DE69735926D1 - Interleukin-18 Rezeptorproteine - Google Patents

Interleukin-18 Rezeptorproteine

Info

Publication number
DE69735926D1
DE69735926D1 DE69735926T DE69735926T DE69735926D1 DE 69735926 D1 DE69735926 D1 DE 69735926D1 DE 69735926 T DE69735926 T DE 69735926T DE 69735926 T DE69735926 T DE 69735926T DE 69735926 D1 DE69735926 D1 DE 69735926D1
Authority
DE
Germany
Prior art keywords
interleukin
receptor proteins
receptor
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69735926T
Other languages
English (en)
Inventor
Kakuji Torigoe
Shimpei Ushio
Toshio Kunikata
Masashi Kurimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Application granted granted Critical
Publication of DE69735926D1 publication Critical patent/DE69735926D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69735926T 1996-12-26 1997-12-23 Interleukin-18 Rezeptorproteine Expired - Lifetime DE69735926D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP35642696 1996-12-26
JP5252697 1997-02-21
JP16349097 1997-06-06
JP21549097 1997-07-28

Publications (1)

Publication Number Publication Date
DE69735926D1 true DE69735926D1 (de) 2006-06-29

Family

ID=27462786

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735926T Expired - Lifetime DE69735926D1 (de) 1996-12-26 1997-12-23 Interleukin-18 Rezeptorproteine

Country Status (7)

Country Link
US (2) US7141393B2 (de)
EP (1) EP0850952B1 (de)
KR (1) KR100439289B1 (de)
AU (1) AU736274B2 (de)
CA (1) CA2219963C (de)
DE (1) DE69735926D1 (de)
TW (1) TWI224108B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393663B2 (en) 1997-08-01 2008-07-01 Serono Genetics Institute S.A. Expressed sequence tags and encoded human proteins
US7220717B2 (en) 1997-08-14 2007-05-22 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use
IL121860A0 (en) 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
US7704944B2 (en) * 1997-08-14 2010-04-27 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
CA2318482C (en) 1998-01-23 2010-04-13 Immunex Corporation Il-18 receptors
CA2276216A1 (en) * 1998-06-24 1999-12-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo An artificial peptide capable of neutralizing the biological activity of interleukin-18
IL131047A0 (en) * 1999-07-22 2001-01-28 Yeda Res & Dev Use of il-18 inhibitors
DE60041432D1 (de) * 1999-11-16 2009-03-12 Hayashibara Biochem Lab Antikörper spezifisch für den Interleukin-18 Vorläufer
NZ520392A (en) * 2000-02-10 2005-04-29 Abbott Lab Antibodies that bind human interleukin-18 and methods of making and using
KR20020086540A (ko) * 2000-02-21 2002-11-18 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. Ｉｌ-18 저해물질의 용도
AU2002224417A1 (en) * 2000-10-18 2002-04-29 Immunex Corporation Methods for treating il-18 mediated disorders
CA2451955C (en) 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
JP2006517191A (ja) 2002-12-30 2006-07-20 アムジエン・インコーポレーテツド 共刺激因子を用いた併用療法
GB2401040A (en) * 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
US20050100965A1 (en) 2003-11-12 2005-05-12 Tariq Ghayur IL-18 binding proteins
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
AU2011226823B2 (en) * 2004-07-16 2012-09-20 Atsuo Sekiyama IL-18 receptor antagonist and pharmaceutical composition containing the antagonist
JP5595632B2 (ja) 2004-07-16 2014-09-24 敦生 関山 Ｉｌ−１８レセプターアンタゴニスト、および当該アンタゴニストを含む薬学的組成物
US7141382B1 (en) 2004-10-12 2006-11-28 Parikh Chirag R Methods for detection of IL-18 as an early marker for diagnosis of acute renal failure and predictor of mortality
JP2009531295A (ja) * 2006-02-22 2009-09-03 ユニバーシティ オブ チューリッヒ 自己免疫疾患又は脱髄疾患を処置するための方法
WO2007117577A2 (en) 2006-04-07 2007-10-18 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human il-18 receptor
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
EA201000903A1 (ru) * 2007-11-30 2011-02-28 Калобиос Фармасьютикалс, Инк. Антитела к pcrv-антигену pseudomonas aeruginosa
KR101790647B1 (ko) 2009-06-10 2017-10-26 스티븐 사니그 리서치 인스티튜트 리미티드 표현형적 유연성을 나타내는 세포 제조 방법
US8945895B2 (en) * 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
TW201215405A (en) 2010-08-25 2012-04-16 Hoffmann La Roche Antibodies against IL-18R1 and uses thereof
WO2013119419A1 (en) * 2012-02-08 2013-08-15 North Carolina State University Treatment of allergic diseases with recombinant antibodies
JOP20200308A1 (ar) 2012-09-07 2017-06-16 Novartis Ag جزيئات إرتباط il-18
JP7127859B2 (ja) 2016-11-09 2022-08-30 ノース カロライナ ステート ユニバーシティ キメラタンパク質を用いたアレルギー疾患の治療
EP3810656A4 (de) * 2018-06-19 2022-04-13 Shanghaitech University Menschliche antikörper gegen menschliches interleukin 18 rezeptor alpha und beta
CN117177999A (zh) * 2022-01-14 2023-12-05 和径医药科技（上海）有限公司 一种靶向IL-18Rβ的抗体及其应用
WO2023133842A1 (zh) * 2022-01-14 2023-07-20 和径医药科技（上海）有限公司 一种靶向IL-18Rβ的抗体及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
IT1254359B (it) * 1992-05-11 1995-09-14 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti il-6
EP0692536B1 (de) 1994-07-14 2000-11-22 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
JP3109018B2 (ja) 1994-07-14 2000-11-13 株式会社林原生物化学研究所 インターフェロン−γの産生を誘導する蛋白質
TW581771B (en) 1994-11-15 2004-04-01 Hayashibara Biochem Lab Recombinant production of a polypeptide for inducing interferon-gamma production, and monoclonal antibody against the polypeptide
JP2724987B2 (ja) 1994-11-15 1998-03-09 株式会社林原生物化学研究所 インターフェロン−γの産生を誘導するポリペプチド
JP3071373B2 (ja) 1994-11-24 2000-07-31 日本鋼管株式会社 ジルコニア薄膜の製造方法
US5776731A (en) 1996-02-21 1998-07-07 Immunex Corporation DNA encoding type-I interleukin-I receptor-like protein designated 2F1

Also Published As

Publication number Publication date
KR19980064719A (ko) 1998-10-07
US7141393B2 (en) 2006-11-28
EP0850952B1 (de) 2006-05-24
KR100439289B1 (ko) 2004-09-10
EP0850952A1 (de) 1998-07-01
TWI224108B (en) 2004-11-21
US20030190318A1 (en) 2003-10-09
US6600022B1 (en) 2003-07-29
CA2219963A1 (en) 1998-06-26
AU4922497A (en) 1998-07-02
CA2219963C (en) 2009-11-10
AU736274B2 (en) 2001-07-26

Similar Documents

Publication Publication Date Title
DE69735926D1 (de) Interleukin-18 Rezeptorproteine
NO2010013I2 (no) Rekombinant FSH-CTP
NO983364L (no) Konsensusproteiner
IS5375A (is) KAY-nýstárlegt ónæmisprótín
DE69734005D1 (de) Gelenkmechanismus
DE59706073D1 (de) Verstellvorrichtung
DE69718276D1 (de) Fixiergerät
NO985680D0 (no) Peptidderivater
NO976058L (no) Rekombinant mistellectin
BR9610239A (pt) Proteínas de fusão-alérgeno-xcd32
NO983849L (no) Peptidderivater
DE69705048D1 (de) Polyimid-mischungen
BR9609671A (pt) Amino uracilas substituídas
DE69702724T2 (de) Vibrator
DE69721912D1 (de) Anschlusselement
TR199701666A3 (tr) Sismanliga karsi proteinler
DK0950063T3 (da) Flergrenede peptidkonstruktioner
DE69941406D1 (de) IL-6 Rezeptor IL-6-gekoppeltes Fusionsprotein
DE69615850D1 (de) G-protein-gekoppelter rezeptor hnfd578
FR2743915B1 (fr) Ardoise communiquante
DE29613006U1 (de) Rollbalg
DE29704960U1 (de) Einstellvorrichtung
BR9510060A (pt) Receptor
DE69739606D1 (de) Ichten verbindungsstellen
DE29622890U1 (de) Schwingelement

Legal Events

Date Code Title Description
8332 No legal effect for de