DE69510782D1 - DNA, WELCHE FÜR DEN VORLÄUFER DES INTERLEUKIN-1 BETA KONVERTIERENDEN ENZYMS KODIERT (ICE rel-II) - Google Patents
DNA, WELCHE FÜR DEN VORLÄUFER DES INTERLEUKIN-1 BETA KONVERTIERENDEN ENZYMS KODIERT (ICE rel-II)Info
- Publication number
- DE69510782D1 DE69510782D1 DE69510782T DE69510782T DE69510782D1 DE 69510782 D1 DE69510782 D1 DE 69510782D1 DE 69510782 T DE69510782 T DE 69510782T DE 69510782 T DE69510782 T DE 69510782T DE 69510782 D1 DE69510782 D1 DE 69510782D1
- Authority
- DE
- Germany
- Prior art keywords
- icerel
- cdna
- recombinant
- precurrent
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
- C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/225,487 US6110701A (en) | 1994-04-08 | 1994-04-08 | DNA encoding precursor of interleukin-1β converting enzyme--related cysteine proteinase II (ICErel -II) |
PCT/CA1995/000188 WO1995027793A1 (en) | 1994-04-08 | 1995-04-04 | DNA ENCODING PRECURSOR OF INTERLEUKIN-1β CONVERTING ENZYME-RELATED CYSTEINE PROTEINASE II (ICErel-II) |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69510782D1 true DE69510782D1 (de) | 1999-08-19 |
DE69510782T2 DE69510782T2 (de) | 1999-12-30 |
Family
ID=22845077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69510782T Expired - Lifetime DE69510782T2 (de) | 1994-04-08 | 1995-04-04 | DNA, WELCHE FÜR DEN VORLÄUFER DES INTERLEUKIN-1 BETA KONVERTIERENDEN ENZYMS KODIERT (ICE rel-II) |
Country Status (10)
Country | Link |
---|---|
US (2) | US6110701A (de) |
EP (1) | EP0754234B1 (de) |
JP (1) | JP3750136B2 (de) |
AT (1) | ATE182176T1 (de) |
CA (1) | CA2187161C (de) |
DE (1) | DE69510782T2 (de) |
DK (1) | DK0754234T3 (de) |
ES (1) | ES2136285T3 (de) |
GR (1) | GR3031468T3 (de) |
WO (1) | WO1995027793A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7250494A (en) * | 1994-06-23 | 1996-01-19 | Human Genome Sciences, Inc. | Interleukin-1 beta converting enzyme like apoptosis protease-1 and 2 |
FR2723378B1 (fr) * | 1994-08-02 | 1996-10-31 | Roussel Uclaf | Sequence d'adn codant pour une proteine humaine tx apparentee a l'enzyme de conversion de l'interleukine-1beta, proteine tx, procede de production, compositions pharmaceutiques et leurs applications |
WO1996026280A1 (en) * | 1995-02-21 | 1996-08-29 | Basf Aktiengesellschaft | NOVEL CYSTEINE PROTEASE RELATED TO INTERLEUKIN-1β CONVERTING ENZYME |
US6121018A (en) * | 1997-03-27 | 2000-09-19 | Smithkline Beecham Corporation | Interleukin-1β converting enzyme like apoptosis protease-10 |
EP1292697B1 (de) | 2000-06-15 | 2009-07-22 | SmithKline Beecham Corporation | Verfahren zur herstellung eines physiologisch aktiven il-18 polypeptids |
CN115772220B (zh) * | 2022-11-22 | 2023-08-11 | 武汉爱博泰克生物科技有限公司 | 针对人白介素-1β的兔单克隆抗体及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5416013A (en) * | 1990-04-04 | 1995-05-16 | Sterling Winthrop Inc. | Interleukin 1β protease and interleukin 1β protease inhibitors |
WO1993025685A1 (en) * | 1992-06-12 | 1993-12-23 | Massachusetts Institute Of Technology | Cloning and characterization of the cell death genes ced-3 and ced-4 |
EP0672151A1 (de) * | 1992-06-12 | 1995-09-20 | Massachusetts Institute Of Technology | Inhibitoren von ced-3 und verwandte proteine |
-
1994
- 1994-04-08 US US08/225,487 patent/US6110701A/en not_active Expired - Fee Related
-
1995
- 1995-04-04 ES ES95914256T patent/ES2136285T3/es not_active Expired - Lifetime
- 1995-04-04 DE DE69510782T patent/DE69510782T2/de not_active Expired - Lifetime
- 1995-04-04 AT AT95914256T patent/ATE182176T1/de not_active IP Right Cessation
- 1995-04-04 EP EP95914256A patent/EP0754234B1/de not_active Expired - Lifetime
- 1995-04-04 JP JP52599295A patent/JP3750136B2/ja not_active Expired - Fee Related
- 1995-04-04 US US08/721,986 patent/US6103513A/en not_active Expired - Fee Related
- 1995-04-04 DK DK95914256T patent/DK0754234T3/da active
- 1995-04-04 WO PCT/CA1995/000188 patent/WO1995027793A1/en active IP Right Grant
- 1995-04-04 CA CA002187161A patent/CA2187161C/en not_active Expired - Fee Related
-
1999
- 1999-10-08 GR GR990402559T patent/GR3031468T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US6103513A (en) | 2000-08-15 |
JPH09511646A (ja) | 1997-11-25 |
US6110701A (en) | 2000-08-29 |
JP3750136B2 (ja) | 2006-03-01 |
ES2136285T3 (es) | 1999-11-16 |
CA2187161A1 (en) | 1995-10-19 |
EP0754234A1 (de) | 1997-01-22 |
DK0754234T3 (da) | 1999-11-29 |
EP0754234B1 (de) | 1999-07-14 |
ATE182176T1 (de) | 1999-07-15 |
CA2187161C (en) | 2008-02-05 |
DE69510782T2 (de) | 1999-12-30 |
WO1995027793A1 (en) | 1995-10-19 |
GR3031468T3 (en) | 2000-01-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69738653D1 (de) | Klonierung und charakterisierung von napsin, einer aspartat-protease | |
PT101297A (pt) | Factores mitogenicos gliais, sua preparacao e utilizacao | |
NZ323795A (en) | Isolated nucleic acid molecules encoding AUR-1 (aurora-1) and AUR-2 polypeptides | |
ES2059361T3 (es) | Complejo de proteinas recombinantes que tiene actividad de factor viii:c su produccion y uso. | |
WO1995009872B1 (en) | Dna encoding prostaglandin receptor ip | |
ATE415480T1 (de) | B7l-1 moleküle | |
DE69942861D1 (de) | Ldcam genannte moleküle | |
PT83255B (pt) | Polipeptidos e anticorpos, caracteristicos do polilomavirus e suas aplicacoes no diagnostico "in vitro" na pervencao e ou na luta contra as infeccoes por papilomavirus | |
DE69510791D1 (de) | DNA, WELCHE FÜR DEN VORLÄUFER DER INTERLEUKIN-1-BETA ÜBERFÜHRENDEN ENZYM-VERWANDTEN PROTEINASE III (ICE rel-III) KODIERT | |
WO1990003435A3 (fr) | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) humaine, et ses applications, notamment pour le diagnostic in vitro de l'hypertension arterielle | |
DE69510782D1 (de) | DNA, WELCHE FÜR DEN VORLÄUFER DES INTERLEUKIN-1 BETA KONVERTIERENDEN ENZYMS KODIERT (ICE rel-II) | |
Funakoshi et al. | Purification and properties of human pancreatic deoxyribonuclease I | |
Henry et al. | Co‐operation between metastatic tumor cells and macrophages in the degradation of basement membrane (type IV) collagen | |
Jima et al. | Collagenase activity in human saliva | |
Tanabe et al. | Degradation of enamelins by proteinases found in porcine secretory enamel in vitro | |
TR200201119T2 (tr) | İnsan alfa1G-C-türü kalsiyum kanalı kodlayan DNA. | |
Trachsel et al. | Purification of seven protein synthesis initiation factors from Krebs II ascites cells | |
Tanzer et al. | Inhibitory effects of tunacamycin on procollagen biosynthesis and secretion | |
Patrick et al. | An acetylcholine receptor preparation lacking the 42,000 Dalton component | |
WO2004060867A3 (en) | Secreted protein factor and cell membrane-bound splice variant | |
HUP0103208A2 (hu) | Proteáz kódoló szekvenciákat vagy inhibítoraikat tartalmazó DNS konstrukciók | |
CA2246430A1 (en) | Protein tyrosine phosphatases of hematopoietic cells | |
Simpson et al. | Synthesis of a collagenase inhibitor by gingival fibroblasts in culture | |
ATE266094T1 (de) | Produktion des proteins ingap mit hoher expressionsrate | |
DE69831242D1 (de) | Erhöhte herstellung von sekretierten proteinen durch rekombinante hefezellen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: MERCK FROSST CANADA LTD., KIRKLAND, QUEBEC, CA |