DK0796616T3 - Mikrosmådråbeformuleringer med propofol - Google Patents

Mikrosmådråbeformuleringer med propofol

Info

Publication number
DK0796616T3
DK0796616T3 DK97301839T DK97301839T DK0796616T3 DK 0796616 T3 DK0796616 T3 DK 0796616T3 DK 97301839 T DK97301839 T DK 97301839T DK 97301839 T DK97301839 T DK 97301839T DK 0796616 T3 DK0796616 T3 DK 0796616T3
Authority
DK
Denmark
Prior art keywords
propofol
micro
pml
devoid
surrounded
Prior art date
Application number
DK97301839T
Other languages
English (en)
Inventor
Duncan Haynes
Original Assignee
Res Triangle Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24469788&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0796616(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Res Triangle Pharm Ltd filed Critical Res Triangle Pharm Ltd
Application granted granted Critical
Publication of DK0796616T3 publication Critical patent/DK0796616T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Motorcycle And Bicycle Frame (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fats And Perfumes (AREA)
DK97301839T 1996-03-19 1997-03-19 Mikrosmådråbeformuleringer med propofol DK0796616T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/616,511 US5637625A (en) 1996-03-19 1996-03-19 Propofol microdroplet formulations

Publications (1)

Publication Number Publication Date
DK0796616T3 true DK0796616T3 (da) 1999-11-29

Family

ID=24469788

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97301839T DK0796616T3 (da) 1996-03-19 1997-03-19 Mikrosmådråbeformuleringer med propofol

Country Status (19)

Country Link
US (1) US5637625A (da)
EP (1) EP0796616B1 (da)
JP (1) JP2000507244A (da)
KR (1) KR100484516B1 (da)
CN (1) CN1124845C (da)
AT (1) ATE182074T1 (da)
AU (1) AU719756B2 (da)
BR (1) BR9708099B8 (da)
CA (1) CA2249375C (da)
DE (1) DE69700317T2 (da)
DK (1) DK0796616T3 (da)
ES (1) ES2135969T3 (da)
FI (1) FI982009A0 (da)
GR (1) GR3031414T3 (da)
HU (1) HU225046B1 (da)
NO (1) NO324498B1 (da)
NZ (1) NZ331669A (da)
RU (1) RU2186564C2 (da)
WO (1) WO1997034588A1 (da)

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US20070117862A1 (en) * 1993-02-22 2007-05-24 Desai Neil P Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
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US6465016B2 (en) * 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
CH692322A5 (it) * 1997-05-26 2002-05-15 Westy Ag Formulazione iniettabile limpida di Propofol.
HU230338B1 (hu) * 1997-06-27 2016-02-29 Abraxis Bioscience Llc Gyógyászati hatóanyagokat tartalmazó új készítmények, eljárás ilyen készítmények előállítására és alkalmazására
US6638621B2 (en) * 2000-08-16 2003-10-28 Lyotropic Therapeutics, Inc. Coated particles, methods of making and using
DE69936911T2 (de) 1998-02-10 2008-05-15 Sicor Inc., Irvine Propofolhaltiges arzneimittel enthaltend sulfite
CA2320807C (en) * 1998-02-11 2011-01-18 Research Triangle Pharmaceuticals Method and composition for treatment of inflammatory conditions
US6254853B1 (en) * 1998-05-08 2001-07-03 Vyrex Corporation Water soluble pro-drugs of propofol
EP1079808B1 (en) 1998-05-29 2004-02-11 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
US6204257B1 (en) 1998-08-07 2001-03-20 Universtiy Of Kansas Water soluble prodrugs of hindered alcohols
DK1105096T3 (da) * 1998-08-19 2004-03-08 Skyepharma Canada Inc Injicerbare vandige propofoldispersioner
US6150423A (en) 1998-10-15 2000-11-21 Phoenix Scientific, Inc. Propofol-based anesthetic and method of making same
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
WO2000030616A1 (en) 1998-11-20 2000-06-02 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
DE69922252T2 (de) * 1999-01-28 2005-12-01 Patel, Dinesh Shantilal Parenterale lösungen enthaltend propofol (2,6-diisopropylphenol) und 2.5-di-0-methyl-1.4;3.6-dianhydro-d-glucitol als lösungsmittel
US6177477B1 (en) * 1999-03-24 2001-01-23 American Home Products Corporation Propofol formulation containing TRIS
US6100302A (en) * 1999-04-05 2000-08-08 Baxter International Inc. Propofol formulation with enhanced microbial characteristics
GB2350297A (en) * 1999-05-27 2000-11-29 Abbott Lab Injectable halogenated anesthetic formulation in emulsion form
CN1174741C (zh) * 1999-09-21 2004-11-10 Rtp药品公司 生物活性物质的表面改性微粒组合物
US6071933A (en) * 1999-12-03 2000-06-06 Diversified Medical Innovations, Inc. Homogeneous remifentanil-propofol blend for patient controlled anesthesia and process for its use
GB2359747B (en) * 2000-02-29 2002-04-24 Maelor Pharmaceuticals Ltd Anaesthetic formulations
US6682761B2 (en) 2000-04-20 2004-01-27 Rtp Pharma, Inc. Water-insoluble drug particle process
IL153457A0 (en) 2000-06-16 2003-07-06 Skyepharma Canada Inc Improved injectable dispersions of propofol
US6623765B1 (en) 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
ES2325057T3 (es) 2000-08-31 2009-08-25 Jagotec Ag Particulas molturadas.
US8586094B2 (en) 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
EP1320362B1 (en) * 2000-09-20 2011-08-31 Jagotec AG Stabilised fibrate microparticles
ATE357216T1 (de) * 2001-02-22 2007-04-15 Jagotec Ag Fibrat-statin kombinationen mit verminderten von der nahrungsaufnahme abhängigen auswirkungen
WO2003000236A1 (en) 2001-06-23 2003-01-03 Lyotropic Therapeutics, Inc Particles with improved solubilization capacity
US20030054042A1 (en) * 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
JP2005504090A (ja) * 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
US6815555B2 (en) 2001-09-26 2004-11-09 Theravance, Inc. Substituted phenol compounds useful for anesthesia and sedation
US7112340B2 (en) * 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
PL205271B1 (pl) * 2001-12-28 2010-03-31 Mgi Gp Kompozycja farmaceutyczna rozpuszczalnego w wodzie proleku propofolu
EP1490030B2 (en) * 2002-03-20 2010-07-14 Elan Pharma International Limited Nanoparticulate compositions of angiogenesis inhibitors
US20080220075A1 (en) * 2002-03-20 2008-09-11 Elan Pharma International Ltd. Nanoparticulate compositions of angiogenesis inhibitors
EP1492544A4 (en) * 2002-04-08 2005-10-12 Guilford Pharm Inc PHARMACEUTICAL COMPOSITIONS CONTAINING PROPOFOL-BASED WATER-SOLUBLE PRODRUGS AND METHODS OF ADMINISTRATION THEREOF
US20040220283A1 (en) * 2002-07-29 2004-11-04 Transform Pharmaceuticals, Inc. Aqueous 2,6-diisopropylphenol pharmaceutical compositions
WO2004010941A2 (en) * 2002-07-29 2004-02-05 Transform Pharmaceuticals, Inc. Aqueous 2,6-diisopropylphenol pharmaceutical compositions
US7550155B2 (en) * 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
AU2003286725B2 (en) * 2002-10-29 2007-07-12 Transform Pharmaceuticals, Inc. Propofol with cysteine
EP1576953A4 (en) * 2002-12-06 2008-08-06 Otsuka Pharma Co Ltd FATTY EMULSIONS CONTAINING PROPOFOL
US20040225022A1 (en) * 2003-05-09 2004-11-11 Desai Neil P. Propofol formulation containing reduced oil and surfactants
US8476010B2 (en) 2003-07-10 2013-07-02 App Pharmaceuticals Llc Propofol formulations with non-reactive container closures
US7182948B2 (en) * 2003-08-04 2007-02-27 Ko Manufacturing, Inc. Topical veterinary compositions and methods for the treatment and prevention of infection
US20090060998A1 (en) * 2004-01-14 2009-03-05 Gilead Sciences, Inc. Lipid-based dispersions useful for drug delivery
US7125954B2 (en) 2005-01-27 2006-10-24 General Electric Company Method for producing polyether polymers
AU2006259594A1 (en) * 2005-06-14 2006-12-28 Baxter Healthcare S.A. Pharmaceutical formulations for minimizing drug-drug interactions
CN103054798B (zh) * 2005-08-31 2021-03-16 阿布拉科斯生物科学有限公司 用于制备稳定性增加的水难溶性药物的组合物和方法
WO2007027941A2 (en) * 2005-08-31 2007-03-08 Abraxis Bioscience, Llc. Compositions and methods for preparation of poorly water soluble drugs with increased stability
US20070134341A1 (en) * 2005-11-15 2007-06-14 Kipp James E Compositions of lipoxygenase inhibitors
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
RU2535001C1 (ru) * 2013-07-11 2014-12-10 Общество с ограниченной ответственностью "ВИК-здоровье животных" Микроколлоидный раствор пропофола для анестезии
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
JP2018527289A (ja) * 2015-06-01 2018-09-20 オートテリック・リミテッド・ライアビリティ・カンパニーＡｕｔｏｔｅｌｉｃ ＬＬＣ リン脂質でコーティングされた治療薬ナノ粒子および関連する方法
WO2017218630A2 (en) * 2016-06-15 2017-12-21 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
WO2021123117A1 (de) * 2019-12-20 2021-06-24 Fresenius Kabi Austria Gmbh Verfahren zur herstellung von öl-in-wasser-emulsionen
EP4056038A1 (en) * 2021-03-10 2022-09-14 Basf Se Microparticles containing active substances

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US4798846A (en) * 1974-03-28 1989-01-17 Imperial Chemical Industries Plc Pharmaceutical compositions
GB1472793A (en) * 1974-03-28 1977-05-04 Ici Ltd Pharmaceutical compositions
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
DE4132677C2 (de) * 1991-10-01 1995-08-24 Braun Melsungen Ag Flüchtige Inhalationsnarkotika enthaltende Liposomen, ihre Herstellung und Verwendung
GB9405593D0 (en) * 1994-03-22 1994-05-11 Zeneca Ltd Pharmaceutical compositions
US5496537A (en) * 1995-03-23 1996-03-05 Henry; Richard A. Propofol hydrofluorocarbon propellant formulations

Also Published As

Publication number Publication date
NO324498B1 (no) 2007-10-29
CN1218398A (zh) 1999-06-02
CN1124845C (zh) 2003-10-22
DE69700317T2 (de) 1999-12-02
HUP9902553A3 (en) 2001-04-28
DE69700317D1 (de) 1999-08-19
US5637625A (en) 1997-06-10
BR9708099A (pt) 2000-01-04
AU2329297A (en) 1997-10-10
AU719756B2 (en) 2000-05-18
ES2135969T3 (es) 1999-11-01
WO1997034588A1 (en) 1997-09-25
ATE182074T1 (de) 1999-07-15
BR9708099B8 (pt) 2014-04-29
RU2186564C2 (ru) 2002-08-10
JP2000507244A (ja) 2000-06-13
FI982009A (fi) 1998-09-17
KR100484516B1 (ko) 2005-09-02
EP0796616A1 (en) 1997-09-24
CA2249375C (en) 2002-06-18
HU225046B1 (hu) 2006-05-29
CA2249375A1 (en) 1997-09-25
HUP9902553A2 (hu) 2000-10-28
EP0796616B1 (en) 1999-07-14
GR3031414T3 (en) 2000-01-31
BR9708099B1 (pt) 2010-02-23
NZ331669A (en) 2000-01-28
FI982009A0 (fi) 1998-09-17
NO984370D0 (no) 1998-09-18
KR20000064762A (ko) 2000-11-06
NO984370L (no) 1998-09-18

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