DK0754234T3 - DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II) - Google Patents

DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II)

Info

Publication number
DK0754234T3
DK0754234T3 DK95914256T DK95914256T DK0754234T3 DK 0754234 T3 DK0754234 T3 DK 0754234T3 DK 95914256 T DK95914256 T DK 95914256T DK 95914256 T DK95914256 T DK 95914256T DK 0754234 T3 DK0754234 T3 DK 0754234T3
Authority
DK
Denmark
Prior art keywords
icerel
cdna
recombinant
1beta
proteinase
Prior art date
Application number
DK95914256T
Other languages
Danish (da)
English (en)
Inventor
Donald W Nicholson
Ambereen Ali
Neil A Munday
John P Vaillancourt
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Application granted granted Critical
Publication of DK0754234T3 publication Critical patent/DK0754234T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK95914256T 1994-04-08 1995-04-04 DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II) DK0754234T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/225,487 US6110701A (en) 1994-04-08 1994-04-08 DNA encoding precursor of interleukin-1β converting enzyme--related cysteine proteinase II (ICErel -II)
PCT/CA1995/000188 WO1995027793A1 (en) 1994-04-08 1995-04-04 DNA ENCODING PRECURSOR OF INTERLEUKIN-1β CONVERTING ENZYME-RELATED CYSTEINE PROTEINASE II (ICErel-II)

Publications (1)

Publication Number Publication Date
DK0754234T3 true DK0754234T3 (da) 1999-11-29

Family

ID=22845077

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95914256T DK0754234T3 (da) 1994-04-08 1995-04-04 DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II)

Country Status (10)

Country Link
US (2) US6110701A (es)
EP (1) EP0754234B1 (es)
JP (1) JP3750136B2 (es)
AT (1) ATE182176T1 (es)
CA (1) CA2187161C (es)
DE (1) DE69510782T2 (es)
DK (1) DK0754234T3 (es)
ES (1) ES2136285T3 (es)
GR (1) GR3031468T3 (es)
WO (1) WO1995027793A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7250494A (en) * 1994-06-23 1996-01-19 Human Genome Sciences, Inc. Interleukin-1 beta converting enzyme like apoptosis protease-1 and 2
FR2723378B1 (fr) * 1994-08-02 1996-10-31 Roussel Uclaf Sequence d'adn codant pour une proteine humaine tx apparentee a l'enzyme de conversion de l'interleukine-1beta, proteine tx, procede de production, compositions pharmaceutiques et leurs applications
WO1996026280A1 (en) * 1995-02-21 1996-08-29 Basf Aktiengesellschaft NOVEL CYSTEINE PROTEASE RELATED TO INTERLEUKIN-1β CONVERTING ENZYME
US6121018A (en) * 1997-03-27 2000-09-19 Smithkline Beecham Corporation Interleukin-1β converting enzyme like apoptosis protease-10
EP1292697B1 (en) 2000-06-15 2009-07-22 SmithKline Beecham Corporation Method for preparing a physiologically active il-18 polypeptide
CN115772220B (zh) * 2022-11-22 2023-08-11 武汉爱博泰克生物科技有限公司 针对人白介素-1β的兔单克隆抗体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5416013A (en) * 1990-04-04 1995-05-16 Sterling Winthrop Inc. Interleukin 1β protease and interleukin 1β protease inhibitors
WO1993025685A1 (en) * 1992-06-12 1993-12-23 Massachusetts Institute Of Technology Cloning and characterization of the cell death genes ced-3 and ced-4
EP0672151A1 (en) * 1992-06-12 1995-09-20 Massachusetts Institute Of Technology Inhibitors of ced-3 and related proteins

Also Published As

Publication number Publication date
US6103513A (en) 2000-08-15
JPH09511646A (ja) 1997-11-25
US6110701A (en) 2000-08-29
JP3750136B2 (ja) 2006-03-01
ES2136285T3 (es) 1999-11-16
DE69510782D1 (de) 1999-08-19
CA2187161A1 (en) 1995-10-19
EP0754234A1 (en) 1997-01-22
EP0754234B1 (en) 1999-07-14
ATE182176T1 (de) 1999-07-15
CA2187161C (en) 2008-02-05
DE69510782T2 (de) 1999-12-30
WO1995027793A1 (en) 1995-10-19
GR3031468T3 (en) 2000-01-31

Similar Documents

Publication Publication Date Title
DE69939982D1 (de) B7l-1 moleküle
DE69942861D1 (de) Ldcam genannte moleküle
PT101297A (pt) Factores mitogenicos gliais, sua preparacao e utilizacao
FI875082A0 (fi) Dna-sekvensser deriverade fraon genom av papillomavirus, deras anvaendning foer in vitro diagnostiska aendamaol; samt framstaellning av antigeniska kompositioner.
ATE451462T1 (de) Klonierung und expression von htlv-iii-dns
DE59915205D1 (de) Strukturprotein von AAV, seine Herstellung und Verwendung
ATE393227T1 (de) Klonierung und charakterisierung von napsin, einer aspartat-protease
ES2059361T3 (es) Complejo de proteinas recombinantes que tiene actividad de factor viii:c su produccion y uso.
DK0759079T3 (da) DNA der koder precursor for interleukin-1beta-omdannende enzym-beslægtet cysteinproteinase III (ICErel-III)
ATE14936T1 (de) Verwendung von reagenzstreifen zur herstellung von reagenzloesungen.
AR014891A1 (es) Genes aislados de proteinas de membranas de mamiferos; reactivos relacionados
DK0754234T3 (da) DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II)
DE69836823D1 (de) Jmy, mit-aktivator für p300/cbp, dafür kodierendenucleinsäure und deren verwendungen
DK1082423T3 (da) Cyclin E2-gener og -proteiner
DE69405230D1 (de) Prostaglandinrezeptor ep1 kodierende dna
Henry et al. Co‐operation between metastatic tumor cells and macrophages in the degradation of basement membrane (type IV) collagen
DE69433385D1 (de) Für die untereinheiten der 1,3-beta-d-glucansynthase kodierende dna
DK0939769T3 (da) Vertebrat-Smoothened-proteiner
HUP9701904A2 (hu) D-panolakton hidroláz és az azt kódoló gén
DK130987A (da) Dna-fragment, som reagerer paa tilstedevaerelsen af methanol i dyrkningsmediet, vaertsorganisme derfor samt dets anvendelse
Koj et al. Substrate specificity and modifications of the active centre of elastase-like neutral proteinases from horse blood leucocytes
WO2004060867A3 (en) Secreted protein factor and cell membrane-bound splice variant
ATE302282T1 (de) Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen
EP0778347A3 (de) ATP- und Nukleinsäure-bindendes Protein mit putativen Helikase- und ATPase Eigenschaften
ATE408687T1 (de) Semaphorin polypeptide