 1999-05-25
TW574503B (en) 2004-02-01
CA2229187A1 (en) 1997-02-27
ES2206586T3 (es) 2004-05-16
EP0846269B1 (de) 2003-09-24
WO1997007403A1 (en) 1997-02-27
DE69630131T2 (de) 2004-07-08
NZ313070A (en) 1999-01-28
HK1015030A1 (en) 1999-10-08
AR003251A1 (es) 1998-07-08
DE69630131D1 (de) 2003-10-30
PT846269E (pt) 2004-01-30

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