DK0754234T3 - DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II) - Google Patents

DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II)

Info

Publication number
DK0754234T3
DK0754234T3 DK95914256T DK95914256T DK0754234T3 DK 0754234 T3 DK0754234 T3 DK 0754234T3 DK 95914256 T DK95914256 T DK 95914256T DK 95914256 T DK95914256 T DK 95914256T DK 0754234 T3 DK0754234 T3 DK 0754234T3
Authority
DK
Denmark
Prior art keywords
icerel
cdna
recombinant
1beta
proteinase
Prior art date
Application number
DK95914256T
Other languages
English (en)
Inventor
Donald W Nicholson
Ambereen Ali
Neil A Munday
John P Vaillancourt
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Application granted granted Critical
Publication of DK0754234T3 publication Critical patent/DK0754234T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK95914256T 1994-04-08 1995-04-04 DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II) DK0754234T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/225,487 US6110701A (en) 1994-04-08 1994-04-08 DNA encoding precursor of interleukin-1β converting enzyme--related cysteine proteinase II (ICErel -II)
PCT/CA1995/000188 WO1995027793A1 (en) 1994-04-08 1995-04-04 DNA ENCODING PRECURSOR OF INTERLEUKIN-1β CONVERTING ENZYME-RELATED CYSTEINE PROTEINASE II (ICErel-II)

Publications (1)

Publication Number Publication Date
DK0754234T3 true DK0754234T3 (da) 1999-11-29

Family

ID=22845077

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95914256T DK0754234T3 (da) 1994-04-08 1995-04-04 DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II)

Country Status (10)

Country Link
US (2) US6110701A (da)
EP (1) EP0754234B1 (da)
JP (1) JP3750136B2 (da)
AT (1) ATE182176T1 (da)
CA (1) CA2187161C (da)
DE (1) DE69510782T2 (da)
DK (1) DK0754234T3 (da)
ES (1) ES2136285T3 (da)
GR (1) GR3031468T3 (da)
WO (1) WO1995027793A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10501985A (ja) * 1994-06-23 1998-02-24 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド インターロイキン−１β変換酵素様アポトーシスプロテアーゼ−１および２
FR2723378B1 (fr) * 1994-08-02 1996-10-31 Roussel Uclaf Sequence d'adn codant pour une proteine humaine tx apparentee a l'enzyme de conversion de l'interleukine-1beta, proteine tx, procede de production, compositions pharmaceutiques et leurs applications
WO1996026280A1 (en) * 1995-02-21 1996-08-29 Basf Aktiengesellschaft NOVEL CYSTEINE PROTEASE RELATED TO INTERLEUKIN-1β CONVERTING ENZYME
US6121018A (en) * 1997-03-27 2000-09-19 Smithkline Beecham Corporation Interleukin-1β converting enzyme like apoptosis protease-10
ES2329875T3 (es) 2000-06-15 2009-12-02 Smithkline Beecham Corporation Procedimiento de preparacion de un polipeptido il-18 fisiologicamente activo.
CN115772220B (zh) * 2022-11-22 2023-08-11 武汉爱博泰克生物科技有限公司 针对人白介素-1β的兔单克隆抗体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5416013A (en) * 1990-04-04 1995-05-16 Sterling Winthrop Inc. Interleukin 1β protease and interleukin 1β protease inhibitors
EP0672151A1 (en) * 1992-06-12 1995-09-20 Massachusetts Institute Of Technology Inhibitors of ced-3 and related proteins
WO1993025685A1 (en) * 1992-06-12 1993-12-23 Massachusetts Institute Of Technology Cloning and characterization of the cell death genes ced-3 and ced-4

Also Published As

Publication number Publication date
GR3031468T3 (en) 2000-01-31
US6110701A (en) 2000-08-29
ES2136285T3 (es) 1999-11-16
EP0754234B1 (en) 1999-07-14
CA2187161C (en) 2008-02-05
DE69510782T2 (de) 1999-12-30
CA2187161A1 (en) 1995-10-19
WO1995027793A1 (en) 1995-10-19
DE69510782D1 (de) 1999-08-19
JP3750136B2 (ja) 2006-03-01
EP0754234A1 (en) 1997-01-22
ATE182176T1 (de) 1999-07-15
JPH09511646A (ja) 1997-11-25
US6103513A (en) 2000-08-15

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