DK0759079T3 - DNA der koder precursor for interleukin-1beta-omdannende enzym-beslægtet cysteinproteinase III (ICErel-III) - Google Patents

DNA der koder precursor for interleukin-1beta-omdannende enzym-beslægtet cysteinproteinase III (ICErel-III)

Info

Publication number
DK0759079T3
DK0759079T3 DK95914255T DK95914255T DK0759079T3 DK 0759079 T3 DK0759079 T3 DK 0759079T3 DK 95914255 T DK95914255 T DK 95914255T DK 95914255 T DK95914255 T DK 95914255T DK 0759079 T3 DK0759079 T3 DK 0759079T3
Authority
DK
Denmark
Prior art keywords
iii
icerel
cdna
recombinant
1beta
Prior art date
Application number
DK95914255T
Other languages
English (en)
Inventor
Donald W Nicholson
Ambereen Ali
Neil A Munday
John P Vaillancourt
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Application granted granted Critical
Publication of DK0759079T3 publication Critical patent/DK0759079T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK95914255T 1994-04-08 1995-04-04 DNA der koder precursor for interleukin-1beta-omdannende enzym-beslægtet cysteinproteinase III (ICErel-III) DK0759079T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/224,930 US5552536A (en) 1994-04-08 1994-04-08 DNA encoding precursor of interleukin-1 beta converting enzyme - related cysteine proteinase III (ice rel-III)
PCT/CA1995/000187 WO1995027792A1 (en) 1994-04-08 1995-04-04 DNA ENCODING PRECURSOR OF INTERLEUKIN-1β CONVERTING ENZYME-RELATED CYSTEINE PROTEINASE III (ICErel-III)

Publications (1)

Publication Number Publication Date
DK0759079T3 true DK0759079T3 (da) 1999-11-29

Family

ID=22842824

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95914255T DK0759079T3 (da) 1994-04-08 1995-04-04 DNA der koder precursor for interleukin-1beta-omdannende enzym-beslægtet cysteinproteinase III (ICErel-III)

Country Status (10)

Country Link
US (2) US5552536A (da)
EP (1) EP0759079B1 (da)
JP (1) JP3815572B2 (da)
AT (1) ATE182177T1 (da)
CA (1) CA2187162C (da)
DE (1) DE69510791T2 (da)
DK (1) DK0759079T3 (da)
ES (1) ES2136284T3 (da)
GR (1) GR3031474T3 (da)
WO (1) WO1995027792A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715645B2 (en) * 1994-05-27 2014-05-06 The Regents Of The University Of Colorado Viral vectors encoding apoptosis-inducing proteins and methods for making and using the same
FR2723378B1 (fr) * 1994-08-02 1996-10-31 Roussel Uclaf Sequence d'adn codant pour une proteine humaine tx apparentee a l'enzyme de conversion de l'interleukine-1beta, proteine tx, procede de production, compositions pharmaceutiques et leurs applications
US6538121B1 (en) 1994-11-01 2003-03-25 Human Genome Sciences, Inc. Interleukin-1 β converting enzyme like apoptosis protease-3 and 4
US6835555B1 (en) 1994-11-01 2004-12-28 Human Genome Sciences, Inc. Interleukin-1 β converting enzyme like apoptosis protease-3 and 4
US5654146A (en) * 1995-05-31 1997-08-05 Incyte Pharmaceuticals, Inc. Human ice homolog
US6416753B1 (en) * 1996-03-15 2002-07-09 The General Hospital Corporation Method for modulating apoptosis
US5840509A (en) * 1996-07-22 1998-11-24 Eli Lilly And Company Protease and related nucleic acid compounds
US6063600A (en) * 1997-05-23 2000-05-16 Uab Research Foundation DNA encoding canine interleukin-1 receptor antagonist
WO2001098455A2 (en) 2000-06-15 2001-12-27 Smithkline Beecham Corporation Method for preparing a physiologically active il-18 polypeptide
EP4082761B1 (en) 2021-04-30 2024-03-27 DB Imagineering BV. Repair injector with support device for laminated glass

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5416013A (en) * 1990-04-04 1995-05-16 Sterling Winthrop Inc. Interleukin 1β protease and interleukin 1β protease inhibitors
JPH08500482A (ja) * 1992-06-12 1996-01-23 マサチューセッツ インスティテュート オブ テクノロジー Ｃｅｄ−３及び関連蛋白質のインヒビター
WO1993025685A1 (en) * 1992-06-12 1993-12-23 Massachusetts Institute Of Technology Cloning and characterization of the cell death genes ced-3 and ced-4
AU5102993A (en) * 1992-09-18 1994-04-12 Merck & Co., Inc. Dna encoding murine precursor interleukin 1beta converting enzyme

Also Published As

Publication number Publication date
ATE182177T1 (de) 1999-07-15
EP0759079A1 (en) 1997-02-26
DE69510791T2 (de) 1999-12-30
WO1995027792A1 (en) 1995-10-19
JPH09511645A (ja) 1997-11-25
US5552536A (en) 1996-09-03
US5760180A (en) 1998-06-02
ES2136284T3 (es) 1999-11-16
CA2187162C (en) 2008-06-17
JP3815572B2 (ja) 2006-08-30
DE69510791D1 (de) 1999-08-19
CA2187162A1 (en) 1995-10-19
GR3031474T3 (en) 2000-01-31
EP0759079B1 (en) 1999-07-14

Similar Documents

Publication Publication Date Title
ATE415480T1 (de) B7l-1 moleküle
ATE484587T1 (de) Ldcam genannte moleküle
DE69836088D1 (de) Als lerk6 bezeichnetes cytokin
PT101297A (pt) Factores mitogenicos gliais, sua preparacao e utilizacao
DE69738653D1 (de) Klonierung und charakterisierung von napsin, einer aspartat-protease
ATE500323T1 (de) Subtilisin-variante
DK0759079T3 (da) DNA der koder precursor for interleukin-1beta-omdannende enzym-beslægtet cysteinproteinase III (ICErel-III)
DE3688760D1 (de) Expression von faktor-vii-aktivitaet in saeugetierzellen.
ATE384787T1 (de) Tripeptidyl-aminopeptidase
PT83255B (pt) Polipeptidos e anticorpos, caracteristicos do polilomavirus e suas aplicacoes no diagnostico "in vitro" na pervencao e ou na luta contra as infeccoes por papilomavirus
DE69734204D1 (de) Lichtproduzierender biosensor
DK0754234T3 (da) DNA der koder precursor for interleukin-1beta-omdannende enzymbeslægtet cycteinproteinase II (ICErel-II)
PT1200561E (pt) Clone celular recombinante estavel, sua producao e utilizacao
DK0700437T3 (da) DNA, der koder for prostaglandin-receptor EP1
Henry et al. Co‐operation between metastatic tumor cells and macrophages in the degradation of basement membrane (type IV) collagen
FI971276A (fi) Lerk-6:ksi nimetty sytokiini
HUP9701904A2 (hu) D-panolakton hidroláz és az azt kódoló gén
DK0939769T3 (da) Vertebrat-Smoothened-proteiner
DK130987A (da) Dna-fragment, som reagerer paa tilstedevaerelsen af methanol i dyrkningsmediet, vaertsorganisme derfor samt dets anvendelse
NO985742D0 (no) IL-1/TNF-<alfa>-aktivert kinase (ITAK) og fremgangsmÕter for fremstilling og anvendelse av denne
ATE340188T1 (de) Transkriptionsfaktoren welche zwei potentielle dna bindende motive enthalten
ATE266094T1 (de) Produktion des proteins ingap mit hoher expressionsrate
PT870015E (pt) Novas xilanases os genes que as codificam e as suas utilizacoes
ATE408687T1 (de) Semaphorin polypeptide
SU1147981A1 (ru) Способ определени сульфгидрильных групп в гемсодержащих белках