DK0721453T3 - Fremgangsmåde til fremstilling af N-methyl-3-(1-methyl-4-piperidinyl)-14-indol-5-ethansulfonamid - Google Patents

Fremgangsmåde til fremstilling af N-methyl-3-(1-methyl-4-piperidinyl)-14-indol-5-ethansulfonamid

Info

Publication number
DK0721453T3
DK0721453T3 DK94928825T DK94928825T DK0721453T3 DK 0721453 T3 DK0721453 T3 DK 0721453T3 DK 94928825 T DK94928825 T DK 94928825T DK 94928825 T DK94928825 T DK 94928825T DK 0721453 T3 DK0721453 T3 DK 0721453T3
Authority
DK
Denmark
Prior art keywords
methyl
ethanesulfonamide
piperidinyl
indole
preparation
Prior art date
Application number
DK94928825T
Other languages
Danish (da)
English (en)
Inventor
Philip Blatcher
Malcolm Carter
Roy Hornby
Martin Richard Owen
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK0721453T3 publication Critical patent/DK0721453T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK94928825T 1993-09-29 1994-09-27 Fremgangsmåde til fremstilling af N-methyl-3-(1-methyl-4-piperidinyl)-14-indol-5-ethansulfonamid DK0721453T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939320115A GB9320115D0 (en) 1993-09-29 1993-09-29 Process
PCT/EP1994/003216 WO1995009166A1 (en) 1993-09-29 1994-09-27 Process for the preparation of n-methyl-3-(1-methyl-4-piperidinyl)-14-indole-5-ethanesulphonamide

Publications (1)

Publication Number Publication Date
DK0721453T3 true DK0721453T3 (da) 2003-03-17

Family

ID=10742727

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94928825T DK0721453T3 (da) 1993-09-29 1994-09-27 Fremgangsmåde til fremstilling af N-methyl-3-(1-methyl-4-piperidinyl)-14-indol-5-ethansulfonamid

Country Status (32)

Country Link
US (2) US5659040A (sv)
EP (1) EP0721453B1 (sv)
JP (1) JP3411284B2 (sv)
CN (2) CN1132509A (sv)
AP (1) AP529A (sv)
AT (1) ATE228124T1 (sv)
AU (1) AU682219B2 (sv)
CA (1) CA2170645C (sv)
CO (1) CO4290351A1 (sv)
CZ (1) CZ287581B6 (sv)
DE (1) DE69431759T2 (sv)
DK (1) DK0721453T3 (sv)
ES (1) ES2187534T3 (sv)
FI (1) FI111162B (sv)
GB (1) GB9320115D0 (sv)
HK (1) HK1004218A1 (sv)
HR (1) HRP940613B1 (sv)
HU (1) HU226828B1 (sv)
IL (1) IL111071A (sv)
IS (1) IS1877B (sv)
MY (1) MY117934A (sv)
NO (1) NO309324B1 (sv)
NZ (1) NZ274159A (sv)
PE (1) PE18195A1 (sv)
PL (1) PL178456B1 (sv)
PT (1) PT721453E (sv)
RU (1) RU2143428C1 (sv)
SG (1) SG49322A1 (sv)
SI (1) SI0721453T1 (sv)
SK (1) SK282234B6 (sv)
WO (1) WO1995009166A1 (sv)
ZA (1) ZA947516B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861448B2 (en) * 1998-01-14 2005-03-01 Virtual Drug Development, Inc. NAD synthetase inhibitors and uses thereof
EP1047692B1 (en) 1998-01-14 2004-07-21 The Uab Research Foundation Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof and methods of treating bacterial and microbial infections with these inhibitors
US6673827B1 (en) 1999-06-29 2004-01-06 The Uab Research Foundation Methods of treating fungal infections with inhibitors of NAD synthetase enzyme
WO2006010078A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Polymorphic form of naratriptan hydrochloride
WO2006010079A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Process for preparing naratriptan hydrochloride
CN1315821C (zh) * 2004-12-16 2007-05-16 上海美通生物科技有限公司 制备n-甲基-3-(1-甲基-4-哌啶基)-1,4-吲哚-5-乙硫胺的改进法
US20080015214A1 (en) * 2005-10-24 2008-01-17 Bignan Gilles C 3-piperidin-4-yl-indole orl-1 receptor modulators
WO2009118753A2 (en) * 2008-03-07 2009-10-01 Usv Limited Process for preparation of naratriptan hydrochloride
CN101676283A (zh) * 2008-09-17 2010-03-24 北京德众万全药物技术开发有限公司 一种那拉曲坦的制备方法
WO2011021000A2 (en) 2009-08-20 2011-02-24 Cipla Limited A process for the synthesis of naratriptan
CN101792411B (zh) * 2010-03-26 2012-05-30 常州晟永光电材料有限公司 一种合成乙磺酰胺的方法
CN103073484B (zh) * 2013-01-28 2014-10-22 山东诚创医药技术开发有限公司 一种甲哌卡因及其光学对映体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US4997841A (en) * 1987-08-13 1991-03-05 Glaxo Group Limited Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
MY117934A (en) 2004-08-30
WO1995009166A1 (en) 1995-04-06
EP0721453A1 (en) 1996-07-17
JP3411284B2 (ja) 2003-05-26
FI111162B (sv) 2003-06-13
HK1004218A1 (en) 1998-11-20
HU9600814D0 (en) 1996-05-28
SK40696A3 (en) 1996-10-02
PL178456B1 (pl) 2000-05-31
NO961252L (no) 1996-03-28
DE69431759D1 (de) 2003-01-02
CA2170645C (en) 2005-11-15
NO961252D0 (no) 1996-03-28
ATE228124T1 (de) 2002-12-15
US5659040A (en) 1997-08-19
CN1132509A (zh) 1996-10-02
CZ287581B6 (en) 2000-12-13
CO4290351A1 (es) 1996-04-17
JPH09502991A (ja) 1997-03-25
CZ76896A3 (en) 1996-06-12
US5786473A (en) 1998-07-28
RU2143428C1 (ru) 1999-12-27
ZA947516B (en) 1995-06-12
CN1332166A (zh) 2002-01-23
AU7810194A (en) 1995-04-18
IL111071A0 (en) 1994-11-28
PL313740A1 (en) 1996-07-22
NO309324B1 (no) 2001-01-15
HU226828B1 (en) 2009-11-30
PE18195A1 (es) 1995-07-27
AP9400676A0 (en) 1994-10-31
AU682219B2 (en) 1997-09-25
HRP940613A2 (en) 1997-06-30
FI961378A0 (sv) 1996-03-26
SK282234B6 (sk) 2001-12-03
ES2187534T3 (es) 2003-06-16
CA2170645A1 (en) 1995-04-06
NZ274159A (en) 1997-09-22
HUT75642A (en) 1997-05-28
IS1877B (is) 2003-06-20
SG49322A1 (en) 1998-05-18
PT721453E (pt) 2003-03-31
HRP940613B1 (en) 2003-10-31
IL111071A (en) 1998-10-30
DE69431759T2 (de) 2003-07-03
EP0721453B1 (en) 2002-11-20
IS4212A (is) 1995-03-30
FI961378A (sv) 1996-03-26
AP529A (en) 1996-09-09
SI0721453T1 (en) 2003-04-30
GB9320115D0 (en) 1993-11-17

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