DK0786459T3 - Fremgangsmåde til fremstilling af en heterobicyklisk alkoholenantiomer - Google Patents
Fremgangsmåde til fremstilling af en heterobicyklisk alkoholenantiomerInfo
- Publication number
- DK0786459T3 DK0786459T3 DK97200185T DK97200185T DK0786459T3 DK 0786459 T3 DK0786459 T3 DK 0786459T3 DK 97200185 T DK97200185 T DK 97200185T DK 97200185 T DK97200185 T DK 97200185T DK 0786459 T3 DK0786459 T3 DK 0786459T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- group
- compound
- chem
- general formula
- Prior art date
Links
- -1 heterobicyclic alcohol enantiomer Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 238000010511 deprotection reaction Methods 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 230000000707 stereoselective effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
- C07C67/287—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96200169 | 1996-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0786459T3 true DK0786459T3 (da) | 2003-01-06 |
Family
ID=8223609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97200185T DK0786459T3 (da) | 1996-01-25 | 1997-01-23 | Fremgangsmåde til fremstilling af en heterobicyklisk alkoholenantiomer |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5948909A (xx) |
| EP (1) | EP0786459B1 (xx) |
| JP (1) | JPH09216878A (xx) |
| KR (1) | KR100429320B1 (xx) |
| CN (1) | CN1139586C (xx) |
| AT (1) | ATE222902T1 (xx) |
| AU (1) | AU701883B2 (xx) |
| CA (1) | CA2195724C (xx) |
| CZ (1) | CZ20697A3 (xx) |
| DE (1) | DE69714875T2 (xx) |
| DK (1) | DK0786459T3 (xx) |
| ES (1) | ES2177891T3 (xx) |
| HK (1) | HK1000698A1 (xx) |
| HU (1) | HUP9700200A3 (xx) |
| IL (1) | IL120055A (xx) |
| NO (1) | NO315515B1 (xx) |
| NZ (1) | NZ314103A (xx) |
| PT (1) | PT786459E (xx) |
| RU (1) | RU2185379C2 (xx) |
| SK (1) | SK9997A3 (xx) |
| TW (1) | TW363059B (xx) |
| UA (1) | UA58483C2 (xx) |
| ZA (1) | ZA97530B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE246182T1 (de) * | 1997-05-12 | 2003-08-15 | Daiso Co Ltd | Verfahren zur herstellung von 1,4-benzodioxan- derivaten |
| KR100780538B1 (ko) * | 2006-08-02 | 2007-11-30 | 안국약품 주식회사 | 키랄 2-히드록시메틸-1,4-벤조디옥산 화합물의 제조방법 |
| WO2009087505A2 (en) * | 2007-12-31 | 2009-07-16 | Daniel Farb | Placing water turbines in water flows |
| WO2010079423A1 (en) * | 2009-01-12 | 2010-07-15 | Council Of Scientific & Industrial Research | Inhibitors of phosphatidylinositol-3-kinase (pi3) and inducers of nitric oxide (no) |
| FR2993881B1 (fr) * | 2012-07-26 | 2014-08-15 | Rhodia Operations | Procede de preparation d'alkoxyphenol et d'alkoxyhydroxybenzaldehyde |
| US9650322B2 (en) | 2012-07-26 | 2017-05-16 | Rhodia Operations | Method for producing alkoxyhydroxybenzaldehyde |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1137035B (de) * | 1960-04-29 | 1962-09-27 | Thomae Gmbh Dr K | Verfahren zur Herstellung von 2-Hydroxymethyl-8-hydroxy-1, 4-benzodioxan |
| DK0605033T3 (da) * | 1992-12-21 | 2000-02-07 | Duphar Int Res | Enzymatisk fremgangsmåde til stereoselektiv fremstilling af en heterobicyklisk alkoholenantiomer |
-
1997
- 1997-01-02 AU AU10018/97A patent/AU701883B2/en not_active Ceased
- 1997-01-22 NO NO19970281A patent/NO315515B1/no unknown
- 1997-01-22 ZA ZA97530A patent/ZA97530B/xx unknown
- 1997-01-22 CZ CZ97206A patent/CZ20697A3/cs unknown
- 1997-01-22 TW TW086100653A patent/TW363059B/zh active
- 1997-01-22 CA CA002195724A patent/CA2195724C/en not_active Expired - Fee Related
- 1997-01-22 JP JP9021903A patent/JPH09216878A/ja not_active Withdrawn
- 1997-01-22 SK SK99-97A patent/SK9997A3/sk unknown
- 1997-01-22 NZ NZ314103A patent/NZ314103A/en unknown
- 1997-01-22 KR KR1019970001682A patent/KR100429320B1/ko not_active IP Right Cessation
- 1997-01-22 HU HU9700200A patent/HUP9700200A3/hu unknown
- 1997-01-22 RU RU97100889/04A patent/RU2185379C2/ru not_active IP Right Cessation
- 1997-01-22 CN CNB971010358A patent/CN1139586C/zh not_active Expired - Fee Related
- 1997-01-22 US US08/786,306 patent/US5948909A/en not_active Expired - Fee Related
- 1997-01-23 AT AT97200185T patent/ATE222902T1/de not_active IP Right Cessation
- 1997-01-23 DK DK97200185T patent/DK0786459T3/da active
- 1997-01-23 PT PT97200185T patent/PT786459E/pt unknown
- 1997-01-23 DE DE69714875T patent/DE69714875T2/de not_active Expired - Fee Related
- 1997-01-23 IL IL12005597A patent/IL120055A/xx not_active IP Right Cessation
- 1997-01-23 EP EP97200185A patent/EP0786459B1/en not_active Expired - Lifetime
- 1997-01-23 ES ES97200185T patent/ES2177891T3/es not_active Expired - Lifetime
- 1997-01-24 UA UA97010299A patent/UA58483C2/uk unknown
- 1997-11-22 HK HK97102232A patent/HK1000698A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2195724A1 (en) | 1997-07-26 |
| DE69714875T2 (de) | 2003-04-30 |
| ZA97530B (en) | 1997-07-25 |
| EP0786459B1 (en) | 2002-08-28 |
| NZ314103A (en) | 1997-12-19 |
| NO970281D0 (no) | 1997-01-22 |
| AU1001897A (en) | 1997-07-31 |
| MX9700662A (es) | 1998-06-28 |
| DE69714875D1 (de) | 2002-10-02 |
| RU2185379C2 (ru) | 2002-07-20 |
| KR970059172A (ko) | 1997-08-12 |
| NO315515B1 (no) | 2003-09-15 |
| CN1139586C (zh) | 2004-02-25 |
| CA2195724C (en) | 2006-05-16 |
| HUP9700200A3 (en) | 1999-03-01 |
| AU701883B2 (en) | 1999-02-11 |
| IL120055A (en) | 2000-08-31 |
| CZ20697A3 (en) | 1997-08-13 |
| HUP9700200A2 (hu) | 1998-12-28 |
| UA58483C2 (uk) | 2003-08-15 |
| IL120055A0 (en) | 1997-04-15 |
| ATE222902T1 (de) | 2002-09-15 |
| EP0786459A1 (en) | 1997-07-30 |
| HU9700200D0 (en) | 1997-03-28 |
| SK9997A3 (en) | 1997-08-06 |
| NO970281L (no) | 1997-07-28 |
| ES2177891T3 (es) | 2002-12-16 |
| HK1000698A1 (en) | 2002-12-13 |
| TW363059B (en) | 1999-07-01 |
| CN1160714A (zh) | 1997-10-01 |
| PT786459E (pt) | 2003-01-31 |
| US5948909A (en) | 1999-09-07 |
| KR100429320B1 (ko) | 2005-09-26 |
| JPH09216878A (ja) | 1997-08-19 |
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