DK0810878T3 - RNA-fotospaltning ved anvendelse af texaphyriner - Google Patents
RNA-fotospaltning ved anvendelse af texaphyrinerInfo
- Publication number
- DK0810878T3 DK0810878T3 DK96919188T DK96919188T DK0810878T3 DK 0810878 T3 DK0810878 T3 DK 0810878T3 DK 96919188 T DK96919188 T DK 96919188T DK 96919188 T DK96919188 T DK 96919188T DK 0810878 T3 DK0810878 T3 DK 0810878T3
- Authority
- DK
- Denmark
- Prior art keywords
- texaphyrin
- cleavage
- rna
- site
- polymer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0042—Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/484,551 US5714328A (en) | 1995-06-07 | 1995-06-07 | RNA photocleavage using texaphyrins |
PCT/US1996/009419 WO1996040253A2 (en) | 1995-06-07 | 1996-05-31 | Rna photocleavage using texaphyrins |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0810878T3 true DK0810878T3 (da) | 1999-10-11 |
Family
ID=23924628
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96919188T DK0810878T3 (da) | 1995-06-07 | 1996-05-31 | RNA-fotospaltning ved anvendelse af texaphyriner |
Country Status (14)
Country | Link |
---|---|
US (1) | US5714328A (da) |
EP (1) | EP0810878B1 (da) |
JP (2) | JPH10510844A (da) |
KR (1) | KR100355251B1 (da) |
AT (1) | ATE177951T1 (da) |
AU (1) | AU694051B2 (da) |
CA (1) | CA2218477C (da) |
DE (1) | DE69601865T2 (da) |
DK (1) | DK0810878T3 (da) |
ES (1) | ES2130826T3 (da) |
GR (1) | GR3030257T3 (da) |
NO (1) | NO975312L (da) |
NZ (1) | NZ310739A (da) |
WO (1) | WO1996040253A2 (da) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US5969111A (en) * | 1994-04-14 | 1999-10-19 | Board Of Regents, The University Of Texas System | Texaphyrins substituted with imidazole are provided |
KR19990067080A (ko) | 1995-10-27 | 1999-08-16 | 엘리엇 알. 램버그 | 특정 뉴클레오티드 서열의 검출방법 및 조성물 |
US5776925A (en) * | 1996-01-25 | 1998-07-07 | Pharmacyclics, Inc. | Methods for cancer chemosensitization |
US6022959A (en) * | 1996-08-20 | 2000-02-08 | Pharmacyclics, Inc. | Nucleic acids internally-derivatized with a texaphyrin metal complex and uses thereof |
AU5237798A (en) * | 1997-05-14 | 1998-12-08 | Sergy Mykolaiovytch Khrapunov | Method for treatment of deoxyribonucleic acid sequence by restrictase |
US6022526A (en) * | 1997-07-30 | 2000-02-08 | Pharmacyclics, Inc. | Use of texaphyrins in detection of melanin and melanin metabolites diagnostic of melanotic melanoma |
US6277337B1 (en) | 1998-07-21 | 2001-08-21 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
US7498156B2 (en) * | 1998-07-21 | 2009-03-03 | Caridianbct Biotechnologies, Llc | Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components |
US20070099170A1 (en) * | 1998-07-21 | 2007-05-03 | Navigant Biotechnologies, Inc. | Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate |
US7049110B2 (en) * | 1998-07-21 | 2006-05-23 | Gambro, Inc. | Inactivation of West Nile virus and malaria using photosensitizers |
US6258577B1 (en) | 1998-07-21 | 2001-07-10 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers |
JP4207258B2 (ja) | 1998-08-31 | 2009-01-14 | 東ソー株式会社 | 特定核酸配列の切断方法 |
US6284220B1 (en) | 1999-06-03 | 2001-09-04 | The General Hospital Corporation | Noninvasive imaging of nucleic acid vectors |
US7220747B2 (en) * | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
US6268120B1 (en) | 1999-10-19 | 2001-07-31 | Gambro, Inc. | Isoalloxazine derivatives to neutralize biological contaminants |
US7648699B2 (en) * | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
TW590780B (en) * | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7985588B2 (en) * | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
US6843961B2 (en) * | 2000-06-15 | 2005-01-18 | Gambro, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
US6638924B2 (en) | 2000-08-30 | 2003-10-28 | Pharmacyclics, Inc. | Metallotexaphyrin derivatives |
US7112671B2 (en) * | 2000-08-30 | 2006-09-26 | Pharmacyclics, Inc. | Non-symmetric tripyrranes in the synthesis of novel macrocycles |
US7449454B2 (en) * | 2000-08-30 | 2008-11-11 | Pharmacyclics, Inc. | Metallotexaphyrin derivatives |
DE10162176B4 (de) * | 2000-12-13 | 2006-03-23 | Institut für Physikalische Hochtechnologie e.V. | Verfahren zum simultanen positionsspezifischen Schneiden von DNA |
US20030228564A1 (en) * | 2001-05-30 | 2003-12-11 | Edrich Richard Alan | Nitric oxide in a pathogen inactivation process |
US6984734B2 (en) | 2002-02-26 | 2006-01-10 | Board Of Regents, The University Of Texas System | Cyclo[n]pyrroles and methods thereto |
US6723750B2 (en) | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
JP2006224318A (ja) * | 2005-02-15 | 2006-08-31 | Brother Ind Ltd | インクジェット記録装置 |
US20070072838A1 (en) * | 2005-09-26 | 2007-03-29 | Pharmacyclics, Inc. | High-purity texaphyrin metal complexes |
US20070078119A1 (en) * | 2005-09-30 | 2007-04-05 | Pharmacyclics, Inc. | Storage system for texaphyrin pharmaceutical formulations |
US8133474B2 (en) * | 2006-09-15 | 2012-03-13 | Massachusetts Institute Of Technology | Sensors for fluorescence and magnetic resonance imaging |
US20140127077A1 (en) | 2012-11-05 | 2014-05-08 | Gail Rock | Device and method for sterilization of instruments and surfaces |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4318825A (en) * | 1979-08-15 | 1982-03-09 | Frame Robert R | Catalytic composite, and method of manufacture |
US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
US4613322A (en) * | 1982-12-08 | 1986-09-23 | Edelson Richard Leslie | Method and system for externally treating the blood |
FR2540122B1 (fr) * | 1983-01-27 | 1985-11-29 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application |
JPS61275228A (ja) * | 1985-03-14 | 1986-12-05 | バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド | 治療用タンパク組成物中のビ−ルスの光動的不活性化 |
US4977177A (en) * | 1985-04-30 | 1990-12-11 | Nippon Petrochemicals Company, Ltd. | Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents |
US4899755A (en) * | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
US4880008A (en) * | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
FR2586704B1 (fr) * | 1985-09-04 | 1987-12-18 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation et a un groupe chimique activable, leur synthese et leurs applications a titre de nucleases artificielles specifiques de sequences. centre national de la recherche scientifique (cnrs) |
CA1315780C (en) * | 1986-01-17 | 1993-04-06 | Yozo Fukuda | Porphyrin derivatives |
US5242797A (en) * | 1986-03-21 | 1993-09-07 | Myron J. Block | Nucleic acid assay method |
US4915683A (en) * | 1986-11-21 | 1990-04-10 | The Medical College Of Wisconsin, Inc. | Antiviral method, agents and apparatus |
US5135717A (en) * | 1986-12-24 | 1992-08-04 | British Technology Group Usa Inc. | Tetrabenztriazaporphyrin reagents and kits containing the same |
US4883790A (en) * | 1987-01-20 | 1989-11-28 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US4878891A (en) * | 1987-06-25 | 1989-11-07 | Baylor Research Foundation | Method for eradicating infectious biological contaminants in body tissues |
EP0396651A4 (en) * | 1988-07-28 | 1990-12-12 | Best Industries, Inc. | Device and method for encapsulating radioactive materials |
AU642396B2 (en) * | 1988-09-08 | 1993-10-21 | British Technology Group Usa, Inc. | Red-shifted phthalocyanine and tetrabenztriazaporphyrin reagents |
US5252720A (en) * | 1989-03-06 | 1993-10-12 | Board Of Regents, The University Of Texas System | Metal complexes of water soluble texaphyrins |
US5041078A (en) * | 1989-03-06 | 1991-08-20 | Baylor Research Foundation, A Nonprofit Corporation Of The State Of Texas | Photodynamic viral deactivation with sapphyrins |
US4935498A (en) * | 1989-03-06 | 1990-06-19 | Board Of Regents, The University Of Texas System | Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
US5256399A (en) * | 1989-03-06 | 1993-10-26 | Board Of Regents, The University Of Texas System | Aromatic pentadentate expanded porphyrins in magnetic resonance imaging |
US5162509A (en) * | 1989-03-06 | 1992-11-10 | Board Of Regents, The University Of Texas System | Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles |
US5272142A (en) * | 1989-03-06 | 1993-12-21 | Board Of Regents, The University Of Texas System | Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles and methods for treating tumors |
US5599923A (en) * | 1989-03-06 | 1997-02-04 | Board Of Regents, University Of Tx | Texaphyrin metal complexes having improved functionalization |
US5559207A (en) * | 1989-03-06 | 1996-09-24 | Board Of Regents, University Of Texas | Texaphyrin metal complex mediated ester hydrolysis |
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US4959363A (en) * | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
FR2650761B1 (fr) * | 1989-08-10 | 1994-03-04 | Elf Aquitaine Ste Nale | Catalyseur d'oxydation a base de metalloporphyrine sur support |
US5219732A (en) * | 1989-09-05 | 1993-06-15 | The Regents Of The University Of California | Antibody-mediated cofactor-driven reactions |
US5457195A (en) * | 1989-12-21 | 1995-10-10 | Board Of Regents, The University Of Texas System | Sapphyrin derivatives and conjugates |
US5159065A (en) * | 1989-12-21 | 1992-10-27 | Board Of Regents, The University Of Texas System | Sapphyrins, derivatives and syntheses |
CA2083048A1 (en) * | 1990-06-14 | 1991-12-15 | James K. Bashkin | Rna hydrolysis/cleavage |
US5272056A (en) * | 1991-01-03 | 1993-12-21 | The Research Foundation Of State University Of New York | Modification of DNA and oligonucleotides using metal complexes of polyaza ligands |
US5607924A (en) * | 1992-01-21 | 1997-03-04 | Pharmacyclics, Inc. | DNA photocleavage using texaphyrins |
US5371199B1 (en) * | 1992-08-14 | 1995-12-26 | Univ Pennsylvania | Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor |
FR2697254A1 (fr) * | 1992-10-22 | 1994-04-29 | Genset Sa | Conjugués constitués par un oligonucléotide lié à des dérivés de métalloporphyrine cationique, leur préparation et leur utilisation. |
EP0758250A1 (en) * | 1994-04-28 | 1997-02-19 | The Board Of Regents, The University Of Texas System | Texaphyrin solid-supports and devices |
EP0778845A1 (de) * | 1994-09-02 | 1997-06-18 | Novartis AG | Oligonukleotidkonjugate, zusammensetzungen und verfahren zur spaltung von ribonukleinsäuren |
-
1995
- 1995-06-07 US US08/484,551 patent/US5714328A/en not_active Expired - Fee Related
-
1996
- 1996-05-31 ES ES96919188T patent/ES2130826T3/es not_active Expired - Lifetime
- 1996-05-31 NZ NZ310739A patent/NZ310739A/xx unknown
- 1996-05-31 DE DE69601865T patent/DE69601865T2/de not_active Expired - Fee Related
- 1996-05-31 CA CA002218477A patent/CA2218477C/en not_active Expired - Fee Related
- 1996-05-31 DK DK96919188T patent/DK0810878T3/da active
- 1996-05-31 WO PCT/US1996/009419 patent/WO1996040253A2/en not_active Application Discontinuation
- 1996-05-31 KR KR1019970704863A patent/KR100355251B1/ko not_active IP Right Cessation
- 1996-05-31 JP JP9501740A patent/JPH10510844A/ja active Pending
- 1996-05-31 AT AT96919188T patent/ATE177951T1/de not_active IP Right Cessation
- 1996-05-31 EP EP96919188A patent/EP0810878B1/en not_active Expired - Lifetime
- 1996-05-31 AU AU61590/96A patent/AU694051B2/en not_active Ceased
-
1997
- 1997-11-19 NO NO975312A patent/NO975312L/no unknown
-
1999
- 1999-05-19 GR GR990401350T patent/GR3030257T3/el unknown
-
2001
- 2001-03-13 JP JP2001071295A patent/JP2001316270A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
NZ310739A (en) | 2000-09-29 |
AU694051B2 (en) | 1998-07-09 |
JPH10510844A (ja) | 1998-10-20 |
ATE177951T1 (de) | 1999-04-15 |
KR100355251B1 (ko) | 2003-02-17 |
DE69601865D1 (de) | 1999-04-29 |
CA2218477C (en) | 2002-10-22 |
DE69601865T2 (de) | 1999-08-05 |
GR3030257T3 (en) | 1999-08-31 |
US5714328A (en) | 1998-02-03 |
NO975312D0 (no) | 1997-11-19 |
CA2218477A1 (en) | 1996-12-19 |
AU6159096A (en) | 1996-12-30 |
WO1996040253A3 (en) | 1997-01-23 |
ES2130826T3 (es) | 1999-07-01 |
JP2001316270A (ja) | 2001-11-13 |
KR19980701473A (ko) | 1998-05-15 |
EP0810878A2 (en) | 1997-12-10 |
WO1996040253A2 (en) | 1996-12-19 |
NO975312L (no) | 1998-02-05 |
EP0810878B1 (en) | 1999-03-24 |
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