DK0833938T3 - Reduktion af ketongrupper - Google Patents

Reduktion af ketongrupper

Info

Publication number
DK0833938T3
DK0833938T3 DK96920921T DK96920921T DK0833938T3 DK 0833938 T3 DK0833938 T3 DK 0833938T3 DK 96920921 T DK96920921 T DK 96920921T DK 96920921 T DK96920921 T DK 96920921T DK 0833938 T3 DK0833938 T3 DK 0833938T3
Authority
DK
Denmark
Prior art keywords
pct
compound
formula
produced
reduction
Prior art date
Application number
DK96920921T
Other languages
Danish (da)
English (en)
Inventor
Christopher David Reeve
Original Assignee
Avecia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Ltd filed Critical Avecia Ltd
Application granted granted Critical
Publication of DK0833938T3 publication Critical patent/DK0833938T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
DK96920921T 1995-06-23 1996-06-17 Reduktion af ketongrupper DK0833938T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9512837.7A GB9512837D0 (en) 1995-06-23 1995-06-23 reduction of ketone groups
PCT/GB1996/001422 WO1997000968A1 (en) 1995-06-23 1996-06-17 Reduction of ketone groups

Publications (1)

Publication Number Publication Date
DK0833938T3 true DK0833938T3 (da) 2003-07-14

Family

ID=10776577

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96920921T DK0833938T3 (da) 1995-06-23 1996-06-17 Reduktion af ketongrupper

Country Status (12)

Country Link
US (1) US6001615A (cs)
EP (1) EP0833938B1 (cs)
JP (1) JP3580825B2 (cs)
AT (1) ATE234935T1 (cs)
AU (1) AU6230696A (cs)
CA (1) CA2221800C (cs)
CZ (1) CZ291886B6 (cs)
DE (1) DE69626820T2 (cs)
DK (1) DK0833938T3 (cs)
ES (1) ES2194995T3 (cs)
GB (1) GB9512837D0 (cs)
WO (1) WO1997000968A1 (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69910562T2 (de) * 1998-04-30 2004-06-17 Kaneka Corp. Verfahren zur herstellung von derivaten der 6-cyanomethyl-1,3-dioxan-4-essigsäure
PT1619191E (pt) * 1998-08-05 2010-12-21 Kaneka Corp Processo de produção de derivados opticamente activos do ácido 2-[6-(hidroximetil)-1,3-dioxan-4-il]acético
DE19857302C2 (de) 1998-12-14 2000-10-26 Forschungszentrum Juelich Gmbh Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester
DE19937825B4 (de) * 1999-07-09 2005-08-11 Forschungszentrum Jülich GmbH Verfahren zur Reduktion von Hydroxyketo-Carbonsäuren und deren Estern
EP1194582A1 (de) 1999-07-09 2002-04-10 Forschungszentrum Jülich Gmbh Verfahren zur reduktion von keto-carbonsäuren und deren estern
CZ20012792A3 (cs) * 1999-12-03 2002-03-13 Kaneka Corporation Polypeptid, polynukleotid kódující polypeptid, expresní vektor, transformant a způsob přípravy
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
TWI322829B (cs) 2001-02-02 2010-04-01 Mitsubishi Chem Corp
KR100451413B1 (ko) * 2001-12-28 2004-10-06 한국과학기술연구원 클루이베로마이시스 마르시아누스의 카르보닐 환원효소를이용한 카르보닐 화합물의 환원반응
EP1537222B1 (en) * 2002-08-09 2011-03-09 Codexis, Inc. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
BRPI0413501A (pt) 2003-08-11 2006-10-10 Codexis Inc polipetìdeo, polinucleotìdeo isolado ou recombinante, vetor de expressão, célula hospedeira, e, método de preparar um polipetìdeo de hhdh
EP1654354A1 (en) * 2003-08-11 2006-05-10 Codexis, Inc. Improved ketoreductase polypeptides and related polynucleotides
MXPA06001719A (es) * 2003-08-11 2006-05-19 Codexis Inc Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados.
JP2007502111A (ja) * 2003-08-11 2007-02-08 コデクシス， インコーポレイテッド ４−置換３−ヒドロキシ酪酸誘導体およびビシナルなシアノ，ヒドロキシ置換カルボン酸エステルの生成のための酵素的プロセス
US7588928B2 (en) * 2003-08-11 2009-09-15 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
US7541171B2 (en) * 2003-08-11 2009-06-02 Codexis, Inc. Halohydrin dehalogenases and related polynucleotides
AT503017B1 (de) 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
DE102006010994A1 (de) * 2006-03-09 2007-09-13 Wacker Chemie Ag Verfahren zur enzymatischen Herstellung von chiralen Alkoholen
CN101528917B (zh) * 2006-10-02 2015-07-29 科德克希思公司 用于制备立体异构纯的他汀类及其合成中间体的组合物和方法
WO2008059366A2 (en) * 2006-11-17 2008-05-22 Pfizer Products Inc. Process for the preparation of cis-1, 3-diols from the corresponding beta-hydroxy ketones employing microbial ketone reductases
JP5973131B2 (ja) 2007-09-13 2016-08-23 コデクシス， インコーポレイテッド アセトフェノンの還元のためのケトレダクターゼポリペプチド
SG172231A1 (en) 2008-12-18 2011-07-28 Codexis Inc Recombinant halohydrin dehalogenase polypeptides
US9012189B2 (en) 2010-02-12 2015-04-21 Gevo, Inc. Modified alcohol dehydrogenases for the production of fuels and chemicals
CN102676596A (zh) * 2011-03-16 2012-09-19 苏州国镝医药科技有限公司 生物酶手性合成立普妥中间体ats-7

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3724197A1 (de) * 1987-07-22 1989-02-02 Merck Patent Gmbh Verfahren zur reduktion von ketonen
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5155251A (en) * 1991-10-11 1992-10-13 Warner-Lambert Company Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters

Also Published As

Publication number Publication date
DE69626820T2 (de) 2004-02-12
EP0833938B1 (en) 2003-03-19
ES2194995T3 (es) 2003-12-01
JP3580825B2 (ja) 2004-10-27
DE69626820D1 (de) 2003-04-24
ATE234935T1 (de) 2003-04-15
US6001615A (en) 1999-12-14
EP0833938A1 (en) 1998-04-08
WO1997000968A1 (en) 1997-01-09
CA2221800A1 (en) 1997-01-09
JPH11507204A (ja) 1999-06-29
AU6230696A (en) 1997-01-22
CZ291886B6 (cs) 2003-06-18
CA2221800C (en) 2008-10-28
GB9512837D0 (en) 1995-08-23
CZ412997A3 (cs) 1998-03-18

Similar Documents

Publication Publication Date Title
DK0833938T3 (da) Reduktion af ketongrupper
DK0931083T3 (da) Fremgangsmåde til fremstilling af ecteinascidinforbindelser
DK1040108T3 (da) Orthoanthranilamidderivater som antikoagulanter
DE59108707D1 (de) Verfahren zur Herstellung von Oxetanonen
DE69434696D1 (de) Verfahren zur Herstellung von Verbindungen geeignet als Zwischenprodukte
DE69132318T2 (de) Verfahren zur herstellung von pyrimidinverbindungen
ATE361364T1 (de) Antikörper gegen die ed-b domäne von fibronektin, ihre herstellung und verwendungen
DK0923568T5 (da) Hidtil ukendte benzofuran-4-carboxamider
AU8979291A (en) 2-(2,4,5-substituted phenyl)hydantoin compounds
ATE255582T1 (de) Verfahren zur synthese von 4-und/oder 5-(di) substituierten 2-aminoimidazolen aus 2- aminoimidazolen und aldehyden
BR9612216A (pt) Processo para preparar um composto derivado de piperidina, regioisómero, processo para preparar um regioisómero, derivado de alfa, alfa- di-substituído, e alfa,alfa-di não substituído metilbenzeno, derivado de oxobutila, precursor de derivado de piperidina e processo para tratar reações alérgicas em um paciente.
DK0874841T3 (da) 1-Benzensulfonylpyrrolidin-derivater som antagonister af bradykinin-receptoren
DE69706382T2 (de) Verfahren zur herstellung von 2,2'-bipyrrolyl-pyrromethen-derivaten (prodigiosine)
DE59910677D1 (de) Verfahren sowie neue zwischenprodukte zur herstellung von isoxazolin-3-yl-acylbenzolen
DE69631058D1 (de) Piperindinverbindungen als calcium-kanal-blocker
DE69524578T2 (de) Verfahren zur herstellung von epoxiden
DE69604050T2 (de) Verfahren zur herstellung von 2-(substituierten benzoyl)-1,3 cyclohexanedionen
ATE277898T1 (de) Verfahren zu herstellung von taxol
ATE250042T1 (de) Verfahren zur herstellung von cyclen
ATE322481T1 (de) Zwischenverbindung zur herstellung von carvedilol
DE69828907D1 (de) Synthese von 11-aryl-5,6-dihydro-11h-dibenz(b,e)azepinen
DK1274688T3 (da) Syntese af mellemprodukter, der er nyttige ved fremstilling af tricykliske forbindelser
DE69620244D1 (de) Verfahren zur herstellung von prostaglandin e1
DE69803618D1 (de) Verfahren zur Herstellung von 1,7-Diaryl- oder 1,7-Diheteroarylheptan-4-olen und Synthesezwischenprodukte
TW200611691A (en) Retroviral protease inhibiting compounds